6CQF
 
 | | Crystal structure of HPK1 in complex an inhibitor G1858 | | Descriptor: | Mitogen-activated protein kinase kinase kinase kinase 1, N-{2-(3,3-difluoropyrrolidin-1-yl)-6-[(3R)-pyrrolidin-3-yl]pyrimidin-4-yl}-1-(propan-2-yl)-1H-pyrazolo[4,3-c]pyridin-6-amine | | Authors: | Wu, P, Lehoux, I, Mortara, K, Franke, Y, Chan, B.K, Wang, W. | | Deposit date: | 2018-03-15 | | Release date: | 2018-12-19 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.246 Å) | | Cite: | Hematopoietic Progenitor Kinase-1 Structure in a Domain-Swapped Dimer.
Structure, 27, 2019
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1ZB7
 | | Crystal Structure of Botulinum Neurotoxin Type G Light Chain | | Descriptor: | CITRATE ANION, ZINC ION, neurotoxin | | Authors: | Arndt, J.W, Yu, W, Bi, F, Stevens, R.C. | | Deposit date: | 2005-04-07 | | Release date: | 2005-07-05 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Crystal structure of botulinum neurotoxin type g light chain: serotype divergence in substrate recognition
Biochemistry, 44, 2005
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5GVB
 | | SepB domain of human AND-1 | | Descriptor: | WD repeat and HMG-box DNA-binding protein 1 | | Authors: | Guan, C.C, Li, J. | | Deposit date: | 2016-09-05 | | Release date: | 2017-04-19 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | The structure and polymerase-recognition mechanism of the crucial adaptor protein AND-1 in the human replisome.
J. Biol. Chem., 292, 2017
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6FIT
 | | FHIT-TRANSITION STATE ANALOG | | Descriptor: | ADENOSINE MONOTUNGSTATE, FRAGILE HISTIDINE TRIAD PROTEIN | | Authors: | Lima, C.D, Klein, M.G, Hendrickson, W.A. | | Deposit date: | 1997-09-25 | | Release date: | 1998-03-25 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure-based analysis of catalysis and substrate definition in the HIT protein family.
Science, 278, 1997
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4FUW
 | | Crystal structure of Ego3 mutant | | Descriptor: | Protein SLM4, SULFATE ION | | Authors: | Zhang, T, Peli-Gulli, M.P, Yang, H, De Virgilio, C, Ding, J. | | Deposit date: | 2012-06-28 | | Release date: | 2012-11-28 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Ego3 functions as a homodimer to mediate the interaction between Gtr1-Gtr2 and Ego1 in the ego complex to activate TORC1.
Structure, 20, 2012
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3A8R
 | | The structure of the N-terminal regulatory domain of a plant NADPH oxidase | | Descriptor: | CALCIUM ION, Putative uncharacterized protein | | Authors: | Oda, T, Hashimoto, H, Kuwabara, N, Akashi, S, Hayashi, K, Kojima, C, Wong, H.L, Kawasaki, T, Shimamoto, K, Sato, M, Shimizu, T. | | Deposit date: | 2009-10-07 | | Release date: | 2009-10-27 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The structure of the N-terminal regulatory domain of a plant NADPH oxidase and its functional implications
J.Biol.Chem., 285, 2010
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1ZJG
 | | 13mer-co | | Descriptor: | 5'-D(*AP*TP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*T)-3', 5'-D(*TP*AP*GP*CP*CP*CP*CP*GP*CP*CP*CP*CP*A)-3', COBALT HEXAMMINE(III), ... | | Authors: | Dohm, J.A, Hsu, M.H, Hwu, J.R, Huang, R.C, Moudrianakis, E.N, Lattman, E.E, Gittis, A.G. | | Deposit date: | 2005-04-28 | | Release date: | 2005-05-10 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Influence of Ions, Hydration, and the Transcriptional Inhibitor P4N on the Conformations of the Sp1 Binding Site.
