Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

4RT3
DownloadVisualize
BU of 4rt3 by Molmil
Ternary complex crystal structure of DNA polymerase Beta with (alpha, beta)-NH-(beta,gamma)-CH2-dTTP
Descriptor: 2'-deoxy-5'-O-[(S)-hydroxy{[(R)-hydroxy(phosphonomethyl)phosphoryl]amino}phosphoryl]-3,4-dihydrothymidine, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2014-11-12
Release date:2015-07-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Two Scaffolds from Two Flips: (alpha, beta)/(beta, gamma) CH2/NH "Met-Im" Analogues of dTTP.
Org.Lett., 17, 2015
8ADM
DownloadVisualize
BU of 8adm by Molmil
Ternary complex of 14-3-3 sigma, Usp8pS718 phosphopeptide and small molecule stabilizer
Descriptor: 1-[2-(4-chloranylphenoxy)-2-methyl-propanoyl]-~{N}-[2-[2-(dimethylamino)ethyldisulfanyl]ethyl]piperidine-4-carboxamide, 14-3-3 protein sigma, Ubiquitin carboxyl-terminal hydrolase 8
Authors:Centorrino, F, Ottmann, C.
Deposit date:2022-07-08
Release date:2023-04-26
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A Systematic Approach to the Discovery of Protein-Protein Interaction Stabilizers.
Acs Cent.Sci., 9, 2023
1KS8
DownloadVisualize
BU of 1ks8 by Molmil
The structure of Endoglucanase from termite, Nasutitermes takasagoensis, at pH 2.5.
Descriptor: Endo-b-1,4-glucanase, SULFATE ION
Authors:Khademi, S, Guarino, L.A, Watanabe, H, Tokuda, G, Meyer, E.F.
Deposit date:2002-01-11
Release date:2003-01-21
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of an endoglucanase from termite, Nasutitermes takasagoensis.
Acta Crystallogr.,Sect.D, 58, 2002
3HX0
DownloadVisualize
BU of 3hx0 by Molmil
ternary complex of L277A, H511A, R514 mutant pol lambda bound to a 2 nucleotide gapped DNA substrate with a scrunched dA
Descriptor: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*AP*GP*TP*AP*T)-3', 5'-D(*CP*GP*GP*CP*AP*AP*AP*TP*AP*CP*TP*G)-3', ...
Authors:Garcia-Diaz, M, Bebenek, K, Larrea, A.A, Havener, J.M, Perera, L, Krahn, J.M, Pedersen, L.C, Ramsden, D.A, Kunkel, T.A.
Deposit date:2009-06-19
Release date:2009-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Scrunching During DNA Repair Synthesis
To be Published
9IAD
DownloadVisualize
BU of 9iad by Molmil
Chroococcidiopsis thermalis Argonaute (CtAgo) bound to the 3' end of a guide DNA
Descriptor: DNA (5'-D(P*TP*TP*GP*T)-3'), Protein argonaute
Authors:Bobadilla Ugarte, P, Swarts, D.C.
Deposit date:2025-02-09
Release date:2025-04-23
Last modified:2025-05-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Cyanobacterial Argonautes and Cas4 family nucleases cooperate to interfere with invading DNA.
Mol.Cell, 85, 2025
8W53
DownloadVisualize
BU of 8w53 by Molmil
Crystal structure of LbUGT in complex with UDP
Descriptor: GLYCEROL, Glycosyltransferase, URIDINE-5'-DIPHOSPHATE
Authors:Hu, D, Wang, G.Q.
Deposit date:2023-08-25
Release date:2024-05-22
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (2.42816162 Å)
Cite:Functional and structural dissection of glycosyltransferases underlying the glycodiversity of wolfberry-derived bioactive ingredients lycibarbarspermidines.
Nat Commun, 15, 2024
5XFQ
DownloadVisualize
BU of 5xfq by Molmil
Ternary complex of PHF1, a DNA duplex and a histone peptide
Descriptor: DNA (5'-D(*GP*GP*GP*CP*GP*GP*CP*CP*GP*CP*CP*CP*T)-3'), PHD finger protein 1, Peptide from Histone H3, ...
Authors:Wang, Z, Li, H.
Deposit date:2017-04-11
Release date:2017-09-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Polycomb-like proteins link the PRC2 complex to CpG islands
Nature, 549, 2017
5K2H
DownloadVisualize
BU of 5k2h by Molmil
Structure of GNNQQNY from yeast prion Sup35 in space group P212121 determined by MicroED
Descriptor: Eukaryotic peptide chain release factor GTP-binding subunit
Authors:Rodriguez, J.A, Sawaya, M.R, Cascio, D, Eisenberg, D.S.
Deposit date:2016-05-18
Release date:2016-09-14
Last modified:2024-03-06
Method:ELECTRON CRYSTALLOGRAPHY (1.05 Å)
Cite:Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED.
