PDB: 72372 resultsInfo pagesStatus searchChemie searchBIRD

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2AB4	Dissecting the Roles of a Strictly Conserved Tyrosine in Substrate Recognition and Catalysis by Pseudouridine 55 Synthase Descriptor: 5'-R(*CP*CP*AP*CP*GP*GP*UP*(FHU)P*CP*GP*AP*AP*UP*CP*CP*GP*UP*GP*GP*C)-3', ZINC ION, tRNA pseudouridine synthase B Authors: Phannachet, K, Elias, Y, Huang, R.H. Deposit date: 2005-07-14 Release date: 2005-12-13 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Dissecting the roles of a strictly conserved tyrosine in substrate recognition and catalysis by pseudouridine 55 synthase. Biochemistry, 44, 2005
4XLS	Crystal structure of T. aquaticus transcription initiation complex with CarD containing upstream fork promoter. Descriptor: CarD-like transcriptional regulator, DNA (30-MER), DNA (5'-D(P*GP*CP*AP*CP*AP*AP*TP*TP*TP*AP*AP*CP*AP*CP*TP*TP*TP*TP*GP*TP*CP*AP*AP*G)-3'), ... Authors: Bae, B, Darst, S.A. Deposit date: 2015-01-13 Release date: 2015-09-23 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (4.01 Å) Cite: CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex. Elife, 4, 2015
7Q4U	Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase holoenzyme octamer comprising sigma factor SigB Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Brodolin, K. Deposit date: 2021-11-02 Release date: 2022-11-16 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (4.39 Å) Cite: Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization Nat Commun, 14, 2023
8R6U	Structure of the SFTSV L protein in a transcription-priming state without capped RNA [TRANSCRIPTION-PRIMING (in vitro)] Descriptor: MAGNESIUM ION, RNA (5'-R(P*CP*UP*GP*GP*GP*CP*GP*GP*UP*CP*UP*UP*UP*GP*UP*GP*U)-3'), RNA primer, ... Authors: Williams, H.M, Thorkelsson, S.R, Vogel, D, Busch, C, Milewski, M, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M. Deposit date: 2023-11-23 Release date: 2024-04-24 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.98 Å) Cite: Structural snapshots of phenuivirus cap-snatching and transcription. Nucleic Acids Res., 52, 2024
8GY6	Structure of SARS-CoV-2 RNA-dependent RNA polymerase with gossypol binding Descriptor: Gossypol, Non-structural protein 7, Non-structural protein 8, ... Authors: Wang, W, Ren, M, Li, F. Deposit date: 2022-09-21 Release date: 2023-11-01 Method: ELECTRON MICROSCOPY Cite: Structure of SARS-CoV-2 RNA-dependent RNA polymerase with gossypol binding To Be Published
7BOE	Bacterial 30S ribosomal subunit assembly complex state M (Consensus refinement) Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... Authors: Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Lopez-Alonso, J, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.R. Deposit date: 2021-01-25 Release date: 2021-12-08 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
6MUA	Crystal structure of Csm1-Csm4 subcomplex in the type III-A CRISPR-Csm interference complex Descriptor: Uncharacterized protein Csm1, Uncharacterized protein Csm4 Authors: Jia, N, Patel, D.J. Deposit date: 2018-10-22 Release date: 2019-01-09 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.91 Å) Cite: Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity. Mol. Cell, 73, 2019
8QU5	mt-LSU assembly intermediate in GTPBP8 knock-out cells, state 2 Descriptor: 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... Authors: Valentin Gese, G, Cipullo, M, Rorbach, J, Hallberg, B.M. Deposit date: 2023-10-13 Release date: 2024-06-26 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (2.42 Å) Cite: GTPBP8 plays a role in mitoribosome formation in human mitochondria. Nat Commun, 15, 2024
8HCG	Crystal structure of mTREX1-dAMP complex Descriptor: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... Authors: Hsiao, Y.Y, Huang, K.W, Wu, C.Y. Deposit date: 2022-11-01 Release date: 2023-11-08 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.799 Å) Cite: Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51, 2023
8HCD	Crystal structure of mTREX1-DNA product complex (dNMP) Descriptor: 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, COBALT (II) ION, ... Authors: Hsiao, Y.Y, Huang, K.W, Wu, C.Y. Deposit date: 2022-11-01 Release date: 2023-11-08 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51, 2023
8HCE	Crystal structure of mTREX1-CMP complex Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AMMONIUM ION, CYTIDINE-5'-MONOPHOSPHATE, ... Authors: Hsiao, Y.Y, Huang, K.W, Wu, C.Y. Deposit date: 2022-11-01 Release date: 2023-11-08 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.501 Å) Cite: Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51, 2023
8HCF	Crystal structure of mTREX1-UMP complex Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION, Three-prime repair exonuclease 1, ... Authors: Hsiao, Y.Y, Huang, K.W, Wu, C.Y. Deposit date: 2022-11-01 Release date: 2023-11-08 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51, 2023
8HCH	Crystal structure of mTREX1-Uridine complex Descriptor: MAGNESIUM ION, Three-prime repair exonuclease 1, URIDINE Authors: Hsiao, Y.Y, Huang, K.W, Wu, C.Y. Deposit date: 2022-11-01 Release date: 2023-11-08 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51, 2023