J.Mol.Biol., 349, 2005
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5CWH
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2WQQ
 | | Crystallographic analysis of monomeric CstII | | Descriptor: | ALPHA-2,3-/2,8-SIALYLTRANSFERASE, CYTIDINE-5'-MONOPHOSPHATE-3-FLUORO-N-ACETYL-NEURAMINIC ACID, DI(HYDROXYETHYL)ETHER | | Authors: | Chan, P.H.W, Lairson, L.L, Lee, H.J, Wakarchuk, W.W, Strynadka, N.C.J, Withers, S.G, McIntosh, L.P. | | Deposit date: | 2009-08-25 | | Release date: | 2009-10-27 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | NMR Spectroscopic Characterization of the Sialyltransferase Cstii from Camplyobacter Jejuni: Histidine 188 is the General Base.
Biochemistry, 48, 2009
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1M0O
 | | Structure of Dialkylglycine Decarboxylase Complexed with 1-Amino-1-methylpropanephosphonate | | Descriptor: | (1R)-1-[((1E)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYLENE)AMINO]-1-METHYLPROPYLPHOSPHONIC ACID, 2,2-Dialkylglycine decarboxylase, POTASSIUM ION, ... | | Authors: | Liu, W, Rogers, C.J, Fisher, A.J, Toney, M.D. | | Deposit date: | 2002-06-13 | | Release date: | 2002-10-23 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Aminophosphonate Inhibitors of Dialkylglycine Decarboxylase: Structural Basis for Slow Binding Inhibition
Biochemistry, 41, 2002
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2WS1
 | | Semi-synthetic analogue of human insulin NMeTyrB26-insulin in monomer form | | Descriptor: | ACETATE ION, INSULIN A CHAIN, INSULIN B CHAIN | | Authors: | Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. | | Deposit date: | 2009-09-03 | | Release date: | 2010-02-09 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues.
Proc.Natl.Acad.Sci.USA, 107, 2010
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1RH1
 | | crystal structure of the cytotoxic bacterial protein colicin B at 2.5 A resolution | | Descriptor: | Colicin B | | Authors: | Hilsenbeck, J.L, Park, H, Chen, G, Youn, B, Postle, K, Kang, C. | | Deposit date: | 2003-11-13 | | Release date: | 2004-03-09 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of the cytotoxic bacterial protein colicin B at 2.5 A resolution
Mol.Microbiol., 51, 2004
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2WQH
 | | Crystal structure of CTPR3Y3 | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, ... | | Authors: | Krachler, A.M, Sharma, A, Kleanthous, C. | | Deposit date: | 2009-08-21 | | Release date: | 2010-04-07 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Self-association of TPR domains: Lessons learned from a designed, consensus-based TPR oligomer.
Proteins, 78, 2010
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2GQ6
 | | Crystal structure of an RNA racemate | | Descriptor: | CALCIUM ION, GLYCEROL, RNA (5'-R(*(0C)P*(0C)P*(0G)P*(0C)P*(0C)P*(0U)P*(0G)P*(0G))-3'), ... | | Authors: | Rypniewski, W, Vallazza, M, Perbandt, M, Klussmann, S, Betzel, C, Erdmann, V.A. | | Deposit date: | 2006-04-20 | | Release date: | 2006-06-27 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | The first crystal structure of an RNA racemate.
Acta Crystallogr.,Sect.D, 62, 2006
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2GQ4
 | | Crystal structure of an RNA racemate | | Descriptor: | CALCIUM ION, GLYCEROL, RNA (5'-R(*(0C)P*(0C)P*(0G)P*(0C)P*(0C)P*(0U)P*(0G)P*(0G))-3'), ... | | Authors: | Rypniewski, W, Vallazza, M, Perbandt, M, Klussmann, S, Betzel, C, Erdmann, V.A. | | Deposit date: | 2006-04-20 | | Release date: | 2006-06-27 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | The first crystal structure of an RNA racemate.
