8F9M
 
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8F9G
 | | HIV Env germline targeting BG505_MD64_N332-GT5 SOSIP in complex with V3-glycan polyclonal Fab isolated from immunized BG18HCgl knock-in mice | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505_MD64_N332-GT5 gp120, ... | | Authors: | Ozorowski, G, Torres, J.L, Ward, A.B. | | Deposit date: | 2022-11-23 | | Release date: | 2024-05-15 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | mRNA-LNP HIV-1 trimer boosters elicit precursors to broad neutralizing antibodies.
Science, 384, 2024
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2RUG
 | | Refined solution structure of the first RNA recognition motif domain in CPEB3 | | Descriptor: | Cytoplasmic polyadenylation element-binding protein 3 | | Authors: | Tsuda, K, Kuwasako, K, Nagata, T, Takahashi, M, Kigawa, T, Kobayashi, N, Guntert, P, Shirouzu, M, Yokoyama, S, Muto, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2014-04-15 | | Release date: | 2014-09-17 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Novel RNA recognition motif domain in the cytoplasmic polyadenylation element binding protein 3.
Proteins, 82, 2014
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7O6N
 | | Crystal structure of C. elegans ERH-2 PID-3 complex | | Descriptor: | Enhancer of rudimentary homolog 2, FORMIC ACID, Protein pid-3 | | Authors: | Falk, S, Ketting, R.F. | | Deposit date: | 2021-04-11 | | Release date: | 2021-08-25 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans .
Genes Dev., 35, 2021
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5XC7
 | | Dengue Virus 4 NS3 Helicase D290A mutant | | Descriptor: | CHLORIDE ION, GLYCEROL, NS3 Helicase | | Authors: | Swarbrick, C.M.D, Basavannacharya, C, Chan, K.W.K, Chan, S.A, Singh, D, Wei, N, Phoo, W.W, Luo, D, Lescar, J, Vasudevan, S.G. | | Deposit date: | 2017-03-22 | | Release date: | 2017-11-08 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replication
Nucleic Acids Res., 45, 2017
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3L29
 | | Crystal Structure of Zaire Ebola VP35 interferon inhibitory domain K319A/R322A mutant | | Descriptor: | CHLORIDE ION, Polymerase cofactor VP35 | | Authors: | Leung, D.W, Ramanan, P, Borek, D.M, Amarasinghe, G.K. | | Deposit date: | 2009-12-14 | | Release date: | 2010-02-02 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Mutations abrogating VP35 interaction with double-stranded RNA render ebola virus avirulent in guinea pigs.
J.Virol., 84, 2010
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4JXJ
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3KWR
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3BSO
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6OTC
 | | Synthetic Fab bound to Marburg virus VP35 interferon inhibitory domain | | Descriptor: | CHLORIDE ION, GLYCEROL, Polymerase cofactor VP35, ... | | Authors: | Amatya, P, Chen, G, Borek, D, Sidhu, S.S, Leung, D.W. | | Deposit date: | 2019-05-02 | | Release date: | 2019-06-05 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Inhibition of Marburg Virus RNA Synthesis by a Synthetic Anti-VP35 Antibody.
Acs Infect Dis., 5, 2019
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2XI3
 | | HCV-H77 NS5B Polymerase Complexed With GTP | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA-directed RNA polymerase | | Authors: | Harrus, D, Ahmed-El-Sayed, N, Simister, P.C, Miller, S, Triconnet, M, Hagedorn, C.H, Mahias, K, Rey, F.A, Astier-Gin, T, Bressanelli, S. | | Deposit date: | 2010-06-25 | | Release date: | 2010-08-04 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Further Insights Into the Roles of GTP and the C- Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis
J.Biol.Chem., 285, 2010
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2XHV
 | | HCV-J4 NS5B Polymerase Point Mutant Orthorhombic Crystal Form | | Descriptor: | MAGNESIUM ION, RNA-directed RNA polymerase, SULFATE ION | | Authors: | Harrus, D, Ahmed-El-Sayed, N, Simister, P.C, Miller, S, Triconnet, M, Hagedorn, C.H, Mahias, K, Rey, F.A, Astier-Gin, T, Bressanelli, S. | | Deposit date: | 2010-06-21 | | Release date: | 2010-08-04 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Further Insights Into the Roles of GTP and the C- Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis
J.Biol.Chem., 285, 2010
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1LDZ
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3BSN
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2YWK
 | | Crystal structure of RRM-domain derived from human putative RNA-binding protein 11 | | Descriptor: | Putative RNA-binding protein 11 | | Authors: | Kawazoe, M, Takemoto, C, Kaminishi, T, Uchikubo-Kamo, T, Nishino, A, Morita, S, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-04-20 | | Release date: | 2008-04-22 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | Crystal structure of RRM-domain derived from human putative RNA-binding protein 11
To be Published
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8QG0
 | | Archaeoglobus fulgidus AfAgo complex with AfAgo-N protein (fAfAgo) bound with 17 nt RNA guide and 17 nt DNA target | | Descriptor: | AfAgo-N protein, DNA target 17 nt, Piwi protein, ... | | Authors: | Manakova, E.N, Zaremba, M, Pocevicuite, R, Golovinas, E, Zagorskaite, E, Silanskas, A. | | Deposit date: | 2023-09-05 | | Release date: | 2024-01-24 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.43 Å) | | Cite: | The missing part: the Archaeoglobus fulgidus Argonaute forms a functional heterodimer with an N-L1-L2 domain protein.
