2XEG

Human glutamate carboxypeptidase II in complex with Antibody- Recruiting Molecule ARM-P4

Summary for 2XEG

Entry DOI	10.2210/pdb2xeg/pdb
Related	1Z8L 2C6C 2C6G 2C6P 2CIJ 2JBJ 2JBK 2XEF 2XEI 2XEJ
Descriptor	GLUTAMATE CARBOXYPEPTIDASE 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
Functional Keywords	metallopeptidase, hydrolase
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cell membrane; Single-pass type II membrane protein. Isoform PSMA': Cytoplasm: Q04609
Total number of polymer chains	1
Total formula weight	83512.58
Authors	Zhang, A.X.,Murelli, R.P.,Barinka, C.,Michel, J.,Cocleaza, A.,Jorgensen, W.L.,Lubkowski, J.,Spiegel, D.A. (deposition date: 2010-05-14, release date: 2010-09-08, Last modification date: 2023-12-20)
Primary citation	Zhang, A.X.,Murelli, R.P.,Barinka, C.,Michel, J.,Cocleaza, A.,Jorgensen, W.L.,Lubkowski, J.,Spiegel, D.A. A Remote Arene-Binding Site on Prostate Specific Membrane Antigen Revealed by Antibody-Recruiting Small Molecules. J.Am.Chem.Soc., 132:12711-, 2010 Cited by PubMed: 20726553 DOI: 10.1021/JA104591M PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.59 Å)

Structure validation