Acta Crystallogr.,Sect.D, 62, 2006
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3NF5
 | | Crystal structure of the C-terminal domain of nuclear pore complex component NUP116 from Candida glabrata | | Descriptor: | GLYCEROL, Nucleoporin NUP116 | | Authors: | Sampathkumar, P, Manglicmot, D, Bain, K, Gilmore, J, Gheyi, T, Rout, M, Sali, A, Atwell, S, Thompson, D.A, Emtage, J.S, Wasserman, S, Sauder, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2010-06-09 | | Release date: | 2010-08-04 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Atomic structure of the nuclear pore complex targeting domain of a Nup116 homologue from the yeast, Candida glabrata.
Proteins, 80, 2012
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2WS4
 | | Semi-synthetic analogue of human insulin ProB26-DTI in monomer form | | Descriptor: | INSULIN A CHAIN, INSULIN B CHAIN | | Authors: | Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. | | Deposit date: | 2009-09-03 | | Release date: | 2010-02-09 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues.
Proc.Natl.Acad.Sci.USA, 107, 2010
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1XUE
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5CHX
 | | Crystal Structure of amino acids 1590-1657 of MYH7 | | Descriptor: | Xrcc4-MYH7-1590-1657 | | Authors: | Korkmaz, N.E, Taylor, K.C, Andreas, M.P, Ajay, G, Heinz, N.T, Cui, Q, Rayment, I. | | Deposit date: | 2015-07-10 | | Release date: | 2015-12-02 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A composite approach towards a complete model of the myosin rod.
Proteins, 84, 2016
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2F69
 | | Ternary complex of SET7/9 bound to AdoHcy and a TAF10 peptide | | Descriptor: | Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Couture, J.-F, Collazo, E, Hauk, G, Trievel, R.C. | | Deposit date: | 2005-11-28 | | Release date: | 2006-01-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Structural basis for the methylation site specificity of SET7/9
Nat.Struct.Mol.Biol., 13, 2006
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1MA8
 | | A-DNA decamer GCGTA(UMS)ACGC with incorporated 2'-methylseleno-uridine | | Descriptor: | 5'-D(*GP*CP*GP*TP*AP*UMSP*AP*CP*GP*C)-3' | | Authors: | Teplova, M, Wilds, C.J, Wawrzak, Z, Tereshko, V, Du, Q, Carrasco, N, Huang, Z, Egli, M. | | Deposit date: | 2002-08-01 | | Release date: | 2002-12-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Covalent incorporation of selenium into oligonucleotides for X-ray crystal structure determination via MAD: proof of principle
BIOCHIMIE, 84, 2002
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3N9P
 | | ceKDM7A from C.elegans, complex with H3K4me3K27me2 peptide and NOG | | Descriptor: | FE (II) ION, Histone H3 peptide, N-OXALYLGLYCINE, ... | | Authors: | Yang, Y, Hu, L, Wang, P, Hou, H, Chen, C.D, Xu, Y. | | Deposit date: | 2010-05-31 | | Release date: | 2010-06-30 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.388 Å) | | Cite: | Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans
Cell Res., 20, 2010
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1MBL
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4EO7
 | | Crystal structure of the TIR domain of human myeloid differentiation primary response protein 88. | | Descriptor: | MAGNESIUM ION, Myeloid differentiation primary response protein MyD88 | | Authors: | Snyder, G.A, Cirl, C, Jiang, J.S, Chen, P, Smith, T, Xiao, T.S. | | Deposit date: | 2012-04-13 | | Release date: | 2013-04-10 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.449 Å) | | Cite: | Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli.
Proc.Natl.Acad.Sci.USA, 110, 2013
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2HEM
 | | NMR structure and Mg2+ binding of an RNA segment that underlies the L7/L12 stalk in the E.coli 50S ribosomal subunit. | | Descriptor: | 5'-R(P*GP*GP*GP*AP*AP*GP*GP*CP*GP*CP*UP*UP*CP*GP*GP*CP*GP*UP*CP*GP*GP*CP*CP*C)-3' | | Authors: | Zhao, Q, Nagaswamy, U, Lee, H, Xia, Y, Gao, X, Fox, G. | | Deposit date: | 2006-06-21 | | Release date: | 2006-09-12 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | NMR structure and Mg2+ binding of an RNA segment that underlies the L7/L12 stalk in the E.coli 50S ribosomal subunit
Nucleic Acids Res., 33, 2005
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