PDB: 19260 resultsInfo pagesStatus searchChemie searchBIRD

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3G61	Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding Descriptor: (4S,11S,18S)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, Multidrug resistance protein 1a Authors: Aller, S.G, Yu, J, Ward, A, Weng, Y, Chittaboina, S, Zhuo, R, Harrell, P.M, Trinh, Y.T, Zhang, Q, Urbatsch, I.L, Chang, G. Deposit date: 2009-02-05 Release date: 2009-03-24 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (4.35 Å) Cite: Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Science, 323, 2009
3G33	Crystal structure of CDK4/cyclin D3 Descriptor: CCND3 protein, Cell division protein kinase 4 Authors: Takaki, T, Echalier, A, Brown, N.R, Hunt, T, Endicott, J.A, Noble, M.E.M. Deposit date: 2009-02-01 Release date: 2009-03-10 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3 Å) Cite: The structure of CDK4/cyclin D3 has implications for models of CDK activation. Proc.Natl.Acad.Sci.USA, 106, 2009
3G3H	Crystal structure of the GluR6 ligand binding domain dimer K665R I749L Q753K mutant with glutamate and NaCl at 1.5 Angstrom resolution Descriptor: CHLORIDE ION, GLUTAMIC ACID, Glutamate receptor, ... Authors: Chaudhry, C, Mayer, M.L. Deposit date: 2009-02-02 Release date: 2009-06-02 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Stability of ligand-binding domain dimer assembly controls kainate receptor desensitization. Embo J., 28, 2009
3G4M	Crystal structure of guanine riboswitch bound to 2-aminopurine Descriptor: 9H-purin-2-amine, ACETATE ION, COBALT HEXAMMINE(III), ... Authors: Gilbert, S.D, Batey, R.T. Deposit date: 2009-02-04 Release date: 2009-06-23 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Adaptive ligand binding by the purine riboswitch in the recognition of Guanine and adenine analogs. Structure, 17, 2009
3G3K	Crystal structure of the GluR6 ligand binding domain dimer I442H K494E K665R I749L Q753K E757Q mutant with glutamate and NaCl at 1.24 Angstrom resolution Descriptor: CHLORIDE ION, GLUTAMIC ACID, Glutamate receptor, ... Authors: Chaudhry, C, Mayer, M.L. Deposit date: 2009-02-02 Release date: 2009-06-02 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (1.24 Å) Cite: Stability of ligand-binding domain dimer assembly controls kainate receptor desensitization. Embo J., 28, 2009
3G51	Structural diversity of the active conformation of the N-terminal kinase domain of p90 ribosomal S6 kinase 2 Descriptor: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribosomal protein S6 kinase alpha-3 Authors: Kurinov, I. Deposit date: 2009-02-04 Release date: 2009-12-15 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural diversity of the active N-terminal kinase domain of p90 ribosomal S6 kinase 2 Plos One, 4, 2009
3FXZ	Crystal structure of PAK1 kinase domain with ruthenium complex lambda-FL172 Descriptor: OCTAHEDRAL RU-PYRIDOCARBAZOLE, Serine/threonine-protein kinase PAK 1 Authors: Maksimoska, J, Marmorstein, R, Meggers, E. Deposit date: 2009-01-21 Release date: 2009-02-17 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Targeting Large Kinase Active Site with Rigid, Bulky Octahedral Ruthenium Complexes J.Am.Chem.Soc., 130, 2008
3G3J	Crystal structure of the GluR6 ligand binding domain dimer I442H K494E K665R I749L Q753K mutant with glutamate and NaCl at 1.32 Angstrom resolution Descriptor: CHLORIDE ION, GLUTAMIC ACID, Glutamate receptor, ... Authors: Chaudhry, C, Mayer, M.L. Deposit date: 2009-02-02 Release date: 2009-06-02 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (1.321 Å) Cite: Stability of ligand-binding domain dimer assembly controls kainate receptor desensitization. Embo J., 28, 2009
3HLO	Crystal structure of chemically synthesized 'covalent dimer' [Gly51/D-Ala51']HIV-1 protease Descriptor: 'covalent dimer' [Gly51/D-Ala51'] HIV-1 protease, N-{(2S)-2-[(N-acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-N~5~-[amino(iminio)methyl]-L-ornithinamide Authors: Torbeev, V.Y, Kent, S.B.H. Deposit date: 2009-05-27 Release date: 2011-07-27 Last modified: 2012-12-12 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Protein conformational dynamics in the mechanism of HIV-1 protease catalysis. Proc.Natl.Acad.Sci.USA, 108, 2011
