PDB: 153 resultsInfo pagesStatus searchChemie searchBIRD

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6XJU	Crystal Structure of KPT-8602 bound to CRM1 (E582K, 537-DLTVK-541 to GLCEQ) Descriptor: (2R)-3-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-2-(pyrimidin-5-yl)propanamide, Exportin-1, GTP-binding nuclear protein Ran, ... Authors: Baumhardt, J.M, Chook, Y.M. Deposit date: 2020-06-24 Release date: 2021-01-27 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.193 Å) Cite: Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia. J Hematol Oncol, 14, 2021
5UWR	Crystal Structure of CDC7 NES Peptide (extended) in complex with CRM1-Ran-RanBP1 Descriptor: CHLORIDE ION, Cell division cycle 7-related protein kinase, Exportin-1, ... Authors: Fung, H.Y.J, Chook, Y.M. Deposit date: 2017-02-21 Release date: 2017-03-22 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.24 Å) Cite: Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017
6XJS	Crystal Structure of KPT-330 bound to CRM1 (E582K, 537-DLTVK-541 to GLCEQ) Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ... Authors: Baumhardt, J.M, Chook, Y.M. Deposit date: 2020-06-24 Release date: 2021-01-27 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.942 Å) Cite: Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia. J Hematol Oncol, 14, 2021
5UWU	Crystal Structure of SMAD4 NES Peptide in complex with CRM1-Ran-RanBP1 Descriptor: CHLORIDE ION, Exportin-1, GLYCEROL, ... Authors: Fung, H.Y.J, Chook, Y.M. Deposit date: 2017-02-21 Release date: 2017-03-22 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.24 Å) Cite: Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017
5UWI	Crystal Structure of HDAC5 NES Peptide in complex with CRM1-Ran-RanBP1 Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ... Authors: Fung, H.Y.J, Chook, Y.M. Deposit date: 2017-02-21 Release date: 2017-03-22 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.143 Å) Cite: Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017
6XJT	Crystal Structure of KPT-8602 bound to CRM1 (537-DLTVK-541 to GLCEQ) Descriptor: (2R)-3-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-2-(pyrimidin-5-yl)propanamide, Exportin-1, GTP-binding nuclear protein Ran, ... Authors: Baumhardt, J.M, Chook, Y.M. Deposit date: 2020-06-24 Release date: 2021-01-27 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.406 Å) Cite: Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia. J Hematol Oncol, 14, 2021
5W0V	Crystal structure of full-length Kluyveromyces lactis Kap123 with histone H4 1-34 Descriptor: Histone H4 1-34, Kap123 Authors: An, S, Yoon, J, Song, J.-J, Cho, U.-S. Deposit date: 2017-05-31 Release date: 2017-11-01 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.821 Å) Cite: Structure-based nuclear import mechanism of histones H3 and H4 mediated by Kap123. Elife, 6, 2017
5UWQ	Crystal Structure of CDC7 NES Peptide in complex with CRM1-Ran-RanBP1 Descriptor: Cell division cycle 7-related protein kinase, Exportin-1, GLYCEROL, ... Authors: Fung, H.Y.J, Chook, Y.M. Deposit date: 2017-02-21 Release date: 2017-03-22 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.278 Å) Cite: Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017
5UWP	Crystal Structure of mDia2 NES Peptide in complex with CRM1-Ran-RanBP1 Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ... Authors: Fung, H.Y.J, Chook, Y.M. Deposit date: 2017-02-21 Release date: 2017-03-22 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.054 Å) Cite: Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017
5UWO	Crystal Structure of Engineered FMRP-1b NES Peptide in complex with CRM1-Ran-RanBP1 Descriptor: Engineered FMRP-1b peptide, Exportin-1, GLYCEROL, ... Authors: Fung, H.Y.J, Chook, Y.M. Deposit date: 2017-02-21 Release date: 2017-03-22 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.347 Å) Cite: Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017
5UWH	Crystal Structure of Paxillin NES Peptide in complex with CRM1-Ran-RanBP1 Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ... Authors: Fung, H.Y.J, Chook, Y.M. Deposit date: 2017-02-21 Release date: 2017-03-22 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.26 Å) Cite: Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017
