1S6W
 
 | | Solution Structure of hybrid white striped bass hepcidin | | Descriptor: | Hepcidin | | Authors: | Babon, J.J, Singh, S, Pennington, M.W, Norton, R.S, Westerman, M.E. | | Deposit date: | 2004-01-28 | | Release date: | 2004-12-14 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Bass hepcidin synthesis, solution structure, antimicrobial activities and synergism, and in vivo hepatic response to bacterial infections.
J.Biol.Chem., 280, 2005
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7JM6
 | | Structure of chicken CLC-7 | | Descriptor: | (2R)-3-{[(R)-hydroxy{[(1S,2R,3S,4S,5R,6R)-2,3,4,6-tetrahydroxy-5-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dinonanoate, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | | Authors: | Schrecker, M, Hite, R. | | Deposit date: | 2020-07-31 | | Release date: | 2020-09-02 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (2.92 Å) | | Cite: | Cryo-EM structure of the lysosomal chloride-proton exchanger CLC-7 in complex with OSTM1.
Elife, 9, 2020
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8DB3
 | | Crystal structure of KaiC with truncated C-terminal coiled-coil domain | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Circadian clock protein KaiC | | Authors: | Padua, R.A.P, Grant, T, Pitsawong, W, Hoemberger, M.S, Otten, R, Bradshaw, N, Grigorieff, N, Kern, D. | | Deposit date: | 2022-06-14 | | Release date: | 2023-03-22 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | From primordial clocks to circadian oscillators.
Nature, 616, 2023
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8DBA
 | | Crystal structure of dodecameric KaiC | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Circadian clock protein KaiC, MAGNESIUM ION | | Authors: | Padua, R.A.P, Grant, T, Pitsawong, W, Hoemberger, M.S, Otten, R, Bradshaw, N, Grigorieff, N, Kern, D. | | Deposit date: | 2022-06-14 | | Release date: | 2023-03-22 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | From primordial clocks to circadian oscillators.
Nature, 616, 2023
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8VK3
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8VK4
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4BY9
 | | The structure of the Box CD enzyme reveals regulation of rRNA methylation | | Descriptor: | 5'-R(*UP*CP*GP*CP*CP*CP*AP*UP*CP*AP*CP)-3', 50S RIBOSOMAL PROTEIN L7AE, FIBRILLARIN-LIKE RRNA/TRNA 2'-O-METHYLTRANSFERASE, ... | | Authors: | Lapinaite, A, Simon, B, Skjaerven, L, Rakwalska-Bange, M, Gabel, F, Carlomagno, T. | | Deposit date: | 2013-07-18 | | Release date: | 2013-10-09 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | The Structure of the Box C/D Enzyme Reveals Regulation of RNA Methylation.
Nature, 502, 2013
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6HPO
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2YVE
 | | Crystal structure of the methylene blue-bound form of the multi-drug binding transcriptional repressor CgmR | | Descriptor: | 3,7-BIS(DIMETHYLAMINO)PHENOTHIAZIN-5-IUM, CHLORIDE ION, GLYCEROL, ... | | Authors: | Itou, H, Shirakihara, Y, Tanaka, I. | | Deposit date: | 2007-04-12 | | Release date: | 2008-04-15 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Crystal Structures of the Multidrug Binding Repressor Corynebacteriumglutamicum CgmR in Complex with Inducers and with an Operator
J.Mol.Biol., 403, 2010
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3WN7
 | | Crystal Structure of Keap1 in Complex with the N-terminal region of the Nrf2 transcription factor | | Descriptor: | ACETATE ION, Kelch-like ECH-associated protein 1, Peptide from Nuclear factor erythroid 2-related factor 2 | | Authors: | Fukutomi, T, Takagi, K, Mizushima, T, Ohuchi, N, Yamamoto, M. | | Deposit date: | 2013-12-05 | | Release date: | 2013-12-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.57 Å) | | Cite: | Kinetic, thermodynamic, and structural characterizations of the association between Nrf2-DLGex degron and Keap1
Mol.Cell.Biol., 34, 2014
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8ADN
 | | Vairimorpha necatrix 20S proteasome from spores | | Descriptor: | Proteasome Inhibitor 31-Like, Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, ... | | Authors: | Jespersen, N, Ehrenbolger, K, Winiger, R, Svedberg, D, Vossbrinck, C.R, Barandun, J. | | Deposit date: | 2022-07-08 | | Release date: | 2022-11-23 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (2.77 Å) | | Cite: | Structure of the reduced microsporidian proteasome bound by PI31-like peptides in dormant spores.
