1KZG
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![BU of 1kzg by Molmil](/molmil-images/mine/1kzg) | DbsCdc42(Y889F) | Descriptor: | CDC42 HOMOLOG, GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS | Authors: | Rossman, K.L, Worthylake, D.K, Snyder, J.T, Siderovski, D.P, Campbell, S.L, Sondek, J. | Deposit date: | 2002-02-06 | Release date: | 2002-03-20 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange. EMBO J., 21, 2002
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7PQH
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![BU of 7pqh by Molmil](/molmil-images/mine/7pqh) | Cryo-EM structure of Saccharomyces cerevisiae TOROID (TORC1 Organized in Inhibited Domains). | Descriptor: | Serine/threonine-protein kinase TOR2, Target of rapamycin complex 1 subunit KOG1,Target of rapamycin complex 1 subunit Kog1, Target of rapamycin complex subunit LST8 | Authors: | Felix, J, Prouteau, M, Bourgoint, C, Bonadei, L, Desfosses, A, Gabus, C, Sadian, Y, Savvides, S.N, Gutsche, I, Loewith, R. | Deposit date: | 2021-09-17 | Release date: | 2023-01-18 | Last modified: | 2023-03-29 | Method: | ELECTRON MICROSCOPY (3.87 Å) | Cite: | EGOC inhibits TOROID polymerization by structurally activating TORC1. Nat.Struct.Mol.Biol., 30, 2023
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1MYO
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![BU of 1myo by Molmil](/molmil-images/mine/1myo) | SOLUTION STRUCTURE OF MYOTROPHIN, NMR, 44 STRUCTURES | Descriptor: | MYOTROPHIN | Authors: | Yang, Y, Nanduri, S, Sen, S, Qin, J. | Deposit date: | 1998-08-17 | Release date: | 1999-08-17 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The structural basis of ankyrin-like repeat function as revealed by the solution structure of myotrophin. Structure, 6, 1998
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2BJR
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![BU of 2bjr by Molmil](/molmil-images/mine/2bjr) | Crystal structure of the nematode sperm cell motility protein MFP2B | Descriptor: | MFP2B, SULFATE ION, ZINC ION | Authors: | Grant, R.P, Buttery, S.M, Ekman, G.C, Roberts, T.M, Stewart, M. | Deposit date: | 2005-02-07 | Release date: | 2005-03-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of Mfp2 and its Function in Enhancing Msp Polymerization in Ascaris Sperm Amoeboid Motility J.Mol.Biol., 347, 2005
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3QWX
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![BU of 3qwx by Molmil](/molmil-images/mine/3qwx) | CED-2 1-174 | Descriptor: | Cell death abnormality protein 2, SULFATE ION | Authors: | Kang, Y, Sun, J, Liu, Y. | Deposit date: | 2011-02-28 | Release date: | 2011-06-08 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Crystal structure of the cell corpse engulfment protein CED-2 in Caenorhabditis elegans. Biochem.Biophys.Res.Commun., 410, 2011
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1LVK
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![BU of 1lvk by Molmil](/molmil-images/mine/1lvk) | X-RAY CRYSTAL STRUCTURE OF THE MG (DOT) 2'(3')-O-(N-METHYLANTHRANILOYL) NUCLEOTIDE BOUND TO DICTYOSTELIUM DISCOIDEUM MYOSIN MOTOR DOMAIN | Descriptor: | 2'(3')-O-N-METHYLANTHRANILOYL-ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | Authors: | Bauer, C.B, Kuhlman, P.A, Bagshaw, C.R, Rayment, I. | Deposit date: | 1997-09-05 | Release date: | 1998-01-28 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | X-ray crystal structure and solution fluorescence characterization of Mg.2'(3')-O-(N-methylanthraniloyl) nucleotides bound to the Dictyostelium discoideum myosin motor domain. J.Mol.Biol., 274, 1997
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1WYP
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![BU of 1wyp by Molmil](/molmil-images/mine/1wyp) | Solution structure of the CH domain of human Calponin 1 | Descriptor: | Calponin 1 | Authors: | Tomizawa, T, Kigawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-02-15 | Release date: | 2005-08-15 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the CH domain of human Calponin 1 To be Published
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1KZ7
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![BU of 1kz7 by Molmil](/molmil-images/mine/1kz7) | Crystal Structure of the DH/PH Fragment of Murine Dbs in Complex with the Placental Isoform of Human Cdc42 | Descriptor: | CDC42 HOMOLOG, GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS | Authors: | Rossman, K.L, Worthylake, D.K, Snyder, J.T, Siderovski, D.P, Campbell, S.L, Sondek, J. | Deposit date: | 2002-02-06 | Release date: | 2002-03-20 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange. EMBO J., 21, 2002
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7SCS
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![BU of 7scs by Molmil](/molmil-images/mine/7scs) | Crystal Structure of the Tick Evasin EVA-AAM1001 Complexed to Human Chemokine CCL11 | Descriptor: | Eotaxin, Evasin P1243 | Authors: | Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J. | Deposit date: | 2021-09-29 | Release date: | 2023-03-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins. Nat Commun, 14, 2023
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1MND
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![BU of 1mnd by Molmil](/molmil-images/mine/1mnd) | |
3S28
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![BU of 3s28 by Molmil](/molmil-images/mine/3s28) | The crystal structure of sucrose synthase-1 in complex with a breakdown product of the UDP-glucose | Descriptor: | 1,5-anhydro-D-arabino-hex-1-enitol, 1,5-anhydro-D-fructose, MALONIC ACID, ... | Authors: | Zheng, Y, Garavito, R.M. | Deposit date: | 2011-05-16 | Release date: | 2011-08-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The Structure of Sucrose Synthase-1 from Arabidopsis thaliana and Its Functional Implications. J.Biol.Chem., 286, 2011
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1B4S
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![BU of 1b4s by Molmil](/molmil-images/mine/1b4s) | STRUCTURE OF NUCLEOSIDE DIPHOSPHATE KINASE H122G MUTANT | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NUCLEOSIDE DIPHOSPHATE KINASE, ... | Authors: | Meyer, P, Janin, J. | Deposit date: | 1998-12-28 | Release date: | 1999-06-15 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Nucleophilic activation by positioning in phosphoryl transfer catalyzed by nucleoside diphosphate kinase. Biochemistry, 38, 1999
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6V69
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![BU of 6v69 by Molmil](/molmil-images/mine/6v69) | Structures of GCP4 and GCP5 in the native human gamma-tubulin ring complex | Descriptor: | Gamma-tubulin complex component 4, Gamma-tubulin complex component 5 | Authors: | Wieczorek, M, Urnavicius, L, Ti, S, Molloy, K.R, Chait, B.T, Kapoor, T.M. | Deposit date: | 2019-12-04 | Release date: | 2020-01-01 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Asymmetric Molecular Architecture of the Human gamma-Tubulin Ring Complex. Cell, 180, 2020
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6V6C
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![BU of 6v6c by Molmil](/molmil-images/mine/6v6c) | Structure of GCP6 in the native human gamma-tubulin ring complex | Descriptor: | Gamma-tubulin complex component 6 | Authors: | Wieczorek, M, Urnavicius, L, Ti, S, Molloy, K.R, Chait, B.T, Kapoor, T.M. | Deposit date: | 2019-12-04 | Release date: | 2020-01-01 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Asymmetric Molecular Architecture of the Human gamma-Tubulin Ring Complex. Cell, 180, 2020
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6V5V
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![BU of 6v5v by Molmil](/molmil-images/mine/6v5v) | Structure of gamma-tubulin in the native human gamma-tubulin ring complex | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Tubulin gamma-1 chain | Authors: | Wieczorek, M, Urnavicius, L, Ti, S, Molloy, K.R, Chait, B.T, Kapoor, T.M. | Deposit date: | 2019-12-04 | Release date: | 2020-01-01 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Asymmetric Molecular Architecture of the Human gamma-Tubulin Ring Complex. Cell, 180, 2020
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6V6B
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![BU of 6v6b by Molmil](/molmil-images/mine/6v6b) | Structures of GCP2 and GCP3 in the native human gamma-tubulin ring complex | Descriptor: | Gamma-tubulin complex component 2, Gamma-tubulin complex component 3 | Authors: | Wieczorek, M, Urnavicius, L, Ti, S, Molloy, K.R, Chait, B.T, Kapoor, T.M. | Deposit date: | 2019-12-04 | Release date: | 2020-01-01 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Asymmetric Molecular Architecture of the Human gamma-Tubulin Ring Complex. Cell, 180, 2020
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1E0S
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![BU of 1e0s by Molmil](/molmil-images/mine/1e0s) | small G protein Arf6-GDP | Descriptor: | ADP-ribosylation factor 6, AMMONIUM ION, BETA-MERCAPTOETHANOL, ... | Authors: | Menetrey, J, Cherfils, J. | Deposit date: | 2000-04-06 | Release date: | 2000-04-18 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structure of Arf6-Gdp Suggests a Basis for Guanine Nucleotide Exchange Factors Specificity Nat.Struct.Biol., 7, 2000
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1EOT
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![BU of 1eot by Molmil](/molmil-images/mine/1eot) | |
1BUX
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![BU of 1bux by Molmil](/molmil-images/mine/1bux) | 3'-PHOSPHORYLATED NUCLEOTIDES BINDING TO NUCLEOSIDE DIPHOSPHATE KINASE | Descriptor: | 3'-PHOSPHATE-ADENOSINE-5'-PHOSPHATE SULFATE, NUCLEOSIDE DIPHOSPHATE KINASE | Authors: | Xu, Y, Schneider, B, Deville-Bonne, D, Veron, M, Janin, J. | Deposit date: | 1998-09-07 | Release date: | 1999-04-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | 3'-Phosphorylated nucleotides are tight binding inhibitors of nucleoside diphosphate kinase activity. J.Biol.Chem., 273, 1998
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1DG3
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![BU of 1dg3 by Molmil](/molmil-images/mine/1dg3) | STRUCTURE OF HUMAN GUANYLATE BINDING PROTEIN-1 IN NUCLEOTIDE FREE FORM | Descriptor: | PROTEIN (INTERFERON-INDUCED GUANYLATE-BINDING PROTEIN 1) | Authors: | Prakash, B, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C. | Deposit date: | 1999-11-23 | Release date: | 2000-10-11 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins. Nature, 403, 2000
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1CD9
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![BU of 1cd9 by Molmil](/molmil-images/mine/1cd9) | 2:2 COMPLEX OF G-CSF WITH ITS RECEPTOR | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (G-CSF RECEPTOR), PROTEIN (GRANULOCYTE COLONY-STIMULATING FACTOR) | Authors: | Aritomi, M, Kunishima, N, Okamoto, T, Kuroki, R, Ota, Y, Morikawa, K. | Deposit date: | 1999-03-08 | Release date: | 2000-03-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Atomic structure of the GCSF-receptor complex showing a new cytokine-receptor recognition scheme. Nature, 401, 1999
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1F3F
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![BU of 1f3f by Molmil](/molmil-images/mine/1f3f) | STRUCTURE OF THE H122G NUCLEOSIDE DIPHOSPHATE KINASE / D4T-TRIPHOSPHATE.MG COMPLEX | Descriptor: | 2',3'-DEHYDRO-2',3'-DEOXY-THYMIDINE 5'-DIPHOSPHATE, 2',3'-DEHYDRO-2',3'-DEOXY-THYMIDINE 5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Meyer, P, Schneider, B, Sarfati, S, Deville-Bonne, D, Guerreiro, C, Boretto, J, Janin, J, Veron, M, Canard, B. | Deposit date: | 2000-06-02 | Release date: | 2000-09-13 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis for activation of alpha-boranophosphate nucleotide analogues targeting drug-resistant reverse transcriptase. EMBO J., 19, 2000
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1F5N
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![BU of 1f5n by Molmil](/molmil-images/mine/1f5n) | HUMAN GUANYLATE BINDING PROTEIN-1 IN COMPLEX WITH THE GTP ANALOGUE, GMPPNP. | Descriptor: | INTERFERON-INDUCED GUANYLATE-BINDING PROTEIN 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | Authors: | Prakash, B, Renault, L, Praefcke, G.J.K, Herrmann, C, Wittinghofer, A. | Deposit date: | 2000-06-15 | Release date: | 2000-09-27 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Triphosphate structure of guanylate-binding protein 1 and implications for nucleotide binding and GTPase mechanism. EMBO J., 19, 2000
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1F6T
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![BU of 1f6t by Molmil](/molmil-images/mine/1f6t) | STRUCTURE OF THE NUCLEOSIDE DIPHOSPHATE KINASE/ALPHA-BORANO(RP)-TDP.MG COMPLEX | Descriptor: | 2*-DEOXY-THYMIDINE-5*-ALPHA BORANO DIPHOSPHATE (ISOMER RP), MAGNESIUM ION, PROTEIN (NUCLEOSIDE DIPHOSPHATE KINASE) | Authors: | Guerreiro, C, Boretto, J, Janin, J, Veron, M, Canard, B, Schneider, B, Sarfati, S, Deville-Bonne, D. | Deposit date: | 2000-06-23 | Release date: | 2000-09-13 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structural basis for activation of alpha-boranophosphate nucleotide analogues targeting drug-resistant reverse transcriptase. EMBO J., 19, 2000
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1B99
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![BU of 1b99 by Molmil](/molmil-images/mine/1b99) | 3'-FLUORO-URIDINE DIPHOSPHATE BINDING TO NUCLEOSIDE DIPHOSPHATE KINASE | Descriptor: | 2',3'-DIDEOXY-3'-FLUORO-URIDIDINE-5'-DIPHOSPHATE, PROTEIN (NUCLEOSIDE DIPHOSPHATE KINASE), PYROPHOSPHATE 2- | Authors: | Janin, J, Xu, Y. | Deposit date: | 1999-02-22 | Release date: | 1999-06-28 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Catalytic mechanism of nucleoside diphosphate kinase investigated using nucleotide analogues, viscosity effects, and X-ray crystallography. Biochemistry, 38, 1999
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