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7PDE
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BU of 7pde by Molmil
Structure of Adenylyl cyclase 9 in complex with Gs protein alpha subunit and MANT-GTP
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase 9, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
Authors:Qi, C, Korkhov, V.M.
Deposit date:2021-08-05
Release date:2022-01-19
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural basis of adenylyl cyclase 9 activation.
Nat Commun, 13, 2022
7PDF
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BU of 7pdf by Molmil
focus refinement of soluble domain of adenylyl cyclase 9 in complex with Gs protein alpha subunit and MANT-GTP
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase 9, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
Authors:Qi, C, Korkhov, V.M.
Deposit date:2021-08-05
Release date:2022-01-26
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of adenylyl cyclase 9 activation.
Nat Commun, 13, 2022
1J1C
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BU of 1j1c by Molmil
Binary complex structure of human tau protein kinase I with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Glycogen synthase kinase-3 beta, MAGNESIUM ION
Authors:Aoki, M, Yokota, T, Sugiura, I, Sasaki, C, Hasegawa, T, Okumura, C, Kohno, T, Sugio, S, Matsuzaki, T.
Deposit date:2002-12-03
Release date:2003-12-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural insight into nucleotide recognition in tau-protein kinase I/glycogen synthase kinase 3 beta.
Acta Crystallogr.,Sect.D, 60, 2004
1OHB
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BU of 1ohb by Molmil
Acetylglutamate kinase from Escherichia coli complexed with ADP and sulphate
Descriptor: ACETATE ION, ACETYLGLUTAMATE KINASE, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Gil-Ortiz, F, Ramon-Maiques, S, Fita, I, Rubio, V.
Deposit date:2003-05-23
Release date:2003-07-31
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Course of Phosphorus in the Reaction of N-Acetyl-L-Glutamate Kinase, Determined from the Structures of Crystalline Complexes, Including a Complex with an Alf(4)(-) Transition State Mimic
J.Mol.Biol., 331, 2003
1OH9
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BU of 1oh9 by Molmil
Acetylglutamate kinase from Escherichia coli complexed with MgADP, N-acetyl-L-glutamate and the transition-state mimic AlF4-
Descriptor: ACETYLGLUTAMATE KINASE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Gil-Ortiz, F, Ramon-Maiques, S, Fita, I, Rubio, V.
Deposit date:2003-05-23
Release date:2003-07-31
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:The Course of Phosphorus in the Reaction of N-Acetyl-L-Glutamate Kinase, Determined from the Structures of Crystalline Complexes, Including a Complex with an Alf(4)(-) Transition State Mimic
J.Mol.Biol., 331, 2003
1II7
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BU of 1ii7 by Molmil
Crystal structure of P. furiosus Mre11 with manganese and dAMP
Descriptor: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, Mre11 nuclease, ...
Authors:Hopfner, K.-P, Karcher, A, Craig, L, Woo, T.T, Carney, J.P, Tainer, J.A.
Deposit date:2001-04-20
Release date:2001-05-30
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase.
Cell(Cambridge,Mass.), 105, 2001
6VNW
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BU of 6vnw by Molmil
Cryo-EM structure of apo-BBSome
Descriptor: BBS1 domain-containing protein, Bardet-Biedl syndrome 18 protein, Bardet-Biedl syndrome 2 protein homolog, ...
Authors:Yang, S, Walz, T, Nachury, M, Chou, H.
Deposit date:2020-01-29
Release date:2020-07-01
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.44 Å)
Cite:Near-atomic structures of the BBSome reveal the basis for BBSome activation and binding to GPCR cargoes.
Elife, 9, 2020
8UQE
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BU of 8uqe by Molmil
Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 26-residue linker (RING not modeled in density)
Descriptor: E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E
Authors:Hu, Q, Botuyan, M.V, Mer, G.
Deposit date:2023-10-23
Release date:2024-01-17
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.562 Å)
Cite:Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8UQA
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BU of 8uqa by Molmil
Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 12-residue linker
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, SODIUM ION, ...
Authors:Hu, Q, Botuyan, M.V, Mer, G.
Deposit date:2023-10-23
Release date:2024-01-17
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.049 Å)
Cite:Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8UQB
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BU of 8uqb by Molmil
Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 20-residue linker (crystallization condition 1)
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, ZINC ION
Authors:Hu, Q, Botuyan, M.V, Mer, G.
Deposit date:2023-10-23
Release date:2024-01-17
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.484 Å)
Cite:Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8UQ9
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BU of 8uq9 by Molmil
Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 4-residue linker
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, GLYCEROL, ...
Authors:Hu, Q, Botuyan, M.V, Mer, G.
Deposit date:2023-10-23
Release date:2024-01-17
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
5K32
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BU of 5k32 by Molmil
PDE4D crystal structure in complex with small molecule inhibitor
Descriptor: 1,2-ETHANEDIOL, 4-[(3-methoxyphenyl)amino]-2-phenyl-7,8-dihydro-1,6-naphthyridin-5(6H)-one, MAGNESIUM ION, ...
Authors:Segarra, V, Hernandez, B, Roberts, R, Gracia, J, Soler, M, Bonin, I, Aymami, J.
Deposit date:2016-05-19
Release date:2017-03-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:4-Amino-7,8-dihydro-1,6-naphthyridin-5(6 H)-ones as Inhaled Phosphodiesterase Type 4 (PDE4) Inhibitors: Structural Biology and Structure-Activity Relationships.
J. Med. Chem., 61, 2018
3FFA
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BU of 3ffa by Molmil
Crystal Structure of a fast activating G protein mutant
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Guanine nucleotide-binding protein G(i), alpha-1 subunit, ...
Authors:Chauhan, R, Kapoor, N.
