PDB: 424 resultsInfo pagesStatus searchChemie searchBIRD

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2YB6	Native human Rad6 Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, UBIQUITIN-CONJUGATING ENZYME E2 B Authors: Hibbert, R.G, Sixma, T.K. Deposit date: 2011-03-02 Release date: 2011-04-20 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: E3 Ligase Rad18 Promotes Monoubiquitination Rather Than Ubiquitin Chain Formation by E2 Enzyme Rad6. Proc.Natl.Acad.Sci.USA, 108, 2011
2YBF	Complex of Rad18 (Rad6 binding domain) with Rad6b Descriptor: BETA-MERCAPTOETHANOL, E3 UBIQUITIN-PROTEIN LIGASE RAD18, SODIUM ION, ... Authors: Hibbert, R.G, Sixma, T.K. Deposit date: 2011-03-08 Release date: 2011-04-20 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2 Å) Cite: E3 Ligase Rad18 Promotes Monoubiquitination Rather Than Ubiquitin Chain Formation by E2 Enzyme Rad6. Proc.Natl.Acad.Sci.USA, 108, 2011
3E95	Crystal Structure of the Plasmodium Falciparum ubiquitin conjugating enzyme complex, PfUBC13-PfUev1a Descriptor: UNKNOWN ATOM OR ION, Ubiquitin carrier protein, Ubiquitin-conjugating enzyme E2 Authors: Wernimont, A.K, Lam, A, Ali, A, Brokx, S, Lin, Y.H, Zhao, Y, Lew, J, Ravichandran, M, Wasney, G, Vedadi, M, Kozieradzki, I, Schapira, M, Bochkarev, A, Wilkstrom, M, BOuntra, C, Arrowsmith, C.H, Edwards, A.M, Hui, R, Qiu, W, Brand, V.B, Structural Genomics Consortium (SGC) Deposit date: 2008-08-21 Release date: 2008-09-30 Last modified: 2017-10-25 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal Structure of the Plasmodium Falciparum ubiquitin conjugating enzyme complex, PfUBC13-PfUev1a TO BE PUBLISHED
3WE5	Crystal structure of ubiquitin conjugating enzyme E2 UbcA1 from Agrocybe aegerita Descriptor: ACETIC ACID, GLYCEROL, Ubiquitin conjugating enzyme Authors: Li, D.F, Feng, L, Wang, D.C, Liu, W. Deposit date: 2013-07-01 Release date: 2014-07-09 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structure of ubiquitin conjugating enzyme E2 UbcA1 from Agrocybe aegerita To be Published
2Z5D	Human ubiquitin-conjugating enzyme E2 H Descriptor: SODIUM ION, Ubiquitin-conjugating enzyme E2 H Authors: Bochkarev, A, Cui, H, Walker, J.R, Newman, E.M, Mackenzie, F, Battaile, K.P, Sundstrom, M, Arrowsmith, C, Edwards, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) Deposit date: 2007-07-06 Release date: 2007-10-09 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. MOL.CELL PROTEOMICS, 11, 2012
6CYR	Crystal structure of the UBE2A variant Q93E Descriptor: Ubiquitin-conjugating enzyme E2 A Authors: Ranzani, A.T, de Oliveira, J.F. Deposit date: 2018-04-06 Release date: 2018-12-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Mechanistic insights revealed by a UBE2A mutation linked to intellectual disability. Nat. Chem. Biol., 15, 2019
5V0R	Crystal structure of ubiquitin-conjugating enzyme from Naegleria fowleri with modified Cys99 Descriptor: CHLORIDE ION, MAGNESIUM ION, Ubiquitin-conjugating enzyme Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2017-02-28 Release date: 2017-03-29 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Crystal structure of ubiquitin-conjugating enzyme from Naegleria fowleri with modified Cys99 to be published
6CYO	Crystal structure of human UBE2A (RAD6A) Descriptor: Ubiquitin-conjugating enzyme E2 A Authors: Ranzani, A.T, de Oliveira, J.F. Deposit date: 2018-04-06 Release date: 2018-12-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Mechanistic insights revealed by a UBE2A mutation linked to intellectual disability. Nat. Chem. Biol., 15, 2019
3BZH	Crystal structure of human ubiquitin-conjugating enzyme E2 E1 Descriptor: GLYCEROL, Ubiquitin-conjugating enzyme E2 E1 Authors: Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) Deposit date: 2008-01-18 Release date: 2008-02-26 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.6 Å) Cite: A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. Mol Cell Proteomics, 11, 2012
4FH1	S. cerevisiae Ubc13-N79A Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Ubiquitin-conjugating enzyme E2 13 Authors: Berndsen, C.E, Wolberger, C, Wiener, R. Deposit date: 2012-06-05 Release date: 2013-01-09 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.61 Å) Cite: A conserved asparagine has a structural role in ubiquitin-conjugating enzymes. Nat.Chem.Biol., 9, 2013
4DS2	Ubiquitin conjugating enzyme (putative) from Trypanosoma cruzi Descriptor: Ubiquitin-conjugating enzyme E2, putative Authors: Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) Deposit date: 2012-02-17 Release date: 2012-02-29 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.63 Å) Cite: Ubiquitin conjugating enzyme (putative) from Trypanosoma cruzi To be Published
7AHF	Dimeric structure of the catalytic domain of the human ubiquitin-conjugating enzyme UBE2S L114E varaiant Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Ubiquitin-conjugating enzyme E2 S Authors: Liess, A.K.L, Feiler, C.G, Lorenz, S. Deposit date: 2020-09-24 Release date: 2021-10-06 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Structural analyses of the ubiquitin-conjugating enzyme UBE2S in different crystal forms To Be Published
