2CG3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2cg3 by Molmil](/molmil-images/mine/2cg3) | Crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa. | Descriptor: | SDSA1, ZINC ION | Authors: | Hagelueken, G, Adams, T.M, Wiehlmann, L, Widow, U, Kolmar, H, Tuemmler, B, Heinz, D.W, Schubert, W.-D. | Deposit date: | 2006-02-27 | Release date: | 2006-04-26 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The Crystal Structure of Sdsa1, an Alkylsulfatase from Pseudomonas Aeruginosa, Defines a Third Third Class of Sulfatases Proc.Natl.Acad.Sci.USA, 103, 2006
|
|
2B0J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2b0j by Molmil](/molmil-images/mine/2b0j) | The crystal structure of the apoenzyme of the iron-sulfur-cluster-free hydrogenase (Hmd) | Descriptor: | 5,10-methenyltetrahydromethanopterin hydrogenase | Authors: | Pilak, O, Mamat, B, Vogt, S, Hagemeier, C.H, Thauer, R.K, Shima, S, Vonrhein, C, Warkentin, E, Ermler, U. | Deposit date: | 2005-09-14 | Release date: | 2006-04-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The Crystal Structure of the Apoenzyme of the Iron-Sulphur Cluster-free Hydrogenase J.Mol.Biol., 358, 2006
|
|
2FJB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fjb by Molmil](/molmil-images/mine/2fjb) | Adenosine-5'-phosphosulfate reductase im complex with products | Descriptor: | (S)-10-((2S,3S,4R)-5-((S)-((S)-(((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHOXY)(HYDROXY)PHOSPHORYLOXY)(HYDROXY)PHOSPHORYLOXY)-2,3,4-TRIHYDROXYPENTYL)-7,8-DIMETHYL-2,4-DIOXO-2,3,4,4A-TETRAHYDROBENZO[G]PTERIDINE-5(10H)-SULFONIC ACID, ADENOSINE MONOPHOSPHATE, IRON/SULFUR CLUSTER, ... | Authors: | Schiffer, A, Fritz, G, Kroneck, P.M, Ermler, U. | Deposit date: | 2006-01-02 | Release date: | 2006-03-28 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Reaction mechanism of the iron-sulfur flavoenzyme adenosine-5'-phosphosulfate reductase based on the structural characterization of different enzymatic states Biochemistry, 45, 2006
|
|
2ESY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2esy by Molmil](/molmil-images/mine/2esy) | Structure and influence on stability and activity of the N-terminal propetide part of lung surfactant protein C | Descriptor: | lung surfactant protein C | Authors: | Li, J, Liepinsh, E, Almlen, A, Thyberg, J, Curstedt, T, Jornvall, H, Johansson, J. | Deposit date: | 2005-10-27 | Release date: | 2005-11-15 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Structure and influence on stability and activity of the N-terminal propeptide part of lung surfactant protein C Febs J., 273, 2006
|
|
2FHJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fhj by Molmil](/molmil-images/mine/2fhj) | Crystal structure of formylmethanofuran: tetrahydromethanopterin formyltransferase in complex with its coenzymes | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, 5-(4-{[1-(2-AMINO-5-FORMYL-7-METHYL-4-OXO-3,4,5,6,7,8-HEXAHYDROPTERIDIN-6-YL)ETHYL]AMINO}PHENYL)-5-DEOXY-1-O-{5-O-[(1,3-DICARBOXYPROPOXY)(HYDROXY)PHOSPHORYL]PENTOFURANOSYL}PENTITOL, ... | Authors: | Acharya, P, Warkentin, E, Thauer, R.K, Shima, S, Ermler, U. | Deposit date: | 2005-12-25 | Release date: | 2006-03-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structure of formylmethanofuran: tetrahydromethanopterin formyltransferase in complex with its coenzymes J.Mol.Biol., 357, 2006
|
|
2FJE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fje by Molmil](/molmil-images/mine/2fje) | adenosine-5-phosphosulfate reductase oxidized state | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, IRON/SULFUR CLUSTER, adenylylsulfate reductase, ... | Authors: | Schiffer, A, Fritz, G, Kroneck, P.M, Ermler, U. | Deposit date: | 2006-01-02 | Release date: | 2006-03-28 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Reaction mechanism of the iron-sulfur flavoenzyme adenosine-5'-phosphosulfate reductase based on the structural characterization of different enzymatic states Biochemistry, 45, 2006