Nucleic Acids Res., 52, 2024
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1X48
 | | Solution structure of the second DSRM domain in Interferon-induced, double-stranded RNA-activated protein kinase | | Descriptor: | Interferon-induced, double-stranded RNA-activated protein kinase | | Authors: | He, F, Muto, Y, Inoue, M, Tarada, T, Shirouzu, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-05-14 | | Release date: | 2005-11-14 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the second DSRM domain in Interferon-induced, double-stranded RNA-activated protein kinase
To be Published
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3IG1
 | | HIV-1 Reverse Transcriptase with the Inhibitor beta-Thujaplicinol Bound at the RNase H Active Site | | Descriptor: | 2,7-dihydroxy-4-(propan-2-yl)cyclohepta-2,4,6-trien-1-one, HIV-1 Reverse Transcriptase p51 subunit, HIV-1 Reverse Transcriptase p66 subunit, ... | | Authors: | Himmel, D.M, Maegley, K.A, Pauly, T.A, Arnold, E. | | Deposit date: | 2009-07-27 | | Release date: | 2010-01-26 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of HIV-1 reverse transcriptase with the inhibitor beta-Thujaplicinol bound at the RNase H active site.
Structure, 17, 2009
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1X49
 | | Solution structure of the first DSRM domain in Interferon-induced, double-stranded RNA-activated protein kinase | | Descriptor: | Interferon-induced, double-stranded RNA-activated protein kinase | | Authors: | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-05-14 | | Release date: | 2005-11-14 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the first DSRM domain in Interferon-induced, double-stranded RNA-activated protein kinase
To be Published
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2I5J
 | | Crystal structure of HIV-1 reverse transcriptase (RT) in complex with DHBNH, an RNASE H inhibitor | | Descriptor: | (E)-3,4-DIHYDROXY-N'-[(2-METHOXYNAPHTHALEN-1-YL)METHYLENE]BENZOHYDRAZIDE, MAGNESIUM ION, Reverse transcriptase/ribonuclease H P51 subunit, ... | | Authors: | Himmel, D.M, Sarafianos, S.G, Knight, J.L, Levy, R.M, Arnold, E. | | Deposit date: | 2006-08-24 | | Release date: | 2006-12-05 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | HIV-1 reverse transcriptase structure with RNase H inhibitor dihydroxy benzoyl naphthyl hydrazone bound at a novel site.
Acs Chem.Biol., 1, 2006
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6CK4
 | | G96A mutant of the PRPP riboswitch from T. mathranii bound to ppGpp | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, GUANOSINE-5',3'-TETRAPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Reiss, C.W, Knappenberger, A.J, Strobel, S.A. | | Deposit date: | 2018-02-27 | | Release date: | 2018-06-20 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.097 Å) | | Cite: | Structures of two aptamers with differing ligand specificity reveal ruggedness in the functional landscape of RNA.
Elife, 7, 2018
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4YBG
 | | Crystal structure of the MAEL domain of Drosophila melanogaster Maelstrom | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Protein maelstrom, ... | | Authors: | Matsumoto, N, Ishitani, R, Nishimasu, H, Nureki, O. | | Deposit date: | 2015-02-18 | | Release date: | 2015-04-29 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.602 Å) | | Cite: | Crystal Structure and Activity of the Endoribonuclease Domain of the piRNA Pathway Factor Maelstrom
Cell Rep, 11, 2015
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5YQ3
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4JG3
 | | Crystal structure of catabolite repression control protein (crc) from Pseudomonas aeruginosa | | Descriptor: | CHLORIDE ION, Catabolite repression control protein | | Authors: | Grishkovskaya, I, Milojevic, T, Sonnleitner, E, Blaesi, U, Djinovic-Carugo, K. | | Deposit date: | 2013-02-28 | | Release date: | 2013-06-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The Pseudomonas aeruginosa Catabolite Repression Control Protein Crc Is Devoid of RNA Binding Activity
Plos One, 8, 2013
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2P38
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