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6MSL	Integrin AlphaVBeta3 ectodomain bound to EETI-II 2.5D Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cystine Knot Protein 2.5D, ... Authors: van Agthoven, J.F, Arnaout, M.A. Deposit date: 2018-10-16 Release date: 2019-10-23 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.104 Å) Cite: Structural Basis of the Differential Binding of Engineered Knottins to Integrins alpha V beta 3 and alpha 5 beta 1. Structure, 27, 2019
4MMZ	Integrin AlphaVBeta3 ectodomain bound to an antagonistic tenth domain of Fibronectin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fibronectin, ... Authors: van Agthoven, J, Xiong, J, Arnaout, M.A. Deposit date: 2013-09-09 Release date: 2014-03-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structural basis for pure antagonism of integrin alpha V beta 3 by a high-affinity form of fibronectin. Nat.Struct.Mol.Biol., 21, 2014
4O02	AlphaVBeta3 integrin in complex with monoclonal antibody FAB fragment. Descriptor: 17E6 heavy chain, 17E6 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Mahalingam, B, van Agthoven, J, Xiong, J, Arnaout, M.A. Deposit date: 2013-12-13 Release date: 2014-04-02 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (3.605 Å) Cite: Atomic basis for the species-specific inhibition of alpha V integrins by monoclonal antibody 17E6 is revealed by the crystal structure of alpha V beta 3 ectodomain-17E6 Fab complex. J.Biol.Chem., 289, 2014
6NAJ	Integrin AlphaVBeta3 ectodomain bound to Hr10 variant of the 10th domain of Fibronectin. Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fibronectin, ... Authors: van Agthoven, J, Arnaout, M.A. Deposit date: 2018-12-05 Release date: 2019-12-11 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structure-guided design of pure orthosteric inhibitors of alpha IIb beta 3 that prevent thrombosis but preserve hemostasis. Nat Commun, 11, 2020
4MMY	Integrin AlphaVBeta3 ectodomain bound to the tenth domain of Fibronectin with the IAKGDWND motif Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fibronectin, ... Authors: van Agthoven, J, Xiong, J, Arnaout, M.A. Deposit date: 2013-09-09 Release date: 2014-03-26 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (3.183 Å) Cite: Structural basis for pure antagonism of integrin alpha V beta 3 by a high-affinity form of fibronectin. Nat.Struct.Mol.Biol., 21, 2014

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