4CTV
 
 | | Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-amino-2-(6-(2-(6-amino-4-methylpyridin-2-yl)ethyl) pyridin-2-yl)propyl)-4-methylpyridin-2-amine | | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, 6-(3-amino-2-(6-(2-(6-amino-4-methylpyridin-2-yl)ethyl)pyridin-2-yl)propyl)-4-methylpyridin-2-amine, ACETATE ION, ... | | Authors: | Li, H, Poulos, T.L. | | Deposit date: | 2014-03-15 | | Release date: | 2014-05-07 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Nitric Oxide Synthase Inhibitors that Interact with Both a Heme Propionate and Tetrahydrobiopterin Show High Isoform Selectivity.
J.Med.Chem., 57, 2014
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8FSP
 | | Full-length mouse 5-HT3A receptor in complex with SMP100, open-like | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-[(1R,3S,4R)-1-azabicyclo[2.2.2]octan-3-yl]-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indazol-6-one, 5-hydroxytryptamine receptor 3A | | Authors: | Felt, K.C, Chakrapani, S. | | Deposit date: | 2023-01-10 | | Release date: | 2023-12-27 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.79 Å) | | Cite: | Structural basis for partial agonism in 5-HT 3A receptors.
Nat.Struct.Mol.Biol., 31, 2024
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6SO7
 | | BamABCDE in MSP1D1 nanodisc ensemble 1-2 | | Descriptor: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | | Authors: | Iadanza, M.G, Ranson, N.A, Radford, S.E, Higgins, A.J, Calabrese, A.N, Schiffrin, B, White, P. | | Deposit date: | 2019-08-29 | | Release date: | 2021-03-31 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (10.5 Å) | | Cite: | BamABCDE in MSP1D1 nanodisc ensemble 1-2
To Be Published
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4CWY
 | | Structure of bovine endothelial nitric oxide synthase heme domain in complex with 6-(5-(((3R,4R)-4-((6-AMINO-4-METHYLPYRIDIN-2-YL)METHYL) PYRROLIDIN-3-YL)OXY)PENTYL)-4-METHYLPYRIDIN-2-AMINE | | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, 6-[5-({(3R,4R)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}oxy)pentyl]-4-methylpyridin-2-amine, ACETATE ION, ... | | Authors: | Li, H, Poulos, T.L. | | Deposit date: | 2014-04-03 | | Release date: | 2014-08-13 | | Last modified: | 2014-09-03 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Mobility of a Conserved Tyrosine Residue Controls Isoform-Dependent Enzyme-Inhibitor Interactions in Nitric Oxide Synthases.
Biochemistry, 53, 2014
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5YQ1
 | | Crystal structure of E.coli aminopeptidase N in complex with O-Methyl-L-tyrosine | | Descriptor: | Aminopeptidase N, GLYCEROL, MALONATE ION, ... | | Authors: | Marapaka, A.K, Ganji, R.J, Reddi, R, Addlagatta, A. | | Deposit date: | 2017-11-04 | | Release date: | 2018-11-07 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Crystal structure of E.coli aminopeptidase N in complex with O-Methyl-L-tyrosine
To Be Published
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6SN0
 | | BamABCDE in MSP1D1 nanodisc ensemble 0-1 | | Descriptor: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | | Authors: | Iadanza, M.G, Ranson, N.A, Radford, S.E, Higgins, A.J, Calabrese, A.N, Schiffrin, B, White, P. | | Deposit date: | 2019-08-23 | | Release date: | 2021-03-31 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (10.8 Å) | | Cite: | BamABCDE in MSP1D1 nanodisc ensemble 0-1
To Be Published
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3II0
 | | Crystal structure of human Glutamate oxaloacetate transaminase 1 (GOT1) | | Descriptor: | 1,2-ETHANEDIOL, Aspartate aminotransferase, cytoplasmic, ... | | Authors: | Ugochukwu, E, Pilka, E, Cooper, C, Bray, J.E, Yue, W.W, Muniz, J, Chaikuad, A, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Kavanagh, K.L, Oppermann, U, Structural Genomics Consortium (SGC) | | Deposit date: | 2009-07-31 | | Release date: | 2009-08-11 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Crystal structure of human Glutamate oxaloacetate transaminase 1 (GOT1)
To be Published
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3MEE
 | | HIV-1 Reverse Transcriptase in Complex with TMC278 | | Descriptor: | 4-{[4-({4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile, SULFATE ION, p51 Reverse transcriptase, ... | | Authors: | Lansdon, E.B. | | Deposit date: | 2010-03-31 | | Release date: | 2010-05-12 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal Structures of HIV-1 Reverse Transcriptase with Etravirine (TMC125) and Rilpivirine (TMC278): Implications for Drug Design.
