1IO0
 
 | | CRYSTAL STRUCTURE OF TROPOMODULIN C-TERMINAL HALF | | Descriptor: | TROPOMODULIN, ZINC ION | | Authors: | Krieger, I, Kostyukova, A, Yamashita, A, Maeda, Y. | | Deposit date: | 2000-12-14 | | Release date: | 2002-11-27 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Crystal structure of the C-terminal half of tropomodulin and structural basis of actin filament pointed-end capping.
Biophys.J., 83, 2002
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3VPP
 | | Crystal Structure of the Human CLEC9A C-type Lectin-Like Domain | | Descriptor: | C-type lectin domain family 9 member A, CALCIUM ION | | Authors: | Czabotar, P.E, Zhang, J.G, Policheni, A.N, Shortman, K, Lahoud, M.H, Colman, P.M. | | Deposit date: | 2012-03-07 | | Release date: | 2012-04-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.642 Å) | | Cite: | The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments.
Immunity, 36, 2012
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1WIG
 | | Solution structure of RSGI RUH-019, a LIM domain of actin binding LIM protein 2 (KIAA1808 protein) from human cDNA | | Descriptor: | KIAA1808 protein, ZINC ION | | Authors: | Abe, T, Hirota, H, Koshiba, S, Kigawa, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2004-05-28 | | Release date: | 2004-11-28 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of RSGI RUH-019, a LIM domain of actin binding LIM protein 2 (KIAA1808 protein) from human cDNA
To be Published
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4GN1
 | | Crystal Structure of the RA and PH domains of Lamellipodin | | Descriptor: | MALONATE ION, Ras-associated and pleckstrin homology domains-containing protein 1 | | Authors: | Chang, Y.C.E, Wu, J. | | Deposit date: | 2012-08-16 | | Release date: | 2012-11-28 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of Lamellipodin implicates diverse functions in actin polymerization and Ras signaling.
Protein Cell, 4, 2013
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1X3N
 | | Crystal structure of AMPPNP bound Propionate kinase (TdcD) from Salmonella typhimurium | | Descriptor: | 1,2-ETHANEDIOL, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Propionate kinase | | Authors: | Simanshu, D.K, Savithri, H.S, Murthy, M.R. | | Deposit date: | 2005-05-10 | | Release date: | 2005-09-27 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal Structures of ADP and AMPPNP-bound Propionate Kinase (TdcD) from Salmonella typhimurium: Comparison with Members of Acetate and Sugar Kinase/Heat Shock Cognate 70/Actin Superfamily.
J.Mol.Biol., 352, 2005
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8JO4
 | | Cryo-EM structure of a Legionella effector complexed with actin and ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Zhou, X.T, Wang, X.F, Tan, J.X, Zhu, Y.Q. | | Deposit date: | 2023-06-07 | | Release date: | 2024-05-01 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.04 Å) | | Cite: | Legionella effector LnaB is a phosphoryl-AMPylase that impairs phosphosignalling.
Nature, 2024
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8JO3
 | | Cryo-EM structure of a Legionella effector complexed with actin and AMP | | Descriptor: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | Authors: | Zhou, X.T, Wang, X.F, Tan, J.X, Zhu, Y.Q. | | Deposit date: | 2023-06-07 | | Release date: | 2024-05-01 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.66 Å) | | Cite: | Legionella effector LnaB is a phosphoryl-AMPylase that impairs phosphosignalling.
Nature, 2024
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6P4X
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8V2O
 | | Cryo-EM Structure of Wildtype Smooth Muscle Gamma Actin (ACTG2) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, gamma-enteric smooth muscle, ... | | Authors: | Palmer, N.J, Carman, P.J, Ceron, R.H, Dominguez, R. | | Deposit date: | 2023-11-23 | | Release date: | 2024-05-01 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.45 Å) | | Cite: | Molecular mechanisms linking missense ACTG2 mutations to visceral myopathy.
Sci Adv, 10, 2024
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8V30
 | | Smooth Muscle Gamma Actin (ACTG2) Filament Mutant R40C | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, gamma-enteric smooth muscle, ... | | Authors: | Palmer, N.J, Carman, P.J, Ceron, R.H, Dominguez, R. | | Deposit date: | 2023-11-25 | | Release date: | 2024-05-01 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.54 Å) | | Cite: | Molecular mechanisms linking missense ACTG2 mutations to visceral myopathy.
Sci Adv, 10, 2024
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6PDT
 | | cryoEM structure of yeast glucokinase filament | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Glucokinase-1, MAGNESIUM ION, ... | | Authors: | Lynch, E.M, Dosey, A.M, Farrell, D.P, Stoddard, P.R, Kollman, J.M. | | Deposit date: | 2019-06-19 | | Release date: | 2020-03-11 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Polymerization in the actin ATPase clan regulates hexokinase activity in yeast.
Science, 367, 2020
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8IAH
 | | Structure of mammalian spectrin-actin junctional complex of membrane skeleton, State I, Global map | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | | Authors: | Li, N, Chen, S, Gao, N. | | Deposit date: | 2023-02-08 | | Release date: | 2023-05-03 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural basis of membrane skeleton organization in red blood cells.
Cell, 186, 2023
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8IAI
 | | Structure of mammalian spectrin-actin junctional complex of membrane skeleton, State II, Global map | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | | Authors: | Li, N, Chen, S, Gao, N. | | Deposit date: | 2023-02-08 | | Release date: | 2023-05-03 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structural basis of membrane skeleton organization in red blood cells.
