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2MPQ
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BU of 2mpq by Molmil
Solution structure of the sodium channel toxin Hd1a
Descriptor: Hd1a
Authors:Klint, J.K, Mobli, M, King, G.F.
Deposit date:2014-06-01
Release date:2015-03-25
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Seven novel modulators of the analgesic target NaV 1.7 uncovered using a high-throughput venom-based discovery approach.
Br.J.Pharmacol., 172, 2015
2M4X
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BU of 2m4x by Molmil
Analysis of the structural and molecular basis of voltage-sensitive sodium channel inhibition by the spider toxin, Huwentoxin-IV (-TRTX-Hh2a).
Descriptor: Mu-theraphotoxin-Hh2a
Authors:Gibbs, A, Flinspach, M.
Deposit date:2013-02-11
Release date:2013-06-19
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Analysis of the Structural and Molecular Basis of Voltage-sensitive Sodium Channel Inhibition by the Spider Toxin Huwentoxin-IV ( mu-TRTX-Hh2a).
J.Biol.Chem., 288, 2013
2M4Z
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BU of 2m4z by Molmil
Analysis of the structural and molecular basis of voltage-sensitive sodium channel inhibition by the spider toxin, Huwentoxin-IV (-TRTX-Hh2a).
Descriptor: Mu-theraphotoxin-Hh2a
Authors:Gibbs, A.
Deposit date:2013-02-12
Release date:2013-06-19
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Analysis of the Structural and Molecular Basis of Voltage-sensitive Sodium Channel Inhibition by the Spider Toxin Huwentoxin-IV ( mu-TRTX-Hh2a).
J.Biol.Chem., 288, 2013
3J5Q
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BU of 3j5q by Molmil
Structure of TRPV1 ion channel in complex with DkTx and RTX determined by single particle electron cryo-microscopy
Descriptor: Kappa-theraphotoxin-Cg1a 1, Transient receptor potential cation channel subfamily V member 1
Authors:Liao, M, Cao, E, Julius, D, Cheng, Y.
Deposit date:2013-10-28
Release date:2013-12-04
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:TRPV1 structures in distinct conformations reveal activation mechanisms.
Nature, 504, 2013
7K48
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BU of 7k48 by Molmil
Structure of NavAb/Nav1.7-VS2A chimera trapped in the resting state by tarantula toxin m3-Huwentoxin-IV
Descriptor: Maltose/maltodextrin-binding periplasmic protein,Ion transport protein,Sodium channel protein type 9 subunit alpha chimera, Mu-theraphotoxin-Hs2a
Authors:Wisedchaisri, G, Tonggu, L, Gamal El-Din, T.M, McCord, E, Zheng, N, Catterall, W.A.
Deposit date:2020-09-15
Release date:2020-12-02
Last modified:2021-01-20
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural Basis for High-Affinity Trapping of the Na V 1.7 Channel in Its Resting State by Tarantula Toxin.
Mol.Cell, 81, 2021
6W6O
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BU of 6w6o by Molmil
NaChBac-Nav1.7VSDII chimera and HWTX-IV complex
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Huwentoxin-IV, NaChBac-Nav1.7VSDII chimera
Authors:Yan, N, Gao, S.
Deposit date:2020-03-17
Release date:2020-06-24
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na + channels in nanodisc.
Proc.Natl.Acad.Sci.USA, 117, 2020
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数据于2024-06-12公开中

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