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4NU8
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BU of 4nu8 by Molmil
Crystal structure of O-acetylserine sulfhydrylase from Haemophilus influenzae in complex with high affinity inhibitory peptide from serine acetyl transferase of Salmonella typhimurium at 2.0 A
Descriptor: Cysteine synthase, GLYCEROL, Peptide from Serine acetyltransferase
Authors:Ekka, M.K, Kaushik, A, Singh, A.K, Kumaran, S.
Deposit date:2013-12-03
Release date:2014-12-03
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Crystal structure of O-acetylserine sulfhydrylase from Haemophilus influenzae in complex with high affinity inhibitory peptide from serine acetyl transferase of Salmonella Typhimurium at 2.0 A
To be Published
4O5C
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BU of 4o5c by Molmil
Structure of human DNA polymerase complexed with N7-MG as the template base in a 1-nucleotide gapped DNA
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*(FMG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2013-12-19
Release date:2014-07-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.363 Å)
Cite:Transition-state destabilization reveals how human DNA polymerase beta proceeds across the chemically unstable lesion N7-methylguanine.
Nucleic Acids Res., 42, 2014
3BX2
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BU of 3bx2 by Molmil
Puf4 RNA binding domain bound to HO endonuclease RNA 3' UTR recognition sequence
Descriptor: HO endonuclease 3' UTR binding sequence, Protein PUF4, SODIUM ION, ...
Authors:Miller, M.T, Higgin, J.J, Hall, T.M.T.
Deposit date:2008-01-11
Release date:2008-03-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Basis of altered RNA-binding specificity by PUF proteins revealed by crystal structures of yeast Puf4p
Nat.Struct.Mol.Biol., 15, 2008
4F63
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BU of 4f63 by Molmil
Crystal structure of Human Fibroblast Growth Factor Receptor 1 Kinase domain in complex with compound 1
Descriptor: 1,2-ETHANEDIOL, 5-bromo-N~4~-(3-methyl-1H-pyrazol-5-yl)-N~2~-[2-(pyridin-3-yl)ethyl]pyrimidine-2,4-diamine, Fibroblast growth factor receptor 1
Authors:Norman, R.A, Breed, J, Ogg, D.
Deposit date:2012-05-14
Release date:2012-06-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Protein-Ligand Crystal Structures Can Guide the Design of Selective Inhibitors of the FGFR Tyrosine Kinase.
J.Med.Chem., 55, 2012
4F64
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BU of 4f64 by Molmil
Crystal structure of Human Fibroblast Growth Factor Receptor 1 Kinase domain in complex with compound 6
Descriptor: 1,2-ETHANEDIOL, 5-bromo-N~4~-[3-(3-methoxypropyl)-1H-pyrazol-5-yl]-N~2~-[(3-methyl-1,2-oxazol-5-yl)methyl]pyrimidine-2,4-diamine, Fibroblast growth factor receptor 1, ...
Authors:Norman, R.A, Breed, J, Ogg, D.
Deposit date:2012-05-14
Release date:2012-06-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Protein-Ligand Crystal Structures Can Guide the Design of Selective Inhibitors of the FGFR Tyrosine Kinase.
J.Med.Chem., 55, 2012
4NXB
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BU of 4nxb by Molmil
Crystal structure of iLOV-I486(2LT) at pH 7.0
Descriptor: FLAVIN MONONUCLEOTIDE, Phototropin-2
Authors:Wang, J, Li, J, Liu, X.
Deposit date:2013-12-09
Release date:2014-09-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.561 Å)
Cite:Significant expansion of fluorescent protein sensing ability through the genetic incorporation of superior photo-induced electron-transfer quenchers.
J.Am.Chem.Soc., 136, 2014
4NXL
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BU of 4nxl by Molmil
Dibenzothiophene monooxygenase (DszC) from Rhodococcus erythropolis
Descriptor: DszC
Authors:Zhang, L, Duan, X, Li, X, Rao, Z.
Deposit date:2013-12-09
Release date:2014-07-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into the stabilization of active, tetrameric DszC by its C-terminus.
Proteins, 82, 2014
4FAZ
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BU of 4faz by Molmil
Kinetic and structural characterization of the 4-oxalocrotonate tautomerase isozymes from Methylibium petroleiphilum
Descriptor: 4-oxalocrotonate isomerase protein, SULFATE ION
Authors:Terrell, C.R, Hoffman, D.W, Whitman, C.P.