3FIE	Crystal structure of Clostridium botulinum neurotoxin serotype F catalytic domain with an inhibitor (inh1) Descriptor: BOTULINUM NEUROTOXIN TYPE F, ZINC ION, fragment of Vesicle-associated membrane protein 2 Authors: Agarwal, R, Swaminathan, S. Deposit date: 2008-12-11 Release date: 2009-06-23 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Mode of VAMP substrate recognition and inhibition of Clostridium botulinum neurotoxin F. Nat.Struct.Mol.Biol., 16, 2009
3G3F	Crystal structure of the GluR6 ligand binding domain dimer with glutamate and NaCl at 1.38 Angstrom resolution Descriptor: CHLORIDE ION, GLUTAMIC ACID, Glutamate receptor, ... Authors: Chaudhry, C, Mayer, M.L. Deposit date: 2009-02-02 Release date: 2009-06-02 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.377 Å) Cite: Stability of ligand-binding domain dimer assembly controls kainate receptor desensitization. Embo J., 28, 2009
3FY0	Crystal structure of PAK1 kinase domain with ruthenium complex DW1 Descriptor: Ruthenium pyridocarbazole, Serine/threonine-protein kinase PAK 1 Authors: Maksimoska, J, Marmorstein, R, Meggers, E. Deposit date: 2009-01-21 Release date: 2009-03-03 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Targeting Large Kinase Active Site with Rigid, Bulky Octahedral Ruthenium Complexes J.Am.Chem.Soc., 130, 2008
3I6M	3D Structure of Torpedo californica acetylcholinesterase complexed with N-piperidinopropyl-galanthamine Descriptor: (4aS,6R,8aS)-3-methoxy-11-(3-piperidin-1-ylpropyl)-5,6,9,10,11,12-hexahydro-4aH-[1]benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Lamba, D, Bartolucci, C. Deposit date: 2009-07-07 Release date: 2010-01-12 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.26 Å) Cite: Probing Torpedo californica acetylcholinesterase catalytic gorge with two novel bis-functional galanthamine derivatives. J.Med.Chem., 53, 2010
3GX3	Crystal structure of the T. tengcongensis SAM-I riboswitch variant U34C/A94G bound with SAH Descriptor: MAGNESIUM ION, POTASSIUM ION, RNA (94-MER), ... Authors: Montange, R.K, Batey, R.T. Deposit date: 2009-04-01 Release date: 2010-01-12 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Discrimination between Closely Related Cellular Metabolites by the SAM-I Riboswitch. J.Mol.Biol., 396, 2010
3H5V	Crystal structure of the GluR2-ATD Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2 Authors: Jin, R, Singh, S.K, Gu, S, Furukawa, H, Sobolevsky, A, Zhou, J, Jin, Y, Gouaux, E. Deposit date: 2009-04-22 Release date: 2009-06-09 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.33 Å) Cite: Crystal structure and association behaviour of the GluR2 amino-terminal domain. Embo J., 28, 2009
3H6H	Crystal structure of the GluR6 amino terminal domain dimer assembly MPD form Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Glutamate receptor, ... Authors: Kumar, J, Mayer, M.L. Deposit date: 2009-04-23 Release date: 2009-05-26 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.901 Å) Cite: The N-terminal domain of GluR6-subtype glutamate receptor ion channels. Nat.Struct.Mol.Biol., 16, 2009
3HKL	Crystal Structure of the Frizzled-like Cysteine-rich Domain of MuSK Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Muscle, skeletal receptor tyrosine protein kinase Authors: Stiegler, A.L, Hubbard, S.R. Deposit date: 2009-05-24 Release date: 2009-08-25 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of the frizzled-like cysteine-rich domain of the receptor tyrosine kinase MuSK. J.Mol.Biol., 393, 2009
3HKB	Tubulin: RB3 Stathmin-like domain complex Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Dorleans, A, Gigant, B, Ravelli, R.B.G, Mailliet, P, Mikol, V, Knossow, M. Deposit date: 2009-05-23 Release date: 2009-09-01 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.65 Å) Cite: Variations in the colchicine-binding domain provide insight into the structural switch of tubulin Proc.Natl.Acad.Sci.USA, 106, 2009