|
|
2FJD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fjd by Molmil](/molmil-images/mine/2fjd) | adenosine-5-phosphosulfate reductase in complex with sulfite (covalent adduct) | Descriptor: | (S)-10-((2S,3S,4R)-5-((S)-((S)-(((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHOXY)(HYDROXY)PHOSPHORYLOXY)(HYDROXY)PHOSPHORYLOXY)-2,3,4-TRIHYDROXYPENTYL)-7,8-DIMETHYL-2,4-DIOXO-2,3,4,4A-TETRAHYDROBENZO[G]PTERIDINE-5(10H)-SULFONIC ACID, IRON/SULFUR CLUSTER, adenylylsulfate reductase, ... | Authors: | Schiffer, A, Fritz, G, Kroneck, P.M, Ermler, U. | Deposit date: | 2006-01-02 | Release date: | 2006-03-28 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Reaction mechanism of the iron-sulfur flavoenzyme adenosine-5'-phosphosulfate reductase based on the structural characterization of different enzymatic states Biochemistry, 45, 2006
|
|
2FJA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fja by Molmil](/molmil-images/mine/2fja) | adenosine 5'-phosphosulfate reductase in complex with substrate | Descriptor: | ADENOSINE-5'-PHOSPHOSULFATE, FLAVIN-ADENINE DINUCLEOTIDE, IRON/SULFUR CLUSTER, ... | Authors: | Schiffer, A, Fritz, G, Kroneck, P.M, Ermler, U. | Deposit date: | 2006-01-02 | Release date: | 2006-03-28 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Reaction mechanism of the iron-sulfur flavoenzyme adenosine-5'-phosphosulfate reductase based on the structural characterization of different enzymatic states Biochemistry, 45, 2006
|
|
2FHK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fhk by Molmil](/molmil-images/mine/2fhk) | Crystal structure of formylmethanofuran: tetrahydromethanopterin formyltransferase in complex with its coenzymes | Descriptor: | Formylmethanofuran--tetrahydromethanopterin formyltransferase, N-[4,5,7-TRICARBOXYHEPTANOYL]-L-GAMMA-GLUTAMYL-N-{2-[4-({5-[(FORMYLAMINO)METHYL]-3-FURYL}METHOXY)PHENYL]ETHYL}-D-GLUTAMINE, POTASSIUM ION | Authors: | Acharya, P, Warkentin, E, Thauer, R.K, Shima, S, Ermler, U. | Deposit date: | 2005-12-25 | Release date: | 2006-03-07 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structure of formylmethanofuran: tetrahydromethanopterin formyltransferase in complex with its coenzymes J.Mol.Biol., 357, 2006
|
|
2JWD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jwd by Molmil](/molmil-images/mine/2jwd) | protein A | Descriptor: | Immunoglobulin G-binding protein A | Authors: | Robertson, A, Horne, J, Scanlon, M.J, Bottomley, S.P. | Deposit date: | 2007-10-09 | Release date: | 2008-10-21 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Polyglutamine length-dependent midfolding is confined to the Poly-Q region To be Published
|
|
2JDO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jdo by Molmil](/molmil-images/mine/2jdo) | STRUCTURE OF PKB-BETA (AKT2) COMPLEXED WITH ISOQUINOLINE-5-SULFONIC ACID (2-(2-(4-CHLOROBENZYLOXY) ETHYLAMINO)ETHYL)AMIDE | Descriptor: | 1,2-ETHANEDIOL, GLYCOGEN SYNTHASE KINASE-3 BETA, ISOQUINOLINE-5-SULFONIC ACID (2-(2-(4-CHLOROBENZYLOXY)ETHYLAMINO)ETHYL)AMIDE, ... | Authors: | Davies, T.G, Verdonk, M.L, Graham, B, Saalau-Bethell, S, Hamlett, C.C.F, Mchardy, T, Collins, I, Garrett, M.D, Workman, P, Woodhead, S.J, Jhoti, H, Barford, D. | Deposit date: | 2007-01-11 | Release date: | 2007-02-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A Structural Comparison of Inhibitor Binding to Pkb, Pka and Pka-Pkb Chimera J.Mol.Biol., 367, 2007
|
|
5LAA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5laa by Molmil](/molmil-images/mine/5laa) | |
1WZ9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1wz9 by Molmil](/molmil-images/mine/1wz9) | The 2.1 A structure of a tumour suppressing serpin | Descriptor: | Maspin precursor, SULFATE ION | Authors: | Law, R.H, Irving, J.A, Buckle, A.M, Ruzyla, K, Buzza, M, Bashtannyk-Puhalovich, T.A, Beddoe, T.C, Kim, N, Worrall, D.M, Bottomley, S.P, Bird, P.I, Rossjohn, J, Whisstock, J.C. | Deposit date: | 2005-03-03 | Release date: | 2005-03-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix. J.Biol.Chem., 280, 2005
