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3AUV
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BU of 3auv by Molmil
Predicting Amino Acid Preferences in the Complementarity Determining Regions of an Antibody-Antigen Recognition Interface
Descriptor: sc-dsFv derived from the G6-Fab
Authors:Yu, C.M, Peng, H.P, Chen, I.C, Lee, Y.C, Chen, J.B, Tsai, K.C, Chen, C.T, Chang, J.Y, Yang, E.W, Hsu, P.C, Jian, J.W, Hsu, H.J, Chang, H.J, Hsu, W.L, Huang, K.F, Ma, A.C, Yang, A.S.
Deposit date:2011-02-16
Release date:2012-02-22
Last modified:2012-04-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Rationalization and design of the complementarity determining region sequences in an antibody-antigen recognition interface
Plos One, 7, 2012
2DQU
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Crystal form II: high resolution crystal structure of the complex of the hydrolytic antibody Fab 6D9 and a transition-state analog
Descriptor: IMMUNOGLOBULIN 6D9, [1-(3-DIMETHYLAMINO-PROPYL)-3-ETHYL-UREIDO]-[4-(2,2,2-TRIFLUORO-ACETYLAMINO)-BENZYL]PHOSPHINIC ACID-2-(2,2-DIHYDRO-ACETYLAMINO)-3-HYDROXY-1-(4-NITROPHENYL)-PROPYL ESTER
Authors:Kristensen, O, Vassylyev, D.G, Tanaka, F, Ito, N, Morikawa, K, Fujii, I.
Deposit date:2006-05-30
Release date:2006-06-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Thermodynamic and structural basis for transition-state stabilization in antibody-catalyzed hydrolysis
J.Mol.Biol., 369, 2007
2DQT
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High resolution crystal structure of the complex of the hydrolytic antibody Fab 6D9 and a transition-state analog
Descriptor: IMMUNOGLOBULIN 6D9, [1-(3-DIMETHYLAMINO-PROPYL)-3-ETHYL-UREIDO]-[4-(2,2,2-TRIFLUORO-ACETYLAMINO)-BENZYL]PHOSPHINIC ACID-2-(2,2-DIHYDRO-ACETYLAMINO)-3-HYDROXY-1-(4-NITROPHENYL)-PROPYL ESTER
Authors:Kristensen, O, Vassylyev, D.G, Tanaka, F, Ito, N, Morikawa, K, Fujii, I.
Deposit date:2006-05-30
Release date:2006-06-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Thermodynamic and structural basis for transition-state stabilization in antibody-catalyzed hydrolysis
J.Mol.Biol., 369, 2007
2DTM
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Thermodynamic and structural analyses of hydrolytic mechanism by catalytic antibodies
Descriptor: IMMUNOGLOBULIN 6D9
Authors:Oda, M, Ito, N, Tsumuraya, T, Suzuki, K, Fujii, I.
Deposit date:2006-07-13
Release date:2007-05-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Thermodynamic and structural basis for transition-state stabilization in antibody-catalyzed hydrolysis
J.Mol.Biol., 369, 2007
1TOS
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BU of 1tos by Molmil
TORPEDO CALIFORNICA ACHR RECEPTOR [ALA76] ANALOGUE COMPLEXED WITH THE ANTI-ACETYLCHOLINE MAB6 MONOCLONAL ANTIBODY
Descriptor: ACETYLCHOLINE RECEPTOR [ALA76] MIR ANALOGUE
Authors:Orlewski, P, Tsikaris, V, Sakarellos, C, Sakarellos-Daistiotis, M, Vatzaki, E, Tzartos, S.J, Marraud, M, Cung, M.T.
Deposit date:1995-10-11
Release date:1996-03-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Compared structures of the free nicotinic acetylcholine receptor main immunogenic region (MIR) decapeptide and the antibody-bound [A76]MIR analogue: a molecular dynamics simulation from two-dimensional NMR data.
Biopolymers, 40, 1996
2G75
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BU of 2g75 by Molmil
Crystal Structure of anti-SARS m396 Antibody
Descriptor: IGG Heavy Chain, IGG Light Chain
Authors:Prabakaran, P, Gan, J.H, Feng, Y, Zhu, Z.Y, Xiao, X.D, Ji, X, Dimitrov, D.S.
Deposit date:2006-02-27
Release date:2006-04-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structure of severe acute respiratory syndrome coronavirus receptor-binding domain complexed with neutralizing antibody.
J.Biol.Chem., 281, 2006
43CA
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BU of 43ca by Molmil
CRYSTALLOGRAPHIC STRUCTURE OF THE ESTEROLYTIC AND AMIDOLYTIC 43C9 ANTIBODY WITH BOUND P-NITROPHENOL
Descriptor: P-NITROPHENOL, PROTEIN (IMMUNOGLOBULIN (HEAVY CHAIN)), PROTEIN (IMMUNOGLOBULIN (LIGHT CHAIN))
Authors:Thayer, M.M, Getzoff, E.D, Roberts, V.A.
