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7EH0	Thermus thermophilus RNA polymerase transcription initiation complex containing a template-strand purine at position TSS-2, UpA RNA primer and CMPcPP Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (27-MER), DNA (5'-D(*CP*C*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*AP*AP*AP*G)-3'), ... Authors: Li, L, Zhang, Y. Deposit date: 2021-03-27 Release date: 2021-07-14 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.808 Å) Cite: Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli . Proc.Natl.Acad.Sci.USA, 118, 2021
3OTB	Crystal structure of human tRNAHis guanylyltransferase (Thg1) - dGTP complex Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, TRIPHOSPHATE, ... Authors: Hyde, S.J, Eckenroth, B.E, Doublie, S. Deposit date: 2010-09-11 Release date: 2010-11-17 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.95 Å) Cite: tRNAHis guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases. Proc.Natl.Acad.Sci.USA, 107, 2010
7Y9Y	Structure of the Cas7-11-Csx29-guide RNA-target RNA (no PFS) complex Descriptor: CHAT domain-containing protein, CRISPR-associated RAMP family protein, RNA (27-MER), ... Authors: Kato, K, Okazaki, S, Ishikawa, J, Isayama, Y, Nishizawa, T, Nishimasu, H. Deposit date: 2022-06-26 Release date: 2022-11-09 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (2.77 Å) Cite: RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease. Science, 378, 2022
7Y9X	Structure of the Cas7-11-Csx29-guide RNA complex Descriptor: CHAT domain-containing protein, CRISPR-associated RAMP family protein, ZINC ION, ... Authors: Kato, K, Okazaki, S, Ishikawa, J, Isayama, Y, Nishizawa, T, Nishimasu, H. Deposit date: 2022-06-26 Release date: 2022-11-09 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (2.49 Å) Cite: RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease. Science, 378, 2022
3OTD	Crystal structure of human tRNAHis guanylyltransferase (Thg1)- NaI derivative Descriptor: IODIDE ION, tRNA(His) guanylyltransferase Authors: Hyde, S.J, Eckenroth, B.E, Doublie, S. Deposit date: 2010-09-11 Release date: 2010-11-17 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.28 Å) Cite: tRNAHis guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases. Proc.Natl.Acad.Sci.USA, 107, 2010
5NKX	HRSV M2-1 core domain, P3221 crystal form Descriptor: M2-1 Authors: Almeida Hernandez, Y, Josts, I, Molina, I.G, de Pray-Gay, G, Tidow, H. Deposit date: 2017-04-03 Release date: 2018-01-03 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.00008678 Å) Cite: Structure and stability of the Human respiratory syncytial virus M2-1RNA-binding core domain reveals a compact and cooperative folding unit. Acta Crystallogr F Struct Biol Commun, 74, 2018
4PUF	Complex between the Salmonella T3SS effector SlrP and its human target thioredoxin-1 Descriptor: E3 ubiquitin-protein ligase SlrP, Thioredoxin Authors: Zouhir, S, Bernal-Bayard, J, Cordero-Alba, M, Cardenal-Munoz, E, Guimaraes, B, Lazar, N, Ramos-Morales, F, Nessler, S. Deposit date: 2014-03-13 Release date: 2014-09-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.296 Å) Cite: The structure of the Slrp-Trx1 complex sheds light on the autoinhibition mechanism of the type III secretion system effectors of the NEL family. Biochem.J., 464, 2014
1TF6	CO-CRYSTAL STRUCTURE OF XENOPUS TFIIIA ZINC FINGER DOMAIN BOUND TO THE 5S RIBOSOMAL RNA GENE INTERNAL CONTROL REGION Descriptor: DNA (5'-D(*AP*CP*GP*GP*GP*CP*CP*TP*GP*GP*TP*TP*AP*GP*TP*AP*C P*CP*TP*GP*GP*AP* TP*GP*GP*GP*AP*GP*AP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*TP*CP*TP*CP*CP*CP*AP*TP*CP*CP*AP*GP*GP*T P*AP*CP*TP*AP*AP* CP*CP*AP*GP*GP*CP*CP*CP*G)-3'), PROTEIN (TRANSCRIPTION FACTOR IIIA), ... Authors: Nolte, R.T, Conlin, R.M, Harrison, S.C, Brown, R.S. Deposit date: 1998-03-02 Release date: 1998-07-10 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Differing roles for zinc fingers in DNA recognition: structure of a six-finger transcription factor IIIA complex. Proc.Natl.Acad.Sci.USA, 95, 1998
