9CMW
 
 | | The cryo-EM structure of BamACDE complex from Neisseria gonorrhoeae | | Descriptor: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamD, Outer membrane protein assembly factor BamE, ... | | Authors: | Billings, E.M, Noinaj, N. | | Deposit date: | 2024-07-15 | | Release date: | 2025-09-03 | | Last modified: | 2025-11-19 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structural insights into outer membrane protein biogenesis in pathogenic Neisseria.
Structure, 33, 2025
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7QCJ
 | | Structure of SARS-CoV-2 Papain-like Protease bound to N-(2,4-dihydroxybenzylidene)-thiosemicarbazone | | Descriptor: | CHLORIDE ION, GLYCEROL, N-(2,4-dihydroxybenzylidene)-thiosemicarbazone, ... | | Authors: | Ewert, W, Gunther, S, Reinke, P, Falke, S, Lieske, J, Miglioli, F, Carcelli, M, Srinivasan, V, Betzel, C, Han, H, Lorenzen, K, Guenther, C, Niebling, S, Garcia-Alai, M, Hinrichs, W, Rogolino, D, Meents, A. | | Deposit date: | 2021-11-24 | | Release date: | 2022-03-16 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Hydrazones and Thiosemicarbazones Targeting Protein-Protein-Interactions of SARS-CoV-2 Papain-like Protease.
Front Chem, 10, 2022
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7W6C
 | | Crystal structure of a PSH1 in complex with ligand J1K | | Descriptor: | 4-(2-hydroxyethylcarbamoyl)benzoic acid, PSH1 | | Authors: | Gao, J, Lara, P, Li, Z.S, Han, X, Wei, R, Liu, W.D. | | Deposit date: | 2021-12-01 | | Release date: | 2022-09-14 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Multiple Substrate Binding Mode-Guided Engineering of a Thermophilic PET Hydrolase.
Acs Catalysis, 12, 2022
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9CLF
 | | Importin alpha isoform 2 with synthetic zero net-charge nuclear localization signal | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, Importin subunit alpha-1, ... | | Authors: | Zeytuni, N, Yang, Z, Odeh-Ahmed, A, Abdoli, A, Leyton, V.J, Bednova, O, Lavigne, P, Lemieux, B. | | Deposit date: | 2024-07-11 | | Release date: | 2025-09-03 | | Method: | X-RAY DIFFRACTION (2.36 Å) | | Cite: | Probing the extent of importin-alpha targeting of the TAF8 NLS by eliminating its cationic net-charge.
Protein Sci., 34, 2025
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7QPY
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7QPG
 | | Human RZZ kinetochore corona complex. | | Descriptor: | Centromere/kinetochore protein zw10 homolog, Kinetochore-associated protein 1, Protein zwilch homolog | | Authors: | Raisch, T, Ciossani, G, d'Amico, E, Cmetowski, V, Carmignani, S, Maffini, S, Merino, F, Wohlgemuth, S, Vetter, I.R, Raunser, S, Musacchio, A. | | Deposit date: | 2022-01-04 | | Release date: | 2022-03-16 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structure of the RZZ complex and molecular basis of Spindly-driven corona assembly at human kinetochores.
Embo J., 41, 2022
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9CLE
 | | Importin alpha isoform 2 with synthetic zero net-charge nuclear localization signal | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, Importin subunit alpha-1, ... | | Authors: | Zeytuni, N, Yang, Z, Odeh-Ahmed, A, Abdoli, A, Leyton, V.J, Bednova, O, Lavigne, P, Lemieux, B. | | Deposit date: | 2024-07-11 | | Release date: | 2025-09-03 | | Method: | X-RAY DIFFRACTION (2.34 Å) | | Cite: | Probing the extent of importin-alpha targeting of the TAF8 NLS by eliminating its cationic net-charge.