Deposit date:1999-03-10
Release date:1999-08-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for amide hydrolysis catalyzed by the 43C9 antibody.
J.Mol.Biol., 291, 1999
4S2S
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BU of 4s2s by Molmil
Crystal Structure of Fab fragment of monoclonal antibody RoAb13
Descriptor: RoAb13 Fab Heavy chain, RoAb13 Fab Light chain
Authors:Chain, B, Arnold, J, Akthar, S, Noursadeghi, M, Lapp, T, Ji, C, Naider, D, Zhang, Y, Govada, L, Saridakis, E, Chayen, N.E.
Deposit date:2015-01-22
Release date:2015-06-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Linear Epitope in the N-Terminal Domain of CCR5 and Its Interaction with Antibody.
Plos One, 10, 2015
43C9
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CRYSTALLOGRAPHIC STRUCTURE OF THE ESTEROLYTIC AND AMIDOLYTIC 43C9 ANTIBODY
Descriptor: PROTEIN (IMMUNOGLOBULIN (HEAVY CHAIN)), PROTEIN (IMMUNOGLOBULIN (LIGHT CHAIN))
Authors:Thayer, M.M, Getzoff, E.D, Roberts, V.A.
Deposit date:1999-03-10
Release date:1999-08-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for amide hydrolysis catalyzed by the 43C9 antibody.
J.Mol.Biol., 291, 1999
2DBL
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BU of 2dbl by Molmil
MOLECULAR BASIS OF CROSS-REACTIVITY AND THE LIMITS OF ANTIBODY-ANTIGEN COMPLEMENTARITY
Descriptor: 5-ALPHA-PREGNANE-3-BETA-OL-HEMISUCCINATE, IGG1-KAPPA DB3 FAB (HEAVY CHAIN), IGG1-KAPPA DB3 FAB (LIGHT CHAIN)
Authors:Arevalo, J.H, Wilson, I.A.
Deposit date:1994-02-08
Release date:1994-03-07
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular basis of crossreactivity and the limits of antibody-antigen complementarity.
Nature, 365, 1993
1NCC
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BU of 1ncc by Molmil
CRYSTAL STRUCTURES OF TWO MUTANT NEURAMINIDASE-ANTIBODY COMPLEXES WITH AMINO ACID SUBSTITUTIONS IN THE INTERFACE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, IGG2A-KAPPA NC41 FAB (HEAVY CHAIN), ...
Authors:Tulip, W.R, Varghese, J.N, Colman, P.M.
Deposit date:1992-01-21
Release date:1994-01-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of two mutant neuraminidase-antibody complexes with amino acid substitutions in the interface.
J.Mol.Biol., 227, 1992
1NCB
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BU of 1ncb by Molmil
CRYSTAL STRUCTURES OF TWO MUTANT NEURAMINIDASE-ANTIBODY COMPLEXES WITH AMINO ACID SUBSTITUTIONS IN THE INTERFACE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Tulip, W.R, Varghese, J.N, Colman, P.M.
Deposit date:1992-01-21
Release date:1994-01-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of two mutant neuraminidase-antibody complexes with amino acid substitutions in the interface.
J.Mol.Biol., 227, 1992
5JMO
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BU of 5jmo by Molmil
X-ray structure of furin in complex with the inhibitory antibody Nb14
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CMK-inhibitor, ...
Authors:Dahms, S.O, Than, M.E.
Deposit date:2016-04-29
Release date:2016-12-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.998 Å)
Cite:The structure of a furin-antibody complex explains non-competitive inhibition by steric exclusion of substrate conformers.
Sci Rep, 6, 2016
6IDK
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BU of 6idk by Molmil
Cryo-EM structure of Immature Dengue virus serotype 3 in complex with human antibody 1H10 Fab at pH 5.0 (Class I particle)
Descriptor: Envelope protein, Fab 1H10 heavy chain (V-region), Fab 1H10 light chain (V-region), ...
Authors:Wirawan, M, Fibriansah, G, Ng, T.S, Zhang, Q, Kostyuchenko, V.A, Shi, J, Lok, S.M.
Deposit date:2018-09-10
Release date:2018-12-12
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (25 Å)
Cite:Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody.
Structure, 27, 2019
6IDI
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BU of 6idi by Molmil
Cryo-EM structure of Immature Dengue virus serotype 3 in complex with human antibody 1H10 Fab at pH 8.0.
Descriptor: Envelope protein, Fab 1H10 heavy chain (V-region), Fab 1H10 light chain (V-region), ...
Authors:Wirawan, M, Fibriansah, G, Ng, T.S, Zhang, Q, Kostyuchenko, V.A, Shi, J, Lok, S.M.
Deposit date:2018-09-10
Release date:2018-12-12
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (12 Å)
Cite:Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody.