7BOL	ubiquitin-conjugating enzyme, Ube2D2 Descriptor: Ubiquitin-conjugating enzyme E2 D2 Authors: Lee, S.O, Ryu, K.S, Chi, S.-W. Deposit date: 2020-03-19 Release date: 2021-03-24 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.797 Å) Cite: MUL1-RING recruits the substrate, p53-TAD as a complex with UBE2D2-UB conjugate. Febs J., 2022
3RZ3	Human Cdc34 E2 in complex with CC0651 inhibitor Descriptor: 4,5-dideoxy-5-(3',5'-dichlorobiphenyl-4-yl)-4-[(methoxyacetyl)amino]-L-arabinonic acid, Ubiquitin-conjugating enzyme E2 R1 Authors: Ceccarelli, D.F, Webb, D.R, Sicheri, F. Deposit date: 2011-05-11 Release date: 2011-07-06 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: An allosteric inhibitor of the human cdc34 ubiquitin conjugating enzyme Cell(Cambridge,Mass.), 145, 2011
3TGD	Crystal structure of the human ubiquitin-conjugating enzyme (E2) UbcH5b Descriptor: Ubiquitin-conjugating enzyme E2 D2 Authors: Page, R.C, Amick, J, Misra, S. Deposit date: 2011-08-17 Release date: 2011-08-31 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of the human ubiquitin-conjugating enzyme (E2) UbcH5b To be Published
4NRG	Crystal Structure of a human Mms2/Ubc13 D118G mutant Descriptor: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2 Authors: Hodge, C.D, Edwards, R.A, Glover, J.N.M. Deposit date: 2013-11-26 Release date: 2014-12-10 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes. J.Am.Chem.Soc., 136, 2014
4M1N	Crystal structure of Plasmodium falciparum ubiquitin conjugating enzyme UBC9 Descriptor: SODIUM ION, Ubiquitin conjugating enzyme UBC9 Authors: Boucher, L.E, Reiter, K.H, Bosch, J, Matunis, J.M. Deposit date: 2013-08-03 Release date: 2013-08-21 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Identification of Biochemically Distinct Properties of the Small Ubiquitin-related Modifier (SUMO) Conjugation Pathway in Plasmodium falciparum. J.Biol.Chem., 288, 2013
7LEW	Crystal structure of UBE2G2 in complex with the UBE2G2-binding region of AUP1 Descriptor: Lipid droplet-regulating VLDL assembly factor AUP1, Ubiquitin-conjugating enzyme E2 G2 Authors: Liang, Y.-H, Smith, C.E, Tsai, Y.C, Weissman, A.M, Ji, X. Deposit date: 2021-01-15 Release date: 2021-11-10 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.736 Å) Cite: A structurally conserved site in AUP1 binds the E2 enzyme UBE2G2 and is essential for ER-associated degradation. Plos Biol., 19, 2021
4ONM	Crystal structure of human Mms2/Ubc13 - NSC697923 Descriptor: 2-[(4-methylphenyl)sulfonyl]-5-nitrofuran, GLYCEROL, Ubiquitin-conjugating enzyme E2 N, ... Authors: Hodge, C.D, Edwards, R.A, Glover, J.N.M. Deposit date: 2014-01-28 Release date: 2015-05-06 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting. Acs Chem.Biol., 10, 2015
4ONN	Crystal structure of human Mms2/Ubc13 - BAY 11-7082 Descriptor: 3-[(4-methylphenyl)sulfonyl]prop-2-enenitrile, GLYCEROL, Ubiquitin-conjugating enzyme E2 N, ... Authors: Hodge, C.D, Edwards, R.A, Glover, J.N.M. Deposit date: 2014-01-28 Release date: 2015-05-06 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting. Acs Chem.Biol., 10, 2015
4ONL	Crystal structure of human Mms2/Ubc13_D81N, R85S, A122V, N123P Descriptor: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2 Authors: Hodge, C.D, Edwards, R.A, Glover, J.N.M. Deposit date: 2014-01-28 Release date: 2015-05-06 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting. Acs Chem.Biol., 10, 2015
4NR3	Crystal Structure of a human Mms2/Ubc13 L121G mutant Descriptor: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2 Authors: Hodge, C.D, Edwards, R.A, Glover, J.N.M. Deposit date: 2013-11-26 Release date: 2014-12-10 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.802 Å) Cite: Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes. J.Am.Chem.Soc., 136, 2014
4NRI	Crystal Structure of a human Mms2/Ubc13 A122G mutant Descriptor: GLYCEROL, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2 Authors: Hodge, C.D, Edwards, R.A, Glover, J.N.M. Deposit date: 2013-11-26 Release date: 2014-12-10 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes. J.Am.Chem.Soc., 136, 2014
6S98	Crystal structure of the catalytic domain of UBE2S WT. Descriptor: 1,2-ETHANEDIOL, ACETATE ION, SODIUM ION, ... Authors: Liess, A.K.L, Lorenz, S. Deposit date: 2019-07-11 Release date: 2020-10-21 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Dimerization regulates the human APC/C-associated ubiquitin-conjugating enzyme UBE2S. Sci.Signal., 13, 2020
6S96	Crystal structure of the catalytic domain of UBE2S C118A. Descriptor: FORMIC ACID, SODIUM ION, Ubiquitin-conjugating enzyme E2 S Authors: Liess, A.K.L, Lorenz, S. Deposit date: 2019-07-11 Release date: 2020-10-21 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.18 Å) Cite: Dimerization regulates the human APC/C-associated ubiquitin-conjugating enzyme UBE2S. Sci.Signal., 13, 2020

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