2N6O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2n6o by Molmil](/molmil-images/mine/2n6o) | |
2M4X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2m4x by Molmil](/molmil-images/mine/2m4x) | |
2M50
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2m50 by Molmil](/molmil-images/mine/2m50) | Analysis of the structural and molecular basis of voltage-sensitive sodium channel inhibition by the spider toxin, Huwentoxin-IV (-TRTX-Hh2a). | Descriptor: | Mu-theraphotoxin-Hh2a | Authors: | Gibbs, A, Minassian, N, Flinspach, M, Wickenden, A. | Deposit date: | 2013-02-12 | Release date: | 2013-06-19 | Last modified: | 2023-11-29 | Method: | SOLUTION NMR | Cite: | Analysis of the Structural and Molecular Basis of Voltage-sensitive Sodium Channel Inhibition by the Spider Toxin Huwentoxin-IV ( mu-TRTX-Hh2a). J.Biol.Chem., 288, 2013
|
|
6W6O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6w6o by Molmil](/molmil-images/mine/6w6o) | NaChBac-Nav1.7VSDII chimera and HWTX-IV complex | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Huwentoxin-IV, NaChBac-Nav1.7VSDII chimera | Authors: | Yan, N, Gao, S. | Deposit date: | 2020-03-17 | Release date: | 2020-06-24 | Last modified: | 2021-01-13 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na + channels in nanodisc. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
7K48
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k48 by Molmil](/molmil-images/mine/7k48) | Structure of NavAb/Nav1.7-VS2A chimera trapped in the resting state by tarantula toxin m3-Huwentoxin-IV | Descriptor: | Maltose/maltodextrin-binding periplasmic protein,Ion transport protein,Sodium channel protein type 9 subunit alpha chimera, Mu-theraphotoxin-Hs2a | Authors: | Wisedchaisri, G, Tonggu, L, Gamal El-Din, T.M, McCord, E, Zheng, N, Catterall, W.A. | Deposit date: | 2020-09-15 | Release date: | 2020-12-02 | Last modified: | 2021-01-20 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural Basis for High-Affinity Trapping of the Na V 1.7 Channel in Its Resting State by Tarantula Toxin. Mol.Cell, 81, 2021
|
|
3J5Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3j5q by Molmil](/molmil-images/mine/3j5q) | Structure of TRPV1 ion channel in complex with DkTx and RTX determined by single particle electron cryo-microscopy | Descriptor: | Kappa-theraphotoxin-Cg1a 1, Transient receptor potential cation channel subfamily V member 1 | Authors: | Liao, M, Cao, E, Julius, D, Cheng, Y. | Deposit date: | 2013-10-28 | Release date: | 2013-12-04 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | TRPV1 structures in distinct conformations reveal activation mechanisms. Nature, 504, 2013
|
|