Deposit date:2012-05-22
Release date:2013-06-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Structural and kinetic characterization of two 4-oxalocrotonate tautomerases in Methylibium petroleiphilum strain PM1.
Arch.Biochem.Biophys., 537, 2013
4O21
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BU of 4o21 by Molmil
Product complex of metal-free PKAc, ATP-gamma-S and SP20.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Thio-phosphorylated peptide pSP20, cAMP-dependent protein kinase catalytic subunit alpha
Authors:Das, A, Kovalevsky, A.Y, Gerlits, O, Langan, P, Heller, W.T, Keshwani, M, Taylor, S.
Deposit date:2013-12-16
Release date:2014-05-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Metal-Free cAMP-Dependent Protein Kinase Can Catalyze Phosphoryl Transfer.
Biochemistry, 53, 2014
3BX3
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BU of 3bx3 by Molmil
Puf4 T650C/C724R Mutant bound to Cox17 RNA 3' UTR recognition sequence
Descriptor: COX17 RNA target sequence, Protein PUF4, SULFATE ION
Authors:Miller, M.T, Higgin, J.J, Hall, T.M.T.
Deposit date:2008-01-11
Release date:2008-03-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Basis of altered RNA-binding specificity by PUF proteins revealed by crystal structures of yeast Puf4p
Nat.Struct.Mol.Biol., 15, 2008
3BZK
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BU of 3bzk by Molmil
Crystal Structure of the Tex protein from Pseudomonas aeruginosa, crystal form 2
Descriptor: Tex
Authors:Johnson, S.J, Close, D, Hill, C.P.
Deposit date:2008-01-18
Release date:2008-04-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure and RNA binding of the Tex protein from Pseudomonas aeruginosa.
J.Mol.Biol., 377, 2008
3GV6
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BU of 3gv6 by Molmil
Crystal Structure of human chromobox homolog 6 (CBX6) with H3K9 peptide
Descriptor: Chromobox protein homolog 6, Histone H3K9me3 peptide
Authors:Dong, A, Amaya, M.F, Li, Z, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC)
Deposit date:2009-03-30
Release date:2009-04-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Recognition and specificity determinants of the human cbx chromodomains.
J.Biol.Chem., 286, 2011
4O72
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BU of 4o72 by Molmil
Crystal structure of the first bromodomain of human BRD4 in complex with NU7441
Descriptor: 1,2-ETHANEDIOL, 8-(dibenzo[b,d]thiophen-4-yl)-2-(morpholin-4-yl)-4H-chromen-4-one, Bromodomain-containing protein 4, ...
Authors:Zhu, J.-Y, Ember, S.W, Watts, C, Schonbrunn, E.
Deposit date:2013-12-24
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Acetyl-lysine Binding Site of Bromodomain-Containing Protein 4 (BRD4) Interacts with Diverse Kinase Inhibitors.
Acs Chem.Biol., 9, 2014
4FFJ
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BU of 4ffj by Molmil
The crystal structure of spDHBPs from S.pneumoniae
Descriptor: GLYCEROL, Riboflavin biosynthesis protein ribBA, SULFATE ION
Authors:Wang, D.
Deposit date:2012-06-01
Release date:2013-07-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The crystal structure of SpDHBPs from S. pneumoniae
To be Published
4F0K
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BU of 4f0k by Molmil
UNACTIVATED RUBISCO with MAGNESIUM AND CARBON DIOXIDE BOUND
Descriptor: CARBON DIOXIDE, CHLORIDE ION, GLYCEROL, ...
Authors:Stec, B.
Deposit date:2012-05-04
Release date:2012-11-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural mechanism of RuBisCO activation by carbamylation of the active site lysine.
Proc.Natl.Acad.Sci.USA, 109, 2012
4OI6
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BU of 4oi6 by Molmil
Crystal structure analysis of nickel-bound form SCO4226 from Streptomyces coelicolor A3(2)
Descriptor: CITRIC ACID, NICKEL (II) ION, Nickel responsive protein
Authors:Lu, M, Jiang, Y.L, Wang, S, Cheng, W, Zhang, R.G, Virolle, M.J, Chen, Y, Zhou, C.Z.
Deposit date:2014-01-18
Release date:2014-09-10
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Streptomyces coelicolor SCO4226 Is a Nickel Binding Protein.
