PDB: 123 resultsInfo pagesStatus searchChemie searchBIRD

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9GD3	Structure of a mononucleosome bound by one copy of Chd1 with the DBD on the exit-side DNA. Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromo domain-containing protein 1, ... Authors: Engeholm, M, Roske, J.J, Oberbeckmann, E, Dienemann, C, Lidschreiber, M, Cramer, P, Farnung, L. Deposit date: 2024-08-04 Release date: 2024-09-18 Last modified: 2024-10-02 Method: ELECTRON MICROSCOPY (3 Å) Cite: Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT. Mol.Cell, 84, 2024
6RYR	Nucleosome-CHD4 complex structure (single CHD4 copy) Descriptor: Chromodomain-helicase-DNA-binding protein 4,Chromodomain-helicase-DNA-binding protein 4,Chromodomain-helicase-DNA-binding protein 4, DNA (149-MER), Histone H2A type 1, ... Authors: Farnung, L, Ochmann, M, Cramer, P. Deposit date: 2019-06-11 Release date: 2020-07-15 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations. Elife, 9, 2020
6FTX	Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromatin-remodeling ATPase, ... Authors: Sundaramoorthy, R, Owen-hughes, T, Norman, D.G, Hughes, A. Deposit date: 2018-02-25 Release date: 2018-08-08 Last modified: 2024-10-09 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome. Elife, 7, 2018
8UXQ	Structure of Heterochromatin Protein 1 (HP1) alpha in complex with an H2A.Z nucleosome Descriptor: Chromobox protein homolog 5, DNA Widom601 (208bp) strand1, DNA Widom601 (208bp) strand2, ... Authors: Tan, D, Sokolova, V. Deposit date: 2023-11-09 Release date: 2024-09-25 Last modified: 2025-04-09 Method: ELECTRON MICROSCOPY (6.3 Å) Cite: Structural mechanism of HP1⍺-dependent transcriptional repression and chromatin compaction. Structure, 32, 2024
6G0L	Structure of two molecules of the chromatin remodelling enzyme Chd1 bound to a nucleosome Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromo domain-containing protein 1, ... Authors: Sundaramoorthy, R, Owen-hughes, T, Norman, D.G, Hughes, A. Deposit date: 2018-03-19 Release date: 2018-08-22 Last modified: 2024-11-13 Method: ELECTRON MICROSCOPY (10 Å) Cite: Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome. Elife, 7, 2018
7TN2	Composite model of a Chd1-nucleosome complex in the nucleotide-free state derived from 2.3A and 2.7A Cryo-EM maps Descriptor: Chromo domain-containing protein 1, DNA Lagging Strand, DNA Tracking Strand, ... Authors: Nodelman, I.M, Bowman, G.D, Armache, J.-P. Deposit date: 2022-01-20 Release date: 2022-03-02 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (2.3 Å) Cite: Nucleosome recognition and DNA distortion by the Chd1 remodeler in a nucleotide-free state. Nat.Struct.Mol.Biol., 29, 2022
6S47	Saccharomyces cerevisiae 80S ribosome bound with ABCF protein New1 Descriptor: 18S rRNA (1707-MER), 28S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Kasari, V, Pochopien, A.A, Margus, T, Murina, V, Turnbull, K, Zhou, Y, Nissan, T, Graf, M, Novacek, J, Atkinson, G.C, Johansson, M.J.O, Wilson, D.N, Hauryliuk, V. Deposit date: 2019-06-26 Release date: 2019-07-24 Last modified: 2025-04-09 Method: ELECTRON MICROSCOPY (3.28 Å) Cite: A role for the Saccharomyces cerevisiae ABCF protein New1 in translation termination/recycling. Nucleic Acids Res., 47, 2019
