1Z8L

Crystal structure of prostate-specific membrane antigen, a tumor marker and peptidase

Summary for 1Z8L

Entry DOI	10.2210/pdb1z8l/pdb
Descriptor	Glutamate carboxypeptidase II, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	dimeric protein with three domains of type a+b, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Cell membrane; Single-pass type II membrane protein. Isoform PSMA': Cytoplasm: Q04609
Total number of polymer chains	4
Total formula weight	324146.36
Authors	Davis, M.I.,Bennett, M.J.,Thomas, L.M.,Bjorkman, P.J. (deposition date: 2005-03-30, release date: 2005-04-19, Last modification date: 2023-08-23)
Primary citation	Davis, M.I.,Bennett, M.J.,Thomas, L.M.,Bjorkman, P.J. Crystal structure of prostate-specific membrane antigen, a tumor marker and peptidase Proc.Natl.Acad.Sci.USA, 102:5981-5986, 2005 Cited by PubMed: 15837926 DOI: 10.1073/pnas.0502101102 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.5 Å)

Structure validation