PDB: 161 resultsInfo pagesStatus searchChemie searchBIRD

---

5RZ8	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z1263714198 Descriptor: 1,2-ETHANEDIOL, 1-[(1,2-oxazol-3-yl)methyl]piperazine, DIMETHYL SULFOXIDE, ... Authors: Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2020-10-30 Release date: 2020-11-11 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.66 Å) Cite: EPB41L3 PanDDA analysis group deposition To Be Published
5RZO	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z2856434925 Descriptor: 1,2-ETHANEDIOL, 4-[(5-chloro-1,2,3-thiadiazol-4-yl)methyl]morpholine, DIMETHYL SULFOXIDE, ... Authors: Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2020-10-30 Release date: 2020-11-11 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.97 Å) Cite: EPB41L3 PanDDA analysis group deposition To Be Published
5RYO	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z136583524 Descriptor: 1,2-ETHANEDIOL, 2-methyl-N-(pyridin-4-yl)furan-3-carboxamide, DIMETHYL SULFOXIDE, ... Authors: Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2020-10-30 Release date: 2020-11-11 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.58 Å) Cite: EPB41L3 PanDDA analysis group deposition To Be Published
5RYX	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z2234920345 Descriptor: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Isoform 2 of Band 4.1-like protein 3, ... Authors: Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2020-10-30 Release date: 2020-11-11 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.63 Å) Cite: EPB41L3 PanDDA analysis group deposition To Be Published
5RZE	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z2856434786 Descriptor: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Isoform 2 of Band 4.1-like protein 3, ... Authors: Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2020-10-30 Release date: 2020-11-11 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.69 Å) Cite: EPB41L3 PanDDA analysis group deposition To Be Published
5RZX	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z2856434814 Descriptor: 1,2-ETHANEDIOL, 3-(diethylamino)phenol, DIMETHYL SULFOXIDE, ... Authors: Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2020-10-30 Release date: 2020-11-11 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.74 Å) Cite: EPB41L3 PanDDA analysis group deposition To Be Published
5RYP	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z1929757385 Descriptor: (3S)-1-(3-fluoropyridin-2-yl)-4,4-dimethylpyrrolidin-3-ol, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... Authors: Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2020-10-30 Release date: 2020-11-11 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.63 Å) Cite: EPB41L3 PanDDA analysis group deposition To Be Published
5RZ1	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z27682767 Descriptor: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Isoform 2 of Band 4.1-like protein 3, ... Authors: Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2020-10-30 Release date: 2020-11-11 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.62 Å) Cite: EPB41L3 PanDDA analysis group deposition To Be Published
5RZJ	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z2856434938 Descriptor: 1,2-ETHANEDIOL, 1-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-methanamine, DIMETHYL SULFOXIDE, ... Authors: Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2020-10-30 Release date: 2020-11-11 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.68 Å) Cite: EPB41L3 PanDDA analysis group deposition To Be Published
5RZZ	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z1551999220 Descriptor: (2R)-3-(4-bromophenyl)-2-methylpropanamide, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... Authors: Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2020-10-30 Release date: 2020-11-11 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.76 Å) Cite: EPB41L3 PanDDA analysis group deposition To Be Published
5RZ7	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z57472297 Descriptor: 1,2-ETHANEDIOL, 1-[2-methyl-1,3-bis(oxidanyl)propan-2-yl]-3-phenyl-urea, DIMETHYL SULFOXIDE, ... Authors: Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2020-10-30 Release date: 2020-11-11 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.76 Å) Cite: EPB41L3 PanDDA analysis group deposition To Be Published
5RZQ	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z100642432 Descriptor: 1,2-ETHANEDIOL, 2-bromo-4-fluoro-N,N-dimethylbenzamide, DIMETHYL SULFOXIDE, ... Authors: Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2020-10-30 Release date: 2020-11-11 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.88 Å) Cite: EPB41L3 PanDDA analysis group deposition To Be Published
5RYM	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z31217395 Descriptor: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Isoform 2 of Band 4.1-like protein 3, ... Authors: Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2020-10-30 Release date: 2020-11-11 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.64 Å) Cite: EPB41L3 PanDDA analysis group deposition To Be Published