J.Med.Chem., 53, 2010
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6SOG
 | | BamABCDE in MSP1D1 nanodisc ensemble 1-6 | | Descriptor: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | | Authors: | Iadanza, M.G, Ranson, N.A, Radford, S.E, Higgins, A.J, Calabrese, A.N, Schiffrin, B, White, P. | | Deposit date: | 2019-08-29 | | Release date: | 2021-03-31 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (8.3 Å) | | Cite: | BamABCDE in MSP1D1 nanodisc ensemble 1-6
To Be Published
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4D7O
 | | Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(4-(((3-Fluorophenethyl)amino)methyl)phenyl)-4- methylpyridin-2-amine | | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, 6-[4-({[2-(3-fluorophenyl)ethyl]amino}methyl)phenyl]-4-methylpyridin-2-amine, ACETATE ION, ... | | Authors: | Li, H, Poulos, T.L. | | Deposit date: | 2014-11-25 | | Release date: | 2015-07-01 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Nitric Oxide Synthase as a Target for Methicillin-Resistant Staphylococcus Aureus
Chem.Biol., 22, 2015
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3IJ4
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6SN8
 | | BamABCDE in MSP1D1 nanodisc ensemble 0-7 | | Descriptor: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | | Authors: | Iadanza, M.G, Ranson, N.A, Radford, S.E, Higgins, A.J, Calabrese, A.N, Schiffrin, B, White, P. | | Deposit date: | 2019-08-23 | | Release date: | 2021-03-31 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (8.4 Å) | | Cite: | BamABCDE in MSP1D1 nanodisc ensemble 0-7
To Be Published
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6SOH
 | | BamABCDE in MSP1D1 nanodisc ensemble 1-7 | | Descriptor: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | | Authors: | Iadanza, M.G, Ranson, N.A, Radford, S.E, Higgins, A.J, Calabrese, A.N, Schiffrin, B, White, P. | | Deposit date: | 2019-08-29 | | Release date: | 2021-03-31 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (9.5 Å) | | Cite: | BamABCDE in MSP1D1 nanodisc ensemble 1-7
To Be Published
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6SN3
 | | BamABCDE in MSP1D1 nanodisc ensemble 0-3 | | Descriptor: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | | Authors: | Iadanza, M.G, Ranson, N.A, Radford, S.E, Higgins, A.J, Calabrese, A.N, Schiffrin, B, White, P. | | Deposit date: | 2019-08-23 | | Release date: | 2021-03-31 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (8.4 Å) | | Cite: | BamABCDE in MSP1D1 nanodisc ensemble 0-3
To Be Published
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4CX3
 | | Structure of rat neuronal nitric oxide synthase M336V D597N mutant heme domain in complex with 4-METHYL-6-(((3R,4R)-4-((5-(PYRIDIN-2-YL) PENTYL)OXY)PYRROLIDIN-3-YL)METHYL)PYRIDIN-2-AMINE | | Descriptor: | 4-methyl-6-{[(3R,4R)-4-{[5-(pyridin-2-yl)pentyl]oxy}pyrrolidin-3-yl]methyl}pyridin-2-amine, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ... | | Authors: | Li, H, Poulos, T.L. | | Deposit date: | 2014-04-03 | | Release date: | 2014-08-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Mobility of a Conserved Tyrosine Residue Controls Isoform-Dependent Enzyme-Inhibitor Interactions in Nitric Oxide Synthases.
Biochemistry, 53, 2014
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3PIO
 | | Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit | | Descriptor: | 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | Authors: | Belousoff, M.J, Shapira, T, Bashan, A, Zimmerman, E, Arakawa, K, Kinashi, H, Rozenberg, H, Yonath, A. | | Deposit date: | 2010-11-07 | | Release date: | 2011-02-23 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.2473 Å) | | Cite: | Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit.