Cell, 186, 2023
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8IB2
 | | Structure of mammalian spectrin-actin junctional complex of membrane skeleton, Pointed-end segment, headpiece domain of dematin optimized | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | | Authors: | Li, N, Chen, S, Gao, N. | | Deposit date: | 2023-02-09 | | Release date: | 2023-04-26 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural basis of membrane skeleton organization in red blood cells.
Cell, 186, 2023
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8WAG
 | | Crystal structure of the C-terminal fragment (residues 716-982) of Arabidopsis thaliana CHUP1 | | Descriptor: | Protein CHUP1, chloroplastic | | Authors: | Shimada, A, Nakamura, Y, Takano, A, Kohda, D. | | Deposit date: | 2023-09-07 | | Release date: | 2024-01-17 | | Last modified: | 2024-04-10 | | Method: | X-RAY DIFFRACTION (3.003 Å) | | Cite: | CHLOROPLAST UNUSUAL POSITIONING 1 is a plant-specific actin polymerization factor regulating chloroplast movement.
Plant Cell, 36, 2024
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8WAF
 | | Crystal structure of the C-terminal fragment (residues 756-982 with the C864S mutation) of Arabidopsis thaliana CHUP1 | | Descriptor: | Protein CHUP1, chloroplastic | | Authors: | Shimada, A, Takano, A, Nakamura, Y, Kohda, D. | | Deposit date: | 2023-09-07 | | Release date: | 2024-01-17 | | Last modified: | 2024-04-10 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | CHLOROPLAST UNUSUAL POSITIONING 1 is a plant-specific actin polymerization factor regulating chloroplast movement.
Plant Cell, 36, 2024
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6W17
 | | Structure of Dip1-activated Arp2/3 complex with nucleated actin filament | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | Authors: | Shaaban, M, Nolen, B.J, Chowdhury, S. | | Deposit date: | 2020-03-03 | | Release date: | 2020-08-12 | | Last modified: | 2020-11-18 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Cryo-EM reveals the transition of Arp2/3 complex from inactive to nucleation-competent state.
Nat.Struct.Mol.Biol., 27, 2020
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7LXE
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5NW4
 | | Human cytoplasmic dynein-1 bound to dynactin and an N-terminal construct of BICD2 | | Descriptor: | Arp1, Arp11, BICD2N, ... | | Authors: | Zhang, K, Foster, H.E, Carter, A.P. | | Deposit date: | 2017-05-05 | | Release date: | 2017-08-02 | | Last modified: | 2018-11-21 | | Method: | ELECTRON MICROSCOPY (8.7 Å) | | Cite: | Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated.
Cell, 169, 2017
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7PLZ
 | | Cryo-EM structure of the actomyosin-V complex in the rigor state (central 3er/2er, young JASP-stabilized F-actin) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Pospich, S, Sweeney, H.L, Houdusse, A, Raunser, S. | | Deposit date: | 2021-09-01 | | Release date: | 2021-12-22 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism.
Elife, 10, 2021
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7PLY
 | | Cryo-EM structure of the actomyosin-V complex in the rigor state (central 1er, young JASP-stabilized F-actin) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Pospich, S, Sweeney, H.L, Houdusse, A, Raunser, S. | | Deposit date: | 2021-09-01 | | Release date: | 2021-12-22 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism.
Elife, 10, 2021
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5GTT
 | | Crystal structure of C. perfringens iota-like enterotoxin CPILE-a | | Descriptor: | 1,2-ETHANEDIOL, Binary enterotoxin of Clostridium perfringens component a | | Authors: | Toniti, W, Yoshida, T, Tsurumura, T, Irikura, D, Tsuge, H. | | Deposit date: | 2016-08-23 | | Release date: | 2017-03-01 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.011 Å) | | Cite: | Crystal structure and structure-based mutagenesis of actin-specific ADP-ribosylating toxin CPILE-a as novel enterotoxin
PLoS ONE, 12, 2017
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5H0P
 | | Crystal structure of EF-hand protein mutant | | Descriptor: | CALCIUM ION, EF-hand domain-containing protein D2 | | Authors: | Park, K.R, An, J.Y, Kang, J.Y, Lee, J.G, Youn, H.S, Lee, Y, Mun, S.A, Jun, C.D, Song, W.K, Eom, S.H. | | Deposit date: | 2016-10-06 | | Release date: | 2017-09-13 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.862 Å) | | Cite: | Structural mechanism underlying regulation of human EFhd2/Swiprosin-1 actin-bundling activity by Ser183 phosphorylation.
Biochem. Biophys. Res. Commun., 483, 2017
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7PM2
 | | Cryo-EM structure of the actomyosin-V complex in the rigor state (central 1er, young JASP-stabilized F-actin, class 4) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Pospich, S, Sweeney, H.L, Houdusse, A, Raunser, S. | | Deposit date: | 2021-09-01 | | Release date: | 2021-12-22 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism.
Elife, 10, 2021
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7PM3
 | | Cryo-EM structure of young JASP-stabilized F-actin (central 3er) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Pospich, S, Sweeney, H.L, Houdusse, A, Raunser, S. | | Deposit date: | 2021-09-01 | | Release date: | 2021-12-22 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism.
Elife, 10, 2021
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