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7T18
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BU of 7t18 by Molmil
Rev1 Ternary Complex with dTTP and Ca2+
Descriptor: CALCIUM ION, DNA (5'-D(*AP*TP*CP*GP*CP*TP*AP*CP*CP*AP*CP*AP*CP*CP*CP*C)-3'), DNA (5'-D(P*GP*GP*GP*GP*TP*GP*TP*GP*GP*TP*AP*G)-3'), ...
Authors:Freudenthal, B.D, Weaver, T.M.
Deposit date:2021-12-01
Release date:2022-05-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mechanism of nucleotide discrimination by the translesion synthesis polymerase Rev1.
Nat Commun, 13, 2022
7Q8S
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BU of 7q8s by Molmil
Leishmania major ADP-actin filament decorated with Leishmania major cofilin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADF/Cofilin, Actin, ...
Authors:Kotila, T, Muniyandi, S, Lappalainen, P, Huiskonen, J.T.
Deposit date:2021-11-11
Release date:2022-05-18
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite.
Nat Commun, 13, 2022
7T1A
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BU of 7t1a by Molmil
Rev1 Ternary Complex with dATP and Ca2+
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*TP*CP*GP*CP*TP*AP*CP*CP*AP*CP*AP*CP*CP*CP*C)-3'), ...
Authors:Freudenthal, B.D, Weaver, T.M.
Deposit date:2021-12-01
Release date:2022-05-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Mechanism of nucleotide discrimination by the translesion synthesis polymerase Rev1.
Nat Commun, 13, 2022
6KW4
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BU of 6kw4 by Molmil
The ClassB RSC-Nucleosome Complex
Descriptor: Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ...
Authors:Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C.
Deposit date:2019-09-06
Release date:2019-11-13
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (7.55 Å)
Cite:Structure of the RSC complex bound to the nucleosome.
Science, 366, 2019
7W0E
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BU of 7w0e by Molmil
dmDicer2-LoqsPD-dsRNA Active-dicing status
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Dicer-2, isoform A, ...
Authors:Su, S, Wang, J, Wang, H.W, Ma, J.
Deposit date:2021-11-18
Release date:2022-04-27
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4.03 Å)
Cite:Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
7W0B
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BU of 7w0b by Molmil
Dicer2-LoqsPD complex at apo status
Descriptor: Dicer-2, isoform A, Loquacious, ...
Authors:Su, S, Wang, J, Wang, H.W, Ma, J.
Deposit date:2021-11-18
Release date:2022-04-27
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
7W0A
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BU of 7w0a by Molmil
dmDicer2-LoqsPD-dsRNA Dimer status
Descriptor: Dicer-2, isoform A, Loquacious, ...
Authors:Su, S, Wang, J, Wang, H.W, Ma, J.
Deposit date:2021-11-18
Release date:2022-04-27
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
1PHH
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BU of 1phh by Molmil
CRYSTAL STRUCTURE OF P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH ITS REACTION PRODUCT 3,4-DIHYDROXYBENZOATE
Descriptor: 3,4-DIHYDROXYBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE
Authors:Schreuder, H.A, Drenth, J.
Deposit date:1987-11-04
Release date:1988-04-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of p-hydroxybenzoate hydroxylase complexed with its reaction product 3,4-dihydroxybenzoate.
J.Mol.Biol., 199, 1988
7W93
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BU of 7w93 by Molmil
Crystal structure of E.coli pseudouridine kinase PsuK complexed with N1-methyl-pseudouridine
Descriptor: 5-[(2S,3R,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]-1-methyl-pyrimidine-2,4-dione, POTASSIUM ION, PfkB domain protein
Authors:Li, K.J, Li, X.J, Wu, B.X.
Deposit date:2021-12-09
Release date:2022-06-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure Characterization of Escherichia coli Pseudouridine Kinase PsuK.