4FT4	crystal structure of Zea mays ZMET2 in complex H3(1-32)K9me2 peptide and SAH Descriptor: DNA (cytosine-5)-methyltransferase 1, H3(1-32)K9me2 peptide, S-ADENOSYL-L-HOMOCYSTEINE Authors: Du, J, Patel, D.J. Deposit date: 2012-06-27 Release date: 2012-10-17 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants. Cell(Cambridge,Mass.), 151, 2012
7R76	Cryo-EM structure of DNMT5 in apo state Descriptor: DNA repair protein Rad8, ZINC ION Authors: Wang, J, Patel, D.J. Deposit date: 2021-06-24 Release date: 2022-02-23 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural insights into DNMT5-mediated ATP-dependent high-fidelity epigenome maintenance. Mol.Cell, 82, 2022
7R77	Cryo-EM structure of DNMT5 binary complex with hemimethylated DNA Descriptor: DNA (5'-D(P*GP*TP*CP*AP*GP*(5CM)P*GP*CP*AP*TP*GP*G)-3'), DNA repair protein Rad8, ZINC ION Authors: Wang, J, Patel, D.J. Deposit date: 2021-06-24 Release date: 2022-02-23 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural insights into DNMT5-mediated ATP-dependent high-fidelity epigenome maintenance. Mol.Cell, 82, 2022
7R78	cryo-EM structure of DNMT5 quaternary complex with hemimethylated DNA, AMP-PNP and SAH Descriptor: DNA (5'-D(*TP*GP*CP*GP*CP*TP*GP*AP*CP*A)-3'), DNA (5'-D(P*CP*AP*GP*(5CM)P*GP*CP*AP*T)-3'), DNA repair protein Rad8, ... Authors: Wang, J, Patel, D.J. Deposit date: 2021-06-24 Release date: 2022-02-23 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural insights into DNMT5-mediated ATP-dependent high-fidelity epigenome maintenance. Mol.Cell, 82, 2022
4FSX	crystal structure of Se-substituted Zea mays ZMET2 in complex with SAH Descriptor: DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE Authors: Du, J, Patel, D.J. Deposit date: 2012-06-27 Release date: 2012-10-17 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants. Cell(Cambridge,Mass.), 151, 2012
6RYU	Nucleosome-CHD4 complex structure (two CHD4 copies) Descriptor: Chromodomain-helicase-DNA-binding protein 4,CHD4,Chromodomain-helicase-DNA-binding protein 4, DNA (149-MER), Histone H2A type 1, ... Authors: Farnung, L, Ochmann, M, Cramer, P. Deposit date: 2019-06-12 Release date: 2020-07-15 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (4 Å) Cite: Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations. Elife, 9, 2020
7T02	Cryo-EM structure of DNMT5 pseudo-ternary complex solved by incubation with hemimethylated DNA and SAM Descriptor: DNA (5'-D(*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*CP*A)-3'), DNA (5'-D(P*GP*TP*CP*AP*GP*(5CM)P*GP*CP*AP*TP*GP*G)-3'), DNA repair protein Rad8, ... Authors: Wang, J, Patel, D.J. Deposit date: 2021-11-29 Release date: 2022-02-23 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structural insights into DNMT5-mediated ATP-dependent high-fidelity epigenome maintenance. Mol.Cell, 82, 2022
4FT2	crystal structure of Zea mays ZMET2 in complex H3(1-15)K9me2 peptide and SAH Descriptor: DNA (cytosine-5)-methyltransferase 1, H3 peptide, S-ADENOSYL-L-HOMOCYSTEINE Authors: Du, J, Patel, D.J. Deposit date: 2012-06-27 Release date: 2012-10-17 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants. Cell(Cambridge,Mass.), 151, 2012
7UBU	Crystal structure of ZMET2 in complex with hemimethylated CAG DNA and a histone H3Kc9me2 peptide Descriptor: 5MC SSDNA, C49 SSDNA, DNA (cytosine-5)-methyltransferase 1, ... Authors: Fang, J, Song, J. Deposit date: 2022-03-15 Release date: 2022-06-08 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.39 Å) Cite: Mechanistic basis for maintenance of CHG DNA methylation in plants. Nat Commun, 13, 2022
