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1NQ0
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TR Receptor Mutations Conferring Hormone Resistance and Reduced Corepressor Release Exhibit Decreased Stability in the Nterminal LBD
Descriptor: ARSENIC, Thyroid hormone receptor beta-1, [4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC ACID
Authors:Huber, B.R, Desclozeaux, M, West, B.L, Cunha-Lima, S.T, Nguyen, H.T, Baxter, J.D, Ingraham, H.A, Fletterick, R.J.
Deposit date:2003-01-20
Release date:2003-04-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Thyroid hormone receptor-beta mutations conferring hormone resistance and reduced corepressor release exhibit decreased stability in the N-terminal ligand-binding domain
Mol.Endocrinol., 17, 2003
1NQ1
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BU of 1nq1 by Molmil
TR Receptor Mutations Conferring Hormone Resistance and Reduced Corepressor Release Exhibit Decreased Stability in the Nterminal LBD
Descriptor: ARSENIC, Thyroid hormone receptor beta-1, [4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC ACID
Authors:Huber, B.R, Desclozeaux, M, West, B.L, Cunha-Lima, S.T, Nguyen, H.T, Baxter, J.D, Ingraham, H.A, Fletterick, R.J.
Deposit date:2003-01-20
Release date:2003-04-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Thyroid hormone receptor-beta mutations conferring hormone resistance and reduced corepressor release exhibit decreased stability in the N-terminal ligand-binding domain
Mol.Endocrinol., 17, 2003
1NQ2
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Two RTH Mutants with Impaired Hormone Binding
Descriptor: ARSENIC, SODIUM ION, Thyroid hormone receptor beta-1, ...
Authors:Huber, B.R, Sandler, B, West, B.L, Cunha-Lima, S.T, Nguyen, H.T, Apriletti, J.W, Baxter, J.D, Fletterick, R.J.
Deposit date:2003-01-21
Release date:2003-04-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Two resistance to thyroid hormone mutants with impaired hormone binding
Mol.Endocrinol., 17, 2003
1NQ3
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Crystal structure of the mammalian tumor associated antigen UK114
Descriptor: 14.3 kDa perchloric acid soluble protein
Authors:Deriu, D, Briand, C, Mistiniene, E, Naktinis, V, Grutter, M.G.
Deposit date:2003-01-21
Release date:2003-08-26
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and oligomeric state of the mammalian tumour-associated antigen UK114.
Acta Crystallogr.,Sect.D, 59, 2003
1NQ4
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Solution Structure of Oxytetracycline Acyl Carrier Protein
Descriptor: Oxytetracycline polyketide synthase acyl carrier protein
Authors:Findlow, S.C, Winsor, C, Simpson, T.J, Crosby, J, Crump, M.P.
Deposit date:2003-01-21
Release date:2003-11-04
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure and dynamics of oxytetracycline polyketide synthase acyl carrier protein from Streptomyces rimosus
Biochemistry, 42, 2003
1NQ5
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Glyceraldehyde-3-Phosphate Dehydrogenase Mutant With Cys 149 Replaced By Ser Complexed With Nad+
Descriptor: Glyceraldehyde 3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION
Authors:Didierjean, C, Corbier, C, Fatih, M, Favier, F, Boschi-Muller, S, Branlant, G, Aubry, A.
Deposit date:2003-01-21
Release date:2003-04-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Crystal structure of two ternary complexes of phosphorylating Glyceraldehyde-3-Phosphate Dehydrogenase from Bacillus stearothermophilus with NAD and D-Glyceraldehyde-3-Phosphate
J.Biol.Chem., 278, 2003
1NQ6
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Crystal Structure of the catalytic domain of xylanase A from Streptomyces halstedii JM8
Descriptor: MAGNESIUM ION, Xys1
Authors:Canals, A, Vega, M.C, Gomis-Ruth, F.X, Santamaria, R.I, Coll, M.
Deposit date:2003-01-21
Release date:2004-01-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structure of xylanase Xys1delta from Streptomyces halstedii.
Acta Crystallogr.,Sect.D, 59, 2003
1NQ7
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Characterization of ligands for the orphan nuclear receptor RORbeta
Descriptor: 7-(3,5-DITERT-BUTYLPHENYL)-3-METHYLOCTA-2,4,6-TRIENOIC ACID, NUCLEAR RECEPTOR ROR-BETA, STEROID RECEPTOR COACTIVATOR-1
Authors:Stehlin-Gaon, C, Willmann, D, Sanglier, S, Van Dorsselaer, A, Renaud, J.-P, Moras, D, Schuele, R.
