1Z8L

Crystal structure of prostate-specific membrane antigen, a tumor marker and peptidase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Glutamate carboxypeptidase II	polymer	695	78341.4	4	UniProt (Q04609) Pfam (PF02225) Pfam (PF04389) Pfam (PF04253) In PDB	Homo sapiens (human)	Membrane glutamate carboxypeptidase, mGCP, N-acetylated-alpha-linked acidic dipeptidase I, NAALADase I, Pteroylpoly-gamma-glutamate carboxypeptidase, Folylpoly-gamma-glutamate carboxypeptidase, FGCP, Folate hydrolase 1, Prostate-specific membrane antigen, PSMA, PSM
2	E, G, J, L, O...	2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	8	In PDB GlyTouCan (G07375KG)
3	F, H, I, K, M...	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	12	In PDB GlyTouCan (G42666HT)
4	B, C, D, A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	8	Chemie (NAG)
5	A, B, C, D	ZINC ION	non-polymer		65.4	8	Chemie (ZN)
6		water	water		18.0	12	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	313365.4
Branched	Number of molecules	20
	Total formula weight	8488.0
Non-Polymers*	Number of molecules	16
	Total formula weight	2292.9
All*	Total formula weight	324146.4

*Water molecules are not included.