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1NJP
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BU of 1njp by Molmil
The crystal structure of the 50S Large ribosomal subunit from Deinococcus radiodurans complexed with a tRNA acceptor stem mimic (ASM)
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L16, GENERAL STRESS PROTEIN CTC, ...
Authors:Bashan, A, Agmon, I, Zarivatch, R, Schluenzen, F, Harms, J.M, Berisio, R, Bartels, H, Hansen, H.A, Yonath, A.
Deposit date:2003-01-02
Release date:2003-02-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis of the ribosomal machinery for Peptide bond formation, translocation, and nascent chain progression
Mol.Cell, 11, 2003
4NKT
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BU of 4nkt by Molmil
Structure of Cid1 in complex with the UTP analog UMPNPP
Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, BROMIDE ION, MAGNESIUM ION, ...
Authors:Munoz-Tello, P, Gabus, C, Thore, S.
Deposit date:2013-11-13
Release date:2013-12-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A critical switch in the enzymatic properties of the Cid1 protein deciphered from its product-bound crystal structure.
Nucleic Acids Res., 42, 2014
5E54
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BU of 5e54 by Molmil
Two apo structures of the adenine riboswitch aptamer domain determined using an X-ray free electron laser
Descriptor: MAGNESIUM ION, Vibrio vulnificus strain 93U204 chromosome II, adenine riboswitch aptamer domain
Authors:Stagno, J.R, Wang, Y.-X, Liu, Y, Bhandari, Y.R, Conrad, C.E, Nelson, G, Li, C, Wendel, D.R, White, T.A, Barty, A, Tuckey, R.A, Zatsepin, N.A, Grant, T.D, Fromme, P, Tan, K, Ji, X, Spence, J.C.H.
Deposit date:2015-10-07
Release date:2016-11-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography.
Nature, 541, 2017
3PMK
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BU of 3pmk by Molmil
Crystal structure of the Vesicular Stomatitis Virus RNA free nucleoprotein/phosphoprotein complex
Descriptor: Nucleocapsid protein, Phosphoprotein
Authors:Leyrat, C, Yabukarski, F, Tarbouriech, N, Ruigrok, R.W.H, Jamin, M.
Deposit date:2010-11-17
Release date:2011-10-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:Structure of the Vesicular Stomatitis Virus N0-P Complex
Plos Pathog., 7, 2011
2XZP
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BU of 2xzp by Molmil
Upf1 helicase
Descriptor: GLYCEROL, MALONATE ION, REGULATOR OF NONSENSE TRANSCRIPTS 1
Authors:Chakrabarti, S, Jayachandran, U, Bonneau, F, Fiorini, F, Basquin, C, Domcke, S, Le Hir, H, Conti, E.
Deposit date:2010-11-26
Release date:2011-03-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and its Regulation by Upf2.
Mol.Cell, 41, 2011
4RNE
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BU of 4rne by Molmil
Structural variations and solvent structure of UGGGGU quadruplexes stabilized by Sr2+ ions
Descriptor: CALCIUM ION, RNA (5'-R(*UP*GP*GP*GP*GP*U)-3'), SODIUM ION, ...
Authors:Fyfe, A.C, Dunten, P.W, Scott, W.G.
Deposit date:2014-10-24
Release date:2014-11-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.01 Å)
Cite:Structural Variations and Solvent Structure of r(UGGGGU) Quadruplexes Stabilized by Sr(2+) Ions.
J.Mol.Biol., 427, 2015
7D0F
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BU of 7d0f by Molmil
cryo-EM structure of a pre-catalytic group II intron RNP
Descriptor: Group II intron-encoded protein LtrA, RNA (738-MER)
Authors:Liu, N, Dong, X.L, Hu, C.X, Zeng, J.W, Wang, J.W, Wang, J, Wang, H.W, Belfort, M.
Deposit date:2020-09-10
Release date:2020-09-30
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Exon and protein positioning in a pre-catalytic group II intron RNP primed for splicing.
Nucleic Acids Res., 48, 2020
7D1A
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BU of 7d1a by Molmil
cryo-EM structure of a group II intron RNP complexed with its reverse transcriptase
Descriptor: Group II intron-encoded protein LtrA, RNA (5'-R(P*CP*AP*CP*AP*UP*CP*CP*AP*UP*AP*AP*C)-3'), RNA (692-MER)
Authors:Liu, N, Dong, X.L, Hu, C.X, Zeng, J.W, Wang, J.W, Wang, J, Wang, H.W, Belfort, M.
Deposit date:2020-09-14
Release date:2020-10-21
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Exon and protein positioning in a pre-catalytic group II intron RNP primed for splicing.
