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1MA0
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BU of 1ma0 by Molmil
Ternary complex of Human glutathione-dependent formaldehyde dehydrogenase with NAD+ and dodecanoic acid
Descriptor: Glutathione-dependent formaldehyde dehydrogenase, LAURIC ACID, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Sanghani, P.C, Robinson, H, Bosron, W.F, Hurley, T.D.
Deposit date:2002-07-30
Release date:2002-08-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Human glutathione-dependent formaldehyde dehydrogenase. Structures of apo, binary, and inhibitory ternary complexes.
Biochemistry, 41, 2002
2JP7
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BU of 2jp7 by Molmil
NMR structure of the Mex67 UBA domain
Descriptor: mRNA export factor MEX67
Authors:Hobeika, M, Brockmann, C, Iglesias, N, Gwizdek, C, Neuhaus, D, Stutz, F, Stewart, M, Divita, G, Dargemont, C.
Deposit date:2007-04-26
Release date:2007-07-10
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:Coordination of Hpr1 and ubiquitin binding by the UBA domain of the mRNA export factor Mex67
Mol.Cell.Biol., 18, 2007
1DY3
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BU of 1dy3 by Molmil
Ternary complex of 7,8-dihydro-6-hydroxymethylpterinpyrophosphokinase from Escherichia coli with ATP and a substrate analogue.
Descriptor: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 7,8-DIHYDRO-6-HYDROXYMETHYL-7-METHYL-7-[2-PHENYLETHYL]-PTERIN, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Stammers, D.K, Achari, A, Somers, D.O, Bryant, P.K, Rosemond, J, Scott, D.L, Champness, J.N.
Deposit date:2000-01-21
Release date:2000-08-18
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:2.0A X-Ray Structure of the Ternary Complex of 7,8-Dihydro-6-Hydroxymethylpterinpyrophosphokinase from Escherichia Coli with ATP and a Substrate Analogue
FEBS Lett., 456, 1999
1C6X
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BU of 1c6x by Molmil
ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP.
Descriptor: N-[2(S)-CYCLOPENTYL-1(R)-HYDROXY-3(R)METHYL]-5-[(2(S)-TERTIARY-BUTYLAMINO-CARBONYL)-4-(N1-(2)-(N-METHYLPIPERAZINYL)-3-CHLORO-PYRAZINYL-5-CARBONYL)-PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYL-PENTANAMIDE, PROTEIN (PROTEASE)
Authors:Munshi, S.
Deposit date:1999-12-28
Release date:2000-12-28
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An alternate binding site for the P1-P3 group of a class of potent HIV-1 protease inhibitors as a result of concerted structural change in the 80s loop of the protease.
Acta Crystallogr.,Sect.D, 56, 2000
1C6Z
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BU of 1c6z by Molmil
ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP.
Descriptor: (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, PROTEIN (PROTEASE)
Authors:Munshi, S.
Deposit date:1999-12-28
Release date:2000-12-28
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An alternate binding site for the P1-P3 group of a class of potent HIV-1 protease inhibitors as a result of concerted structural change in the 80s loop of the protease.
Acta Crystallogr.,Sect.D, 56, 2000
1C6Y
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BU of 1c6y by Molmil
ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP.
Descriptor: N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE, PROTEIN (PROTEASE)
Authors:Munshi, S.
Deposit date:1999-12-28
Release date:2000-12-28
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An alternate binding site for the P1-P3 group of a class of potent HIV-1 protease inhibitors as a result of concerted structural change in the 80s loop of the protease.
Acta Crystallogr.,Sect.D, 56, 2000
1C70
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BU of 1c70 by Molmil
ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP.
Descriptor: N-[2(R)-HYDROXY-1(S)-INDANYL]-2(R)-PHENYLMETHYL-4(S)-HYDROXY-5-[4-[2-BENZOFURANYLMETHYL]-2(S)-[TERT-BUTYLAMINOCARBONYL]-PIPERAZINYL]-PENTANEAMIDE, PROTEIN (PROTEASE)
Authors:Munshi, S.
Deposit date:1999-12-29
Release date:2000-12-28
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An alternate binding site for the P1-P3 group of a class of potent HIV-1 protease inhibitors as a result of concerted structural change in the 80s loop of the protease.
Acta Crystallogr.,Sect.D, 56, 2000
1D15
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BU of 1d15 by Molmil
TERNARY INTERACTIONS OF SPERMINE WITH DNA: 4'-EPIADRIAMYCIN AND OTHER DNA: ANTHRACYCLINE COMPLEXES
Descriptor: 4'-EPIDOXORUBICIN, DNA (5'-D(*CP*GP*AP*TP*CP*G)-3'), SPERMINE
Authors:Williams, L.D, Frederick, C.A, Ughetto, G, Rich, A.