3HDH	PIG HEART SHORT CHAIN L-3-HYDROXYACYL COA DEHYDROGENASE REVISITED: SEQUENCE ANALYSIS AND CRYSTAL STRUCTURE DETERMINATION Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PROTEIN (L-3-HYDROXYACYL COA DEHYDROGENASE) Authors: Barycki, J.J, O'Brien, L.K, Birktoft, J.J, Strauss, A.W, Banaszak, L.J. Deposit date: 1999-04-13 Release date: 1999-10-08 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Pig heart short chain L-3-hydroxyacyl-CoA dehydrogenase revisited: sequence analysis and crystal structure determination. Protein Sci., 8, 1999
3HKC	Tubulin-ABT751: RB3 stathmin-like domain complex Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Dorleans, A, Gigant, B, Ravelli, R.B.G, Mailliet, P, Mikol, V, Knossow, M. Deposit date: 2009-05-23 Release date: 2009-09-01 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.8 Å) Cite: Variations in the colchicine-binding domain provide insight into the structural switch of tubulin Proc.Natl.Acad.Sci.USA, 106, 2009
3HKE	Tubulin-T138067: RB3 stathmin-like domain complex Descriptor: 2,3,4,5,6-pentafluoro-N-(3-fluoro-4-methoxyphenyl)benzenesulfonamide, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Dorleans, A, Gigant, B, Ravelli, R.B.G, Mailliet, P, Mikol, V, Knossow, M. Deposit date: 2009-05-23 Release date: 2009-09-01 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Variations in the colchicine-binding domain provide insight into the structural switch of tubulin Proc.Natl.Acad.Sci.USA, 106, 2009
3HKD	Tubulin-TN16 : RB3 stathmin-like domain complex Descriptor: (3Z,5S)-5-benzyl-3-[1-(phenylamino)ethylidene]pyrrolidine-2,4-dione, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Dorleans, A, Gigant, B, Ravelli, R.B.G, Mailliet, P, Mikol, V, Knossow, M. Deposit date: 2009-05-23 Release date: 2009-09-01 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.7 Å) Cite: Variations in the colchicine-binding domain provide insight into the structural switch of tubulin Proc.Natl.Acad.Sci.USA, 106, 2009
3IAW	Crystal structure of a chemically synthesized 203 amino acid 'covalent dimer' [Gly51;Aib51']HIV-1 protease molecule complexed with MVT-101 reduced isostere inhibitor at 1.6 A resolution Descriptor: N-{(2S)-2-[(N-acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-N~5~-[amino(iminio)methyl]-L-ornithinamide, SULFATE ION, [Gly51;Aib51'] 'covalent dimer' HIV-1 protease Authors: Torbeev, V.Y, Kent, S.B.H. Deposit date: 2009-07-14 Release date: 2011-04-27 Last modified: 2012-12-12 Method: X-RAY DIFFRACTION (1.61 Å) Cite: Protein conformational dynamics in the mechanism of HIV-1 protease catalysis. Proc.Natl.Acad.Sci.USA, 108, 2011
3IJ7	Directed 'in situ' Elongation as a Strategy to Characterize the Covalent Glycosyl-Enzyme Catalytic Intermediate of Human Pancreatic a-Amylase Descriptor: 4-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranosyl fluoride, 4-O-methyl-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-2)-5-fluoro-alpha-L-idopyranose, CALCIUM ION, ... Authors: Li, C, Zhang, R, Withers, S.G, Brayer, G.D. Deposit date: 2009-08-03 Release date: 2009-10-27 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2 Å) Cite: Directed "in situ" inhibitor elongation as a strategy to structurally characterize the covalent glycosyl-enzyme intermediate of human pancreatic alpha-amylase Biochemistry, 48, 2009
3FII	Crystal structure of Clostridium botulinum neurotoxin serotype F catalytic domain with an inhibitor (inh2) Descriptor: BOTULINUM NEUROTOXIN TYPE F, ZINC ION, fragment of Vesicle-associated membrane protein 2 Authors: Agarwal, R, Swaminathan, S. Deposit date: 2008-12-11 Release date: 2009-06-23 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.17 Å) Cite: Mode of VAMP substrate recognition and inhibition of Clostridium botulinum neurotoxin F. Nat.Struct.Mol.Biol., 16, 2009

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