8PAE
 
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8PAG
 | | Crystal structure of the ectodomain of Norway rat pestivirus E2 glycoprotein | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Aitkenhead, H, Stuart, D.I, EL Omari, K. | | Deposit date: | 2023-06-07 | | Release date: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structural comparison of typical and atypical E2 pestivirus glycoproteins.
Structure, 32, 2024
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8PAB
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8OQI
 | | Cryo-EM structure of the wild-type alpha-synuclein fibril. | | Descriptor: | Alpha-synuclein | | Authors: | Pesch, V, Reithofer, S, Ma, L, Flores-Fernandez, J.M, Oezduezenciler, P, Busch, Y, Lien, Y, Rudtke, O, Frieg, B, Schroeder, G.F, Wille, H, Tamgueney, G. | | Deposit date: | 2023-04-12 | | Release date: | 2024-03-13 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Vaccination with structurally adapted fungal protein fibrils induces immunity to Parkinson's disease.
Brain, 147, 2024
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5EM0
 | | Crystal structure of mugwort allergen Art v 4 | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Pollen allergen Art v 4.01, SODIUM ION | | Authors: | Offermann, L.R, Perdue, M.L, Chruszcz, M. | | Deposit date: | 2015-11-05 | | Release date: | 2016-06-08 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Structural, Functional, and Immunological Characterization of Profilin Panallergens Amb a 8, Art v 4, and Bet v 2.
J.Biol.Chem., 291, 2016
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8OZ3
 | | Crystal structure of scFv ATOR 1017 bound to human 4-1BB | | Descriptor: | Single chain Fv, Tumor necrosis factor receptor superfamily member 9 | | Authors: | Hakansson, M, Von Schantz, L, Rose, N. | | Deposit date: | 2023-05-08 | | Release date: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | ATOR-1017 (evunzekibart), an Fc-gamma receptor conditional 4-1BB agonist designed for optimal safety and efficacy, activates exhausted T cells in combination with anti-PD-1.
Cancer Immunol.Immunother., 72, 2023
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7NC0
 | | The structure of the humanised A33 Fab C226S variant, an immunotherapy candidate for colorectal cancer | | Descriptor: | A33 Fab heavy chain, A33 Fab light chain | | Authors: | Tang, J, Zhang, C, Dalby, P, Kozielski, F. | | Deposit date: | 2021-01-28 | | Release date: | 2022-03-02 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The structure of the humanised A33 Fab C226S variant, an immunotherapy candidate for colorectal cancer
To Be Published
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6Y5W
 | | Crystal structure of the envelope glycoprotein complex of Andes virus in a near postfusion conformation | | Descriptor: | Envelope polyprotein,Envelope polyprotein, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Serris, A, Rey, F.A, Guardado-Calvo, P. | | Deposit date: | 2020-02-26 | | Release date: | 2020-10-14 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism.
Cell, 183, 2020
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7NFA
 | | The structure of the humanised A33 Fab C226S variant, an immunotherapy candidate for colorectal cancer | | Descriptor: | A33 Fab heavy chain, A33 Fab light chain | | Authors: | Tang, J, Zhang, C, Dalby, P, Kozielski, F. | | Deposit date: | 2021-02-05 | | Release date: | 2022-03-02 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The structure of the humanised A33 Fab C226S variant, an immunotherapy candidate for colorectal cancer
To Be Published
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5XXZ
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1IVZ
 | | Solution structure of the SEA domain from murine hypothetical protein homologous to human mucin 16 | | Descriptor: | hypothetical protein 1110008I14RIK | | Authors: | Maeda, T, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2002-04-02 | | Release date: | 2002-10-02 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the SEA domain from the murine homologue of ovarian cancer antigen CA125 (MUC16)
J.Biol.Chem., 279, 2004
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5EWO
 | | Crystal structure of the human astrovirus 1 capsid protein spike domain at 0.95-A resolution | | Descriptor: | SULFATE ION, Structural protein | | Authors: | Bogdanoff, W, York, R.L, Yousefi, P.A, Haile, S, Tripathi, S, DuBois, R.M. | | Deposit date: | 2015-11-20 | | Release date: | 2015-12-23 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (0.95 Å) | | Cite: | Structural, Mechanistic, and Antigenic Characterization of the Human Astrovirus Capsid.