Deposit date:1990-07-03
Release date:1991-07-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Ternary interactions of spermine with DNA: 4'-epiadriamycin and other DNA: anthracycline complexes.
Nucleic Acids Res., 18, 1990
1RRA
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BU of 1rra by Molmil
RIBONUCLEASE A FROM RATTUS NORVEGICUS (COMMON RAT)
Descriptor: PHOSPHATE ION, PROTEIN (RIBONUCLEASE)
Authors:Gupta, V, Muyldermans, S, Wyns, L, Salunke, D.
Deposit date:1998-12-04
Release date:1998-12-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of recombinant rat pancreatic RNase A.
Proteins, 35, 1999
1RNC
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BU of 1rnc by Molmil
NEWLY OBSERVED BINDING MODE IN PANCREATIC RIBONUCLEASE
Descriptor: GUANOSINE-5'-MONOPHOSPHATE, RIBONUCLEASE A, SULFATE ION
Authors:Aguilar, C.F, Thomas, P.J, Mills, A, Moss, D.S, Palmer, R.A.
Deposit date:1991-10-21
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Newly observed binding mode in pancreatic ribonuclease.
J.Mol.Biol., 224, 1992
4K7L
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BU of 4k7l by Molmil
Crystal structure of RNase S variant (K7C/Q11C)
Descriptor: Ribonuclease pancreatic, SULFATE ION
Authors:Genz, M, Straeter, N.
Deposit date:2013-04-17
Release date:2014-05-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Crystal structure of RNase S with a [Hg(Cys2)] metal center in the S-peptide as a template for structure-based design of artificial metalloenzymes using peptide-protein complementation
To be Published
6MCI
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BU of 6mci by Molmil
Solution structure of 7SK stem-loop 1
Descriptor: 7SK RNA
Authors:Pham, V.V, D'Souza, V.M.
Deposit date:2018-08-31
Release date:2018-10-31
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:HIV-1 Tat interactions with cellular 7SK and viral TAR RNAs identifies dual structural mimicry.
Nat Commun, 9, 2018
1EWA
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BU of 1ewa by Molmil
Dehaloperoxidase and 4-iodophenol
Descriptor: 4-IODOPHENOL, DEHALOPEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:LaCount, M.W, Zhang, E, Chen, Y.P, Han, K, Whitton, M.M, Lincoln, D.E, Woodin, S.A, Lebioda, L.
Deposit date:2000-04-24
Release date:2000-05-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure and amino acid sequence of dehaloperoxidase from Amphitrite ornata indicate common ancestry with globins
J.Biol.Chem., 275, 2000
7QWH
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BU of 7qwh by Molmil
X-ray structure of the adduct formed upon reaction of a vanadium hydroxyquinoline complex with RNase A
Descriptor: 2,2-bis($l^{1}-oxidanyl)-3-oxa-1$l^{4}-aza-2$l^{4}-vanadatricyclo[6.3.1.0^{4,12}]dodeca-1(12),4,6,8,10-pentaene, Ribonuclease pancreatic
Authors:Merlino, A, Ferraro, G.
Deposit date:2022-01-25
Release date:2023-02-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.573 Å)
Cite:Interaction of VIVO-8-hydroxyquinoline species with RNase A: the effect of metal ligands in the protein adduct stabilization
Inorg Chem Front, 2023
5LLZ
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BU of 5llz by Molmil
Dehaloperoxidase B from Amphitrite ornata: benzotriazole complex
Descriptor: 1H-benzotriazole, Dehaloperoxidase B, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Chicano, T.M, Dworkowski, F.S.N, Hough, M.A.
Deposit date:2016-07-28
Release date:2017-08-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:Dehaloperoxidase B from Amphitrite ornata: benzotriazole complex
to be published
4POU
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BU of 4pou by Molmil
VHH-metal in Complex with RNase A
Descriptor: Ribonuclease pancreatic, VHH Antibody
Authors:Fanning, S.W, Walter, R, Horn, J.R.
Deposit date:2014-02-26
Release date:2014-09-24
Last modified:2014-10-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis of an engineered dual-specific antibody: conformational diversity leads to a hypervariable loop metal-binding site.
Protein Eng.Des.Sel., 27, 2014
2P47
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BU of 2p47 by Molmil
Complex of a camelid single-domain vhh antibody fragment with RNASE A at 2.5A resolution: SE5B-TRI crystal form with five se-met sites (L4M, M34, M51, F68M, M83) in vhh scaffold.