3OIJ	Crystal structure of Saccharomyces Cerevisiae Nep1/Emg1 bound to S-adenosylhomocysteine and 2 molecules of cognate RNA Descriptor: 5'-R(*GP*GP*GP*CP*UP*UP*CP*AP*AP*CP*GP*CP*CP*C)-3', Essential for mitotic growth 1, MAGNESIUM ION, ... Authors: Thomas, S.R, LaRonde-LeBlanc, N. Deposit date: 2010-08-19 Release date: 2010-12-01 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis. Nucleic Acids Res., 39, 2011
6H02	Crystal structure of human Mediator subunit MED23 Descriptor: LAMA nanobody NB106, Mediator of RNA polymerase II transcription subunit 23 Authors: Clantin, B, Monte, D, Villeret, V. Deposit date: 2018-07-06 Release date: 2018-08-29 Last modified: 2018-09-05 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal structure of human Mediator subunit MED23. Nat Commun, 9, 2018
6X46	NMR solution structure of Asterix/Gtsf1 from mouse (CHHC zinc finger domains) Descriptor: Gametocyte-specific factor 1, ZINC ION Authors: Ipsaro, J.J, O'Brien, P.A, Bhattacharya, S, Palmer III, A.G, Joshua-Tor, L. Deposit date: 2020-05-22 Release date: 2021-03-03 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Asterix/Gtsf1 links tRNAs and piRNA silencing of retrotransposons. Cell Rep, 34, 2021
8PEL	Structure of C. thermophilum RNA exosome core Descriptor: Exoribonuclease phosphorolytic domain-containing protein, Exoribonuclease-like protein, Exosome complex component MTR3, ... Authors: Lazzaretti, D, Holdermann, I, Sprangers, R. Deposit date: 2023-06-14 Release date: 2024-06-26 Method: X-RAY DIFFRACTION (3.81 Å) Cite: Beyond static structures: quantitative dynamics in the eukaryotic RNA exosome complex Biorxiv, 2024
7MLB	Crystal structure of Thermus thermophilus transcription initiation complex with 5nt RNA Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*AP*GP*GP*GP*AP*TP*GP*CP*AP*G)-3'), DNA (5'-D(P*CP*TP*GP*CP*AP*TP*CP*CP*CP*TP*GP*AP*GP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Liu, Y, Ebright, R.H. Deposit date: 2021-04-28 Release date: 2022-02-02 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Structural and mechanistic basis of reiterative transcription initiation. Proc.Natl.Acad.Sci.USA, 119, 2022
7MLI	Crystal structure of Thermus thermophilus reiterative transcription complex with 5nt oligo-C RNA Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*CP*TP*AP*CP*GP*GP*AP*TP*G)-3'), DNA (5'-D(P*CP*AP*TP*CP*CP*GP*TP*AP*GP*GP*GP*CP*GP*GP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Liu, Y, Ebright, R.H. Deposit date: 2021-04-28 Release date: 2022-02-02 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Structural and mechanistic basis of reiterative transcription initiation. Proc.Natl.Acad.Sci.USA, 119, 2022
7MLJ	Crystal structure of Thermus thermophilus reiterative transcription complex with 4nt oligo-G RNA Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*GP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA (5'-D(P*CP*AP*TP*CP*CP*GP*TP*GP*CP*CP*CP*TP*GP*AP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Liu, Y, Ebright, R.H. Deposit date: 2021-04-28 Release date: 2022-02-02 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.75 Å) Cite: Structural and mechanistic basis of reiterative transcription initiation. Proc.Natl.Acad.Sci.USA, 119, 2022
2CQH	Solution structure of the RNA binding domain of IGF-II mRNA-binding protein 2 Descriptor: IGF-II mRNA-binding protein 2 isoform a Authors: Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2005-05-20 Release date: 2005-11-20 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structure of the RNA binding domain of IGF-II mRNA-binding protein 2 To be Published
3CCU	Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation G2482C Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ... Authors: Blaha, G, Gurel, G. Deposit date: 2008-02-26 Release date: 2008-05-20 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Mutations outside the anisomycin-binding site can make ribosomes drug-resistant. J.Mol.Biol., 379, 2008
3CCL	Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation U2535C. Density for Anisomycin is visible but not included in model. Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ... Authors: Blaha, G, Gurel, G. Deposit date: 2008-02-26 Release date: 2008-05-20 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Mutations outside the anisomycin-binding site can make ribosomes drug-resistant. J.Mol.Biol., 379, 2008
3CCV	Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation G2616A Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ... Authors: Blaha, G, Gurel, G. Deposit date: 2008-02-26 Release date: 2008-05-20 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Mutations outside the anisomycin-binding site can make ribosomes drug-resistant. J.Mol.Biol., 379, 2008
3CCE	Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation U2535A Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ... Authors: Blaha, G, Gurel, G. Deposit date: 2008-02-25 Release date: 2008-05-20 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Mutations outside the anisomycin-binding site can make ribosomes drug-resistant. J.Mol.Biol., 379, 2008

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