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5W7X
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BU of 5w7x by Molmil
Crystal Structure of FHA domain of human APLF in complex with XRCC1 bisphospho peptide
Descriptor: Aprataxin and PNK-like factor, DNA repair protein XRCC1
Authors:Pedersen, L.C, Kim, K, London, R.E.
Deposit date:2017-06-21
Release date:2018-05-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.005 Å)
Cite:Characterization of the APLF FHA-XRCC1 phosphopeptide interaction and its structural and functional implications.
Nucleic Acids Res., 45, 2017
2N3X
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BU of 2n3x by Molmil
Solution Structure of TDP-43 Amyloidogenic Core Region
Descriptor: TAR DNA-binding protein 43
Authors:Jiang, L, Zhao, J, Zhou, C, Hu, H.
Deposit date:2015-06-11
Release date:2016-04-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Two mutations G335D and Q343R within the amyloidogenic core region of TDP-43 influence its aggregation and inclusion formation
Sci Rep, 6, 2016
3VAG
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BU of 3vag by Molmil
Structure of U2AF65 variant with BrU3C2 DNA
Descriptor: 1,4-DIETHYLENE DIOXIDE, DNA 5'-D(*U*CP*(BRU)P*UP*UP*UP*U)-3', GLYCEROL, ...
Authors:Jenkins, J.L, Kielkopf, C.L.
Deposit date:2011-12-29
Release date:2013-02-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.
Nucleic Acids Res., 41, 2013
7C9C
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BU of 7c9c by Molmil
Human DMC1 pre-synaptic complexes
Descriptor: CALCIUM ION, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Meiotic recombination protein DMC1/LIM15 homolog, ...
Authors:Luo, S.C, Yeh, H.Y, Chi, P, Ho, M.C, Tsai, M.D.
Deposit date:2020-06-05
Release date:2020-11-25
Last modified:2021-01-27
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures.
Nat Commun, 12, 2021
7C98
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BU of 7c98 by Molmil
Human DMC1 post-synaptic complexes
Descriptor: CALCIUM ION, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ...
Authors:Luo, S.C, Yeh, H.Y, Chi, P, Ho, M.C, Tsai, M.D.
Deposit date:2020-06-05
Release date:2020-11-18
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures.
Nat Commun, 12, 2021
1QKJ
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BU of 1qkj by Molmil
T4 Phage B-Glucosyltransferase, Substrate Binding and Proposed Catalytic Mechanism
Descriptor: BETA-GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE
Authors:Morera, S, Imberty, I, Aschke-Sonnenborn, U, Ruger, W, Freemont, P.S.
Deposit date:1999-07-22
Release date:1999-07-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:T4 Phage Beta-Glucosyltransferase: Substrate Binding and Proposed Catalytic Mechanism
J.Mol.Biol., 292, 1999
2N4G
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BU of 2n4g by Molmil
Solution Structure of the G335D Mutant of TDP-43 Amyloidogenic Core Region
Descriptor: TAR DNA-binding protein 43
Authors:Jiang, L, Zhao, J, Hu, H.
Deposit date:2015-06-17
Release date:2016-04-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Two mutations G335D and Q343R within the amyloidogenic core region of TDP-43 influence its aggregation and inclusion formation
Sci Rep, 6, 2016
4HIV
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BU of 4hiv by Molmil
Structure of actinomycin D d(ATGCGGCAT) complex
Descriptor: ACTINOMYCIN D, DNA (5'-D(*AP*TP*GP*CP*GP*GP*CP*AP*T)-3')
Authors:Lo, Y.S, Tseng, W.H, Hou, M.H.
Deposit date:2012-10-12
Release date:2013-05-08
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The structural basis of actinomycin D-binding induces nucleotide flipping out, a sharp bend and a left-handed twist in CGG triplet repeats.
Nucleic Acids Res., 41, 2013
5Y59
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BU of 5y59 by Molmil
Crystal structure of Ku80 and Sir4
Descriptor: ATP-dependent DNA helicase II subunit 2, SULFATE ION, Sir4p
Authors:Chen, H, Xue, J, Wu, J, Lei, M.
Deposit date:2017-08-08
Release date:2017-12-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:Structural Insights into Yeast Telomerase Recruitment to Telomeres
Cell, 172, 2018
8BQ2
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BU of 8bq2 by Molmil
CryoEM structure of the pre-synaptic RAD51 nucleoprotein filament in the presence of ATP and Ca2+
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (30-MER), ...