Descriptor: ANTIBODY CAB-RN05, Ribonuclease pancreatic
Authors:Tereshko, V, Uysal, S, Koide, A, Margalef, K, Koide, S, Kossiakoff, A.A.
Deposit date:2007-03-11
Release date:2008-03-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold
Protein Sci., 17, 2008
2OQF
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BU of 2oqf by Molmil
Structure of a synthetic, non-natural analogue of RNase A: [N71K(Ade), D83A]RNase A
Descriptor: Ribonuclease pancreatic
Authors:Boerema, D.J, Tereshko, V.A, Zhang, J.L, He, C, Kent, S.B.H.
Deposit date:2007-01-31
Release date:2008-02-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design, Synthesis, and Characterization of Non-natural RNase A Analogues with Enhanced Second-step Catalytic Activity
To be Published
2P48
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BU of 2p48 by Molmil
Complex of a camelid single-domain vhh antibody fragment with RNASE A at 2.3A resolution: SE5B-tetra crystal form with five se-met sites (L4M, M34, M51, F68M, M83) in vhh scaffold.
Descriptor: ANTIBODY CAB-RN05, Ribonuclease pancreatic, SULFATE ION
Authors:Tereshko, V, Uysal, S, Koide, A, Margalef, K, Koide, S, Kossiakoff, A.A.
Deposit date:2007-03-11
Release date:2008-03-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold
Protein Sci., 17, 2008
5NA9
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BU of 5na9 by Molmil
The X-ray structure of bovine pancreatic ribonuclease incubated in the presence of an excess of carboplatin (1:10 ratio)
Descriptor: CESIUM ION, CHLORIDE ION, Ribonuclease pancreatic, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2017-02-27
Release date:2017-08-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:A comparison study on RNase A oligomerization induced by cisplatin, carboplatin and oxaliplatin.
J. Inorg. Biochem., 173, 2017
8OQC
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BU of 8oqc by Molmil
Dirhodium tetraacetate/ribonuclease A adduct in the P3221 space group (1 h soaking)
Descriptor: CHLORIDE ION, FORMIC ACID, Ribonuclease pancreatic, ...
Authors:Loreto, D, Merlino, A, Maity, B, Ueno, T.
Deposit date:2023-04-12
Release date:2023-06-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Cross-Linked Crystals of Dirhodium Tetraacetate/RNase A Adduct Can Be Used as Heterogeneous Catalysts.
Inorg.Chem., 62, 2023
8OQG
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BU of 8oqg by Molmil
Cross-linked crystal of dirhodium tetraacetate/ribonuclease A adduct in the P3221 space group (high temperature data collection)
Descriptor: CHLORIDE ION, FORMIC ACID, Ribonuclease pancreatic, ...
Authors:Loreto, D, Merlino, A, Maity, B, Ueno, T.
Deposit date:2023-04-12
Release date:2023-06-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Cross-Linked Crystals of Dirhodium Tetraacetate/RNase A Adduct Can Be Used as Heterogeneous Catalysts.
Inorg.Chem., 62, 2023
3DI9
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BU of 3di9 by Molmil
Crystal structure of bovine pancreatic ribonuclease A variant (I81A)
Descriptor: CHLORIDE ION, Ribonuclease pancreatic, SULFATE ION
Authors:Kurpiewska, K, Font, J, Ribo, M, Vilanova, M, Lewinski, K.
Deposit date:2008-06-20
Release date:2008-07-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray crystallographic studies of RNase A variants engineered at the most destabilizing positions of the main hydrophobic core: further insight into protein stability
Proteins, 77, 2009
3DIB
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BU of 3dib by Molmil
Crystal structure of bovine pancreatic ribonuclease A variant (I106A)
Descriptor: CHLORIDE ION, Ribonuclease pancreatic, SULFATE ION
Authors:Kurpiewska, K, Font, J, Ribo, M, Vilanova, M, Lewinski, K.
Deposit date:2008-06-20
Release date:2008-07-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:X-ray crystallographic studies of RNase A variants engineered at the most destabilizing positions of the main hydrophobic core: further insight into protein stability
Proteins, 77, 2009
3DIC
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BU of 3dic by Molmil
Crystal structure of bovine pancreatic ribonuclease A variant (V108A)
Descriptor: CHLORIDE ION, Ribonuclease pancreatic, SULFATE ION
Authors:Kurpiewska, K, Font, J, Ribo, M, Vilanova, M, Lewinski, K.
Deposit date:2008-06-20
Release date:2008-07-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:X-ray crystallographic studies of RNase A variants engineered at the most destabilizing positions of the main hydrophobic core: further insight into protein stability
Proteins, 77, 2009

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数据于2024-08-14公开中

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