Front Microbiol, 13, 2022
7SPL
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BU of 7spl by Molmil
[2T3] Self-assembling 3D DNA triangle with three inter-junction base pairs containing the L1 junction and a zero-linked center strand
Descriptor: 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, DNA (5'-D(*GP*AP*C)-3'), DNA (5'-D(*TP*CP*TP*GP*AP*TP*GP*TP*CP*C)-3'), ...
Authors:Vecchioni, S, Lu, B, Sha, R, Ohayon, Y.P, Seeman, N.C.
Deposit date:2021-11-02
Release date:2022-11-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (6.09 Å)
Cite:The Rule of Thirds: Controlling Junction Chirality and Polarity in 3D DNA Tiles.
Small, 19, 2023
5FFO
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BU of 5ffo by Molmil
Integrin alpha V beta 6 in complex with pro-TGF-beta
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Dong, X, Zhao, B, Springer, T.A.
Deposit date:2015-12-18
Release date:2017-01-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Force interacts with macromolecular structure in activation of TGF-beta.
Nature, 542, 2017
8JND
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BU of 8jnd by Molmil
The cryo-EM structure of the nonameric RAD51 ring bound to the nucleosome with the linker DNA binding
Descriptor: DNA (153-MER), DNA (156-MER), DNA repair protein RAD51 homolog 1, ...
Authors:Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H.
Deposit date:2023-06-06
Release date:2024-03-27
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site.
Nature, 628, 2024
8JNE
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BU of 8jne by Molmil
The cryo-EM structure of the decameric RAD51 ring bound to the nucleosome without the linker DNA binding
Descriptor: DNA (153-MER), DNA (156-MER), DNA repair protein RAD51 homolog 1, ...
Authors:Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H.
Deposit date:2023-06-06
Release date:2024-03-27
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.68 Å)
Cite:Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site.
Nature, 628, 2024
8JNF
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BU of 8jnf by Molmil
The cryo-EM structure of the RAD51 filament bound to the nucleosome
Descriptor: DNA (153-MER), DNA (156-MER), DNA repair protein RAD51 homolog 1, ...
Authors:Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H.
Deposit date:2023-06-06
Release date:2024-03-27
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (6.91 Å)
Cite:Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site.
Nature, 628, 2024
4YH8
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BU of 4yh8 by Molmil
Structure of yeast U2AF complex
Descriptor: Splicing factor U2AF 23 kDa subunit, Splicing factor U2AF 59 kDa subunit, ZINC ION
Authors:Yoshida, H, Park, S.Y, Urano, T, Obayashi, E.
Deposit date:2015-02-27
Release date:2015-08-12
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A novel 3' splice site recognition by the two zinc fingers in the U2AF small subunit.
Genes Dev., 29, 2015
7F9X
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BU of 7f9x by Molmil
Structure of the second OTU domain of LotA
Descriptor: LotA
Authors:Iwai, T, Takekawa, T, Kubori, T, Nagai, H, Imada, K.
Deposit date:2021-07-05
Release date:2021-10-20
Last modified:2022-02-23
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural Basis of Ubiquitin Recognition by a Bacterial Ovarian Tumor Deubiquitinase LotA.
J.Bacteriol., 204, 2022
7EQX
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BU of 7eqx by Molmil
Crystal structure of an Aedes aegypti procarboxypeptidase B1
Descriptor: Carboxypeptidase B, ZINC ION
Authors:Choong, Y.K, Gavor, E, Jobichen, C, Sivaraman, J.
Deposit date:2021-05-05
Release date:2021-11-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structure of Aedes aegypti procarboxypeptidase B1 and its binding with Dengue virus for controlling infection.
Life Sci Alliance, 5, 2022
4PI3
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BU of 4pi3 by Molmil
Crystal structure analysis of cruzain bound to vinyl sulfone analog of WRR-483 (WRR-666)
Descriptor: Cruzipain, N-[(2S)-5-(carbamimidamidooxy)-1-oxo-1-{[(1E,3S)-5-phenyl-1-(phenylsulfonyl)pent-1-en-3-yl]amino}pentan-2-yl]-4-methylpiperazine-1-carboxamide
Authors:Tochowicz, A, McKerrow, J.H.