|
|
1JAX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jax by Molmil](/molmil-images/mine/1jax) | Structure of Coenzyme F420H2:NADP+ Oxidoreductase (FNO) | Descriptor: | MAGNESIUM ION, SODIUM ION, conserved hypothetical protein | Authors: | Warkentin, E, Mamat, B, Thauer, R, Ermler, U, Shima, S. | Deposit date: | 2001-06-01 | Release date: | 2001-12-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structures of F420H2:NADP+ oxidoreductase with and without its substrates bound. EMBO J., 20, 2001
|
|
1K1G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1k1g by Molmil](/molmil-images/mine/1k1g) | STRUCTURAL BASIS FOR RECOGNITION OF THE INTRON BRANCH SITE RNA BY SPLICING FACTOR 1 | Descriptor: | 5'-R(*UP*AP*UP*AP*CP*UP*AP*AP*CP*AP*A)-3', SF1-Bo isoform | Authors: | Liu, Z, Luyten, I, Bottomley, M.J, Messias, A.C, Houngninou-Molango, S, Sprangers, R, Zanier, K, Kramer, A, Sattler, M. | Deposit date: | 2001-09-25 | Release date: | 2001-11-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural basis for recognition of the intron branch site RNA by splicing factor 1. Science, 294, 2001
|
|
2JDS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jds by Molmil](/molmil-images/mine/2jds) | Structure of cAMP-dependent protein kinase complexed with A-443654 | Descriptor: | (2S)-1-(1H-INDOL-3-YL)-3-{[5-(3-METHYL-1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE, CAMP-DEPENDENT PROTEIN KINASE, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA | Authors: | Davies, T.G, Verdonk, M.L, Graham, B, Saalau-Bethell, S, Hamlett, C.C.F, McHardy, T, Collins, I, Garrett, M.D, Workman, P, Woodhead, S.J, Jhoti, H, Barford, D. | Deposit date: | 2007-01-12 | Release date: | 2007-02-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A Structural Comparison of Inhibitor Binding to Pkb, Pka and Pka-Pkb Chimera J.Mol.Biol., 367, 2007
|
|
2JDT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jdt by Molmil](/molmil-images/mine/2jdt) | Structure of PKA-PKB chimera complexed with ISOQUINOLINE-5-SULFONIC ACID (2-(2-(4-CHLOROBENZYLOXY) ETHYLAMINO)ETHYL)AMIDE | Descriptor: | CAMP-DEPENDENT PROTEIN KINASE, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA, ISOQUINOLINE-5-SULFONIC ACID (2-(2-(4-CHLOROBENZYLOXY)ETHYLAMINO)ETHYL)AMIDE | Authors: | Davies, T.G, Verdonk, M.L, Graham, B, Saalau-Bethell, S, Hamlett, C.C.F, McHardy, T, Collins, I, Garrett, M.D, Workman, P, Woodhead, S.J, Jhoti, H, Barford, D. | Deposit date: | 2007-01-12 | Release date: | 2007-02-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | A Structural Comparison of Inhibitor Binding to Pkb, Pka and Pka-Pkb Chimera J.Mol.Biol., 367, 2007
|
|
2I2X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2i2x by Molmil](/molmil-images/mine/2i2x) | Crystal structure of methanol:cobalamin methyltransferase complex MtaBC from Methanosarcina barkeri | Descriptor: | 5-HYDROXYBENZIMIDAZOLYLCOB(III)AMIDE, Methyltransferase 1, POTASSIUM ION, ... | Authors: | Hagemeier, C.H, Kruer, M, Thauer, R.K, Warkentin, E, Ermler, U. | Deposit date: | 2006-08-17 | Release date: | 2006-11-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Insight into the mechanism of biological methanol activation based on the crystal structure of the methanol-cobalamin methyltransferase complex Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
1YXA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yxa by Molmil](/molmil-images/mine/1yxa) | Serpina3n, a murine orthologue of human antichymotrypsin | Descriptor: | serine (or cysteine) proteinase inhibitor, clade A, member 3N | Authors: | Horvath, A.J, Irving, J.A, Law, R.H, Rossjohn, J, Bottomley, S.P, Quinsey, N.S, Pike, R.N, Coughlin, P.B, Whisstock, J.C. | Deposit date: | 2005-02-20 | Release date: | 2005-09-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The murine orthologue of human antichymotrypsin: a structural paradigm for clade A3 serpins. J.Biol.Chem., 280, 2005