Authors:Appleby, R, Bollschweiler, D, Pellegrini, L.
Deposit date:2022-11-18
Release date:2023-05-03
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:A metal ion-dependent mechanism of RAD51 nucleoprotein filament disassembly.
Iscience, 26, 2023
8BR2
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BU of 8br2 by Molmil
CryoEM structure of the post-synaptic RAD51 nucleoprotein filament in the presence of ATP and Ca2+
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(P*GP*CP*GP*AP*GP*CP*TP*CP*GP*AP*TP*GP*CP*AP*CP*CP*TP*CP*CP*A)-3'), ...
Authors:Appleby, R, Bollschweiler, D, Pellegrini, L.
Deposit date:2022-11-22
Release date:2023-05-03
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:A metal ion-dependent mechanism of RAD51 nucleoprotein filament disassembly.
Iscience, 26, 2023
7YOZ
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BU of 7yoz by Molmil
Cryo-EM structure of human subnucleosome (intermediate form)
Descriptor: Histone H3.1, Histone H4, Widom601 DNA FW (145-MER), ...
Authors:Nozawa, K, Takizawa, Y, Kurumizaka, H.
Deposit date:2022-08-02
Release date:2022-11-16
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Cryo-electron microscopy structure of the H3-H4 octasome: A nucleosome-like particle without histones H2A and H2B.
Proc.Natl.Acad.Sci.USA, 119, 2022
8K26
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BU of 8k26 by Molmil
Structure of Cas1-Cas2 complex
Descriptor: Cas1, HD Cas3-type domain-containing protein
Authors:Zhang, L.X, Feng, Y.
Deposit date:2023-07-12
Release date:2024-07-17
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of csy complex with short DNA
To Be Published
7ENN
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BU of 7enn by Molmil
The structure of ALC1 bound to the nucleosome
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromodomain-helicase-DNA-binding protein 1-like, ...
Authors:Chen, Z.C, Chen, K.J, Wang, L.
Deposit date:2021-04-18
Release date:2021-07-14
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis of ALC1/CHD1L autoinhibition and the mechanism of activation by the nucleosome.
Nat Commun, 12, 2021
3MUD
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BU of 3mud by Molmil
Structure of the Tropomyosin Overlap Complex from Chicken Smooth Muscle
Descriptor: 1,2-ETHANEDIOL, DNA repair protein XRCC4,Tropomyosin alpha-1 chain, SULFATE ION, ...
Authors:Klenchin, V.A, Frye, J, Rayment, I.
Deposit date:2010-05-02
Release date:2010-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the tropomyosin overlap complex from chicken smooth muscle: insight into the diversity of N-terminal recognition .
Biochemistry, 49, 2010
6AVK
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BU of 6avk by Molmil
Streptavidin bound to peptide-like compound KPM-6
Descriptor: 1-hydroxydodecan-4-one, N-[(2H-1,3-benzodioxol-5-yl)methyl]-2-({[(2H-1,3-benzodioxol-5-yl)methyl][2-(chloromethyl)-1,3-oxazole-4-carbonyl]amino}methyl)-N-[(4-carbamoyl-1,3-oxazol-2-yl)methyl]-1,3-oxazole-4-carboxamide, Streptavidin
Authors:Park, H, Shamim, R, McEnaney, P, Kodadek, T.
Deposit date:2017-09-02
Release date:2018-08-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Efficient Workflow for Screening DNA-encoded One Bead One Compound Libraries Using a Flow Cytometer
To be Published
6CFH
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BU of 6cfh by Molmil
SWGMMGMLASQ segment from the low complexity domain of TDP-43
Descriptor: TAR DNA-binding protein 43
Authors:Guenther, E.L, Rodriguez, J.A, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2018-02-15
Release date:2018-05-23
Last modified:2024-05-15
Method:ELECTRON CRYSTALLOGRAPHY (1.5 Å)
Cite:Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
2ZJ5
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BU of 2zj5 by Molmil
Archaeal DNA helicase Hjm complexed with ADP in form 1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Putative ski2-type helicase, SULFATE ION
Authors:Oyama, T, Oka, H, Fujikane, R, Ishino, Y, Morikawa, K.
Deposit date:2008-02-29
Release date:2009-02-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Atomic structures and functional implications of the archaeal RecQ-like helicase Hjm
Bmc Struct.Biol., 9, 2009
2ZJA
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BU of 2zja by Molmil
Archaeal DNA helicase Hjm complexed with AMPPCP in form 2
Descriptor: PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Putative ski2-type helicase
Authors:Oyama, T, Oka, H, Fujikane, R, Ishino, Y, Morikawa, K.
