8JO3
Cryo-EM structure of a Legionella effector complexed with actin and AMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Substrate of the Dot/Icm secretion system | polymer | 436 | 50621.5 | 1 | UniProt (A0A2H5FI52) | Legionella sainthelensi | |
| 2 | B (B) | Actin, alpha skeletal muscle | polymer | 377 | 42097.0 | 1 | UniProt (P68135) Pfam (PF00022) | Oryctolagus cuniculus (Rabbit) | Alpha-actin-1 |
| 3 | C (A) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) | |||
| 4 | D (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | E (B) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) |
Sequence modifications
A: 1 - 425 (UniProt: A0A2H5FI52)
| PDB | External Database | Details |
|---|---|---|
| Ser 426 | - | expression tag |
| Ser 427 | - | expression tag |
| Gly 428 | - | expression tag |
| Trp 429 | - | expression tag |
| Ser 430 | - | expression tag |
| His 431 | - | expression tag |
| Pro 432 | - | expression tag |
| Gln 433 | - | expression tag |
| Phe 434 | - | expression tag |
| Glu 435 | - | expression tag |
| Lys 436 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 92718.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 894.5 | |
| All* | Total formula weight | 93612.9 |