5RYY	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z57257264 Descriptor: 1,2-ETHANEDIOL, 1-(3-phenylprop-2-yn-1-yl)piperidine, DIMETHYL SULFOXIDE, ... Authors: Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2020-10-30 Release date: 2020-11-11 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.69 Å) Cite: EPB41L3 PanDDA analysis group deposition To Be Published
5RZF	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z57040482 Descriptor: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Isoform 2 of Band 4.1-like protein 3, ... Authors: Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2020-10-30 Release date: 2020-11-11 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.76 Å) Cite: EPB41L3 PanDDA analysis group deposition To Be Published
5RZU	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z32400357 Descriptor: 1,2-ETHANEDIOL, 1-(3-methylbenzene-1-carbonyl)piperidine-4-carboxamide, DIMETHYL SULFOXIDE, ... Authors: Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2020-10-30 Release date: 2020-11-11 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.66 Å) Cite: EPB41L3 PanDDA analysis group deposition To Be Published
5RZB	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z271004858 Descriptor: 1,2-ETHANEDIOL, 4-amino-N-(pyridin-2-yl)benzenesulfonamide, DIMETHYL SULFOXIDE, ... Authors: Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2020-10-30 Release date: 2020-11-11 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.59 Å) Cite: EPB41L3 PanDDA analysis group deposition To Be Published
5RZR	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z53825177 Descriptor: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Isoform 2 of Band 4.1-like protein 3, ... Authors: Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2020-10-30 Release date: 2020-11-11 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.78 Å) Cite: EPB41L3 PanDDA analysis group deposition To Be Published
6T36	Crystal structure of the PTPN3 PDZ domain bound to the HBV core protein C-terminal peptide Descriptor: BROMIDE ION, Capsid protein, Tyrosine-protein phosphatase non-receptor type 3 Authors: Genera, M, Mechaly, A, Haouz, A, Caillet-Saguy, C. Deposit date: 2019-10-10 Release date: 2021-01-20 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Molecular basis of the interaction of the human tyrosine phosphatase PTPN3 with the hepatitis B virus core protein. Sci Rep, 11, 2021
5L81	Crystal structure of the PH domain of murine kindlin-3 Descriptor: Fermitin family homolog 3, SODIUM ION Authors: Ni, T, Harlos, K, Gilbert, R.J.C. Deposit date: 2016-06-06 Release date: 2017-01-11 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.23 Å) Cite: Structure and lipid-binding properties of the kindlin-3 pleckstrin homology domain. Biochem. J., 474, 2017
8GXE	PTPN21 FERM PTP complex Descriptor: CHLORIDE ION, Tyrosine-protein phosphatase non-receptor type 21 Authors: Chen, L, Zheng, Y.Y, Zhou, C. Deposit date: 2022-09-19 Release date: 2023-09-27 Last modified: 2024-04-17 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural analysis of PTPN21 reveals a dominant-negative effect of the FERM domain on its phosphatase activity. Sci Adv, 10, 2024
6OQ4	Crystal Structure of the Ternary Complex of KRIT1 bound to both the Rap1 GTPase and HKi1 Descriptor: 2-{(Z)-[(2-hydroxynaphthalen-1-yl)methylidene]amino}-N-[(1S)-1-phenylethyl]benzamide, Krev interaction trapped protein 1, MAGNESIUM ION, ... Authors: Gingras, A.R. Deposit date: 2019-04-25 Release date: 2020-06-24 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.754 Å) Cite: Inhibition of the HEG1-KRIT1 interaction increases KLF4 and KLF2 expression in endothelial cells Faseb Bioadv, 2021
4BBK	Structural and functional characterisation of the kindlin-1 pleckstrin homology domain Descriptor: FERMITIN FAMILY HOMOLOG 1, GLYCEROL Authors: Yates, L.A, Lumb, C.N, Brahme, N.N, Zalyte, R, Bird, L.E, De Colibus, L, Owens, R.J, Calderwood, D.A, Sansom, M.S.P, Gilbert, R.J.C. Deposit date: 2012-09-25 Release date: 2012-11-14 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural and Functional Characterisation of the Kindlin-1 Pleckstrin Homology Domain J.Biol.Chem., 287, 2012
6OQ3	Crystal Structure of the Ternary Complex of KRIT1 bound to both the Rap1 GTPase and HKi2 Descriptor: 2-hydroxynaphthalene-1-carbaldehyde, Krev interaction trapped protein 1, MAGNESIUM ION, ... Authors: Gingras, A.R. Deposit date: 2019-04-25 Release date: 2020-06-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Inhibition of the HEG1-KRIT1 interaction increases KLF4 and KLF2 expression in endothelial cells Faseb Bioadv, 2021
7C3M	Structure of FERM protein Descriptor: Fermitin family homolog 3,Fermitin family homolog 3,Fermitin family homolog 3 Authors: Bu, W, Loh, Z.Y, Jin, S, Basu, S, Ero, R, Park, J.E, Yan, X, Wang, M, Sze, S.K, Tan, S.M, Gao, Y.G. Deposit date: 2020-05-13 Release date: 2020-06-03 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Structural basis of human full-length kindlin-3 homotrimer in an auto-inhibited state. Plos Biol., 18, 2020

<1234567>