Deposit date:2008-02-29
Release date:2009-02-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Atomic structures and functional implications of the archaeal RecQ-like helicase Hjm
Bmc Struct.Biol., 9, 2009
2G88
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BU of 2g88 by Molmil
MSRECA-dATP COMPLEX
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CITRIC ACID, MAGNESIUM ION, ...
Authors:Krishna, R, Manjunath, G.P, Kumar, P, Surolia, A, Chandra, N.R, Muniyappa, K, Vijayan, M.
Deposit date:2006-03-02
Release date:2006-05-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystallographic identification of an ordered C-terminal domain and a second nucleotide-binding site in RecA: new insights into allostery.
Nucleic Acids Res., 34, 2006
2ZJ2
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BU of 2zj2 by Molmil
Archaeal DNA helicase Hjm apo state in form 1
Descriptor: Putative ski2-type helicase, SULFATE ION
Authors:Oyama, T, Oka, H, Fujikane, R, Ishino, Y, Morikawa, K.
Deposit date:2008-02-29
Release date:2009-02-10
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Atomic structures and functional implications of the archaeal RecQ-like helicase Hjm
Bmc Struct.Biol., 9, 2009
2ZJ8
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BU of 2zj8 by Molmil
Archaeal DNA helicase Hjm apo state in form 2
Descriptor: Putative ski2-type helicase
Authors:Oyama, T, Oka, H, Fujikane, R, Ishino, Y, Morikawa, K.
Deposit date:2008-02-29
Release date:2009-02-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Atomic structures and functional implications of the archaeal RecQ-like helicase Hjm
Bmc Struct.Biol., 9, 2009
381D
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BU of 381d by Molmil
BINDING OF THE MODIFIED DAUNORUBICIN WP401 ADJACENT TO A T-G BASE PAIR INDUCES THE REVERSE WATSON-CRICK CONFORMATION: CRYSTAL STRUCTURES OF THE WP401-TGGCCG AND WP401-CGG[BR5C]CG COMPLEXES
Descriptor: 2'-BROMO-4'-EPIDAUNORUBICIN, DNA (5'-D(*TP*GP*(G49)P*CP*CP*G)-3'), DNA (5'-D(*TP*GP*GP*CP*CP*G)-3')
Authors:Dutta, R, Gao, Y.-G, Priebe, W, Wang, A.H.-J.
Deposit date:1998-02-18
Release date:1998-07-13
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Binding of the modified daunorubicin WP401 adjacent to a T-G base pair induces the reverse Watson-Crick conformation: crystal structures of the WP401-TGGCCG and WP401-CGG[br5C]CG complexes.
Nucleic Acids Res., 26, 1998
1DL4
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BU of 1dl4 by Molmil
THE SOLUTION STRUCTURE OF A BAY-REGION 1S-BENZ[A]ANTHRACENE OXIDE ADDUCT AT THE N6 POSITION OF ADENINE OF AN OLIGODEOXYNUCLEOTIDE CONTAINING THE HUMAN N-RAS CODON 61 SEQUENCE
Descriptor: 1R,2S,3R,4S-TETRAHYDRO-BENZO[A]ANTHRACENE-2,3,4-TRIOL, DNA (5'-D(*CP*GP*GP*AP*CP*(BZA)AP*AP*GP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP*G)-3')
Authors:Li, Z, Kim, H.-Y, Tamura, P.J, Harris, C.M, Harris, T.M, Stone, M.P.
Deposit date:1999-12-08
Release date:2000-01-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Intercalation of the (1S,2R,3S,4R)-N6-[1-(1,2,3,4-tetrahydro-2,3, 4-trihydroxybenz[a]anthracenyl)]-2'-deoxyadenosyl adduct in an oligodeoxynucleotide containing the human N-ras codon 61 sequence.
Biochemistry, 38, 1999
4RE7
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BU of 4re7 by Molmil
Lambda-[Ru(TAP)2(dppz)]2+ bound to d(TCIGCGCCGA)
Descriptor: 5'-D(*TP*CP*IP*GP*CP*GP*CP*CP*GP*A)-3', BARIUM ION, Ru(tap)2(dppz) complex
Authors:Hall, J.P, Cardin, C.J.
Deposit date:2014-09-22
Release date:2015-09-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.181 Å)
Cite:The effects of DNA modification on the binding of polypyridyl ruthenium complexes
To be Published

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数据于2024-10-09公开中

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