3MWY	Crystal structure of the chromodomain-ATPase portion of the yeast Chd1 chromatin remodeler Descriptor: Chromo domain-containing protein 1, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER Authors: Hauk, G, Bowman, G.D. Deposit date: 2010-05-06 Release date: 2010-09-29 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3.7 Å) Cite: The chromodomains of the Chd1 chromatin remodeler regulate DNA access to the ATPase motor. Mol.Cell, 39, 2010
9NH8	CHD1-nucleosome complex (anchored state) Descriptor: ARGININE, Chromodomain-helicase-DNA-binding protein 1, DNA (158-MER), ... Authors: James, A.M, Farnung, L. Deposit date: 2025-02-24 Release date: 2025-05-07 Last modified: 2025-05-28 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural basis of human CHD1 nucleosome recruitment and pausing. Mol.Cell, 85, 2025
9MVY	Crystal structure of ZMET2 in complex with unmethylated CTG DNA and a histone H3Kc9me2 peptide Descriptor: C49 ssDNA, DNA (cytosine-5)-methyltransferase 1, Histone H3.2, ... Authors: Herle, G, Fang, J, Song, J. Deposit date: 2025-01-16 Release date: 2025-05-21 Last modified: 2025-05-28 Method: X-RAY DIFFRACTION (2.71 Å) Cite: Structure of an Unfavorable de Novo DNA Methylation Complex of Plant Methyltransferase ZMET2. J.Mol.Biol., 437, 2025
9N6K	2.88 A S.cerevisiae Chd1[L886G/L889G/L891G]-nucleosome 2:1 complex with DNA-binding domain Descriptor: Chromo domain-containing protein 1, DNA Lagging Strand, DNA Tracking Strand, ... Authors: Nodelman, I.M, Folkwein, H.J, Armache, J.-P, Bowman, G.D. Deposit date: 2025-02-05 Release date: 2025-06-11 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: A competitive regulatory mechanism of the Chd1 remodeler is integral to distorting nucleosomal DNA. Nat.Struct.Mol.Biol., 2025
9N6H	2.54 A S.cerevisiae Chd1[L886G/L889G/L891G]-nucleosome 1:1 complex Descriptor: Chromo domain-containing protein 1, DNA Lagging Strand, DNA Tracking Strand, ... Authors: Nodelman, I.M, Folkwein, H.J, Armache, J.-P, Bowman, G.D. Deposit date: 2025-02-05 Release date: 2025-06-11 Method: ELECTRON MICROSCOPY (2.54 Å) Cite: A competitive regulatory mechanism of the Chd1 remodeler is integral to distorting nucleosomal DNA. Nat.Struct.Mol.Biol., 2025
9N6I	2.61 A S.cerevisiae Chd1[L886G/L889G/L891G]-nucleosome 2:1 complex Descriptor: Chromo domain-containing protein 1, DNA Lagging Strand, DNA Tracking Strand, ... Authors: Nodelman, I.M, Folkwein, H.J, Armache, J.-P, Bowman, G.D. Deposit date: 2025-02-05 Release date: 2025-06-11 Method: ELECTRON MICROSCOPY (2.61 Å) Cite: A competitive regulatory mechanism of the Chd1 remodeler is integral to distorting nucleosomal DNA. Nat.Struct.Mol.Biol., 2025
5E4W	Crystal structure of cpSRP43 chromodomains 2 and 3 in complex with the Alb3 tail Descriptor: CALCIUM ION, GLYCEROL, Inner membrane protein ALBINO3, ... Authors: Horn, A, Ahmed, Y.L, Wild, K, Sinning, I. Deposit date: 2015-10-07 Release date: 2015-12-02 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural basis for cpSRP43 chromodomain selectivity and dynamics in Alb3 insertase interaction. Nat Commun, 6, 2015

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