2G4B
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![BU of 2g4b by Molmil](/molmil-images/mine/2g4b) | Structure of U2AF65 variant with polyuridine tract | Descriptor: | 1,4-DIETHYLENE DIOXIDE, 5'-R(P*UP*UP*UP*UP*UP*UP*U)-3', Splicing factor U2AF 65 kDa subunit | Authors: | Sickmier, E.A, Kielkopf, C.L. | Deposit date: | 2006-02-21 | Release date: | 2006-07-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis of polypyrimidine tract recognition
by the essential splicing factor U2AF65. Mol.Cell, 23, 2006
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6DLB
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6QI3
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![BU of 6qi3 by Molmil](/molmil-images/mine/6qi3) | Time resolved structural analysis of the full turnover of an enzyme - 27072 ms | Descriptor: | Fluoroacetate dehalogenase, GLYCOLIC ACID | Authors: | Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D. | Deposit date: | 2019-01-17 | Release date: | 2019-09-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.739 Å) | Cite: | Time-resolved crystallography reveals allosteric communication aligned with molecular breathing. Science, 365, 2019
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6DCV
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![BU of 6dcv by Molmil](/molmil-images/mine/6dcv) | Crystal structure of human anti-tau antibody CBTAU-27.1 | Descriptor: | GLYCEROL, Light chain of CBTAU27.1 Fab, heavy chain of CBTAU-27.1 Fab | Authors: | Zhu, X, Zhang, H, Wilson, I.A. | Deposit date: | 2018-05-08 | Release date: | 2018-06-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities. Acta Neuropathol Commun, 6, 2018
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6QGY
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![BU of 6qgy by Molmil](/molmil-images/mine/6qgy) | Crystal structure of E.coli BamA beta-barrel in complex with nanobody B12 | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, NanoB12, Outer membrane protein assembly factor BamA | Authors: | Hartmann, J.-B, Kaur, H, Jakob, R.P, Zahn, M, Zimmermann, I, Seeger, M, Maier, T, Hiller, S. | Deposit date: | 2019-01-14 | Release date: | 2019-06-26 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.509 Å) | Cite: | Identification of conformation-selective nanobodies against the membrane protein insertase BamA by an integrated structural biology approach. J.Biomol.Nmr, 73, 2019
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4OZK
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4OZX
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6QIR
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![BU of 6qir by Molmil](/molmil-images/mine/6qir) | Crystal structure of CAG repeats with synthetic CMBL3a compound (model I) | Descriptor: | CMBL3a, RNA (5'-R(*GP*CP*AP*GP*CP*AP*GP*C)-3') | Authors: | Kiliszek, A, Blaszczyk, L, Rypniewski, W, Nakatani, K. | Deposit date: | 2019-01-21 | Release date: | 2019-09-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.531 Å) | Cite: | Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats. Nucleic Acids Res., 47, 2019
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4P09
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![BU of 4p09 by Molmil](/molmil-images/mine/4p09) | Crystal structure of HOIP PUB domain | Descriptor: | E3 ubiquitin-protein ligase RNF31 | Authors: | Akutsu, M, Schaeffer, V, Olma, M.H, Gomes, L.C, Kawasaki, M, Dikic, I. | Deposit date: | 2014-02-20 | Release date: | 2014-05-07 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Binding of OTULIN to the PUB domain of HOIP controls NF-kappa B signaling. Mol.Cell, 54, 2014
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6QIU
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![BU of 6qiu by Molmil](/molmil-images/mine/6qiu) | Crystal structure of 14-3-3 sigma in complex with Ataxin-1 Ser776 phosphopeptide | Descriptor: | 14-3-3 protein sigma, Ataxin-1 phosphopeptide, CHLORIDE ION, ... | Authors: | Leysen, S, Milroy, L.G, Davis, J.M, Brunsveld, L, Ottmann, C. | Deposit date: | 2019-01-21 | Release date: | 2020-05-13 | Method: | X-RAY DIFFRACTION (1.802 Å) | Cite: | Structural insights into the cytoplasmic chaperone effect of 14-3-3 proteins on Ataxin-1 To Be Published
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2G4G
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6QK7
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![BU of 6qk7 by Molmil](/molmil-images/mine/6qk7) | Elongator catalytic subcomplex Elp123 lobe | Descriptor: | 5'-DEOXYADENOSINE, Elongator complex protein 1, Elongator complex protein 2, ... | Authors: | Dauden, M.I, Jaciuk, M, Glatt, S. | Deposit date: | 2019-01-28 | Release date: | 2019-07-17 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Molecular basis of tRNA recognition by the Elongator complex. Sci Adv, 5, 2019
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6QHV
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![BU of 6qhv by Molmil](/molmil-images/mine/6qhv) | Time resolved structural analysis of the full turnover of an enzyme - 100 ms | Descriptor: | Fluoroacetate dehalogenase, fluoroacetic acid | Authors: | Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D. | Deposit date: | 2019-01-17 | Release date: | 2019-09-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.715 Å) | Cite: | Time-resolved crystallography reveals allosteric communication aligned with molecular breathing. Science, 365, 2019
