8H1A
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8H27
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2GBF
| rat dpp-IV with alkynyl cyanopyrrolidine #1 | Descriptor: | (1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-ETHYNYLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE, Dipeptidyl peptidase 4 | Authors: | Longenecker, K.L, Jakob, C.G, Fry, E.H, Wilk, S. | Deposit date: | 2006-03-10 | Release date: | 2006-07-04 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal Structures of DPP-IV (CD26) from Rat Kidney Exhibit Flexible Accommodation of Peptidase-Selective Inhibitors. Biochemistry, 45, 2006
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8H26
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8H0S
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8H0T
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8H1B
| Crystal structure of MnmM from S. aureus complexed with SAM and tRNA anti-codon stem loop (ASL) (1.55 A) | Descriptor: | RNA (5'-R(*AP*CP*GP*GP*AP*CP*UP*UP*UP*GP*AP*CP*UP*CP*CP*GP*U)-3'), S-ADENOSYLMETHIONINE, SODIUM ION, ... | Authors: | Kim, J, Cho, G, Lee, J. | Deposit date: | 2022-10-01 | Release date: | 2023-01-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Identification of a novel 5-aminomethyl-2-thiouridine methyltransferase in tRNA modification. Nucleic Acids Res., 51, 2023
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2G5T
| Crystal structure of human dipeptidyl peptidase IV (DPPIV) complexed with cyanopyrrolidine (C5-pro-pro) inhibitor 21ag | Descriptor: | 3-{[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHOXY}-4-CHLOROBENZOIC ACID, Dipeptidyl peptidase 4 | Authors: | Longenecker, K.L, Fry, E.H, Lake, M.R, Solomon, L.R, Pei, Z, Li, X. | Deposit date: | 2006-02-23 | Release date: | 2006-07-04 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Discovery, structure-activity relationship, and pharmacological evaluation of (5-substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as potent dipeptidyl peptidase IV inhibitors. J.Med.Chem., 49, 2006
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8JV3
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8JV4
| Structure of the SAR11 PotD in complex with DMSP | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-(dimethyl-lambda~4~-sulfanyl)propanoic acid, GLYCEROL, ... | Authors: | Ma, Q, Liu, C. | Deposit date: | 2023-06-27 | Release date: | 2024-07-03 | Method: | X-RAY DIFFRACTION (1.445 Å) | Cite: | Structure of the SAR11 PotD in complex with DMSP To Be Published
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8JV1
| Structure of the SAR11 PotD in complex with GABA | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, GAMMA-AMINO-BUTANOIC ACID, ... | Authors: | Ma, Q, Liu, C. | Deposit date: | 2023-06-27 | Release date: | 2024-07-03 | Method: | X-RAY DIFFRACTION (1.309 Å) | Cite: | Structure of the SAR11 PotD in complex with GABA To Be Published
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8T2B
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8JV2
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8T2A
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8T2O
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8T29
| Crystal structure of SCV PTE RNA in complex with Fab BL3-6 | Descriptor: | BL3-6 Fab heavy chain, BL3-6 Fab light chain, RNA (90-MER) | Authors: | Ojha, M, Koirala, D. | Deposit date: | 2023-06-05 | Release date: | 2024-01-10 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (3.13 Å) | Cite: | Structure of saguaro cactus virus 3' translational enhancer mimics 5' cap for eIF4E binding. Proc.Natl.Acad.Sci.USA, 121, 2024
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2GNI
| PKA fivefold mutant model of Rho-kinase with inhibitor Fasudil (HA1077) | Descriptor: | 5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE, cAMP-dependent protein kinase inhibitor alpha, cAMP-dependent protein kinase, ... | Authors: | Bonn, S, Herrero, S, Breitenlechner, C.B, Engh, R.A, Gassel, M, Bossemeyer, D. | Deposit date: | 2006-04-10 | Release date: | 2006-05-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity J.Biol.Chem., 281, 2006
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7VH4
| Crystal structure of oligoribonuclease of Escherichia coli | Descriptor: | ACETATE ION, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | Authors: | Badhwar, P, Taneja, B. | Deposit date: | 2021-09-20 | Release date: | 2022-09-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Three-dimensional structure of a mycobacterial oligoribonuclease reveals a unique C-terminal tail that stabilizes the homodimer. J.Biol.Chem., 298, 2022
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8JYU
| Acyl-ACP Synthetase structure bound to Decanoyl-AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, Acyl-acyl carrier protein synthetase, DECANOIC ACID, ... | Authors: | Huang, H, Chang, S, Huang, M, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | Deposit date: | 2023-07-03 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.19 Å) | Cite: | Acyl-ACP Synthetase structure bound to Decanoyl-AMP To Be Published
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8JYL
| Acyl-ACP Synthetase structure bound to C10-AMS | Descriptor: | Acyl-acyl carrier protein synthetase, MAGNESIUM ION, [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl N-decanoylsulfamate | Authors: | Huang, H, Chang, S, Huang, M, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | Deposit date: | 2023-07-03 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.33 Å) | Cite: | Acyl-ACP Synthetase structure bound to C10-AMS To Be Published
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2GVL
| Crystal Structure of Murine NMPRTase | Descriptor: | Nicotinamide phosphoribosyltransferase | Authors: | Khan, J.A, Tao, X, Tong, L. | Deposit date: | 2006-05-02 | Release date: | 2006-07-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents. Nat.Struct.Mol.Biol., 13, 2006
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8K4E
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8K3O
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8K2A
| Cryo-EM structure of the human 55S mitoribosome with Tigecycline | Descriptor: | 12S rRNA, 16S rRNA, 39S ribosomal protein L22, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2023-07-12 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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8K2B
| Cryo-EM structure of the human 39S mitoribosome with Tigecycline | Descriptor: | 16s rRNA, 39S ribosomal protein L22, mitochondrial, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2023-07-12 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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