Nucleic Acids Res., 48, 2020
4G7O
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BU of 4g7o by Molmil
Crystal structure of Thermus thermophilus transcription initiation complex containing 2 nt of RNA
Descriptor: 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', 5'-R(*GP*A)-3', ...
Authors:Zhang, Y, Ebright, R.H.
Deposit date:2012-07-20
Release date:2012-10-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.993 Å)
Cite:Structural basis of transcription initiation.
Science, 338, 2012
3T72
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BU of 3t72 by Molmil
PhoB(E)-Sigma70(4)-(RNAP-Betha-flap-tip-helix)-DNA Transcription Activation Sub-Complex
Descriptor: PHO BOX DNA (STRAND 1), PHO BOX DNA (STRAND 2), Phosphate regulon transcriptional regulatory protein phoB, ...
Authors:Blanco, A.G, Canals, A, Bernues, J, Sola, M, Coll, M.
Deposit date:2011-07-29
Release date:2011-09-21
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (4.33 Å)
Cite:The structure of a transcription activation subcomplex reveals how sigma (70) is recruited to PhoB promoters.
Embo J., 30, 2011
6JIE
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BU of 6jie by Molmil
YaeO bound to Magnesium from Vibrio cholerae O395
Descriptor: MAGNESIUM ION, YaeO
Authors:Pal, K, Yadav, M, Sen, U.
Deposit date:2019-02-20
Release date:2019-12-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Vibrio cholerae YaeO is a Structural Homologue of RNA Chaperone Hfq that Inhibits Rho-dependent Transcription Termination by Dissociating its Hexameric State.
J.Mol.Biol., 431, 2019
5GNC
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BU of 5gnc by Molmil
Crystal structure of Phytophthora. sojae PSR2
Descriptor: Avh146
Authors:He, J.Q, Wu, B.X, Ma, J.B.
Deposit date:2016-07-20
Release date:2017-08-16
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural analysis ofPhytophthorasuppressor of RNA silencing 2 (PSR2) reveals a conserved modular fold contributing to virulence.
Proc. Natl. Acad. Sci. U.S.A., 2019
7Z77
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BU of 7z77 by Molmil
Crystal structure of compound 6 in complex with the bromodomain of human SMARCA2 and pVHL:ElonginC:ElonginB
Descriptor: (2~{S},4~{R})-~{N}-[(1~{S})-4-[4-(4-bromanyl-7-cyclopentyl-5-oxidanylidene-benzimidazolo[1,2-a]quinazolin-9-yl)piperidin-1-yl]-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]butyl]-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ...
Authors:Bader, G, Boettcher, J, Wolkerstorfer, B.
Deposit date:2022-03-15
Release date:2022-09-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo.
Nat Commun, 13, 2022
7Z76
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BU of 7z76 by Molmil
Crystal structure of compound 10 in complex with the bromodomain of human SMARCA2 and pVHL:ElonginC:ElonginB
Descriptor: (2~{S},4~{R})-~{N}-[(1~{R})-2-[(2~{R})-1-[4-(4-bromanyl-7-cyclopentyl-5-oxidanylidene-benzimidazolo[1,2-a]quinazolin-9-yl)piperidin-1-yl]propan-2-yl]oxy-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]-1-[(2~{S})-2-[[1-(dimethylamino)cyclopropyl]carbonylamino]-3,3-dimethyl-butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ...
Authors:Bader, G, Boettcher, J, Wolkerstorfer, B.
Deposit date:2022-03-15
Release date:2022-09-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo.
Nat Commun, 13, 2022
8UMU
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BU of 8umu by Molmil
Atomic model of the human CTF18-RFC-PCNA binary complex in the four-subunit binding state (state 3)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chromosome transmission fidelity protein 18 homolog, MAGNESIUM ION, ...
Authors:Wang, F, He, Q, Li, H.
Deposit date:2023-10-18
Release date:2024-05-08
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC.
Proc.Natl.Acad.Sci.USA, 121, 2024
1Y92
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BU of 1y92 by Molmil
Crystal structure of the P19A/N67D Variant Of Bovine seminal Ribonuclease
Descriptor: Seminal ribonuclease
Authors:Picone, D, Di Fiore, A, Ercole, C, Franzese, M, Sica, F, Tomaselli, S, Mazzarella, L.
Deposit date:2004-12-14
Release date:2004-12-28
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Role of the Hinge Loop in Domain Swapping: THE SPECIAL CASE OF BOVINE SEMINAL RIBONUCLEASE.
J.Biol.Chem., 280, 2005
1RDR
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BU of 1rdr by Molmil
POLIOVIRUS 3D POLYMERASE
Descriptor: CALCIUM ION, POLIOVIRUS 3D POLYMERASE
Authors:Hansen, J, Long, A, Schultz, S.
Deposit date:1998-04-28
Release date:1998-09-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the RNA-dependent RNA polymerase of poliovirus.
