PDB: 1585 resultsInfo pagesStatus searchChemie searchBIRD

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8CDL	80S S. cerevisiae ribosome with ligands in hybrid-2 pre-translocation (PRE-H2) complex Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. Deposit date: 2023-01-31 Release date: 2023-09-20 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.72 Å) Cite: mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
8CIV	Translocation intermediate 5 (TI-5) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. Deposit date: 2023-02-10 Release date: 2023-09-20 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.47 Å) Cite: mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
8CMJ	Translocation intermediate 4 (TI-4*) of 80S S. cerevisiae ribosome with eEF2 in the absence of sordarin Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. Deposit date: 2023-02-20 Release date: 2023-09-20 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3.79 Å) Cite: mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
8CCS	80S S. cerevisiae ribosome with ligands in hybrid-1 pre-translocation (PRE-H1) complex Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. Deposit date: 2023-01-27 Release date: 2023-09-20 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (1.97 Å) Cite: mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
8CG8	Translocation intermediate 3 (TI-3) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. Deposit date: 2023-02-03 Release date: 2023-09-20 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.57 Å) Cite: mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
8CEH	Translocation intermediate 4 (TI-4) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. Deposit date: 2023-02-01 Release date: 2023-09-20 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.05 Å) Cite: mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
7K6P	Active state Dot1 bound to the unacetylated H4 nucleosome Descriptor: DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ... Authors: Valencia-Sanchez, M.I, De Ioannes, P.E, Miao, W, Truong, D.M, Lee, R, Armache, J.-P, Boeke, J.D, Armache, K.-J. Deposit date: 2020-09-21 Release date: 2021-02-10 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Regulation of the Dot1 histone H3K79 methyltransferase by histone H4K16 acetylation. Science, 371, 2021
7K5I	SARS-COV-2 nsp1 in complex with human 40S ribosome Descriptor: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... Authors: Wang, L, Shi, M, Wu, H. Deposit date: 2020-09-16 Release date: 2020-10-14 Last modified: 2024-10-09 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: SARS-CoV-2 Nsp1 suppresses host but not viral translation through a bipartite mechanism. Biorxiv, 2020
7K5J	Structure of an E1-E2-ubiquitin thioester mimetic Descriptor: ADENOSINE MONOPHOSPHATE, Ubiquitin, Ubiquitin-activating enzyme E1 1, ... Authors: Yuan, L, Lv, Z, Olsen, S.K. Deposit date: 2020-09-16 Release date: 2021-04-28 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.42 Å) Cite: Crystal structures of an E1-E2-ubiquitin thioester mimetic reveal molecular mechanisms of transthioesterification. Nat Commun, 12, 2021
7JQB	SARS-CoV-2 Nsp1 and rabbit 40S ribosome complex Descriptor: 40S ribosomal protein S21, 40S ribosomal protein S24, 40S ribosomal protein S26, ... Authors: Yuan, S, Xiong, Y. Deposit date: 2020-08-10 Release date: 2020-12-02 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA. Mol.Cell, 80, 2020
7K6Q	Active state Dot1 bound to the H4K16ac nucleosome Descriptor: DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ... Authors: Valencia-Sanchez, M.I, De Ioannes, P.E, Miao, W, Truong, D.M, Lee, R, Armache, J.-P, Boeke, J.D, Armache, K.-J. Deposit date: 2020-09-21 Release date: 2021-02-10 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Regulation of the Dot1 histone H3K79 methyltransferase by histone H4K16 acetylation. Science, 371, 2021
7JQC	SARS-CoV-2 Nsp1, CrPV IRES and rabbit 40S ribosome complex Descriptor: 40S ribosomal protein S21, 40S ribosomal protein S24, 40S ribosomal protein S26, ... Authors: Yuan, S, Xiong, Y. Deposit date: 2020-08-10 Release date: 2020-12-02 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA. Mol.Cell, 80, 2020
4P5O	Structure of an RBX1-UBC12~NEDD8-CUL1-DCN1 complex: a RING-E3-E2~ubiquitin-like protein-substrate intermediate trapped in action Descriptor: Cullin-1, DCN1-like protein 1, E3 ubiquitin-protein ligase RBX1, ... Authors: Scott, D.C, Schulman, B.A. Deposit date: 2014-03-18 Release date: 2014-07-02 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (3.1071 Å) Cite: Structure of a RING E3 Trapped in Action Reveals Ligation Mechanism for the Ubiquitin-like Protein NEDD8. Cell, 157, 2014
