8JO3

Cryo-EM structure of a Legionella effector complexed with actin and AMP

Summary for 8JO3

Entry DOI	10.2210/pdb8jo3/pdb
EMDB information	36454
Descriptor	Substrate of the Dot/Icm secretion system, Actin, alpha skeletal muscle, ADENOSINE MONOPHOSPHATE, ... (5 entities in total)
Functional Keywords	ampylation, toxin
Biological source	Legionella sainthelensi More
Total number of polymer chains	2
Total formula weight	93612.91
Authors	Zhou, X.T.,Wang, X.F.,Tan, J.X.,Zhu, Y.Q. (deposition date: 2023-06-07, release date: 2024-05-01, Last modification date: 2024-07-03)
Primary citation	Wang, T.,Song, X.,Tan, J.,Xian, W.,Zhou, X.,Yu, M.,Wang, X.,Xu, Y.,Wu, T.,Yuan, K.,Ran, Y.,Yang, B.,Fan, G.,Liu, X.,Zhou, Y.,Zhu, Y. Legionella effector LnaB is a phosphoryl-AMPylase that impairs phosphosignalling. Nature, 2024 Cited by PubMed: 38776962 DOI: 10.1038/s41586-024-07573-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.66 Å)

Structure validation