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5T2C
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BU of 5t2c by Molmil
CryoEM structure of the human ribosome at 3.6 Angstrom resolution
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Zhang, X, Lai, M, Zhou, Z.H.
Deposit date:2016-08-23
Release date:2017-01-25
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes.
Nat Commun, 7, 2016
8HK1
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BU of 8hk1 by Molmil
The cryo-EM structure of human pre-17S U2 snRNP
Descriptor: ATP-dependent RNA helicase DDX42, HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, ...
Authors:Zhang, X, Zhan, X, Shi, Y.
Deposit date:2022-11-24
Release date:2023-03-08
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly.
Nat Commun, 14, 2023
7OMG
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BU of 7omg by Molmil
Crystal structure of KOD DNA Polymerase in a ternary complex with an Uracil containing template
Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, ...
Authors:Betz, K, Kropp, H.M, Diederichs, K, Marx, A.
Deposit date:2021-05-22
Release date:2021-10-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for The Recognition of Deaminated Nucleobases by An Archaeal DNA Polymerase.
Chembiochem, 22, 2021
7OMB
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BU of 7omb by Molmil
Crystal structure of KOD DNA Polymerase in a ternary complex with a p/t duplex containing an extended 5' single stranded template overhang
Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA polymerase, ...
Authors:Betz, K, Kropp, H.M, Diederichs, K, Marx, A.
Deposit date:2021-05-21
Release date:2021-10-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structural Basis for The Recognition of Deaminated Nucleobases by An Archaeal DNA Polymerase.
Chembiochem, 22, 2021
6H4N
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BU of 6h4n by Molmil
Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein S1 - 70S Hibernating E. coli Ribosome
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S1, ...
Authors:Beckert, B, Turk, M, Czech, A, Berninghausen, O, Beckmann, R, Ignatova, Z, Plitzko, J, Wilson, N.D.
Deposit date:2018-07-22
Release date:2018-09-05
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein S1.
Nat Microbiol, 3, 2018
7RDQ
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BU of 7rdq by Molmil
Cryo-EM structure of Thermus thermophilus reiterative transcription complex with 11nt oligo-G RNA
Descriptor: DNA (31-MER) nontemplate strand, DNA (31-MER) template strand, DNA-directed RNA polymerase subunit alpha, ...
Authors:Liu, Y, Ebright, R.H.
Deposit date:2021-07-10
Release date:2022-02-02
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural and mechanistic basis of reiterative transcription initiation.
Proc.Natl.Acad.Sci.USA, 119, 2022
6DV9
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BU of 6dv9 by Molmil
Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 4nt spacer
Descriptor: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Lin, W, Das, K, Feng, Y, Ebright, R.H.
Deposit date:2018-06-23
Release date:2019-02-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis of ECF-sigma-factor-dependent transcription initiation.
Nat Commun, 10, 2019
8DY7
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BU of 8dy7 by Molmil
Streptomyces venezuelae RNAP transcription open promoter complex with WhiA and WhiB transcription factors
Descriptor: DNA (71-MER), DNA (78-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Lilic, M, Campbell, E.A.
Deposit date:2022-08-03
Release date:2023-03-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DY9
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BU of 8dy9 by Molmil
Streptomyces venezuelae RNAP unconstrained open promoter complex with WhiA and WhiB transcription factors
Descriptor: DNA (38-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Lilic, M, Campbell, E.A.
Deposit date:2022-08-03
Release date:2023-03-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB.
Proc.Natl.Acad.Sci.USA, 120, 2023
6JBQ
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BU of 6jbq by Molmil
CryoEM structure of Escherichia coli sigmaE transcription initiation complex containing 5nt of RNA
Descriptor: DNA (48-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Fang, C.L, Zhang, Y.
Deposit date:2019-01-26
Release date:2019-05-29
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.02 Å)
Cite:Structures and mechanism of transcription initiation by bacterial ECF factors.
Nucleic Acids Res., 47, 2019
6JCX
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BU of 6jcx by Molmil
Mycobacterium tuberculosis transcription initiation complex with ECF sigma factor sigma H and 6nt RNA
Descriptor: DNA (5'-D(*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*GP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Li, L, Zhang, Y.
Deposit date:2019-01-30
Release date:2019-05-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.903 Å)
Cite:Structures and mechanism of transcription initiation by bacterial ECF factors.
Nucleic Acids Res., 47, 2019
5I2D
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BU of 5i2d by Molmil
Crystal structure of T. thermophilus TTHB099 class II transcription activation complex: TAP-RPo
Descriptor: DNA (72-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Feng, Y, Zhang, Y, Ebright, R.H.
Deposit date:2016-02-08
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (4.405 Å)
Cite:Structural basis of transcription activation.
Science, 352, 2016
9F6E
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BU of 9f6e by Molmil
Human DNA polymerase epsilon bound to DNA and PCNA (ajar conformation)
Descriptor: 2',3'-dideoxyadenosine triphosphate, DNA nascent strand, DNA polymerase epsilon catalytic subunit A, ...
Authors:Roske, J.J, Yeeles, J.T.P.
Deposit date:2024-05-01
Release date:2024-08-07
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon.
Nat.Struct.Mol.Biol., 2024
9F6D
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BU of 9f6d by Molmil
Human DNA polymerase epsilon bound to DNA and PCNA (open conformation)
Descriptor: 2',3'-dideoxyadenosine triphosphate, DNA nascent strand, DNA polymerase epsilon catalytic subunit A, ...