Proc.Natl.Acad.Sci.USA, 113, 2016
7TIF
DownloadVisualize
BU of 7tif by Molmil
2.85 Angstroem crystal structure of Arginyltransferase 1 (ATE1) from Saccharomyces cerevisiae
Descriptor: Arginyl-tRNA--protein transferase 1, GLYCEROL, SULFATE ION
Authors:Van, V, Ejimogu, N.-E, Smith, A.T.
Deposit date:2022-01-13
Release date:2022-09-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:The Structure of Saccharomyces cerevisiae Arginyltransferase 1 (ATE1).
J.Mol.Biol., 434, 2022
7SCD
DownloadVisualize
BU of 7scd by Molmil
Ternary complex of fixed-arm Trx-3ost5 (I299E) with 8mer-1 octasaccharide substrate and co-factor product PAP
Descriptor: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, ADENOSINE-3'-5'-DIPHOSPHATE, Thioredoxin 1,Heparan sulfate glucosamine 3-O-sulfotransferase 5
Authors:Wander, R, Kaminski, A.M, Krahn, J.M, Liu, J, Pedersen, L.C.
Deposit date:2021-09-27
Release date:2022-01-19
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and Substrate Specificity Analysis of 3-O-Sulfotransferase Isoform 5 to Synthesize Heparan Sulfate
Acs Catalysis, 11, 2021
7SCE
DownloadVisualize
BU of 7sce by Molmil
Ternary complex of fixed-arm Trx-3ost5 (I299E) with 8mer-2 octasaccharide substrate and co-factor product PAP
Descriptor: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, ADENOSINE-3'-5'-DIPHOSPHATE, Thioredoxin 1,Heparan sulfate glucosamine 3-O-sulfotransferase 5
Authors:Wander, R, Kaminski, A.M, Krahn, J.M, Liu, J, Pedersen, L.C.
Deposit date:2021-09-27
Release date:2022-01-19
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural and Substrate Specificity Analysis of 3-O-Sulfotransferase Isoform 5 to Synthesize Heparan Sulfate
Acs Catalysis, 11, 2021
7VG8
DownloadVisualize
BU of 7vg8 by Molmil
TYLCV Rep-DNA
Descriptor: DNA (5'-((DT)P*(DA)P*(DA)P*(DT)P*(DA)P*(DT)P*(DT)P*(DA)*(DC)P*)-3'), MANGANESE (II) ION, Replication-associated protein
Authors:Zhang, S.Y, Wang, C.N.
Deposit date:2021-09-14
Release date:2022-09-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:structure of TYLCV Rep complexed with ssDNA
To Be Published
7CJN
DownloadVisualize
BU of 7cjn by Molmil
grass carp interleukin-2
Descriptor: Interleukin
Authors:Wang, J.
Deposit date:2020-07-12
Release date:2021-07-14
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Structural insights into the co-evolution of IL-2 and its private receptor
To Be Published
7VZT
DownloadVisualize
BU of 7vzt by Molmil
A human neutralizing antibody targeting SARS-CoV-2 RBD
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GH12-Heavy, GH12-LIGHT, ...
Authors:Wang, F.Z, Wang, Y, Tan, X.W, Shi, R, Yan, J.H.
Deposit date:2021-11-16
Release date:2023-05-31
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:GH12, glycosylation function
To Be Published
5GW6
DownloadVisualize
BU of 5gw6 by Molmil
Water-Bridge Mediates Recognition of mRNA Cap in eIF4E
Descriptor: Eukaryotic translation initiation factor 4E, GLYCEROL
Authors:Brown, C.J.
Deposit date:2016-09-08
Release date:2016-10-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Water-Bridge Mediates Recognition of mRNA Cap in eIF4E
Structure, 25, 2017
7LNU
DownloadVisualize
BU of 7lnu by Molmil
Ternary complex of the Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus bound to isopentenyl monophosphate and ATP
Descriptor: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Thomas, L.M, Singh, S, Scull, E.M, Bourne, C.R.
Deposit date:2021-02-08
Release date:2021-12-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular Basis for the Substrate Promiscuity of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus .
Acs Chem.Biol., 17, 2022
7LNT
DownloadVisualize
BU of 7lnt by Molmil
Ternary complex of the Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus bound to benzyl monophosphate and ATP
Descriptor: (phenylmethyl) dihydrogen phosphate, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ...
Authors:Thomas, L.M, Singh, S, Scull, E.M, Bourne, C.R.
Deposit date:2021-02-08
Release date:2021-12-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Molecular Basis for the Substrate Promiscuity of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus .
Acs Chem.Biol., 17, 2022
6Z03
DownloadVisualize
BU of 6z03 by Molmil
DNA Topoisomerase
Descriptor: DNA topoisomerase I
Authors:Takahashi, T.S, Gadelle, D, Forterre, P, Mayer, C, Petrella, S.