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3UDD
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![BU of 3udd by Molmil](/molmil-images/mine/3udd) | Tankyrase-1 in complex with small molecule inhibitor | Descriptor: | 3-(4-methoxyphenyl)-5-({[4-(4-methoxyphenyl)-5-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}methyl)-1,2,4-oxadiazole, GLYCEROL, SULFATE ION, ... | Authors: | Kirby, C.A, Stams, T. | Deposit date: | 2011-10-28 | Release date: | 2012-02-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | [1,2,4]triazol-3-ylsulfanylmethyl)-3-phenyl-[1,2,4]oxadiazoles: antagonists of the Wnt pathway that inhibit tankyrases 1 and 2 via novel adenosine pocket binding. J.Med.Chem., 55, 2012
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6DGD
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![BU of 6dgd by Molmil](/molmil-images/mine/6dgd) | PriA helicase bound to dsDNA of a DNA replication fork | Descriptor: | DNA (5'-D(P*AP*GP*CP*AP*CP*GP*CP*CP*GP*AP*CP*T)-3'), DNA (5'-D(P*GP*AP*GP*CP*AP*CP*GP*CP*CP*GP*AP*CP*T)-3'), DNA (5'-D(P*GP*TP*CP*GP*GP*CP*GP*TP*GP*CP*TP*C)-3'), ... | Authors: | Satyshur, K.A, Windgassen, T.A, Keck, J.L. | Deposit date: | 2018-05-17 | Release date: | 2018-09-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.823 Å) | Cite: | Structure-specific DNA replication-fork recognition directs helicase and replication restart activities of the PriA helicase. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6QK6
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6QKD
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![BU of 6qkd by Molmil](/molmil-images/mine/6qkd) | CRYSTAL STRUCTURE OF vhh-based FAB-fragment of antibody BCD-085 | Descriptor: | CHLORIDE ION, FAB HEAVY CHAIN, FAB LIGHT CHAIN, ... | Authors: | Kostareva, O.S, Kolyadenko, I.A, Ulitin, A.B, Ekimova, V.M, Evdokimov, S.R, Garber, M.B, Tishchenko, T.V, Gabdulkhakov, A.G. | Deposit date: | 2019-01-29 | Release date: | 2019-07-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Fab Fragment of VHH-Based Antibody Netakimab: Crystal Structure and Modeling Interaction with Cytokine IL-17A Crystals, 2019
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6DSV
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![BU of 6dsv by Molmil](/molmil-images/mine/6dsv) | Bst DNA polymerase I post-chemistry (n+2) structure | Descriptor: | DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(P*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ... | Authors: | Chim, N, Jackson, L.N, Chaput, J.C. | Deposit date: | 2018-06-14 | Release date: | 2018-10-31 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway. Elife, 7, 2018
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6QKS
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![BU of 6qks by Molmil](/molmil-images/mine/6qks) | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Tyr219Phe - Apo | Descriptor: | CHLORIDE ION, Fluoroacetate dehalogenase | Authors: | Mehrabi, P, Kim, T.H, Prosser, R.S, Pai, E.F. | Deposit date: | 2019-01-30 | Release date: | 2019-06-26 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Substrate-Based Allosteric Regulation of a Homodimeric Enzyme. J.Am.Chem.Soc., 141, 2019
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2G8I
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2G8W
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6DJQ
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![BU of 6djq by Molmil](/molmil-images/mine/6djq) | Vps1 GTPase-BSE fusion complexed with GDP.AlF4- | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, SODIUM ION, ... | Authors: | Varlakhanova, N.V, Brady, T.M, Tornabene, B.A, Hosford, C.J, Chappie, J.S, Ford, M.G.J. | Deposit date: | 2018-05-25 | Release date: | 2018-08-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structures of the fungal dynamin-related protein Vps1 reveal a unique, open helical architecture. J. Cell Biol., 217, 2018
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6PVT
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![BU of 6pvt by Molmil](/molmil-images/mine/6pvt) | Influenza B M2 Proton Channel in the Open State - SSNMR Structure at pH 4.5 | Descriptor: | BM2 protein | Authors: | Mandala, V.S, Loftis, A.R, Shcherbakov, A.S, Pentelute, B.L, Hong, M. | Deposit date: | 2019-07-21 | Release date: | 2020-02-05 | Last modified: | 2024-05-15 | Method: | SOLID-STATE NMR | Cite: | Atomic structures of closed and open influenza B M2 proton channel reveal the conduction mechanism. Nat.Struct.Mol.Biol., 27, 2020
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6DLA
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6QB1
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![BU of 6qb1 by Molmil](/molmil-images/mine/6qb1) | 5676 | Descriptor: | LEU-GLY-GLN-GLN-GLN-PRO-ALA-PRO-PRO-GLN-GLN-PRO-TYR | Authors: | Calvanese, L, D'Auria, G, Falcigno, F. | Deposit date: | 2018-12-20 | Release date: | 2019-02-27 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Structural insights on P31-43, a gliadin peptide able to promote an innate but not an adaptive response in celiac disease. J.Pept.Sci., 25, 2019
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