7R76

Cryo-EM structure of DNMT5 in apo state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	DNA repair protein Rad8	polymer	2348	263811.7	1	UniProt (J9VI03)	Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii)
2	B, C, D, E, F (A)	ZINC ION	non-polymer		65.4	5	Chemie (ZN)

Sequence modifications

A: 58 - 2377 (UniProt: J9VI03)

PDB	External Database	Details
Met 30	-	expression tag
Ser 31	-	expression tag
Tyr 32	-	expression tag
Tyr 33	-	expression tag
His 34	-	expression tag
His 35	-	expression tag
His 36	-	expression tag
His 37	-	expression tag
His 38	-	expression tag
His 39	-	expression tag
Asp 40	-	expression tag
Tyr 41	-	expression tag
Asp 42	-	expression tag
Ile 43	-	expression tag
Pro 44	-	expression tag
Thr 45	-	expression tag
Thr 46	-	expression tag
Glu 47	-	expression tag
Asn 48	-	expression tag
Leu 49	-	expression tag
Tyr 50	-	expression tag
Phe 51	-	expression tag
Gln 52	-	expression tag
Gly 53	-	expression tag
Ala 54	-	expression tag
Met 55	-	expression tag
Gly 56	-	expression tag
Ser 57	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	263811.7
Non-Polymers*	Number of molecules	5
	Total formula weight	327.0
All*	Total formula weight	264138.7

*Water molecules are not included.