Nat Commun, 13, 2022
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2ZOZ
 | | Crystal structure of the ethidium-bound form of the multi-drug binding transcriptional repressor CgmR | | Descriptor: | ETHIDIUM, GLYCEROL, SULFATE ION, ... | | Authors: | Itou, H, Shirakihara, Y, Tanaka, I. | | Deposit date: | 2008-06-20 | | Release date: | 2008-07-08 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Crystal Structures of the Multidrug Binding Repressor Corynebacteriumglutamicum CgmR in Complex with Inducers and with an Operator
J.Mol.Biol., 403, 2010
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8VZ0
 | | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-400 | | Descriptor: | (1S,2R,4S)-N-(cyclopropylmethyl)-5,6-bis(4-hydroxyphenyl)-N-(4-methoxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, Estrogen receptor | | Authors: | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | | Deposit date: | 2024-02-09 | | Release date: | 2024-06-12 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8VZ1
 | | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-409 | | Descriptor: | 4,4'-[(1S,4S,5R)-5-(6-methoxy-3,4-dihydroquinoline-1(2H)-sulfonyl)-7-oxabicyclo[2.2.1]hept-2-ene-2,3-diyl]diphenol, Estrogen receptor | | Authors: | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | | Deposit date: | 2024-02-09 | | Release date: | 2024-06-12 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8VZP
 | | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-403 | | Descriptor: | (1S,2R,4S)-N-(2-hydroxyethyl)-5,6-bis(4-hydroxyphenyl)-N-(4-methoxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, Estrogen receptor | | Authors: | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | | Deposit date: | 2024-02-12 | | Release date: | 2024-06-12 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8VYT
 | | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-411 | | Descriptor: | 4,4'-[(1R,4R,5S)-5-(2,3-dihydro-1H-indole-1-sulfonyl)-7-oxabicyclo[2.2.1]hept-2-ene-2,3-diyl]diphenol, Estrogen receptor | | Authors: | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | | Deposit date: | 2024-02-09 | | Release date: | 2024-06-12 | | Method: | X-RAY DIFFRACTION (1.61 Å) | | Cite: | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8VYX
 | | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-410 | | Descriptor: | 4,4'-[(1S,4S,5R)-5-(3,4-dihydroquinoline-1(2H)-sulfonyl)-7-oxabicyclo[2.2.1]hept-2-ene-2,3-diyl]diphenol, Estrogen receptor | | Authors: | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | | Deposit date: | 2024-02-09 | | Release date: | 2024-06-12 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8VZQ
 | | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-406 | | Descriptor: | (1S,2R,4S)-N-(2-fluoro-2-methylpropyl)-5,6-bis(4-hydroxyphenyl)-N-(4-methoxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, Estrogen receptor, NICKEL (II) ION | | Authors: | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | | Deposit date: | 2024-02-12 | | Release date: | 2024-06-12 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8W03
 | | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-1154 | | Descriptor: | (1S,2R,4S)-N-(4-chlorophenyl)-5,6-bis(4-hydroxyphenyl)-N-(2,2,2-trifluoroethyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, Estrogen receptor | | Authors: | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | | Deposit date: | 2024-02-13 | | Release date: | 2024-06-12 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8W07
 | | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-402 | | Descriptor: | (1R,2S,4R)-N-cyclohexyl-5,6-bis(4-hydroxyphenyl)-N-(4-methoxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, (1S,2R,4S)-N-cyclohexyl-5,6-bis(4-hydroxyphenyl)-N-(4-methoxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, Estrogen receptor | | Authors: | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.K, Nettles, K.W. | | Deposit date: | 2024-02-13 | | Release date: | 2024-06-12 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu.
Proc.Natl.Acad.Sci.USA, 121, 2024
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2LKP
 | | solution structure of apo-NmtR | | Descriptor: | HTH-type transcriptional regulator NmtR | | Authors: | Lee, C, Giedroc, D. | | Deposit date: | 2011-10-18 | | Release date: | 2012-04-18 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of Mycobacterium tuberculosis NmtR in the Apo State: Insights into Ni(II)-Mediated Allostery.
Biochemistry, 51, 2012
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7T5P
 | | Cryo-EM structure of human SIMC1-SLF2 complex | | Descriptor: | SMC5-SMC6 complex localization factor protein 2, SUMO-interacting motif-containing protein 1 | | Authors: | Maeda, S, Oravcova, M, Boddy, M.N, Otomo, T. | | Deposit date: | 2021-12-13 | | Release date: | 2022-12-07 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.
Elife, 11, 2022
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2KB7
 | | Hybrid solution and solid-state NMR structure of monomeric phospholamban in lipid bilayers | | Descriptor: | Phospholamban | | Authors: | Traaseth, N.J, Shi, L, Verardi, R, Veglia, G. | | Deposit date: | 2008-11-21 | | Release date: | 2009-06-16 | | Last modified: | 2024-05-22 | | Method: | SOLID-STATE NMR, SOLUTION NMR | | Cite: | Structure and topology of monomeric phospholamban in lipid membranes determined by a hybrid solution and solid-state NMR approach.
Proc.Natl.Acad.Sci.USA, 106, 2009
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2K1N
 | | DNA bound structure of the N-terminal domain of AbrB | | Descriptor: | AbrB family transcriptional regulator, DNA (25-MER) | | Authors: | Cavanagh, J, Bobay, B.G, Sullivan, D.M, Thompson, R.J. | | Deposit date: | 2008-03-10 | | Release date: | 2008-11-11 | | Last modified: | 2022-03-16 | | Method: | SOLUTION NMR | | Cite: | Insights into the Nature of DNA Binding of AbrB-like Transcription Factors
Structure, 16, 2008
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2YVH
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