Proc.Natl.Acad.Sci.USA, 108, 2011
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6SN2
 | | BamABCDE in MSP1D1 nanodisc ensemble 0-2 | | Descriptor: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | | Authors: | Iadanza, M.G, Ranson, N.A, Radford, S.E, Higgins, A.J, Calabrese, A.N, Schiffrin, B, White, P. | | Deposit date: | 2019-08-23 | | Release date: | 2021-03-31 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (9.5 Å) | | Cite: | BamABCDE in MSP1D1 nanodisc ensemble 0-2
To Be Published
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5YTT
 | | Crystal structure of YB1 cold-shock domain in complex with UCAUGU | | Descriptor: | Nuclease-sensitive element-binding protein 1, RNA (5'-R(P*UP*CP*AP*UP*GP*U)-3'), SULFATE ION | | Authors: | Yang, X, Huang, Y. | | Deposit date: | 2017-11-20 | | Release date: | 2018-12-05 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal structure of a Y-box binding protein 1 (YB-1)-RNA complex reveals key features and residues interacting with RNA.
J.Biol.Chem., 294, 2019
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6SN5
 | | BamABCDE in MSP1D1 nanodisc ensemble 0-5 | | Descriptor: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | | Authors: | Iadanza, M.G, Ranson, N.A, Radford, S.E, Higgins, A.J, Calabrese, A.N, Schiffrin, B, White, P. | | Deposit date: | 2019-08-23 | | Release date: | 2021-03-31 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (9.8 Å) | | Cite: | BamABCDE in MSP1D1 nanodisc ensemble 0-5
To Be Published
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4CWV
 | | Structure of bovine endothelial nitric oxide synthase heme domain in complex with 4-METHYL-6-(((3R,4R)-4-((5-(PYRIDIN-2-YL)PENTYL)OXY) PYRROLIDIN-3-YL)METHYL)PYRIDIN-2-AMINE | | Descriptor: | 4-methyl-6-{[(3R,4R)-4-{[5-(pyridin-2-yl)pentyl]oxy}pyrrolidin-3-yl]methyl}pyridin-2-amine, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ... | | Authors: | Li, H, Poulos, T.L. | | Deposit date: | 2014-04-03 | | Release date: | 2014-08-13 | | Last modified: | 2014-09-03 | | Method: | X-RAY DIFFRACTION (2.34 Å) | | Cite: | Mobility of a Conserved Tyrosine Residue Controls Isoform-Dependent Enzyme-Inhibitor Interactions in Nitric Oxide Synthases.
Biochemistry, 53, 2014
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6SO8
 | | BamABCDE in MSP1D1 nanodisc ensemble 1-3 | | Descriptor: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | | Authors: | Iadanza, M.G, Ranson, N.A, Radford, S.E, Higgins, A.J, Calabrese, A.N, Schiffrin, B, White, P. | | Deposit date: | 2019-08-29 | | Release date: | 2021-03-31 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (9.8 Å) | | Cite: | BamABCDE in MSP1D1 nanodisc ensemble 1-3
To Be Published
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6SOC
 | | BamABCDE in MSP1D1 nanodisc ensemble 1-5 | | Descriptor: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | | Authors: | Iadanza, M.G, Ranson, N.A, Radford, S.E, Higgins, A.J, Calabrese, A.N, Schiffrin, B, White, P. | | Deposit date: | 2019-08-29 | | Release date: | 2021-03-31 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (9 Å) | | Cite: | BamABCDE in MSP1D1 nanodisc ensemble 1-5
To Be Published
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6SN4
 | | BamABCDE in MSP1D1 nanodisc ensemble 0-4 | | Descriptor: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | | Authors: | Iadanza, M.G, Ranson, N.A, Radford, S.E, Higgins, A.J, Calabrese, A.N, Schiffrin, B, White, P. | | Deposit date: | 2019-08-23 | | Release date: | 2021-03-31 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (9.5 Å) | | Cite: | BamABCDE in MSP1D1 nanodisc ensemble 0-4
To Be Published
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3PPF
 | | Crystal structure of the Candida albicans methionine synthase by surface entropy reduction, alanine variant without zinc | | Descriptor: | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase | | Authors: | Ubhi, D, Kavanagh, K, Monzingo, A.F, Robertus, J.D. | | Deposit date: | 2010-11-24 | | Release date: | 2011-10-12 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of Candida albicans methionine synthase determined by employing surface residue mutagenesis.
Arch.Biochem.Biophys., 513, 2011
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6SMX
 | | BamABCDE in MSP1D1 nanodisc | | Descriptor: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | | Authors: | Iadanza, M.G, Ranson, N.A, Radford, S.E, Higgins, A.J, Calabrese, A.N, Schiffrin, B, White, P. | | Deposit date: | 2019-08-23 | | Release date: | 2021-03-31 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (6.65 Å) | | Cite: | BamABCDE in MSP1D1 nanodisc
To Be Published
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