1XSU	Solution structure of E.coli RNase P RNA P4 stem, U69C/C70U mutation, complexed with cobalt (III) hexammine. Descriptor: COBALT HEXAMMINE(III), RNA (27-MER) Authors: Schmitz, M. Deposit date: 2004-10-20 Release date: 2004-12-28 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Change of RNase P RNA function by single base mutation correlates with perturbation of metal ion binding in P4 as determined by NMR spectroscopy Nucleic Acids Res., 32, 2004
1XST	Solution structure of E.coli RNase P RNA P4 stem, U69A mutation, complexed with cobalt (III) hexammine. Descriptor: COBALT HEXAMMINE(III), RNA (27-MER) Authors: Schmitz, M. Deposit date: 2004-10-20 Release date: 2004-12-28 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Change of RNase P RNA function by single base mutation correlates with perturbation of metal ion binding in P4 as determined by NMR spectroscopy Nucleic Acids Res., 32, 2004
5UI6	Solution NMR Structure of Lasso Peptide Acinetodin Descriptor: Acinetodin Authors: Bushin, L.B, Metelev, M, Severinov, K, Seyedsayamdost, M.R. Deposit date: 2017-01-12 Release date: 2017-02-08 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Acinetodin and Klebsidin, RNA Polymerase Targeting Lasso Peptides Produced by Human Isolates of Acinetobacter gyllenbergii and Klebsiella pneumoniae. ACS Chem. Biol., 12, 2017
5UI7	Solution NMR Structure of Lasso Peptide Klebsidin Descriptor: Klebsidin Authors: Bushin, L.B, Metelev, M, Severinov, K, Seyedsayamdost, M.R. Deposit date: 2017-01-13 Release date: 2017-02-08 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Acinetodin and Klebsidin, RNA Polymerase Targeting Lasso Peptides Produced by Human Isolates of Acinetobacter gyllenbergii and Klebsiella pneumoniae. ACS Chem. Biol., 12, 2017
5NOH	HRSV M2-1 core domain Descriptor: Transcription elongation factor M2-1 Authors: Josts, I, Almeida Hernandez, Y, Molina, I.G, de Prat-Gay, G, Tidow, H. Deposit date: 2017-04-12 Release date: 2018-01-03 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structure and stability of the Human respiratory syncytial virus M2-1RNA-binding core domain reveals a compact and cooperative folding unit. Acta Crystallogr F Struct Biol Commun, 74, 2018
5HCI	GPN-loop GTPase Npa3 in complex with GDP Descriptor: GLYCEROL, GPN-loop GTPase 1, GUANOSINE-5'-DIPHOSPHATE, ... Authors: Niesser, J, Wagner, F.R, Kostrewa, D, Muehlbacher, W, Cramer, P. Deposit date: 2016-01-04 Release date: 2016-01-20 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure of GPN-Loop GTPase Npa3 and Implications for RNA Polymerase II Assembly. Mol.Cell.Biol., 36, 2015
5HCN	GPN-loop GTPase Npa3 in complex with GMPPCP Descriptor: GLYCEROL, GPN-loop GTPase 1, LAURIC ACID, ... Authors: Niesser, J, Wagner, F.R, Kostrewa, D, Muehlbacher, W, Cramer, P. Deposit date: 2016-01-04 Release date: 2016-01-13 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure of GPN-Loop GTPase Npa3 and Implications for RNA Polymerase II Assembly. Mol.Cell.Biol., 36, 2015
1NGM	Crystal structure of a yeast Brf1-TBP-DNA ternary complex Descriptor: 5'-D(*AP*AP*AP*AP*AP*AP*CP*AP*TP*TP*TP*TP*TP*TP*TP*AP*TP*AP*G)-3', 5'-D(*CP*TP*AP*TP*AP*AP*AP*AP*AP*AP*AP*TP*GP*TP*TP*TP*TP*TP*T)-3', Transcription factor IIIB BRF1 subunit, ... Authors: Juo, Z.S, Kassavetis, G.A, Wang, J, Geiduschek, E.P, Sigler, P.B. Deposit date: 2002-12-17 Release date: 2003-03-25 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Crystal structure of a transcription factor IIIB core interface ternary complex Nature, 422, 2003