Structure, 5, 1997
1Y94
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BU of 1y94 by Molmil
Crystal structure of the G16S/N17T/P19A/S20A/N67D Variant Of Bovine seminal Ribonuclease
Descriptor: Seminal ribonuclease
Authors:Picone, D, Di Fiore, A, Ercole, C, Franzese, M, Sica, F, Tomaselli, S, Mazzarella, L.
Deposit date:2004-12-14
Release date:2004-12-28
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Role of the Hinge Loop in Domain Swapping: THE SPECIAL CASE OF BOVINE SEMINAL RIBONUCLEASE.
J.Biol.Chem., 280, 2005
4LB5
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BU of 4lb5 by Molmil
Crystal structure of PKZ Zalpha in complex with ds(CG)6 (hexagonal form)
Descriptor: 5'-D(*TP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*G)-3', ACETATE ION, Protein kinase containing Z-DNA binding domains
Authors:De Rosa, M, Zacarias, S, Athanasiadis, A.
Deposit date:2013-06-20
Release date:2013-09-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for Z-DNA binding and stabilization by the zebrafish Z-DNA dependent protein kinase PKZ.
Nucleic Acids Res., 41, 2013
7DE9
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BU of 7de9 by Molmil
crystal structure of Arabidopsis RDM15 tudor domain in complex with an H3K4me1 peptide
Descriptor: Histone H3.2, Transcriptional regulator
Authors:Song, Z, Du, J.
Deposit date:2020-11-03
Release date:2021-04-07
Last modified:2021-06-23
Method:X-RAY DIFFRACTION (1.711 Å)
Cite:A histone H3K4me1-specific binding protein is required for siRNA accumulation and DNA methylation at a subset of loci targeted by RNA-directed DNA methylation.
Nat Commun, 12, 2021
4LB6
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BU of 4lb6 by Molmil
Crystal structure of PKZ Zalpha in complex with ds(CG)6 (tetragonal form)
Descriptor: 5'-D(*TP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*G)-3', Protein kinase containing Z-DNA binding domains
Authors:De Rosa, M, Zacarias, S, Athanasiadis, A.
Deposit date:2013-06-20
Release date:2013-09-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for Z-DNA binding and stabilization by the zebrafish Z-DNA dependent protein kinase PKZ.
Nucleic Acids Res., 41, 2013
429D
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BU of 429d by Molmil
CRYSTAL STRUCTURE OF A LEADZYME; METAL BINDING AND IMPLICATIONS FOR CATALYSIS
Descriptor: MAGNESIUM ION, RNA (5'-R(*CP*GP*GP*AP*CP*CP*GP*AP*GP*CP*CP*AP*G)-3'), RNA (5'-R(*GP*CP*UP*GP*GP*GP*AP*GP*UP*CP*C)-3')
Authors:Wedekind, J.E, McKay, D.B.
Deposit date:1998-09-29
Release date:1999-03-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of a lead-dependent ribozyme revealing metal binding sites relevant to catalysis.
Nat.Struct.Biol., 6, 1999
4RKV
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BU of 4rkv by Molmil
Structural variations and solvent structure of UGGGGU quadruplexes stabilized by Sr2+ ions
Descriptor: CALCIUM ION, RNA (5'-R(*UP*GP*GP*GP*GP*U)-3'), SODIUM ION, ...
Authors:Fyfe, A.C, Dunten, P.W, Scott, W.G.
Deposit date:2014-10-14
Release date:2014-11-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (0.88 Å)
Cite:Structural Variations and Solvent Structure of r(UGGGGU) Quadruplexes Stabilized by Sr(2+) Ions.
J.Mol.Biol., 427, 2015
4ZNP
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BU of 4znp by Molmil
The structure of A pfI Riboswitch Bound to ZMP
Descriptor: AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, MAGNESIUM ION, pfI Riboswitch
Authors:Ren, A, Patel, D.J, Rajashankar, R.K.
Deposit date:2015-05-05
Release date:2015-08-26
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Global RNA Fold and Molecular Recognition for a pfl Riboswitch Bound to ZMP, a Master Regulator of One-Carbon Metabolism.
Structure, 23, 2015
7YG7
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BU of 7yg7 by Molmil
Structure of the Spring Viraemia of Carp Virus ribonucleoprotein Complex
Descriptor: Nucleoprotein, RNA (99-mer)
Authors:Liu, B, Wang, Z.X, Yang, T, Yu, D.Q, Ouyang, Q.
Deposit date:2022-07-11
Release date:2023-03-15
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of the Spring Viraemia of Carp Virus Ribonucleoprotein Complex Reveals Its Assembly Mechanism and Application in Antiviral Drug Screening.
J.Virol., 97, 2023

223790

数据于2024-08-14公开中

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