1NQ7

Characterization of ligands for the orphan nuclear receptor RORbeta

Summary for 1NQ7
DescriptorNUCLEAR RECEPTOR ROR-BETA, STEROID RECEPTOR COACTIVATOR-1, 7-(3,5-DITERT-BUTYLPHENYL)-3-METHYLOCTA-2,4,6-TRIENOIC ACID, ... (4 entities in total)
Functional Keywordsligand-binding domain, retinoids, retinoic acid, synthetic ligand, antagonist, transcription
Biological sourceRattus norvegicus (Norway rat)
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Cellular locationNucleus (Probable): P45446
Total number of polymer chains2
Total formula weight29798.67
Authors
Stehlin-Gaon, C.,Willmann, D.,Sanglier, S.,Van Dorsselaer, A.,Renaud, J.-P.,Moras, D.,Schuele, R. (deposition date: 2003-01-21, release date: 2003-09-23, Last modification date: 2011-07-13)
Primary citationMoras, D.,Renaud, J.-P.,Sanglier, S.,Schuele, R.,Stehlin-Gaon, C.,Van Dorsselaer, A.,Willmann, D.,Zeyer, D.
All-trans retinoic acid is a ligand for the orphan nuclear receptor RORbeta
Nat.Struct.Biol., 10:820-825, 2003
PubMed: 12958591
DOI: 110.1038/nsb979
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.5 Å)
Structure validation
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PDB entries from 2021-06-16