Structure, 27, 2019
6GV4
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BU of 6gv4 by Molmil
High-resolution Cryo-EM of Fab-labeled human parechovirus 3
Descriptor: AT12-015 antibody variable heavy, AT12-015 antibody variable light, RNA (5'-R(*UP*GP*GP*UP*AP*UP*UP*U)-3'), ...
Authors:Domanska, A, Flatt, J.W, Jukonen, J.J.J, Geraets, J.A, Butcher, S.J.
Deposit date:2018-06-20
Release date:2018-11-21
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:A 2.8-Angstrom-Resolution Cryo-Electron Microscopy Structure of Human Parechovirus 3 in Complex with Fab from a Neutralizing Antibody.
J.Virol., 93, 2019
6CH7
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BU of 6ch7 by Molmil
XFEL crystal structure of a natively-glycosylated BG505 SOSIP.664 HIV-1 Envelope Trimer in complex with the broadly-neutralizing antibodies BG18 and 35O22
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2018-02-22
Release date:2018-05-02
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope.
Nat Commun, 9, 2018
6CH9
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Crystal structure of a natively-glycosylated B41 SOSIP.664 HIV-1 Envelope Trimer in complex with the broadly-neutralizing antibodies BG18 and 35O22
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Heavy Chain, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2018-02-22
Release date:2018-05-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (4.85 Å)
Cite:Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope.
Nat Commun, 9, 2018
5KW9
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BU of 5kw9 by Molmil
Structural Basis for Norovirus Neutralization by a HBGA Blocking Human IgA Antibody
Descriptor: Capsid protein VP1, IgA Light chain, IgA(VH)-IgG(CH) heavy chain Fab fragment, ...
Authors:Shanker, S, Prasad, B.V.V.
Deposit date:2016-07-15
Release date:2016-10-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for norovirus neutralization by an HBGA blocking human IgA antibody.
Proc.Natl.Acad.Sci.USA, 113, 2016
6CH8
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BU of 6ch8 by Molmil
Crystal structure of a natively-glycosylated BG505 SOSIP.664 HIV-1 Envelope Trimer in complex with the broadly-neutralizing antibodies BG18 and 35O22
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Heavy Chain, 35O22 Light Chain, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2018-02-22
Release date:2018-05-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope.
Nat Commun, 9, 2018
4RX4
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BU of 4rx4 by Molmil
Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 8ANC134 in complex with HIV-1 clade A Q842.d12 gp120
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC134 Heavy chain, ...
Authors:Zhou, T, Acharya, P, Moquin, S, Kwong, P.D.
Deposit date:2014-12-08
Release date:2015-07-01
Last modified:2021-06-02
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell(Cambridge,Mass.), 161, 2015
2XEG
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Human glutamate carboxypeptidase II in complex with Antibody- Recruiting Molecule ARM-P4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Zhang, A.X, Murelli, R.P, Barinka, C, Michel, J, Cocleaza, A, Jorgensen, W.L, Lubkowski, J, Spiegel, D.A.
Deposit date:2010-05-14
Release date:2010-09-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:A Remote Arene-Binding Site on Prostate Specific Membrane Antigen Revealed by Antibody-Recruiting Small Molecules.
J.Am.Chem.Soc., 132, 2010
3HFM
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BU of 3hfm by Molmil
STRUCTURE OF AN ANTIBODY-ANTIGEN COMPLEX. CRYSTAL STRUCTURE OF THE HY/HEL-10 FAB-LYSOZYME COMPLEX
Descriptor: HEN EGG WHITE LYSOZYME, HYHEL-10 IGG1 FAB (HEAVY CHAIN), HYHEL-10 IGG1 FAB (LIGHT CHAIN)
Authors:Padlan, E.A, Davies, D.R.
Deposit date:1988-08-11
Release date:1989-07-12
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of an antibody-antigen complex: crystal structure of the HyHEL-10 Fab-lysozyme complex.
Proc.Natl.Acad.Sci.USA, 86, 1989
1A2Y
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HEN EGG WHITE LYSOZYME, D18A MUTANT, IN COMPLEX WITH MOUSE MONOCLONAL ANTIBODY D1.3
Descriptor: IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN), LYSOZYME, ...
Authors:Tsuchiya, D, Mariuzza, R.A.
Deposit date:1998-01-13
Release date:1998-04-29
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A mutational analysis of binding interactions in an antigen-antibody protein-protein complex.
Biochemistry, 37, 1998
5KOV
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BU of 5kov by Molmil
Crystal structure of the human astrovirus 2 capsid protein spike in complex with a single chain variable fragment of an astrovirus neutralizing antibody at 3.24-A resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid polyprotein VP90, PL-2 scFv chain
Authors:Bogdanoff, W.A, DuBois, R.M.
Deposit date:2016-07-01
Release date:2016-11-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.245 Å)
Cite:Structure of a Human Astrovirus Capsid-Antibody Complex and Mechanistic Insights into Virus Neutralization.
J. Virol., 91, 2017

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