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7N8B
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BU of 7n8b by Molmil
Cycloheximide bound vacant 80S structure isolated from cbf5-D95A
Descriptor: 18S RIBOSOMAL RNA, 25S, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ...
Authors:Rai, J, Zhao, Y, Li, H.
Deposit date:2021-06-14
Release date:2022-05-11
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:CryoEM structures of pseudouridine-free ribosome suggest impacts of chemical modifications on ribosome conformations.
Structure, 30, 2022
6XA1
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BU of 6xa1 by Molmil
Structure of a drug-like compound stalled human translation termination complex
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.
Deposit date:2020-06-03
Release date:2020-10-07
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Selective inhibition of human translation termination by a drug-like compound.
Nat Commun, 11, 2020
6XIJ
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BU of 6xij by Molmil
Escherichia coli transcription-translation complex A (TTC-A) containing an 24 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Wang, C, Su, M, Ebright, R.H.
Deposit date:2020-06-20
Release date:2020-09-02
Last modified:2020-09-23
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Structural basis of transcription-translation coupling.
Science, 369, 2020
6XHX
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BU of 6xhx by Molmil
Crystal structure of the A2058-unmethylated Thermus thermophilus 70S ribosome in complex with erythromycin and protein Y (YfiA) at 2.55A resolution
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
Authors:Svetlov, M.S, Syroegin, E.A, Aleksandrova, E.V, Atkinson, G.C, Gregory, S.T, Mankin, A.S, Polikanov, Y.S.
Deposit date:2020-06-19
Release date:2020-12-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance.
Nat.Chem.Biol., 17, 2021
6XGF
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BU of 6xgf by Molmil
Escherichia coli transcription-translation complex B (TTC-B) containing an 30 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Wang, C, Su, M, Ebright, R.H.
Deposit date:2020-06-17
Release date:2020-09-02
Last modified:2020-09-23
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Structural basis of transcription-translation coupling.
Science, 369, 2020
8BHF
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BU of 8bhf by Molmil
Cryo-EM structure of stalled rabbit 80S ribosomes in complex with human CCR4-NOT and CNOT4
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S11, ...
Authors:Absmeier, E, Chandrasekaran, V, O'Reilly, F.J, Stowell, J.A.W, Rappsilber, J, Passmore, L.A.
Deposit date:2022-10-31
Release date:2023-09-06
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
Nat.Struct.Mol.Biol., 30, 2023
8BH4
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BU of 8bh4 by Molmil
Elongating E. coli 70S ribosome containing deacylated tRNA(iMet) in the P-site and AAm6A mRNA codon with cognate dipeptidyl-tRNA(Lys) in the A-site
Descriptor: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ...
Authors:Koziej, L, Glatt, S.
Deposit date:2022-10-29
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:Modulation of translational decoding by m 6 A modification of mRNA.
Nat Commun, 14, 2023
8BHL
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BU of 8bhl by Molmil
Elongating E. coli 70S ribosome containing acylated tRNA(iMet) in the P-site and Am6AA mRNA codon in the A-site after uncompleted di-peptide formation
Descriptor: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ...
Authors:Koziej, L, Glatt, S.
Deposit date:2022-10-31
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (2.21 Å)
Cite:Modulation of translational decoding by m 6 A modification of mRNA.
Nat Commun, 14, 2023
8BGE
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BU of 8bge by Molmil
Elongating E. coli 70S ribosome containing acylated tRNA(iMet) in the P-site and AAm6A mRNA codon in the A-site after uncompleted di-peptide formation
Descriptor: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ...
Authors:Koziej, L, Glatt, S.
Deposit date:2022-10-27
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (2.11 Å)
Cite:Modulation of translational decoding by m 6 A modification of mRNA.
Nat Commun, 14, 2023
8BHP
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BU of 8bhp by Molmil
Elongating E. coli 70S ribosome containing acylated tRNA(iMet) in the P-site and m6AAA mRNA codon in the A-site after uncompleted di-peptide formation
Descriptor: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ...
Authors:Koziej, L, Glatt, S.
Deposit date:2022-10-31
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (2.37 Å)
Cite:Modulation of translational decoding by m 6 A modification of mRNA.
Nat Commun, 14, 2023
8BHJ
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BU of 8bhj by Molmil
Elongating E. coli 70S ribosome containing deacylated tRNA(iMet) in the P-site and Am6AA mRNA codon with cognate dipeptidyl-tRNA(Lys) in the A-site
Descriptor: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ...
Authors:Koziej, L, Glatt, S.
Deposit date:2022-10-31
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:Modulation of translational decoding by m 6 A modification of mRNA.
Nat Commun, 14, 2023
8BHN
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BU of 8bhn by Molmil
Elongating E. coli 70S ribosome containing deacylated tRNA(iMet) in the P-site and m6AAA mRNA codon with cognate dipeptidyl-tRNA(Lys) in the A-site
Descriptor: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ...
Authors:Koziej, L, Glatt, S.
Deposit date:2022-10-31
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Modulation of translational decoding by m 6 A modification of mRNA.
Nat Commun, 14, 2023
6Y2L
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BU of 6y2l by Molmil
Structure of human ribosome in POST state
