4MJH
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4I0O
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4I0K
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![BU of 4i0k by Molmil](/molmil-images/mine/4i0k) | Crystal structure of murine B7-H3 extracellular domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CD276 antigen, SULFATE ION, ... | Authors: | Vigdorovich, V, Ramagopal, U, Bonanno, J.B, Toro, R, Nathenson, S.G, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN) | Deposit date: | 2012-11-16 | Release date: | 2012-12-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.97 Å) | Cite: | Structure and T cell inhibition properties of B7 family member, B7-H3. Structure, 21, 2013
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4MK8
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![BU of 4mk8 by Molmil](/molmil-images/mine/4mk8) | Hepatitis C Virus polymerase NS5B genotype 1b (BK) in complex with inhibitor 4 (N-(4-{2-[3-tert-butyl-2-methoxy-5-(2-oxo-1,2-dihydropyridin-3-yl)phenyl]ethyl}phenyl)methanesulfonamide) | Descriptor: | DIMETHYL SULFOXIDE, GLYCEROL, N-(4-{2-[3-tert-butyl-2-methoxy-5-(2-oxo-1,2-dihydropyridin-3-yl)phenyl]ethyl}phenyl)methanesulfonamide, ... | Authors: | Harris, S.F, Wong, A. | Deposit date: | 2013-09-04 | Release date: | 2013-10-09 | Last modified: | 2014-01-15 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Discovery of a Novel Series of Potent Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B. J.Med.Chem., 56, 2013
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3EI4
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![BU of 3ei4 by Molmil](/molmil-images/mine/3ei4) | Structure of the hsDDB1-hsDDB2 complex | Descriptor: | DNA damage-binding protein 1, DNA damage-binding protein 2 | Authors: | Scrima, A, Pavletich, N.P, Thoma, N.H. | Deposit date: | 2008-09-15 | Release date: | 2009-01-20 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex. Cell(Cambridge,Mass.), 135, 2008
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4I2W
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4I5D
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![BU of 4i5d by Molmil](/molmil-images/mine/4i5d) | Crystal structure of Ralstonia sp. alcohol dehydrogenase in its apo form | Descriptor: | Alclohol dehydrogenase/short-chain dehydrogenase, SULFATE ION | Authors: | Jarasch, A, Lerchner, A, Meining, W, Schiefner, A, Skerra, A. | Deposit date: | 2012-11-28 | Release date: | 2013-06-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystallographic analysis and structure-guided engineering of NADPH-dependent Ralstonia sp. Alcohol dehydrogenase toward NADH cosubstrate specificity. Biotechnol.Bioeng., 110, 2013
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4I44
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4MOV
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![BU of 4mov by Molmil](/molmil-images/mine/4mov) | 1.45 A Resolution Crystal Structure of Protein Phosphatase 1 | Descriptor: | CHLORIDE ION, MANGANESE (II) ION, PHOSPHATE ION, ... | Authors: | Choy, M.S, Peti, W, Page, R. | Deposit date: | 2013-09-12 | Release date: | 2014-03-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.4503 Å) | Cite: | Understanding the antagonism of retinoblastoma protein dephosphorylation by PNUTS provides insights into the PP1 regulatory code. Proc.Natl.Acad.Sci.USA, 111, 2014
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4MP4
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![BU of 4mp4 by Molmil](/molmil-images/mine/4mp4) | Crystal structure of a glutathione transferase family member from Acinetobacter baumannii, Target EFI-501785, apo structure | Descriptor: | Glutathione S-transferase, SULFATE ION | Authors: | Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Armstrong, R.N, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2013-09-12 | Release date: | 2013-10-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.498 Å) | Cite: | Crystal structure of a glutathione transferase family member from Acinetobacter baumannii, Target EFI-501785, apo structure To be Published
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3O60
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3O6C
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![BU of 3o6c by Molmil](/molmil-images/mine/3o6c) | Pyridoxal phosphate biosynthetic protein PdxJ from Campylobacter jejuni | Descriptor: | PHOSPHATE ION, Pyridoxine 5'-phosphate synthase | Authors: | Osipiuk, J, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2010-07-28 | Release date: | 2010-08-11 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Pyridoxal phosphate biosynthetic protein PdxJ from Campylobacter jejuni. To be Published
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3ETB
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![BU of 3etb by Molmil](/molmil-images/mine/3etb) | Crystal structure of the engineered neutralizing antibody M18 complexed with anthrax protective antigen domain 4 | Descriptor: | Anthrax Protective Antigen, Antibody M18 light chain and antibody M18 heavy chain linked with a synthetic (GGGGS)4 linker | Authors: | Monzingo, A.F, Leysath, C.E, Barnett, J, Iverson, B.L, Georgiou, G, Robertus, J.D. | Deposit date: | 2008-10-07 | Release date: | 2009-04-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Crystal structure of the engineered neutralizing antibody M18 complexed to domain 4 of the anthrax protective antigen. J.Mol.Biol., 387, 2009
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4I9O
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![BU of 4i9o by Molmil](/molmil-images/mine/4i9o) | Crystal Structure of GACKIX L664C Tethered to 1-10 | Descriptor: | 1,2-ETHANEDIOL, 1-{4-[4-chloro-3-(trifluoromethyl)phenyl]-4-hydroxypiperidin-1-yl}-3-sulfanylpropan-1-one, CREB-binding protein | Authors: | Wang, N, Meagher, J.L, Stuckey, J.A, Mapp, A.K. | Deposit date: | 2012-12-05 | Release date: | 2013-03-06 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Ordering a dynamic protein via a small-molecule stabilizer. J.Am.Chem.Soc., 135, 2013
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4MP8