Authors:Roske, J.J, Yeeles, J.T.P.
Deposit date:2024-05-01
Release date:2024-08-07
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon.
Nat.Struct.Mol.Biol., 2024
9F6F
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BU of 9f6f by Molmil
Human DNA polymerase epsilon bound to DNA and PCNA (closed conformation)
Descriptor: 2',3'-dideoxyadenosine triphosphate, DNA nascent strand, DNA polymerase epsilon catalytic subunit A, ...
Authors:Roske, J.J, Yeeles, J.T.P.
Deposit date:2024-05-01
Release date:2024-08-07
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon.
Nat.Struct.Mol.Biol., 2024
6H58
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BU of 6h58 by Molmil
Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein S1 - Full 100S Hibernating E. coli Ribosome
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S1, ...
Authors:Beckert, B, Turk, M, Czech, A, Berninghausen, O, Beckmann, R, Ignatova, Z, Plitzko, J, Wilson, D.N.
Deposit date:2018-07-24
Release date:2018-09-05
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (7.9 Å)
Cite:Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein S1.
Nat Microbiol, 3, 2018
6W1S
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BU of 6w1s by Molmil
Atomic model of the mammalian Mediator complex
Descriptor: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ...
Authors:Zhao, H, Young, N, Asturias, F.
Deposit date:2020-03-04
Release date:2021-03-10
Method:ELECTRON MICROSCOPY (4.02 Å)
Cite:A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers.
Cell, 178, 2019
4G7O
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BU of 4g7o by Molmil
Crystal structure of Thermus thermophilus transcription initiation complex containing 2 nt of RNA
Descriptor: 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', 5'-R(*GP*A)-3', ...
Authors:Zhang, Y, Ebright, R.H.
Deposit date:2012-07-20
Release date:2012-10-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.993 Å)
Cite:Structural basis of transcription initiation.
Science, 338, 2012
4XJN
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BU of 4xjn by Molmil
Structure of the parainfluenza virus 5 nucleocapsid-RNA complex: an insight into paramyxovirus polymerase activity
Descriptor: LEAD (II) ION, Nucleocapsid, RNA (78-MER)
Authors:Alayyoubi, M, Leser, G.P, Kors, C.A, Lamb, R.A.
Deposit date:2015-01-08
Release date:2015-03-18
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Structure of the paramyxovirus parainfluenza virus 5 nucleoprotein-RNA complex.
Proc.Natl.Acad.Sci.USA, 112, 2015
9F6J
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BU of 9f6j by Molmil
Human DNA Polymerase epsilon bound to T-C mismatched DNA (Polymerase Arrest state)
Descriptor: DNA nascent strand, DNA polymerase epsilon catalytic subunit A, DNA template strand, ...
Authors:Roske, J.J, Yeeles, J.T.P.
Deposit date:2024-05-01
Release date:2024-08-07
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon.
Nat.Struct.Mol.Biol., 2024
7MLB
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BU of 7mlb by Molmil
Crystal structure of Thermus thermophilus transcription initiation complex with 5nt RNA
Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*AP*GP*GP*GP*AP*TP*GP*CP*AP*G)-3'), DNA (5'-D(P*CP*TP*GP*CP*AP*TP*CP*CP*CP*TP*GP*AP*GP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Liu, Y, Ebright, R.H.
Deposit date:2021-04-28
Release date:2022-02-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural and mechanistic basis of reiterative transcription initiation.
Proc.Natl.Acad.Sci.USA, 119, 2022
8PMP
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BU of 8pmp by Molmil
Structure of the human nuclear cap-binding complex bound to ARS2[147-871] and m7GTP
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ...
Authors:Dubiez, E, Pellegrini, E, Foucher, A.E, Cusack, S, Kadlec, J.
Deposit date:2023-06-29
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex.
Cell Rep, 43, 2024
9F6L
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BU of 9f6l by Molmil
Human DNA Polymerase epsilon bound to T-C mismatched DNA (Mismatch Excision state)
Descriptor: CALCIUM ION, DNA nascent strand, DNA polymerase epsilon catalytic subunit A, ...
Authors:Roske, J.J, Yeeles, J.T.P.
Deposit date:2024-05-01
Release date:2024-08-07
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon.
Nat.Struct.Mol.Biol., 2024
9F6K
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BU of 9f6k by Molmil
Human DNA Polymerase epsilon bound to T-C mismatched DNA (Frayed Substrate state)
Descriptor: DNA nascent strand, DNA polymerase epsilon catalytic subunit A, DNA template strand, ...
Authors:Roske, J.J, Yeeles, J.T.P.
Deposit date:2024-05-01
Release date:2024-08-07
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon.
Nat.Struct.Mol.Biol., 2024
9F6I
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BU of 9f6i by Molmil
Human DNA Polymerase epsilon bound to T-C mismatched DNA (Post-Insertion state)
Descriptor: 2',3'-dideoxyadenosine triphosphate, CALCIUM ION, DNA nascent strand, ...
Authors:Roske, J.J, Yeeles, J.T.P.
Deposit date:2024-05-01
Release date:2024-08-07
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon.
Nat.Struct.Mol.Biol., 2024

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数据于2024-10-09公开中

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