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ...
Authors:Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A.
Deposit date:2020-02-16
Release date:2020-04-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes.
Cell Rep, 31, 2020
8BIM
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BU of 8bim by Molmil
Initiation complex of the E. coli 70S ribosome with mRNA containing AAm6A codon in the A-site
Descriptor: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ...
Authors:Koziej, L, Glatt, S.
Deposit date:2022-11-02
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (2.04 Å)
Cite:Modulation of translational decoding by m 6 A modification of mRNA.
Nat Commun, 14, 2023
8BGH
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BU of 8bgh by Molmil
Elongating E. coli 70S ribosome containing acylated tRNA(iMet) in the P-site and AAA mRNA codon in the A-site after uncompleted di-peptide formation
Descriptor: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ...
Authors:Koziej, L, Glatt, S.
Deposit date:2022-10-27
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Modulation of translational decoding by m 6 A modification of mRNA.
Nat Commun, 14, 2023
8BF7
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BU of 8bf7 by Molmil
Elongating E. coli 70S ribosome containing deacylated tRNA(iMet) in the P-site and AAA mRNA codon with cognate dipeptidyl-tRNA(Lys) in the A-site
Descriptor: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ...
Authors:Koziej, L, Glatt, S.
Deposit date:2022-10-24
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (2.33 Å)
Cite:Modulation of translational decoding by m 6 A modification of mRNA.
Nat Commun, 14, 2023
8BH6
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BU of 8bh6 by Molmil
Mature 30S ribosomal subunit from Staphylococcus aureus
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Garaeva, N, Fatkhullin, B, Jenner, L, Soufari, H, Yusupov, M, Usachev, K.
Deposit date:2022-10-30
Release date:2023-09-20
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Ribosome maturation factor P (RimP) from Staphylococcus aureus
Structure, 2023
8BIL
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BU of 8bil by Molmil
Initiation complex of the E. coli 70S ribosome with mRNA containing AAA codon in the A-site.
Descriptor: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ...
Authors:Koziej, L, Glatt, S.
Deposit date:2022-11-02
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (2.04 Å)
Cite:Modulation of translational decoding by m 6 A modification of mRNA.
Nat Commun, 14, 2023
8BH7
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BU of 8bh7 by Molmil
The complex of immature 30S ribosomal subunit with Ribosome maturation factor P (RimP) from Staphylococcus aureus
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Garaeva, N, Fatkhullin, B, Jenner, L, Soufari, H, Yusupov, M, Usachev, K.
Deposit date:2022-10-30
Release date:2023-09-20
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (4.23 Å)
Cite:Ribosome maturation factor P (RimP) from Staphylococcus aureus
Structure, 2023
7NRD
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BU of 7nrd by Molmil
Structure of the yeast Gcn1 bound to a colliding stalled 80S ribosome with MBF1, A/P-tRNA and P/E-tRNA
Descriptor: 25S rRNA (3184-MER), 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Pochopien, A.A, Beckert, B, Wilson, D.N.
Deposit date:2021-03-03
Release date:2021-04-14
Method:ELECTRON MICROSCOPY (4.36 Å)
Cite:Structure of Gcn1 bound to stalled and colliding 80S ribosomes.
Proc.Natl.Acad.Sci.USA, 118, 2021
7NRC
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BU of 7nrc by Molmil
Structure of the yeast Gcn1 bound to a leading stalled 80S ribosome with Rbg2, Gir2, A- and P-tRNA and eIF5A
Descriptor: 18S rRNA (1771-MER), 25S rRNA (3184-MER), 40S ribosomal protein S0-A, ...
Authors:Pochopien, A.A, Beckert, B, Wilson, D.N.
Deposit date:2021-03-03
Release date:2021-05-05
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of Gcn1 bound to stalled and colliding 80S ribosomes.
Proc.Natl.Acad.Sci.USA, 118, 2021
7O81
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BU of 7o81 by Molmil
Rabbit 80S ribosome colliding in another ribosome stalled by the SARS-CoV-2 pseudoknot
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ...
Authors:Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N.
Deposit date:2021-04-14
Release date:2021-06-02
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome.
Science, 372, 2021
7O7Y
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BU of 7o7y by Molmil
Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot (high resolution)
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ...
Authors:Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N.
Deposit date:2021-04-14
Release date:2021-06-02
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome.
Science, 372, 2021
7O80
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BU of 7o80 by Molmil
Rabbit 80S ribosome in complex with eRF1 and ABCE1 stalled at the STOP codon in the mutated SARS-CoV-2 slippery site
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ...
Authors:Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N.
Deposit date:2021-04-14
Release date:2021-06-02
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome.
Science, 372, 2021
6XHY
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BU of 6xhy by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with telithromycin, mRNA, aminoacylated A- and P-site tRNAs, and deacylated E-site tRNA at 2.60A resolution
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Svetlov, M.S, Syroegin, E.A, Aleksandrova, E.V, Atkinson, G.C, Gregory, S.T, Mankin, A.S, Polikanov, Y.S.
Deposit date:2020-06-19
Release date:2020-12-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance.
Nat.Chem.Biol., 17, 2021

222415

数据于2024-07-10公开中

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