Deposit date:2020-05-07
Release date:2021-11-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Topoisomerase I (TOP1) dynamics: conformational transition from open to closed states.
Nat Commun, 13, 2022
7FB6
DownloadVisualize
BU of 7fb6 by Molmil
C57D/C146D mutant of Human Cu, Zn Superoxide Dismutase (SOD1)
Descriptor: CHLORIDE ION, COPPER (II) ION, Superoxide dismutase [Cu-Zn], ...
Authors:Baek, Y, Ha, N.-C.
Deposit date:2021-07-08
Release date:2022-10-12
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of the overoxidized Cu/Zn-superoxide dismutase in ROS-induced ALS filament formation.
Commun Biol, 5, 2022
7FB9
DownloadVisualize
BU of 7fb9 by Molmil
Crystal Structure of Human Cu, Zn Superoxide Dismutase (SOD1)
Descriptor: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION
Authors:Baek, Y, Ha, N.-C.
Deposit date:2021-07-08
Release date:2022-10-12
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural analysis of the overoxidized Cu/Zn-superoxide dismutase in ROS-induced ALS filament formation.
Commun Biol, 5, 2022
7ZNJ
DownloadVisualize
BU of 7znj by Molmil
Structure of an ALYREF-exon junction complex hexamer
Descriptor: Eukaryotic initiation factor 4A-III, N-terminally processed, MAGNESIUM ION, ...
Authors:Pacheco-Fiallos, F.B, Vorlaender, M.K, Plaschka, C.
Deposit date:2022-04-21
Release date:2023-04-12
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:mRNA recognition and packaging by the human transcription-export complex.
Nature, 616, 2023
5NOD
DownloadVisualize
BU of 5nod by Molmil
PASTA subunit 4 of Streptococcus pneumoniae STKP crystallized with PEG and succinate
Descriptor: Serine/threonine-protein kinase StkP
Authors:Galisson, F, Gueguen-Chaignon, V, Gouet, P, Grangeasse, C, Zucchini, L.
Deposit date:2017-04-12
Release date:2017-11-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:PASTA repeats of the protein kinase StkP interconnect cell constriction and separation of Streptococcus pneumoniae.
Nat Microbiol, 3, 2018
8QS4
DownloadVisualize
BU of 8qs4 by Molmil
Ternary structure of 14-3-3s, C-RAF phosphopeptide (pS259) and compound 22 (1083853)
Descriptor: 14-3-3 protein sigma, C-RAF peptide pS259, CHLORIDE ION, ...
Authors:Konstantinidou, M, Vickery, H, Pennings, M.A.M, Virta, J, Visser, E.J, Oetelaar, M.C.M, Overmans, M, Neitz, J, Ottmann, C, Brunsveld, L, Arkin, M.R.
Deposit date:2023-10-10
Release date:2025-04-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Small molecule stabilization of the 14-3-3sigma/CRAF complex inhibits the MAPK pathway
To Be Published
8QS7
DownloadVisualize
BU of 8qs7 by Molmil
Ternary structure of 14-3-3s, C-RAF phosphopeptide (pS259) and compound 70 (1084352)
Descriptor: 1-[8-(4-bromanyl-3-fluoranyl-phenyl)sulfonyl-5-oxa-2,8-diazaspiro[3.5]nonan-2-yl]-2-chloranyl-ethanone, 14-3-3 protein sigma, C-RAF peptide pS259, ...
Authors:Konstantinidou, M, Vickery, H, Pennings, M.A.M, Virta, J, Visser, E.J, Oetelaar, M.C.M, Overmans, M, Neitz, J, Ottmann, C, Brunsveld, L, Arkin, M.R.
Deposit date:2023-10-10
Release date:2025-04-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Small molecule stabilization of the 14-3-3sigma/CRAF complex inhibits the MAPK pathway
To Be Published
8QSE
DownloadVisualize
BU of 8qse by Molmil
Ternary structure of 14-3-3s, BRAF phosphopeptide (pS365) and compound 23 (1083848).
Descriptor: 14-3-3 protein sigma, 2-chloranyl-~{N}-[[1-(4-iodophenyl)sulfonylpiperidin-4-yl]methyl]ethanamide, BRAF peptide pS365, ...
Authors:Konstantinidou, M, Vickery, H, Pennings, M.A.M, Virta, J, Visser, E.J, Oetelaar, M.C.M, Overmans, M, Neitz, J, Ottmann, C, Brunsveld, L, Arkin, M.R.
Deposit date:2023-10-10
Release date:2025-04-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Small molecule stabilization of the 14-3-3sigma/CRAF complex inhibits the MAPK pathway
To Be Published

238582

数据于2025-07-09公开中

PDB statisticsPDBj update infoContact PDBjnumon