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5HHE
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BU of 5hhe by Molmil
Human Beclin 1 coiled-coil domain
Descriptor: Beclin-1
Authors:Mei, Y, Sinha, S.
Deposit date:2016-01-10
Release date:2016-07-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Identification of BECN1 and ATG14 Coiled-Coil Interface Residues That Are Important for Starvation-Induced Autophagy.
Biochemistry, 55, 2016
4DYX
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BU of 4dyx by Molmil
Crystal Structure of the Cu-adduct of Human H-Ferritin variant 4His-delta C-star
Descriptor: CALCIUM ION, COPPER (II) ION, Ferritin heavy chain
Authors:Tezcan, F.A, Huard, D.J.E.
Deposit date:2012-02-29
Release date:2013-01-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Re-engineering protein interfaces yields copper-inducible ferritin cage assembly.
Nat.Chem.Biol., 9, 2013
3GOE
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BU of 3goe by Molmil
Molecular Mimicry of SUMO promotes DNA repair
Descriptor: CALCIUM ION, DNA repair protein rad60
Authors:Perry, J.J.P.
Deposit date:2009-03-19
Release date:2009-04-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:Molecular mimicry of SUMO promotes DNA repair.
Nat.Struct.Mol.Biol., 16, 2009
3H0M
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BU of 3h0m by Molmil
Structure of trna-dependent amidotransferase gatcab from aquifex aeolicus
Descriptor: Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, GLUTAMINE, Glutamyl-tRNA(Gln) amidotransferase subunit A, ...
Authors:Wu, J, Bu, W, Sheppard, K, Kitabatake, M, Soll, D, Smith, J.L.
Deposit date:2009-04-09
Release date:2009-07-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Insights into tRNA-Dependent Amidotransferase Evolution and Catalysis from the Structure of the Aquifex aeolicus Enzyme
J.Mol.Biol., 391, 2009
6A7E
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BU of 6a7e by Molmil
Human dihydrofolate reductase complexed with NADPH and BT2
Descriptor: 5-(4-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)-6-ethylpyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Vanichtanankul, J, Tarnchompoo, B, Chitnumsub, P, Kamchonwongpaisan, S, Yuthavong, Y.
Deposit date:2018-07-02
Release date:2019-04-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Hybrid Inhibitors of Malarial Dihydrofolate Reductase with Dual Binding Modes That Can Forestall Resistance.
ACS Med Chem Lett, 9, 2018
7CTH
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BU of 7cth by Molmil
Cryo-EM structure of dengue virus serotype 2 in complex with the scFv fragment of the broadly neutralizing antibody EDE1 C10
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Core protein, Single Chain Variable Fragment
Authors:Zhang, X, Sharma, A, Duquerroy, S, Zhou, Z.H, Rey, F.A.
Deposit date:2020-08-19
Release date:2021-12-01
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses.
Cell, 184, 2021
3GVG
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BU of 3gvg by Molmil
Crystal structure of Triosephosphate isomerase from Mycobacterium tuberculosis
Descriptor: GLYCEROL, Triosephosphate isomerase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-03-31
Release date:2009-04-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
5F98
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BU of 5f98 by Molmil
Crystal structure of RIG-I in complex with Cap-0 RNA
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Probable ATP-dependent RNA helicase DDX58, ...
Authors:Wang, C, Marcotrigiano, J, Miller, M, Jiang, F.
Deposit date:2015-12-09
Release date:2016-01-13
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.28 Å)
Cite:Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I.
Proc.Natl.Acad.Sci.USA, 113, 2016
6A2N
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BU of 6a2n by Molmil
Crystal structure of quadruple mutant (N51I+C59R+S108N+I164L) Plasmodium falciparum DHFR-TS complexed with BT2, NADPH, and dUMP
Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-(4-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)-6-ethylpyrimidine-2,4-diamine, Bifunctional dihydrofolate reductase-thymidylate synthase, ...
Authors:Chitnumsub, P, Jaruwat, A, Tarnchampoo, B, Yuthavong, Y.