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![BU of 4mp8 by Molmil](/molmil-images/mine/4mp8) | Staphyloferrin B precursor biosynthetic enzyme SbnB bound to malonate and NAD+ | Descriptor: | MALONATE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative ornithine cyclodeaminase | Authors: | Grigg, J.C, Kobylarz, M.J, Rai, D.K, Murphy, M.E.P. | Deposit date: | 2013-09-12 | Release date: | 2014-03-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Synthesis of L-2,3-diaminopropionic Acid, a siderophore and antibiotic precursor. Chem.Biol., 21, 2014
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3O6J
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![BU of 3o6j by Molmil](/molmil-images/mine/3o6j) | Crystal Structure of 4-Chlorocatechol Dioxygenase from Rhodococcus opacus 1CP in complex with hydroxyquinol | Descriptor: | (2R)-3-(PHOSPHONOOXY)-2-(TETRADECANOYLOXY)PROPYL PALMITATE, CHLORIDE ION, Chlorocatechol 1,2-dioxygenase, ... | Authors: | Ferraroni, M, Briganti, F, Kolomitseva, M, Golovleva, L. | Deposit date: | 2010-07-29 | Release date: | 2011-08-17 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | X-ray structures of 4-chlorocatechol 1,2-dioxygenase adducts with substituted catechols: new perspectives in the molecular basis of intradiol ring cleaving dioxygenases specificity. J. Struct. Biol., 181, 2013
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4MQG
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4I9Y
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![BU of 4i9y by Molmil](/molmil-images/mine/4i9y) | Structure of the C-terminal domain of Nup358 | Descriptor: | CHLORIDE ION, E3 SUMO-protein ligase RanBP2, GLYCEROL, ... | Authors: | Lin, D.H, Zimmermann, S, Stuwe, T, Stuwe, E, Hoelz, A. | Deposit date: | 2012-12-05 | Release date: | 2013-01-30 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural and Functional Analysis of the C-Terminal Domain of Nup358/RanBP2. J.Mol.Biol., 425, 2013
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4I63
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![BU of 4i63 by Molmil](/molmil-images/mine/4i63) | Crystal Structure of E-R ClpX Hexamer | Descriptor: | ATP-dependent Clp protease ATP-binding subunit ClpX, SULFATE ION | Authors: | Glynn, S.E, Nager, A.R, Stinson, B.S, Schmitz, K.R, Baker, T.A, Sauer, R.T. | Deposit date: | 2012-11-29 | Release date: | 2013-05-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (5.709 Å) | Cite: | Nucleotide Binding and Conformational Switching in the Hexameric Ring of a AAA+ Machine. Cell(Cambridge,Mass.), 153, 2013
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4I7J
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![BU of 4i7j by Molmil](/molmil-images/mine/4i7j) | T4 Lysozyme L99A/M102H with benzene bound | Descriptor: | 2-HYDROXYETHYL DISULFIDE, ACETATE ION, BENZENE, ... | Authors: | Merski, M, Shoichet, B.K. | Deposit date: | 2012-11-30 | Release date: | 2013-03-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | The impact of introducing a histidine into an apolar cavity site on docking and ligand recognition. J.Med.Chem., 56, 2013
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4MRM
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![BU of 4mrm by Molmil](/molmil-images/mine/4mrm) | Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist phaclofen | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, ... | Authors: | Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R. | Deposit date: | 2013-09-17 | Release date: | 2013-12-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Structural mechanism of ligand activation in human GABA(B) receptor. Nature, 504, 2013
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4HN8
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![BU of 4hn8 by Molmil](/molmil-images/mine/4hn8) | Crystal structure of a putative D-glucarate dehydratase from Pseudomonas mendocina ymp | Descriptor: | D-glucarate dehydratase, GLYCEROL | Authors: | Hegde, R.P, Toro, R, Burley, S.K, Almo, S.C, Ramagopal, U.A, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2012-10-19 | Release date: | 2012-11-07 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a putative D-glucarate dehydratase from Pseudomonas mendocina ymp To be published
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4HOE
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![BU of 4hoe by Molmil](/molmil-images/mine/4hoe) | Candida albicans dihydrofolate reductase complexed with NADPH and 5-[3-(2,5-dimethoxy-4-phenylphenyl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine (UCP111E) | Descriptor: | 5-[3-(2,5-dimethoxy-4-phenylphenyl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine, Dihydrofolate reductase, GLYCEROL, ... | Authors: | Paulsen, J.L, Anderson, A.C. | Deposit date: | 2012-10-22 | Release date: | 2014-03-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Propargyl-Linked Antifolates are Dual Inhibitors of Candida albicans and Candida glabrata. J.Med.Chem., 57, 2014
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4MT5
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![BU of 4mt5 by Molmil](/molmil-images/mine/4mt5) | Crystal structure of Mub-RV | Descriptor: | Mucus binding proteinn | Authors: | Etzold, S, Juge, N, Hemmings, A.M. | Deposit date: | 2013-09-19 | Release date: | 2014-08-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for adaptation of lactobacilli to gastrointestinal mucus. ENVIRON.MICROBIOL., 16, 2014
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4HOO
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![BU of 4hoo by Molmil](/molmil-images/mine/4hoo) | Crystal structure of human JMJD2D/KDM4D apoenzyme | Descriptor: | ACETATE ION, Lysine-specific demethylase 4D, NICKEL (II) ION, ... | Authors: | Krishnan, S, Trievel, R.C. | Deposit date: | 2012-10-22 | Release date: | 2012-11-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.495 Å) | Cite: | Structural and Functional Analysis of JMJD2D Reveals Molecular Basis for Site-Specific Demethylation among JMJD2 Demethylases. Structure, 21, 2013
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