Deposit date:2003-01-21
Release date:2003-09-23
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:All-trans retinoic acid is a ligand for the orphan nuclear receptor RORbeta
Nat.Struct.Biol., 10, 2003
1NQ9
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Crystal Structure of Antithrombin in the Pentasaccharide-Bound Intermediate State
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3,4-di-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-beta-D-glucopyranuronic acid-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-3-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2,3,6-tri-O-sulfo-alpha-D-glucopyranoside, ...
Authors:Huntington, J.A, Johnson, D.J.D.
Deposit date:2003-01-21
Release date:2003-09-30
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of Antithrombin in a Heparin-Bound Intermediate State
Biochemistry, 42, 2003
1NQA
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Glyceraldehyde-3-Phosphate Dehydrogenase Mutant With Cys 149 Replaced By Ala Complexed With Nad+ and D-Glyceraldehyde-3-Phosphate
Descriptor: GLYCERALDEHYDE-3-PHOSPHATE, Glyceraldehyde 3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Didierjean, C, Corbier, C, Fatih, M, Favier, F, Boschi-Muller, S, Branlant, G, Aubry, A.
Deposit date:2003-01-21
Release date:2003-04-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of two ternary complexes of phosphorylating Glyceraldehyde-3-Phosphate Dehydrogenase from Bacillus stearothermophilus with NAD and D-Glyceraldehyde-3-Phosphate
J.Biol.Chem., 278, 2003
1NQB
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TRIVALENT ANTIBODY FRAGMENT
Descriptor: SINGLE-CHAIN ANTIBODY FRAGMENT
Authors:Williams, R.L, Pei, X.Y.
Deposit date:1997-04-04
Release date:1997-08-20
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:The 2.0-A resolution crystal structure of a trimeric antibody fragment with noncognate VH-VL domain pairs shows a rearrangement of VH CDR3.
Proc.Natl.Acad.Sci.USA, 94, 1997
1NQC
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Crystal structures of Cathepsin S inhibitor complexes
Descriptor: Cathepsin S, N-[(1R)-2-(BENZYLSULFANYL)-1-FORMYLETHYL]-N-(MORPHOLIN-4-YLCARBONYL)-L-PHENYLALANINAMIDE
Authors:Pauly, T.A, Sulea, T, Ammirati, M, Sivaraman, J, Danley, D.E, Griffor, M.C, Kamath, A.V, Wang, I.K, Laird, E.R, Menard, R, Cygler, M, Rath, V.L.
Deposit date:2003-01-21
Release date:2003-04-15
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Specificity determinants of human cathepsin s revealed by crystal structures of complexes.
Biochemistry, 42, 2003
1NQD
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CRYSTAL STRUCTURE OF CLOSTRIDIUM HISTOLYTICUM COLG COLLAGENASE COLLAGEN-BINDING DOMAIN 3B AT 1.65 ANGSTROM RESOLUTION IN PRESENCE OF CALCIUM
Descriptor: CALCIUM ION, class 1 collagenase
Authors:Wilson, J.J, Matsushita, O, Okabe, A, Sakon, J.
Deposit date:2003-01-21
Release date:2003-04-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A Bacterial Collagen-Binding Domain with Novel Calcium-Binding Motif Controls Domain Orientation
Embo J., 22, 2003
1NQE
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OUTER MEMBRANE COBALAMIN TRANSPORTER (BTUB) FROM E. COLI
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, MAGNESIUM ION, Vitamin B12 receptor
Authors:Chimento, D.P, Mohanty, A.K, Kadner, R.J, Wiener, M.C.
Deposit date:2003-01-21
Release date:2003-04-29
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Substrate-induced transmembrane signaling in the cobalamin transporter BtuB
Nat.Struct.Biol., 10, 2003
1NQF
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OUTER MEMBRANE COBALAMIN TRANSPORTER (BTUB) FROM E. COLI, METHIONINE SUBSTIUTION CONSTRUCT FOR SE-MET SAD PHASING
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, MAGNESIUM ION, Vitamin B12 receptor
Authors:Chimento, D.P, Mohanty, A.K, Kadner, R.J, Wiener, M.C.
Deposit date:2003-01-21
Release date:2003-04-29
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Substrate-induced transmembrane signaling in the cobalamin transporter BtuB
Nat.Struct.Biol., 10, 2003
1NQG
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OUTER MEMBRANE COBALAMIN TRANSPORTER (BTUB) FROM E. COLI, WITH BOUND CALCIUM
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, CALCIUM ION, vitamin b12 receptor
Authors:Chimento, D.P, Mohanty, A.K, Kadner, R.J, Wiener, M.C.
Deposit date:2003-01-21
Release date:2003-04-29
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Substrate-induced transmembrane signaling in the cobalamin transporter BtuB
Nat.Struct.Biol., 10, 2003
1NQH
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OUTER MEMBRANE COBALAMIN TRANSPORTER (BTUB) FROM E. COLI, WITH BOUND CALCIUM AND CYANOCOBALAMIN (VITAMIN B12) SUBSTRATE
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, CALCIUM ION, CYANOCOBALAMIN, ...