Plos One, 9, 2014
4FQO
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BU of 4fqo by Molmil
Crystal Structure of Calcium-Loaded S100B Bound to SBi4211
Descriptor: 4,4'-[heptane-1,7-diylbis(oxy)]dibenzenecarboximidamide, CALCIUM ION, Protein S100-B
Authors:McKnight, L.E, Raman, E.P, Bezawada, P, Kudrimoti, S, Wilder, P.T, Hartman, K.G, Toth, E.A, Coop, A, MacKerrell, A.D, Weber, D.J.
Deposit date:2012-06-25
Release date:2012-10-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure-Based Discovery of a Novel Pentamidine-Related Inhibitor of the Calcium-Binding Protein S100B.
ACS Med Chem Lett, 3, 2012
4V0Z
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BU of 4v0z by Molmil
o-nitrophenyl Cellobioside as an Active Site Probe for Family 7 Cellobiohydrolases
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CELLOBIOHYDROLASE CEL7A, COBALT (II) ION, ...
Authors:Nutt, A, Momeni, M.H, Stahlberg, J.
Deposit date:2014-09-19
Release date:2015-09-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Enzyme kinetics by GH7 cellobiohydrolases on chromogenic substrates is dictated by non-productive binding: insights from crystal structures and MD simulation.
Febs J., 2022
4V1W
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BU of 4v1w by Molmil
3D structure of horse spleen apoferritin determined by electron cryomicroscopy
Descriptor: FERRITIN LIGHT CHAIN
Authors:Russo, C.J, Passmore, L.A.
Deposit date:2014-10-02
Release date:2014-12-10
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Electron Microscopy. Ultrastable Gold Substrates for Electron Cryomicroscopy.
Science, 346, 2014
7Y74
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BU of 7y74 by Molmil
Apostichopus japonicus ferritin mutant-D129A/E132A
Descriptor: CADMIUM ION, FE (III) ION, Ferritin
Authors:Wu, Y, Ming, T.H, Su, X.R.
Deposit date:2022-06-21
Release date:2023-07-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Apostichopus japonicus ferritin mutant-D129A/E132A
To Be Published
7YA3
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BU of 7ya3 by Molmil
Formate dehydrogenase from Novosphingobium sp. AP12 with NADP and Azide
Descriptor: AZIDE ION, Formate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Kim, S, Kim, K.-J.
Deposit date:2022-06-27
Release date:2023-07-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Dual cofactor specific formate dehydrogenase from Novosphingobium sp. AP12 with high activity.
To Be Published
6X1H
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BU of 6x1h by Molmil
Crystal structure of a guanine nucleotide exchange factor (GEF) domain from the Orientia tsutsugamushi protein OtDUB
Descriptor: NICKEL (II) ION, ULP_PROTEASE domain-containing protein
Authors:Lim, C.S, Xiong, Y.
Deposit date:2020-05-18
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Crystal structure of a guanine nucleotide exchange factor encoded by the scrub typhus pathogen Orientia tsutsugamushi .
Proc.Natl.Acad.Sci.USA, 117, 2020
6X2D
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BU of 6x2d by Molmil
Crystal Structure of DNase I Domain of Ribonuclease E from Vibrio cholerae
Descriptor: IODIDE ION, Ribonuclease E
Authors:Minasov, G, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Wiersum, G, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-05-20
Release date:2020-06-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of DNase I Domain of Ribonuclease E from Vibrio cholerae.
To Be Published
4V5V
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BU of 4v5v by Molmil
Structure of respiratory syncytial virus nucleocapsid protein, P1 crystal form
Descriptor: RESPIRATORY SYNCYTIAL VIRUS NUCLEOCAPSID PROTEIN, RNA
Authors:El Omari, K, Dhaliwal, B, Ren, J, Abrescia, N.G.A, Lockyer, M, Powell, K.L, Hawkins, A.R, Stammers, D.K.
Deposit date:2011-05-04
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structures of Respiratory Syncytial Virus Nucleocapsid Protein from Two Crystal Forms: Details of Potential Packing Interactions in the Native Helical Form.
Acta Crystallogr.,Sect.F, 67, 2011
6WDW
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BU of 6wdw by Molmil
Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with Dimethylaminoethylindole Phenylhydroxamate Inhibitor
Descriptor: 4-({3-[2-(dimethylamino)ethyl]-1H-indol-1-yl}methyl)-N-hydroxybenzamide, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Herbst-Gervasoni, C.J, Christianson, D.W.
Deposit date:2020-04-01
Release date:2020-07-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis for the Selective Inhibition of HDAC10, the Cytosolic Polyamine Deacetylase.
Acs Chem.Biol., 15, 2020

224004

数据于2024-08-21公开中

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