9F1B	Mammalian ternary complex of a translating 80S ribosome, NAC and NatA/E Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... Authors: Yudin, D, Scaiola, A, Ban, N. Deposit date: 2024-04-18 Release date: 2024-08-21 Last modified: 2024-10-02 Method: ELECTRON MICROSCOPY (3.01 Å) Cite: NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 633, 2024
9F1C	Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... Authors: Yudin, D, Scaiola, A, Ban, N. Deposit date: 2024-04-18 Release date: 2024-08-21 Last modified: 2024-10-02 Method: ELECTRON MICROSCOPY (3.78 Å) Cite: NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 633, 2024
9F1D	Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E-HYPK Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... Authors: Yudin, D, Scaiola, A, Ban, N. Deposit date: 2024-04-18 Release date: 2024-08-21 Last modified: 2024-10-02 Method: ELECTRON MICROSCOPY (3.26 Å) Cite: NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 633, 2024
9GMO	eIF6-bound pre-60S large ribosomal subunit incorporating mutant uL16 Descriptor: 28S rRNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5.8S rRNA, ... Authors: Bothe, A, Ban, N, Kostova, K. Deposit date: 2024-08-29 Release date: 2024-10-02 Method: ELECTRON MICROSCOPY (2.59 Å) Cite: ZNF574 is a Quality Control Factor For Defective Ribosome Biogenesis Intermediates. Biorxiv, 2024
4Q5H	Shigella Effector Kinase OspG bound to AMPPNP and E2-Ub UbcH7-Ub Conjugate Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Polyubiquitin, ... Authors: Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) Deposit date: 2014-04-16 Release date: 2014-07-02 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.999 Å) Cite: Structural Basis for the Inhibition of Host Protein Ubiquitination by Shigella Effector Kinase OspG. Structure, 22, 2014
9IPU	cryo-EM structure of the RNF168(1-193)/UbcH5c-Ub ubiquitylation module bound to H1.0-K63-Ub3 modified chromatosome Descriptor: DNA (171-MER), E3 ubiquitin-protein ligase RNF168, Histone H1.0, ... Authors: Ai, H.S, Deng, Z.H, Liu, L. Deposit date: 2024-07-11 Release date: 2024-10-02 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Chemically and Site-specifically Ubiquitylated Linker Histone H1 Facilitates RNF168-Mediated Nucleosomal H2A Ubiquitylation To Be Published
9G8O	human 40S ribosome bound by a SKI238-exosome complex Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... Authors: Koegel, A, Keidel, A, Loukeri, M.J, Kuhn, C.C, Langer, L.M, Schaefer, I.B, Conti, E. Deposit date: 2024-07-23 Release date: 2024-10-16 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis of mRNA decay by the human exosome-ribosome supercomplex. Nature, 2024
9G8M	human 80S ribosome bound by a SKI2-exosome complex Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Koegel, A, Keidel, A, Loukeri, M.J, Kuhn, C.C, Langer, L.M, Schaefer, I.B, Conti, E. Deposit date: 2024-07-23 Release date: 2024-10-23 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis of mRNA decay by the human exosome-ribosome supercomplex. Nature, 2024
4Q5E	Shigella Effector Kinase OspG bound to E2-Ub UbcH7-Ub Conjugate Descriptor: Polyubiquitin, Protein kinase OspG, Ubiquitin-conjugating enzyme E2 L3 Authors: Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) Deposit date: 2014-04-16 Release date: 2014-07-02 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.869 Å) Cite: Structural Basis for the Inhibition of Host Protein Ubiquitination by Shigella Effector Kinase OspG. Structure, 22, 2014
7UD5	Complex between MLL1-WRAD and an H2B-ubiquitinated nucleosome Descriptor: 601 DNA (146-MER), Histone H2A, Histone H2B 1.1, ... Authors: Niklas, H.A, Rahman, S, Worden, E.J, Wolberger, C. Deposit date: 2022-03-18 Release date: 2022-09-21 Last modified: 2022-10-05 Method: ELECTRON MICROSCOPY (4.25 Å) Cite: Multistate structures of the MLL1-WRAD complex bound to H2B-ubiquitinated nucleosome. Proc.Natl.Acad.Sci.USA, 119, 2022
7UN3	Complex of UBE2O with NAP1L1 and ubiquitylated uL2 Descriptor: Nucleosome assembly protein 1-like 1, Ubiquitin,60S ribosomal protein L8,(E3-independent) E2 ubiquitin-conjugating enzyme fusion Authors: Yip, M.C.J, Sedor, S.F, Shao, S. Deposit date: 2022-04-08 Release date: 2022-08-03 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Mechanism of client selection by the protein quality-control factor UBE2O. Nat.Struct.Mol.Biol., 29, 2022
7UPN	Maedi visna virus Vif in complex with CypA and E3 ubiquitin ligase Descriptor: Elongin-B, Elongin-C, Peptidyl-prolyl cis-trans isomerase A, ... Authors: Hu, Y, Xiong, Y. Deposit date: 2022-04-16 Release date: 2023-01-25 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural basis for recruitment of host CypA and E3 ubiquitin ligase by maedi-visna virus Vif. Sci Adv, 9, 2023

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