Protein Sci., 34, 2025
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7WK0
 | | Local refine of Omicron spike bitrimer with 6m6 antibody | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6m6 heavy chain, 6m6 light chain, ... | | Authors: | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | | Deposit date: | 2022-01-08 | | Release date: | 2022-07-13 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.32 Å) | | Cite: | A broadly neutralizing antibody against SARS-CoV-2 Omicron variant infection exhibiting a novel trimer dimer conformation in spike protein binding.
Cell Res., 32, 2022
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7QO5
 | | 26S proteasome Rpt1-RK -Ubp6-UbVS complex in the si state | | Descriptor: | 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ... | | Authors: | Hung, K.Y.S, Klumpe, S, Eisele, M.R, Elsasser, S, Geng, T.T, Cheng, T.C, Joshi, T, Rudack, T, Sakata, E, Finley, D. | | Deposit date: | 2021-12-23 | | Release date: | 2022-03-16 | | Last modified: | 2023-03-15 | | Method: | ELECTRON MICROSCOPY (6 Å) | | Cite: | Allosteric control of Ubp6 and the proteasome via a bidirectional switch.
Nat Commun, 13, 2022
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7W69
 | | Crystal structure of a PSH1 mutant in complex with EDO | | Descriptor: | 1,2-ETHANEDIOL, PSH1 | | Authors: | Gao, J, Lara, P, Li, Z.S, Han, X, Wei, R, Liu, W.D. | | Deposit date: | 2021-12-01 | | Release date: | 2022-09-14 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.56 Å) | | Cite: | Multiple Substrate Binding Mode-Guided Engineering of a Thermophilic PET Hydrolase.
Acs Catalysis, 12, 2022
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7WJY
 | | Omicron spike trimer with 6m6 antibody | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6m6 heavy chain, 6m6 light chain, ... | | Authors: | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | | Deposit date: | 2022-01-08 | | Release date: | 2022-07-13 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.24 Å) | | Cite: | A broadly neutralizing antibody against SARS-CoV-2 Omicron variant infection exhibiting a novel trimer dimer conformation in spike protein binding.
Cell Res., 32, 2022
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7QBH
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9CL8
 | | Importin alpha isoform 2 with synthetic zero net-charge nuclear localization signal | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, Importin subunit alpha-1, ... | | Authors: | Zeytuni, N, Yang, Z, Odeh-Ahmed, A, Abdoli, A, Leyton, V.J, Bednova, O, Lavigne, P, Lemieux, B. | | Deposit date: | 2024-07-10 | | Release date: | 2025-09-03 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | Probing the extent of importin-alpha targeting of the TAF8 NLS by eliminating its cationic net-charge.
Protein Sci., 34, 2025
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7W6O
 | | Crystal structure of a PSH1 in complex with J1K | | Descriptor: | 4-(2-hydroxyethylcarbamoyl)benzoic acid, PSH1 | | Authors: | Gao, J, Lara, P, Li, Z.S, Han, X, Wei, R, Liu, W.D. | | Deposit date: | 2021-12-02 | | Release date: | 2022-09-14 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Multiple Substrate Binding Mode-Guided Engineering of a Thermophilic PET Hydrolase.
Acs Catalysis, 12, 2022
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9C1S
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7W6Q
 | | Crystal structure of a PSH1 in complex with ligand J1K | | Descriptor: | 4-(2-hydroxyethylcarbamoyl)benzoic acid, PSH1 | | Authors: | Gao, J, Lara, P, Li, Z.S, Han, X, Wei, R, Liu, W.D. | | Deposit date: | 2021-12-02 | | Release date: | 2022-09-14 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Multiple Substrate Binding Mode-Guided Engineering of a Thermophilic PET Hydrolase.
Acs Catalysis, 12, 2022
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5KWR
 | | Crystal structure of rat Cerebellin-1 | | Descriptor: | Cerebellin-1, alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Cheng, S, Ozkan, E. | | Deposit date: | 2016-07-18 | | Release date: | 2016-08-03 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.795 Å) | | Cite: | Conformational Plasticity in the Transsynaptic Neurexin-Cerebellin-Glutamate Receptor Adhesion Complex.
Structure, 24, 2016
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7QCH
 | | Structure of SARS-CoV-2 Papain-like Protease bound to N-(3,5-dimethoxy-4-hydroxybenzyliden)thiosemicarbazone | | Descriptor: | CHLORIDE ION, GLYCEROL, N-(3,5-dimetoxy-4-hydroxybenzyliden)thiosemicarbazone, ... | | Authors: | Ewert, W, Gunther, S, Reinke, P, Falke, S, Lieske, J, Miglioli, F, Carcelli, M, Srinivasan, V, Betzel, C, Han, H, Lorenzen, K, Guenther, C, Niebling, S, Garcia-Alai, M, Hinrichs, W, Rogolino, D, Meents, A. | | Deposit date: | 2021-11-24 | | Release date: | 2022-03-16 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Hydrazones and Thiosemicarbazones Targeting Protein-Protein-Interactions of SARS-CoV-2 Papain-like Protease.
Front Chem, 10, 2022
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7QCM
 | | Structure of SARS-CoV-2 Papain-like Protease bound to N-(3-methoxy-4-hydroxy-acetophenone)thiosemicarbazone | | Descriptor: | CHLORIDE ION, GLYCEROL, N-(3-metoxy-4-hydroxy-acetophenone)thiosemicarbazone, ... | | Authors: | Ewert, W, Gunther, S, Reinke, P, Falke, S, Lieske, J, Miglioli, F, Carcelli, M, Srinivasan, V, Betzel, C, Han, H, Lorenzen, K, Guenther, C, Niebling, S, Garcia-Alai, M, Hinrichs, W, Rogolino, D, Meents, A. | | Deposit date: | 2021-11-24 | | Release date: | 2022-03-16 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Hydrazones and Thiosemicarbazones Targeting Protein-Protein-Interactions of SARS-CoV-2 Papain-like Protease.
Front Chem, 10, 2022
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9CLG
 | | Importin alpha isoform 2 with synthetic zero net-charge nuclear localization signal | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, Importin subunit alpha-1, ... | | Authors: | Zeytuni, N, Yang, Z, Odeh-Ahmed, A, Abdoli, A, Leyton, V.J, Bednova, O, Lavigne, P, Lemieux, B. | | Deposit date: | 2024-07-11 | | Release date: | 2025-09-03 | | Method: | X-RAY DIFFRACTION (2.42 Å) | | Cite: | Probing the extent of importin-alpha targeting of the TAF8 NLS by eliminating its cationic net-charge.
Protein Sci., 34, 2025
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9CFD
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7WJZ
 | | Omicron Spike bitrimer with 6m6 antibody | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6m6 heavy chain, 6m6 light chain, ... | | Authors: | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | | Deposit date: | 2022-01-08 | | Release date: | 2022-07-13 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.34 Å) | | Cite: | A broadly neutralizing antibody against SARS-CoV-2 Omicron variant infection exhibiting a novel trimer dimer conformation in spike protein binding.
Cell Res., 32, 2022
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9C73
 | | Hybrid G-quadruplex from Tetrahymena thermophila telomeric sequence in complex with TrisQO | | Descriptor: | (5S)-6-oxo-6H-dipyrido[1,2-b:1',2'-j]quinolizino[3,2-f][2,8]phenanthroline-12,19-diium, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... | | Authors: | Ali, A, Yatsunyk, L.A. | | Deposit date: | 2024-06-10 | | Release date: | 2025-08-27 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | Hybrid G-quadruplex from Tetrahymena thermophila telomeric sequence in complex with triangular star shaped TrisQ ligand
To Be Published
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2HUQ
 | | Crystal structure of PH0725 from Pyrococcus horikoshii OT3 | | Descriptor: | PLATINUM (II) ION, Probable diphthine synthase, S-ADENOSYL-L-HOMOCYSTEINE | | Authors: | Sugahara, M, Karthe, P, Kumarevel, T.S, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-07-27 | | Release date: | 2007-01-27 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of PH0725 from Pyrococcus horikoshii OT3
To be Published
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2HUN
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