Deposit date:2008-12-02
Release date:2009-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural evidence for a sequential release mechanism for activation of heterotrimeric g proteins.
J.Mol.Biol., 393, 2009
6VOA
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BU of 6voa by Molmil
Cryo-EM structure of the BBSome-ARL6 complex
Descriptor: ADP-ribosylation factor-like protein 6, BBS1 domain-containing protein, Bardet-Biedl syndrome 18 protein, ...
Authors:Yang, S, Walz, T, Nachury, M.V.
Deposit date:2020-01-30
Release date:2020-06-24
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Near-atomic structures of the BBSome reveal the basis for BBSome activation and binding to GPCR cargoes.
Elife, 9, 2020
8F56
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BU of 8f56 by Molmil
Dimer of aminoglycoside efflux pump AcrD treated with gentamicin
Descriptor: Efflux pump membrane transporter
Authors:Zhang, Z.
Deposit date:2022-11-11
Release date:2022-12-28
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Cryo-EM Structures of AcrD Illuminate a Mechanism for Capturing Aminoglycosides from Its Central Cavity.
Mbio, 14, 2023
8F4N
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BU of 8f4n by Molmil
Dimer of aminoglycoside efflux pump AcrD
Descriptor: Efflux pump membrane transporter
Authors:Zhang, Z.
Deposit date:2022-11-11
Release date:2022-12-28
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Cryo-EM Structures of AcrD Illuminate a Mechanism for Capturing Aminoglycosides from Its Central Cavity.
Mbio, 14, 2023
8F3E
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BU of 8f3e by Molmil
Trimer of aminoglycoside efflux pump AcrD
Descriptor: Efflux pump membrane transporter
Authors:Zhang, Z.
Deposit date:2022-11-10
Release date:2022-12-28
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Cryo-EM Structures of AcrD Illuminate a Mechanism for Capturing Aminoglycosides from Its Central Cavity.
Mbio, 14, 2023
6LK8
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BU of 6lk8 by Molmil
Structure of Xenopus laevis Cytoplasmic Ring subunit.
Descriptor: GATOR complex protein SEC13, MGC154553 protein, MGC83295 protein, ...
Authors:Shi, Y, Huang, G, Yan, C, Zhang, Y.
Deposit date:2019-12-18
Release date:2021-07-21
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex by cryo-electron microscopy single particle analysis.
Cell Res., 30, 2020
3A1C
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BU of 3a1c by Molmil
crystal structure of the P- and N-domains of CopA, a copper-transporting P-type ATPase, bound with AMPPCP-Mg
Descriptor: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Probable copper-exporting P-type ATPase A
Authors:Tsuda, T, Toyoshima, C.
Deposit date:2009-03-31
Release date:2009-07-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Nucleotide recognition by CopA, a Cu+-transporting P-type ATPase.
Embo J., 28, 2009
4NAB
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BU of 4nab by Molmil
Structure of the (SR)Ca2+-ATPase mutant E309Q in the Ca2-E1-MgAMPPCP form
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, POTASSIUM ION, ...
Authors:Bublitz, M, Clausen, J.D, Arnou, B, Montigny, C, Jaxel, C, Nissen, P, Moller, J.V, Andersen, J.P, le Maire, M.
Deposit date:2013-10-22
Release date:2013-12-18
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:SERCA mutant E309Q binds two Ca(2+) ions but adopts a catalytically incompetent conformation.
Embo J., 32, 2013
8F2K
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BU of 8f2k by Molmil
Structure of yeast F1-ATPase determined with 100 micromolar cruentaren A
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit alpha, ATP synthase subunit beta, ...
Authors:Guo, H, Rubinstein, J.L.
Deposit date:2022-11-08
Release date:2023-04-05
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:CryoEM Structure with ATP Synthase Enables Late-Stage Diversification of Cruentaren A.
Chemistry, 29, 2023
6Z9P
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BU of 6z9p by Molmil
Transcription termination intermediate complex 1
Descriptor: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Said, N, Hilal, T, Loll, B, Wahl, M.C.
Deposit date:2020-06-04
Release date:2020-11-04
Last modified:2021-02-03
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase rho.
Science, 371, 2021
6Z8F
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BU of 6z8f by Molmil
Human Picobirnavirus D45-CP VLP
Descriptor: Capsid protein precursor
Authors:Ortega-Esteban, A, Mata, C.P, Rodriguez-Espinosa, M.J, Luque, D, Irigoyen, N, Rodriguez, J.M, de Pablo, P.J, Caston, J.R.
Deposit date:2020-06-02
Release date:2020-09-16
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-electron Microscopy Structure, Assembly, and Mechanics Show Morphogenesis and Evolution of Human Picobirnavirus.
J.Virol., 94, 2020
7JY7
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BU of 7jy7 by Molmil
Structure of a 12 base pair RecA-D loop complex
Descriptor: DNA (27-MER), DNA (48-MER), MAGNESIUM ION, ...
Authors:Pavletich, N.P.
Deposit date:2020-08-29
Release date:2020-11-04
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Mechanism of strand exchange from RecA-DNA synaptic and D-loop structures.
Nature, 586, 2020
6Z8D
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BU of 6z8d by Molmil
Human Picobirnavirus CP VLP
Descriptor: Capsid protein precursor
Authors:Ortega-Esteban, A, Mata, C.P, Rodriguez-Espinosa, M.J, Luque, D, Irigoyen, N, Rodriguez, J.M, de Pablo, P.J, Caston, J.R.
Deposit date:2020-06-02
Release date:2020-09-23
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.63 Å)
Cite:Cryo-electron Microscopy Structure, Assembly, and Mechanics Show Morphogenesis and Evolution of Human Picobirnavirus.
J.Virol., 94, 2020

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数据于2024-10-09公开中

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