Deposit date:2014-05-08
Release date:2014-11-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:Synthesis and Evaluation of Oxyguanidine Analogues of the Cysteine Protease Inhibitor WRR-483 against Cruzain.
Acs Med.Chem.Lett., 7, 2016
7TVD
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BU of 7tvd by Molmil
Crystal structure of the kinase domain of EGFR exon-19 (del-747-749) mutant
Descriptor: Epidermal growth factor receptor
Authors:Ashtekar, K.D, Stayrook, S.E, Lemmon, M.A.
Deposit date:2022-02-04
Release date:2022-02-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Biochemical and structural basis for differential inhibitor sensitivity of EGFR with distinct exon 19 mutations.
Nat Commun, 13, 2022
4WEV
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BU of 4wev by Molmil
Crystal structure of human AKR1B10 complexed with NADP+ and sulindac
Descriptor: Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [(1Z)-5-fluoro-2-methyl-1-{4-[methylsulfinyl]benzylidene}-1H-inden-3-yl]acetic acid
Authors:Cousido-Siah, A, Ruiz, F.X, Mitschler, A, Crespo, I, Porte, S, Pares, X, Farres, J, Podjarny, A.
Deposit date:2014-09-11
Release date:2015-01-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.453 Å)
Cite:Structural analysis of sulindac as an inhibitor of aldose reductase and AKR1B10.
Chem.Biol.Interact., 234, 2015
7WKP
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BU of 7wkp by Molmil
ICP1 Csy4
Descriptor: 3' stem loop crRNA, Csy4
Authors:Zhang, M, Peng, R.
Deposit date:2022-01-10
Release date:2023-04-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mechanistic insights into DNA binding and cleavage by a compact type I-F CRISPR-Cas system in bacteriophage.
Proc.Natl.Acad.Sci.USA, 120, 2023
7WKO
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BU of 7wko by Molmil
ICP1 Csy1-2 complex
Descriptor: Csy1, Csy2
Authors:Zhang, M, Peng, R.
Deposit date:2022-01-10
Release date:2023-04-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanistic insights into DNA binding and cleavage by a compact type I-F CRISPR-Cas system in bacteriophage.
Proc.Natl.Acad.Sci.USA, 120, 2023
7XB5
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BU of 7xb5 by Molmil
Structure of the ligand-binding domain of S. cerevisiae Upc2 in fusion with T4 lysozyme
Descriptor: fusion protein of Sterol uptake control protein 2 and Endolysin
Authors:Tan, L, Im, Y.J.
Deposit date:2022-03-20
Release date:2022-09-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.44 Å)
Cite:Structural basis for activation of fungal sterol receptor Upc2 and azole resistance.
Nat.Chem.Biol., 18, 2022
7EWF
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BU of 7ewf by Molmil
Selenomethionine-substituted structure of S. cerevisiae Csn12 in complex with Thp3 and Sem1
Descriptor: 26S proteasome complex subunit SEM1, Cop9 signalosome complex subunit 12, Protein THP3
Authors:Kuang, Z, Niu, L.
Deposit date:2021-05-25
Release date:2022-09-07
Last modified:2023-04-05
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural assembly of the nucleic-acid-binding Thp3-Csn12-Sem1 complex functioning in mRNA splicing.
Nucleic Acids Res., 50, 2022
7EWM
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BU of 7ewm by Molmil
Native crystal structure of S. cerevisiae Csn12 in complex with Thp3 and Sem1
Descriptor: 26S proteasome complex subunit SEM1, Cop9 signalosome complex subunit 12, Protein THP3
Authors:Kuang, Z, Niu, L.
Deposit date:2021-05-25
Release date:2022-09-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural assembly of the nucleic-acid-binding Thp3-Csn12-Sem1 complex functioning in mRNA splicing.
Nucleic Acids Res., 50, 2022

223790

数据于2024-08-14公开中

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