9G3T

Structure of the PRO-PRO endopeptidase (PPEP-3) E153A Y189F from Geobacillus thermodenitrificans

Summary for 9G3T

• Entry DOI: 10.2210/pdb9g3t/pdb
• Related: 9G0J
• Descriptor: ATLF-like domain-containing protein, ZINC ION, BICINE, ... (6 entities in total)
• Functional Keywords: endopeptidase, metalloprotease, zinc, hydrolase
• Biological source: Geobacillus thermodenitrificans NG80-2
• Total number of polymer chains: 2
• Total formula weight: 53584.70

Authors

Claushuis, B.,Wojtalla, F.,van Leeuwen, H.,Corver, J.,Baumann, U.,Hensbergen, P. (deposition date: 2024-07-12, release date: 2025-07-23, Last modification date: 2026-02-04)

• Primary citation: Claushuis, B.,Wojtalla, F.,Papenhagen, L.,Cordfunke, R.A.,de Ru, A.H.,van Leeuwen, H.C.,Corver, J.,Hensbergen, P.J.,Baumann, U.; Structural analyses and substrate profiling of PPEP-3 provide new insights into the molecular basis of Pro-Pro endopeptidase specificity; Iscience, 29:114360-, 2026; DOI: 10.1016/j.isci.2025.114360

Experimental method

X-RAY DIFFRACTION (1.6 Å)