Deposit date:2018-06-12
Release date:2019-04-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Hybrid Inhibitors of Malarial Dihydrofolate Reductase with Dual Binding Modes That Can Forestall Resistance.
ACS Med Chem Lett, 9, 2018
3GWC
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BU of 3gwc by Molmil
Crystal structure of Mycobacterium tuberculosis thymidylate synthase X bound to FdUMP and FAD
Descriptor: 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-03-31
Release date:2009-04-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
6A6G
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BU of 6a6g by Molmil
Crystal structure of thermostable FiSufS-SufU complex from thermophilic Fervidobacterium Islandicum AW-1
Descriptor: Cysteine desulfurase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Dhanasingh, I, Jin, H.S, Lee, D.W, Lee, S.H.
Deposit date:2018-06-27
Release date:2019-10-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:The sulfur formation system mediating extracellular cysteine-cystine recycling in Fervidobacterium islandicum AW-1 is associated with keratin degradation.
Microb Biotechnol, 2020
3ETZ
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BU of 3etz by Molmil
Crystal structure of bacterial adhesin FadA L76A mutant
Descriptor: Adhesin A
Authors:Nithianantham, S, Xu, M, Wu, N, Shoham, M, Han, Y.W.
Deposit date:2008-10-08
Release date:2008-12-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of FadA Adhesin from Fusobacterium nucleatum Reveals a Novel Oligomerization Motif, the Leucine Chain.
J.Biol.Chem., 284, 2009
2PUY
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BU of 2puy by Molmil
Crystal Structure of the BHC80 PHD finger
Descriptor: Histone H3, PHD finger protein 21A, ZINC ION
Authors:Horton, J.R, Cheng, X, Collins, R.E.
Deposit date:2007-05-09
Release date:2007-08-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression.
Nature, 448, 2007
6A7C
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BU of 6a7c by Molmil
Human dihydrofolate reductase complexed with NADPH and BT1
Descriptor: 5-(3-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)-6-ethylpyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Vanichtanankul, J, Tarnchompoo, B, Chitnumsub, P, Kamchonwongpaisan, S, Yuthavong, Y.
Deposit date:2018-07-02
Release date:2019-04-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Hybrid Inhibitors of Malarial Dihydrofolate Reductase with Dual Binding Modes That Can Forestall Resistance.
ACS Med Chem Lett, 9, 2018
3F39
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BU of 3f39 by Molmil
Apoferritin: complex with phenol
Descriptor: CADMIUM ION, Ferritin light chain, PHENOL, ...
Authors:Vedula, L.S, Economou, N.J, Rossi, M.J, Eckenhoff, R.G, Loll, P.J.
Deposit date:2008-10-30
Release date:2009-07-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A unitary anesthetic binding site at high resolution.
J.Biol.Chem., 284, 2009
5H5U
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BU of 5h5u by Molmil
Mechanistic insights into the alternative translation termination by ArfA and RF2
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Ma, C, Kurita, D, Li, N, Chen, Y, Himeno, H, Gao, N.
Deposit date:2016-11-09
Release date:2017-01-25
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Mechanistic insights into the alternative translation termination by ArfA and RF2
Nature, 541, 2017
3NGV
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BU of 3ngv by Molmil
Crystal structure of AnSt-D7L1
Descriptor: D7 protein, GLYCEROL, SULFATE ION
Authors:Andersen, J.F, Alvarenga, P.H, Francischetti, I.M, Ribeiro, J.M, Calvo, E.
Deposit date:2010-06-13
Release date:2010-12-29
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:The function and three-dimensional structure of a thromboxane a(2)/cysteinyl leukotriene-binding protein from the saliva of a mosquito vector of the malaria parasite.
Plos Biol., 8, 2010
3F36
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BU of 3f36 by Molmil
Apoferritin: complex with 2-isopropylphenol
Descriptor: 2-(1-methylethyl)phenol, CADMIUM ION, Ferritin light chain, ...