Authors:Chimento, D.P, Mohanty, A.K, Kadner, R.J, Wiener, M.C.
Deposit date:2003-01-21
Release date:2003-04-29
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Substrate-induced transmembrane signaling in the cobalamin transporter BtuB
Nat.Struct.Biol., 10, 2003
1NQI
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crystal structure of lactose synthase, a 1:1 complex between beta1,4-galactosyltransferase and alpha-lactalbumin in the presence of GlcNAc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-LACTALBUMIN, BETA-1,4-GALACTOSYLTRANSFERASE, ...
Authors:Ramakrishnan, B, Qasba, P.K.
Deposit date:2003-01-21
Release date:2003-02-04
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of lactose synthase reveals a large conformational change in its catalytic component, the beta-1,4-galactosyltransferase
J.Mol.Biol., 310, 2001
1NQJ
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CRYSTAL STRUCTURE OF CLOSTRIDIUM HISTOLYTICUM COLG COLLAGENASE COLLAGEN-BINDING DOMAIN 3B AT 1.0 ANGSTROM RESOLUTION IN ABSENCE OF CALCIUM
Descriptor: CHLORIDE ION, LITHIUM ION, class 1 collagenase
Authors:Wilson, J.J, Matsushita, O, Okabe, A, Sakon, J.
Deposit date:2003-01-21
Release date:2003-04-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1 Å)
Cite:A bacterial collagen-binding domain with novel calcium-binding motif controls domain orientation
Embo J., 22, 2003
1NQK
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Structural Genomics, Crystal structure of Alkanesulfonate monooxygenase
Descriptor: Alkanesulfonate monooxygenase
Authors:Zhang, R, Skarina, T, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2003-01-21
Release date:2003-09-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of the protein Alkanesulfonate monooxygenase from E. Coli
To be Published
1NQL
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Structure of the extracellular domain of human epidermal growth factor (EGF) receptor in an inactive (low pH) complex with EGF.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ferguson, K.M, Lemmon, M.A.
Deposit date:2003-01-21
Release date:2003-03-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:EGF activates its receptor by removing interactions that auto-inhibit ectodomain dimerization
Mol.Cell, 11, 2003
1NQM
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Structure of Savm-W120K, streptavidin mutant
Descriptor: BIOTIN, Streptavidin
Authors:Pazy, Y, Eisenberg-Domovich, Y, Laitinen, O.H, Kulomaa, M.S, Bayer, E.A, Wilchek, M, Livnah, O.
Deposit date:2003-01-22
Release date:2003-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Dimer-Tetramer Transition between Solution and Crystalline States of Streptavidin and Avidin Mutants.
J.Bacteriol., 185, 2003
1NQN
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Structure of Avm-W110K (W110K mutant of avidin)
Descriptor: Avidin
Authors:Pazy, Y, Eisenberg-Domovich, Y, Laitinen, O.H, Kulomaa, M.S, Bayer, E.A, Wilchek, M, Livnah, O.
Deposit date:2003-01-22
Release date:2003-07-15
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Dimer-Tetramer Transition between Solution and Crystalline States of Streptavidin and Avidin Mutants.
J.Bacteriol., 185, 2003
1NQO
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Glyceraldehyde-3-Phosphate Dehydrogenase Mutant With Cys 149 Replaced By Ser Complexed With Nad+ and D-Glyceraldehyde-3-Phosphate
Descriptor: GLYCERALDEHYDE-3-PHOSPHATE, Glyceraldehyde 3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Didierjean, C, Corbier, C, Fatih, M, Favier, F, Boschi-Muller, S, Branlant, G, Aubry, A.
Deposit date:2003-01-22
Release date:2003-04-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Crystal structure of two ternary complexes of phosphorylating Glyceraldehyde-3-Phosphate Dehydrogenase from Bacillus stearothermophilus with NAD and D-Glyceraldehyde-3-Phosphate
J.Biol.Chem., 278, 2003
1NQP
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Crystal structure of Human hemoglobin E at 1.73 A resolution
Descriptor: CYANIDE ION, Hemoglobin alpha chain, Hemoglobin beta chain, ...
Authors:Dasgupta, J, Sen, U, Choudhury, D, Dutta, P, Basu, S, Chakrabarti, A, Chakrabarty, A, Dattagupta, J.K.
Deposit date:2003-01-22
Release date:2004-03-02
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Crystallization and preliminary X-ray structural Studies of Hemoglobin A2 and Hemoglobin E, isolated from the blood samples of Beta-thalassemic patients
Biochem.Biophys.Res.Commun., 303, 2004

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数据于2024-11-06公开中

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