5UWT	Crystal Structure of Hxk2 Peptide in complex with CRM1 K579A mutant-Ran-RanBP1 Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ... Authors: Fung, H.Y.J, Chook, Y.M. Deposit date: 2017-02-21 Release date: 2017-03-22 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.342 Å) Cite: Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017
5VCH	Crystal structure of full-length Kluyveromyces lactis Kap123 Descriptor: Kap123 Authors: An, S, Yoon, J, Song, J.-J, Cho, U.-S. Deposit date: 2017-03-31 Release date: 2017-11-01 Last modified: 2022-03-16 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structure-based nuclear import mechanism of histones H3 and H4 mediated by Kap123. Elife, 6, 2017
5YRO	RanL182A in complex with RanBP1-CRM1 Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1,Exportin-1, ... Authors: Sun, Q, Zhang, Y. Deposit date: 2017-11-09 Release date: 2018-11-21 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.396 Å) Cite: RanL182A in complex with RanBP1-CRM1 To Be Published
5YTB	RanY197A in complex with RanBP1-CRM1 Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... Authors: Sun, Q, Zhang, Y. Deposit date: 2017-11-17 Release date: 2018-11-21 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (2.3 Å) Cite: RanY197A in complex with RanBP1-CRM1 To Be Published
5YVG	Crystal structure of Karyopherin beta2 in complex with FUS(full length) Descriptor: RNA-binding protein FUS, Transportin-1 Authors: Yoshizawa, T, Fung, H.Y.J, Chook, Y.M. Deposit date: 2017-11-25 Release date: 2018-05-16 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (4.05 Å) Cite: Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell, 173, 2018
5ZPU	LFS829 in complex with CRM1-Ran-RanBP1 Descriptor: (Z)-{[(3E)-4-{(R)-[3,5-bis(trifluoromethyl)phenyl]sulfinyl}but-3-en-1-yl]imino}methanethiol, CHLORIDE ION, Exportin-1,Exportin-1, ... Authors: Sun, Q, Lei, Y. Deposit date: 2018-04-16 Release date: 2019-04-17 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.6 Å) Cite: To be published To Be Published
6A3A	MVM NES mutant Nm2 in complex with CRM1-Ran-RanBP1 Descriptor: 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ... Authors: Sun, Q, Li, Y. Deposit date: 2018-06-15 Release date: 2019-06-19 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
6A3E	MVM NES mutant Nm15 in complex with CRM1-Ran-RanBP1 Descriptor: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Sun, Q, Li, Y. Deposit date: 2018-06-15 Release date: 2019-06-19 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
6A3B	MVM NES mutant Nm13 in complex with CRM1-Ran-RanBP1 Descriptor: 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ... Authors: Sun, Q, Li, Y. Deposit date: 2018-06-15 Release date: 2019-06-19 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.51 Å) Cite: Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
5YVH	Crystal structure of Karyopherin beta2 in complex with FUS(371-526) Descriptor: RNA-binding protein FUS, Transportin-1 Authors: Yoshizawa, T, Fung, H.Y.J, Chook, Y.M. Deposit date: 2017-11-25 Release date: 2018-05-16 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell, 173, 2018
5YU6	CRYSTAL STRUCTURE OF EXPORTIN-5:RANGTP COMPLEX Descriptor: 13-mer peptide, Exportin-5, GTP-binding nuclear protein Ran, ... Authors: Yamazawa, R, Jiko, C, Lee, S.J, Yamashita, E. Deposit date: 2017-11-20 Release date: 2018-08-29 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.997 Å) Cite: Structural Basis for Selective Binding of Export Cargoes by Exportin-5 Structure, 26, 2018
5YVI	Crystal structure of Karyopherin beta2 in complex with FUS(456-526) Descriptor: RNA-binding protein FUS, Transportin-1 Authors: Yoshizawa, T, Fung, H.Y.J, Chook, Y.M. Deposit date: 2017-11-25 Release date: 2018-05-16 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell, 173, 2018
5XOJ	Crystal structure of Xpo1p-PKI-Nup42p-Gsp1p-GTP complex Descriptor: Exportin-1, GTP-binding nuclear protein, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Koyama, M, Shirai, N, Matsuura, Y. Deposit date: 2017-05-29 Release date: 2017-08-16 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of the Xpo1p nuclear export complex bound to the SxFG/PxFG repeats of the nucleoporin Nup42p Genes Cells, 22, 2017
6A38	MVM NS2 NES in complex with CRM1-Ran-RanBP1 Descriptor: 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ... Authors: Sun, Q, Li, Y. Deposit date: 2018-06-15 Release date: 2019-06-19 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.69 Å) Cite: Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021

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