Authors:Vedula, L.S, Economou, N.J, Rossi, M.J, Eckenhoff, R.G, Loll, P.J.
Deposit date:2008-10-30
Release date:2009-07-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A unitary anesthetic binding site at high resolution.
J.Biol.Chem., 284, 2009
2PLJ
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BU of 2plj by Molmil
Crystal structure of lysine/ornithine decarboxylase complexed with putrescine from Vibrio vulnificus
Descriptor: (4-{[(4-AMINOBUTYL)AMINO]METHYL}-5-HYDROXY-6-METHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, MAGNESIUM ION, lysine/ornithine decarboxylase
Authors:Lee, J, Goldsmith, E.J, Phillips, M.A.
Deposit date:2007-04-19
Release date:2007-07-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Phylogenetic diversity and the structural basis of substrate specificity in the beta/alpha-barrel fold basic amino acid decarboxylases.
J.Biol.Chem., 282, 2007
5ZV3
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BU of 5zv3 by Molmil
Crystal structure of human anti-tau antibody CBTAU-28.1 in complex with its tau peptide
Descriptor: Heavy chain of antibody CBTAU28.1, Light chain (kappa) of antibody CBTAU28.1, Peptide from Microtubule-associated protein tau
Authors:Zhang, H, Wilson, I.A.
Deposit date:2018-05-09
Release date:2018-06-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.093 Å)
Cite:A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities.
Acta Neuropathol Commun, 6, 2018
3PUF
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BU of 3puf by Molmil
Crystal structure of human RNase H2 complex
Descriptor: Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C
Authors:Figiel, M, Chon, H, Cerritelli, S.M, Cybulska, M, Crouch, R.J, Nowotny, M.
Deposit date:2010-12-04
Release date:2010-12-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The structural and biochemical characterization of human RNase H2 complex reveals the molecular basis for substrate recognition and Aicardi-Goutieres syndrome defects.
J.Biol.Chem., 286, 2011
4F1H
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BU of 4f1h by Molmil
Crystal structure of TDP2 from Danio rerio complexed with a single strand DNA
Descriptor: DNA (5'-D(P*TP*GP*CP*AP*G)-3'), GLYCEROL, MAGNESIUM ION, ...
Authors:Shi, K, Kurahashi, K, Aihara, H.
Deposit date:2012-05-06
Release date:2012-10-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.662 Å)
Cite:Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2.
Nat.Struct.Mol.Biol., 19, 2012
3FBM
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BU of 3fbm by Molmil
D431N Mutant VP2 Protein of Infectious Bursal Disease Virus; Derived T=1 Particles
Descriptor: CALCIUM ION, Polyprotein
Authors:Irigoyen, N, Garriga, D, Navarro, A, Verdaguer, N, Rodriguez, J.F, Caston, J.R.
Deposit date:2008-11-19
Release date:2009-01-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Autoproteolytic Activity Derived from the Infectious Bursal Disease Virus Capsid Protein
J.Biol.Chem., 284, 2009
3FC3
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BU of 3fc3 by Molmil
Crystal structure of the beta-beta-alpha-Me type II restriction endonuclease Hpy99I
Descriptor: 5'-(*DCP*DTP*DCP*DGP*DAP*DCP*DGP*DTP*DAP*DGP*DA)-3', 5'-(*DTP*DAP*DCP*DGP*DTP*DCP*DGP*DAP*DGP*DTP*DC)-3', Restriction endonuclease Hpy99I, ...
Authors:Sokolowska, M, Czapinska, H, Bochtler, M.
Deposit date:2008-11-21
Release date:2009-03-31
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of the beta beta alpha-Me type II restriction endonuclease Hpy99I with target DNA.
Nucleic Acids Res., 37, 2009
4F47
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BU of 4f47 by Molmil
The Structure of Enoyl-CoA hydratase EchA19 from Mycobacterium marinum
Descriptor: Enoyl-CoA hydratase EchA19
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-05-10
Release date:2012-05-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015

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数据于2024-07-17公开中

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