J.Virol., 90, 2015
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6Y6P
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5EVE
 | | Crystal structure of Amb a 8 in complex with poly-Pro10 | | Descriptor: | Poly-Proline peptide, Profilin | | Authors: | Offermann, L.R, Schlachter, C.R, Garrett, J, Chruszcz, M. | | Deposit date: | 2015-11-19 | | Release date: | 2016-06-08 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structural, Functional, and Immunological Characterization of Profilin Panallergens Amb a 8, Art v 4, and Bet v 2.
J.Biol.Chem., 291, 2016
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3S3Y
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6F6O
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6Y62
 | | Crystal structure of the envelope glycoprotein complex of Maporal virus in a prefusion conformation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein,Envelope polyprotein, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Serris, A, Rey, F.A, Guardado-Calvo, P. | | Deposit date: | 2020-02-26 | | Release date: | 2020-10-14 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism.
Cell, 183, 2020
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7B17
 | | SARS-CoV-spike RBD bound to two neutralising nanobodies. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SARS-CoV-2 neutralizing biparatopic nanobody VE,nanobody E from Lama glama,SARS-CoV-2 neutralizing biparatopic nanobody VE,nanobody E from Lama glama, Spike protein S1 | | Authors: | Hallberg, B.M, Das, H. | | Deposit date: | 2020-11-23 | | Release date: | 2021-02-10 | | Last modified: | 2022-12-21 | | Method: | ELECTRON MICROSCOPY (4.01 Å) | | Cite: | Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape
Science, 371, 2021
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5EWN
 | | Crystal structure of the human astrovirus 1 capsid protein core domain at 2.6 A resolution | | Descriptor: | CHLORIDE ION, Structural protein | | Authors: | York, R.L, Yousefi, P.A, Bogdanoff, W, Haile, S, Tripathi, S, DuBois, R.M. | | Deposit date: | 2015-11-20 | | Release date: | 2015-12-23 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (2.602 Å) | | Cite: | Structural, Mechanistic, and Antigenic Characterization of the Human Astrovirus Capsid.
J.Virol., 90, 2015
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3S7I
 | | Crystal structure of Ara h 1 | | Descriptor: | Allergen Ara h 1, clone P41B, CHLORIDE ION | | Authors: | Chruszcz, M, Maleki, S.J, Solberg, R, Minor, W. | | Deposit date: | 2011-05-26 | | Release date: | 2011-09-21 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structural and Immunologic Characterization of Ara h 1, a Major Peanut Allergen.
J.Biol.Chem., 286, 2011
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3S3Z
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6Y68
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1K33
 | | Crystal structure analysis of the gp41 core mutant | | Descriptor: | Transmembrane glycoprotein GP41 | | Authors: | Shu, W, Lu, M. | | Deposit date: | 2001-10-01 | | Release date: | 2001-10-10 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Interhelical interactions in the gp41 core: implications for activation of HIV-1 membrane fusion.
Biochemistry, 41, 2002
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4Q6Y
 | | Crystal structure of a chemoenzymatic glycoengineered disialylated Fc (di-sFc) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Ahmed, A.A, Giddens, J, Pincetic, A, Lomino, J.V, Ravetch, J.V, Wang, L.X, Bjorkman, P.J. | | Deposit date: | 2014-04-23 | | Release date: | 2014-07-23 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural characterization of anti-inflammatory immunoglobulin g fc proteins.
J.Mol.Biol., 426, 2014
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6Y6Q
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