7R76

Cryo-EM structure of DNMT5 in apo state

Summary for 7R76

Entry DOI	10.2210/pdb7r76/pdb
EMDB information	24292
Descriptor	DNA repair protein Rad8, ZINC ION (2 entities in total)
Functional Keywords	cytosine-5 methyltransferase, snf2 atpase, transferase
Biological source	Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii)
Total number of polymer chains	1
Total formula weight	264138.70
Authors	Wang, J.,Patel, D.J. (deposition date: 2021-06-24, release date: 2022-02-23, Last modification date: 2022-03-30)
Primary citation	Wang, J.,Catania, S.,Wang, C.,de la Cruz, M.J.,Rao, B.,Madhani, H.D.,Patel, D.J. Structural insights into DNMT5-mediated ATP-dependent high-fidelity epigenome maintenance. Mol.Cell, 82:1186-1198.e6, 2022 Cited by PubMed: 35202575 DOI: 10.1016/j.molcel.2022.01.028 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation