3FUV
 
 | | Apo-form of T. thermophilus 16S rRNA A1518 and A1519 methyltransferase (KsgA) in space group P43212 | | Descriptor: | Dimethyladenosine transferase | | Authors: | Demirci, H, Belardinelli, R, Seri, E, Gregory, S.T, Gualerzi, C, Dahlberg, A.E, Jogl, G. | | Deposit date: | 2009-01-14 | | Release date: | 2009-03-31 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural rearrangements in the active site of the Thermus thermophilus 16S rRNA methyltransferase KsgA in a binary complex with 5'-methylthioadenosine.
J.Mol.Biol., 388, 2009
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4MQ9
 | | Crystal structure of Thermus thermophilus RNA polymerase holoenzyme in complex with GE23077 | | Descriptor: | (2Z)-2-methylbut-2-enoic acid, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | Authors: | Ho, M.X, Arnold, E, Ebright, R.H, Zhang, Y, Tuske, S. | | Deposit date: | 2013-09-16 | | Release date: | 2014-05-07 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides.
Elife, 3, 2014
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3OLB
 | | Poliovirus polymerase elongation complex with 2',3'-dideoxy-ctp | | Descriptor: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, ISOPROPYL ALCOHOL, Polymerase, ... | | Authors: | Gong, P, Peersen, O.B. | | Deposit date: | 2010-08-25 | | Release date: | 2010-12-22 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.USA, 107, 2010
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2B2G
 | | MS2 Wild-type RNA stemloop complexed with an N87S mutant MS2 capsid | | Descriptor: | 5'-R(*AP*CP*AP*UP*GP*AP*GP*GP*AP*UP*UP*AP*CP*CP*CP*AP*UP*GP*U)-3', Coat protein | | Authors: | Horn, W.T, Tars, K, Grahn, E, Helgstrand, C, Baron, A.J, Lago, H, Adams, C.J, Peabody, D.S, Phillips, S.E.V, Stonehouse, N.J, Liljas, L, Stockley, P.G. | | Deposit date: | 2005-09-19 | | Release date: | 2006-05-09 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.02 Å) | | Cite: | Structural basis of RNA binding discrimination between bacteriophages Qbeta and MS2
Structure, 14, 2006
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1KHV
 | | Crystal Structure of Rabbit Hemorrhagic Disease Virus RNA-dependent RNA polymerase complexed with Lu3+ | | Descriptor: | LUTETIUM (III) ION, RNA-DIRECTED RNA POLYMERASE | | Authors: | Ng, K.K, Cherney, M.M, Vazquez, A.L, Machin, A, Alonso, J.M, Parra, F, James, M.N. | | Deposit date: | 2001-12-01 | | Release date: | 2002-01-16 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase.
J.Biol.Chem., 277, 2002
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3OL6
 | | Poliovirus polymerase elongation complex | | Descriptor: | ISOPROPYL ALCOHOL, Polymerase, RNA (5'-R(*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*GP*UP*CP*CP*GP*GP*AP*AP*A)-3'), ... | | Authors: | Gong, P, Peersen, O.B. | | Deposit date: | 2010-08-25 | | Release date: | 2010-12-22 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.USA, 107, 2010
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2E29
 | | Solution structure of the GUCT domain from human ATP-dependent RNA helicase DDX50, DEAD box protein 50 | | Descriptor: | ATP-dependent RNA helicase DDX50 | | Authors: | Ohnishi, S, Paakkonen, K, Guntert, P, Sato, M, Koshiba, S, Harada, T, Watanabe, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-11-10 | | Release date: | 2007-05-15 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the GUCT domain from human RNA helicase II/Gubeta reveals the RRM fold, but implausible RNA interactions
Proteins, 74, 2008
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3DMG
 | | T. Thermophilus 16S rRNA N2 G1207 methyltransferase (RsmC) in complex with AdoHcy | | Descriptor: | Probable ribosomal RNA small subunit methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION | | Authors: | Demirci, H, Gregory, S.T, Dahlberg, A.E, Jogl, G. | | Deposit date: | 2008-07-01 | | Release date: | 2008-07-29 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Crystal Structure of the Thermus thermophilus 16 S rRNA Methyltransferase RsmC in Complex with Cofactor and Substrate Guanosine.
J.Biol.Chem., 283, 2008
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6G3B
 | | AvaII restriction endonuclease in complex with an RNA/DNA hybrid | | Descriptor: | DNA (5'-D(*CP*CP*AP*TP*GP*GP*TP*CP*CP*TP*A)-3'), RNA (5'-R(P*GP*UP*AP*GP*GP*AP*CP*CP*AP*UP*G)-3'), Type II site-specific deoxyribonuclease | | Authors: | Kisiala, M, Kowalska, M, Czapinska, H, Bochtler, M. | | Deposit date: | 2018-03-24 | | Release date: | 2019-04-10 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Restriction endonucleases that cleave RNA/DNA heteroduplexes bind dsDNA in A-like conformation
Nucleic Acids Res., 2020
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4PUQ
 | | Mus Musculus Tdp2 reaction product complex with 5'-phosphorylated RNA/DNA, glycerol, and Mg2+ | | Descriptor: | ACETATE ION, DNA/RNA hybrid, GLYCEROL, ... | | Authors: | Schellenberg, M.J, Williams, R.S. | | Deposit date: | 2014-03-13 | | Release date: | 2014-05-14 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Proteolytic Degradation of Topoisomerase II (Top2) Enables the Processing of Top2DNA and Top2RNA Covalent Complexes by Tyrosyl-DNA-Phosphodiesterase 2 (TDP2).
J.Biol.Chem., 289, 2014
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2FEY
 | | The structure of stem loop IV of Tetrahymena telomerase RNA | | Descriptor: | stem-loop IV of Tetrahymena telomerase RNA | | Authors: | Chen, Y, Fender, J, Legassie, J.D, Jarstfer, M.B, Bryan, T.M, Varani, G. | | Deposit date: | 2005-12-16 | | Release date: | 2006-06-27 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structure of stem-loop IV of Tetrahymena telomerase RNA.
Embo J., 25, 2006
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3OL9
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3OL7
 | | Poliovirus polymerase elongation complex with CTP | | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, ISOPROPYL ALCOHOL, ... | | Authors: | Gong, P, Peersen, O.B. | | Deposit date: | 2010-08-25 | | Release date: | 2010-12-22 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.USA, 107, 2010
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1WSF
 | | Co-crystal structure of E.coli RNase HI active site mutant (D134A*) with Mn2+ | | Descriptor: | MANGANESE (II) ION, Ribonuclease HI | | Authors: | Tsunaka, Y, Takano, K, Matsumura, H, Yamagata, Y, Kanaya, S. | | Deposit date: | 2004-11-05 | | Release date: | 2005-02-08 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Identification of Single Mn(2+) Binding Sites Required for Activation of the Mutant Proteins of E.coli RNase HI at Glu48 and/or Asp134 by X-ray Crystallography
J.Mol.Biol., 345, 2005
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6HYP
 | | Rea1 Wild type ADP state (AAA+ ring part) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Midasin,Midasin | | Authors: | Sosnowski, P, Urnavicius, L, Boland, A, Fagiewicz, R, Busselez, J, Papai, G, Schmidt, H. | | Deposit date: | 2018-10-22 | | Release date: | 2018-12-12 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | The CryoEM structure of the Saccharomyces cerevisiae ribosome maturation factor Rea1.
Elife, 7, 2018
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6I26
 | | Rea1 Wild type AMPPNP state | | Descriptor: | Midasin,Midasin,Midasin,Midasin | | Authors: | Sosnowski, P, Urnavicius, L, Boland, A, Fagiewicz, R, Busselez, J, Papai, G, Schmidt, H. | | Deposit date: | 2018-10-31 | | Release date: | 2018-12-12 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | The CryoEM structure of the Saccharomyces cerevisiae ribosome maturation factor Rea1.
Elife, 7, 2018
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1WSE
 | | Co-crystal structure of E.coli RNase HI active site mutant (E48A*) with Mn2+ | | Descriptor: | MANGANESE (II) ION, Ribonuclease HI | | Authors: | Tsunaka, Y, Takano, K, Matsumura, H, Yamagata, Y, Kanaya, S. | | Deposit date: | 2004-11-05 | | Release date: | 2005-02-08 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Identification of Single Mn(2+) Binding Sites Required for Activation of the Mutant Proteins of E.coli RNase HI at Glu48 and/or Asp134 by X-ray Crystallography
J.Mol.Biol., 345, 2005
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5HY7
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6I27
 | | Rea1 AAA2L-H2alpha deletion mutant in AMPPNP State | | Descriptor: | Midasin,Midasin,Midasin,Midasin,Midasin,Midasin,Midasin | | Authors: | Sosnowski, P, Urnavicius, L, Boland, A, Fagiewicz, R, Busselez, J, Papai, G, Schmidt, H. | | Deposit date: | 2018-10-31 | | Release date: | 2018-12-12 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (7.8 Å) | | Cite: | The CryoEM structure of the Saccharomyces cerevisiae ribosome maturation factor Rea1.
Elife, 7, 2018
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1WSG
 | | Co-crystal structure of E.coli RNase HI active site mutant (E48A/D134N*) with Mn2+ | | Descriptor: | MANGANESE (II) ION, Ribonuclease HI | | Authors: | Tsunaka, Y, Takano, K, Matsumura, H, Yamagata, Y, Kanaya, S. | | Deposit date: | 2004-11-05 | | Release date: | 2005-02-08 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Identification of Single Mn(2+) Binding Sites Required for Activation of the Mutant Proteins of E.coli RNase HI at Glu48 and/or Asp134 by X-ray Crystallography
J.Mol.Biol., 345, 2005
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4B17
 | | Crystal structure of C2498 2'-O-ribose methyltransferase RlmM from Escherichia coli in complex with S-adenosylmethionine | | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE M, ... | | Authors: | Punekar, A.S, Shepherd, T.R, Liljeruhm, J, Forster, A.C, Selmer, M. | | Deposit date: | 2012-07-07 | | Release date: | 2012-08-15 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal Structure of Rlmm, the 2'O-Ribose Methyltransferase for C2498 of Escherichia Coli 23S Rrna.
Nucleic Acids Res., 40, 2012
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2DD3
 | | An alternating sheared AA pair in 5'GGUGAAGGCU/3'PCCGAAGCCG: II. The minor conformation with A6/A5/A16 stack | | Descriptor: | 5'-R(*GP*CP*CP*GP*AP*AP*GP*CP*CP*(P5P))-3', 5'-R(*GP*GP*UP*GP*AP*AP*GP*GP*CP*U)-3' | | Authors: | Chen, G, Kennedy, S.D, Krugh, T.R, Turner, D.H. | | Deposit date: | 2006-01-19 | | Release date: | 2006-06-13 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | An Alternating Sheared AA Pair and Elements of Stability for a Single Sheared Purine-Purine Pair Flanked by Sheared GA Pairs in RNA
Biochemistry, 45, 2006
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2DD2
 | | An alternating sheared AA pair in 5'GGUGAAGGCU/3'PCCGAAGCCG: I. The major conformation with A6/A15/A16 stack | | Descriptor: | 5'-R(*GP*CP*CP*GP*AP*AP*GP*CP*CP*(P5P))-3', 5'-R(*GP*GP*UP*GP*AP*AP*GP*GP*CP*U)-3' | | Authors: | Chen, G, Kennedy, S.D, Krugh, T.R, Turner, D.H. | | Deposit date: | 2006-01-19 | | Release date: | 2006-06-13 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | An Alternating Sheared AA Pair and Elements of Stability for a Single Sheared Purine-Purine Pair Flanked by Sheared GA Pairs in RNA
Biochemistry, 45, 2006
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2JLF
 | | STRUCTURAL EXPLANATION FOR THE ROLE OF MN IN THE ACTIVITY OF PHI6 RNA- DEPENDENT RNA POLYMERASE | | Descriptor: | MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | | Authors: | Poranen, M.M, Salgado, P.S, Koivunen, M.R.L, Wright, S, Bamford, D.H, Stuart, D.I, Grimes, J.M. | | Deposit date: | 2008-09-08 | | Release date: | 2008-11-04 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural Explanation for the Role of Mn2+ in the Activity of {Phi}6 RNA-Dependent RNA Polymerase.
Nucleic Acids Res., 36, 2008
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6F4A
 | | Yeast mitochondrial RNA degradosome complex mtEXO | | Descriptor: | Exoribonuclease II, mitochondrial, RNA (5'-R(P*AP*GP*AP*UP*AP*C)-3'), ... | | Authors: | Razew, M, Nowak, E, Nowotny, M. | | Deposit date: | 2017-11-29 | | Release date: | 2018-01-17 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.55 Å) | | Cite: | Structural analysis of mtEXO mitochondrial RNA degradosome reveals tight coupling of nuclease and helicase components.
Nat Commun, 9, 2018
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