|
|
1Z47
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1z47 by Molmil](/molmil-images/mine/1z47) | Structure of the ATPase subunit CysA of the putative sulfate ATP-binding cassette (ABC) transporter from Alicyclobacillus acidocaldarius | Descriptor: | CHLORIDE ION, putative ABC-transporter ATP-binding protein | Authors: | Scheffel, F, Demmer, U, Warkentin, E, Huelsmann, A, Schneider, E, Ermler, U. | Deposit date: | 2005-03-15 | Release date: | 2005-06-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the ATPase subunit CysA of the putative sulfate ATP-binding cassette (ABC) transporter from Alicyclobacillus acidocaldarius Febs Lett., 579, 2005
|
|
1ZHA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zha by Molmil](/molmil-images/mine/1zha) | A. aeolicus KDO8PS R106G mutant in complex with PEP and R5P | Descriptor: | 2-dehydro-3-deoxyphosphooctonate aldolase, CADMIUM ION, PHOSPHATE ION, ... | Authors: | Xu, X, Kona, F, Wang, J, Lu, J, Stemmler, T, Gatti, D.L. | Deposit date: | 2005-04-25 | Release date: | 2005-09-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | The Catalytic and Conformational Cycle of Aquifex aeolicus KDO8P Synthase: Role of the L7 Loop. Biochemistry, 44, 2005
|
|
1Y60
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1y60 by Molmil](/molmil-images/mine/1y60) | Structure of the tetrahydromethanopterin dependent formaldehyde-activating enzyme (Fae) from Methylobacterium extorquens AM1 with bound 5,10-methylene tetrahydromethanopterin | Descriptor: | 5,10-DIMETHYLENE TETRAHYDROMETHANOPTERIN, Formaldehyde-activating enzyme fae | Authors: | Acharya, P, Goenrich, M, Hagemeier, C.H, Demmer, U, Vorholt, J.A, Thauer, R.K, Ermler, U. | Deposit date: | 2004-12-03 | Release date: | 2005-01-11 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | How an enzyme binds the C1-carrier tetrahydromethanopterin: Structure of the tetrahydromethanopterin dependent formaldehyde-activating enzyme (Fae) from Methylobacterium extorquens AM1 J.Biol.Chem., 280, 2005
|
|
1XW9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xw9 by Molmil](/molmil-images/mine/1xw9) | Drosophila thioredoxin, oxidized, P21 | Descriptor: | thioredoxin | Authors: | Wahl, M.C, Irmler, A, Hecker, B, Schirmer, R.H, Becker, K. | Deposit date: | 2004-10-29 | Release date: | 2004-11-16 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Comparative structural analysis of oxidized and reduced thioredoxin from Drosophila melanogaster J.Mol.Biol., 345, 2005
|
|
1XWC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xwc by Molmil](/molmil-images/mine/1xwc) | Drosophila thioredoxin, reduced, P6522 | Descriptor: | thioredoxin | Authors: | Wahl, M.C, Irmler, A, Hecker, B, Schirmer, R.H, Becker, K. | Deposit date: | 2004-10-29 | Release date: | 2004-11-16 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Comparative structural analysis of oxidized and reduced thioredoxin from Drosophila melanogaster J.Mol.Biol., 345, 2005
|
|
1Z69
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1z69 by Molmil](/molmil-images/mine/1z69) | Crystal structure of methylenetetrahydromethanopterin reductase (Mer) in complex with coenzyme F420 | Descriptor: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, CHLORIDE ION, COENZYME F420, ... | Authors: | Aufhammer, S.W, Warkentin, E, Ermler, U, Hagemeier, C.H, Thauer, R.K, Shima, S. | Deposit date: | 2005-03-22 | Release date: | 2005-06-21 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Crystal structure of methylenetetrahydromethanopterin reductase (Mer) in complex with coenzyme F420: Architecture of the F420/FMN binding site of enzymes within the nonprolyl cis-peptide containing bacterial luciferase family Protein Sci., 14, 2005
|
|