8B3G	C(N)RL4CSA-UVSSA-E2-ubiquitin complex. Descriptor: Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-8, ... Authors: Kokic, G, Cramer, P. Deposit date: 2022-09-16 Release date: 2024-09-04 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Structural basis for RNA polymerase II ubiquitylation and inactivation in transcription-coupled repair. Nat.Struct.Mol.Biol., 31, 2024
2VOD	Crystal structure of N-terminal domains of Human La protein complexed with RNA oligomer AUAUUUU Descriptor: 5'-R(*AP*UP*AP*UP*UP*UP*UP)-3', LUPUS LA PROTEIN Authors: Kotik-Kogan, O, Valentine, E.R, Sanfelice, D, Conte, M.R, Curry, S. Deposit date: 2008-02-15 Release date: 2008-05-06 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural Analysis Reveals Conformational Plasticity in the Recognition of RNA 3' Ends by the Human La Protein. Structure, 16, 2008
1AJF	SOLUTION STRUCTURE OF THE P5B STEM LOOP FROM A GROUP I INTRON COMPLEXED WITH COBALT (III) HEXAMMINE, NMR, MINIMIZED AVERAGE STRUCTURE Descriptor: COBALT HEXAMMINE(III), RNA (5'-R(*GP*AP*CP*AP*GP*GP*GP*GP*AP*AP*AP*CP*UP*UP*UP*GP*UP*C)-3') Authors: Kieft, J.S, Tinoco Junior, I. Deposit date: 1997-05-02 Release date: 1997-07-07 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Solution structure of a metal-binding site in the major groove of RNA complexed with cobalt (III) hexammine. Structure, 5, 1997
2VOO	Crystal structure of N-terminal domains of Human La protein complexed with RNA oligomer UUUUUUUU Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP)-3', LUPUS LA PROTEIN Authors: Kotik-Kogan, O, Valentine, E.R, Sanfelice, D, Conte, M.R, Curry, S. Deposit date: 2008-02-19 Release date: 2008-05-06 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural Analysis Reveals Conformational Plasticity in the Recognition of RNA 3' Ends by the Human La Protein. Structure, 16, 2008
1PLQ	CRYSTAL STRUCTURE OF THE EUKARYOTIC DNA POLYMERASE PROCESSIVITY FACTOR PCNA Descriptor: MERCURY (II) ION, PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) Authors: Krishna, T.S.R, Kong, X.-P, Gary, S, Burgers, P.M, Kuriyan, J. Deposit date: 1995-01-02 Release date: 1995-03-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA. Cell(Cambridge,Mass.), 79, 1994
1PLR	CRYSTAL STRUCTURE OF THE EUKARYOTIC DNA POLYMERASE PROCESSIVITY FACTOR PCNA Descriptor: PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) Authors: Krishna, T.S.R, Kong, X.-P, Gary, S, Burgers, P.M, Kuriyan, J. Deposit date: 1995-01-02 Release date: 1995-03-31 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3 Å) Cite: Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA. Cell(Cambridge,Mass.), 79, 1994
2VON	Crystal structure of N-terminal domains of Human La protein complexed with RNA oligomer AUAAUUU Descriptor: 5'-R(*AP*UP*AP*AP*UP*UP*UP)-3', LUPUS LA PROTEIN Authors: Kotik-Kogan, O, Valentine, E.R, Sanfelice, D, Conte, M.R, Curry, S. Deposit date: 2008-02-19 Release date: 2008-05-06 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural Analysis Reveals Conformational Plasticity in the Recognition of RNA 3' Ends by the Human La Protein. Structure, 16, 2008
2VOP	Crystal structure of N-terminal domains of Human La protein complexed with RNA oligomer AUUUU Descriptor: 5'-R(*AP*UP*UP*UP*UP)-3', LUPUS LA PROTEIN, SULFATE ION Authors: Kotik-Kogan, O, Valentine, E.R, Sanfelice, D, Conte, M.R, Curry, S. Deposit date: 2008-02-19 Release date: 2008-05-06 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural Analysis Reveals Conformational Plasticity in the Recognition of RNA 3' Ends by the Human La Protein. Structure, 16, 2008
8TDZ	16mer self-complementary duplex RNA with D:U pair sequence 2 Descriptor: COBALT HEXAMMINE(III), RNA Authors: Fang, Z, Jia, X, Szostak, J.W. Deposit date: 2023-07-05 Release date: 2024-06-12 Last modified: 2024-06-26 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Diaminopurine in Nonenzymatic RNA Template Copying. J.Am.Chem.Soc., 146, 2024

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