PDB: 2286 resultsInfo pagesStatus searchChemie searchBIRD

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4QB3	Crystal structure of the first bromodomain of human BRD4 in complex with Olinone Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, N-[4-(1-oxo-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)butyl]acetamide Authors: Plotnikov, A.N, Joshua, J, Zhou, M.-M. Deposit date: 2014-05-06 Release date: 2015-04-22 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (0.94 Å) Cite: Selective chemical modulation of gene transcription favors oligodendrocyte lineage progression. Chem.Biol., 21, 2014
7FH2	Crystal structure of the first bromodomain of BRD4 in complex with 16D10 Descriptor: Bromodomain-containing protein 4, CHLORIDE ION, N-[2-[2-[(E)-3-(2,5-dimethoxyphenyl)prop-2-enoyl]-4,5-dimethoxy-phenyl]ethyl]ethanamide Authors: Yokoyama, T, Hirasawa, N. Deposit date: 2021-07-29 Release date: 2022-08-03 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.492 Å) Cite: A chalcone derivative suppresses TSLP induction in mice and human keratinocytes through binding to BET family proteins. Biochem Pharmacol, 194, 2021
4QYL	Crystal Structure of the human BRPF1 bromodomain in complex with a histone H2AK5ac peptide Descriptor: Histone H2A type 1, Peregrin, SULFATE ION Authors: Lubula, M.Y, Glass, K.C. Deposit date: 2014-07-24 Release date: 2014-09-24 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural insights into recognition of acetylated histone ligands by the BRPF1 bromodomain. Febs Lett., 588, 2014
4QYD	Crystal Structure of the human BRPF1 bromodomain in complex with a histone H4K12ac peptide Descriptor: Histone H4, Peregrin Authors: Lubula, M.Y, Glass, K.C. Deposit date: 2014-07-24 Release date: 2014-09-24 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.94 Å) Cite: Structural insights into recognition of acetylated histone ligands by the BRPF1 bromodomain. Febs Lett., 588, 2014
7FV1	PanDDA analysis group deposition -- PHIP in complex with Z4912742920 Descriptor: PH-interacting protein, tert-butyl [3-({[4-(furan-2-carbonyl)piperazine-1-carbonyl]amino}methyl)phenyl]carbamate Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.19 Å) Cite: PanDDA analysis group deposition To Be Published
7FVG	PanDDA analysis group deposition -- PHIP in complex with Z992453336 Descriptor: N-(4-methoxyphenyl)-4-(5-methylfuran-2-carbonyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.15 Å) Cite: PanDDA analysis group deposition To Be Published
7FVL	PanDDA analysis group deposition -- PHIP in complex with Z4140355932 Descriptor: N-{[(2S)-5,5-dimethyl-1,4-dioxan-2-yl]methyl}-4-(3-hydroxybenzoyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.15 Å) Cite: PanDDA analysis group deposition To Be Published
7FV2	PanDDA analysis group deposition -- PHIP in complex with Z445899798 Descriptor: N-(2-methoxyethyl)-4-(thiophene-2-carbonyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.15 Å) Cite: PanDDA analysis group deposition To Be Published
7FUT	PanDDA analysis group deposition -- PHIP in complex with Z44602357 Descriptor: 4-(furan-2-carbonyl)-N-propylpiperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.18 Å) Cite: PanDDA analysis group deposition To Be Published
7FUV	PanDDA analysis group deposition -- PHIP in complex with Z183376720 Descriptor: N-cyclopropyl-4-(furan-2-carbonyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.19 Å) Cite: PanDDA analysis group deposition To Be Published
7FVI	PanDDA analysis group deposition -- PHIP in complex with Z183306756 Descriptor: N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-(furan-2-carbonyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.18 Å) Cite: PanDDA analysis group deposition To Be Published
7FVJ	PanDDA analysis group deposition -- PHIP in complex with Z4913873236 Descriptor: (2S)-4-(furan-2-carbonyl)-2-methyl-N-(2,2,2-trifluoroethyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.19 Å) Cite: PanDDA analysis group deposition To Be Published
7FV9	PanDDA analysis group deposition -- PHIP in complex with Z1004253138 Descriptor: 4-(5-methylfuran-2-carbonyl)-N-[(thiophen-2-yl)methyl]piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.17 Å) Cite: PanDDA analysis group deposition To Be Published
7FVM	PanDDA analysis group deposition -- PHIP in complex with Z1590917771 Descriptor: 4-(furan-2-carbonyl)-N-(1,2-oxazol-3-yl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.26 Å) Cite: PanDDA analysis group deposition To Be Published
7FUW	PanDDA analysis group deposition -- PHIP in complex with Z961579360 Descriptor: (3S)-2-benzyl-N'-[4-(furan-2-carbonyl)piperazine-1-carbonyl]-1,2,3,4-tetrahydroisoquinoline-3-carbohydrazide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.19 Å) Cite: PanDDA analysis group deposition To Be Published
7FUX	PanDDA analysis group deposition -- PHIP in complex with Z183480798 Descriptor: 4-(furan-2-carbonyl)-N-(prop-2-yn-1-yl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.22 Å) Cite: PanDDA analysis group deposition To Be Published
7FUY	PanDDA analysis group deposition -- PHIP in complex with Z1284554279 Descriptor: N-[2-(3-ethyl-4H-1,2,4-triazol-4-yl)ethyl]-4-(5-methylthiophene-2-carbonyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.15 Å) Cite: PanDDA analysis group deposition To Be Published
7FV4	PanDDA analysis group deposition -- PHIP in complex with Z44602341 Descriptor: N-(2-fluorophenyl)-4-(furan-2-carbonyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.15 Å) Cite: PanDDA analysis group deposition To Be Published
7FVP	PanDDA analysis group deposition -- PHIP in complex with Z1004277578 Descriptor: N-butyl-4-(5-methylfuran-2-carbonyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.15 Å) Cite: PanDDA analysis group deposition To Be Published
7FVA	PanDDA analysis group deposition -- PHIP in complex with Z4913872963 Descriptor: (2S)-N-(cyclopropylmethyl)-4-(furan-2-carbonyl)-2-methylpiperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.19 Å) Cite: PanDDA analysis group deposition To Be Published
7FVQ	PanDDA analysis group deposition -- PHIP in complex with Z68576046 Descriptor: N-butyl-4-(thiophene-2-carbonyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.15 Å) Cite: PanDDA analysis group deposition To Be Published
7FVC	PanDDA analysis group deposition -- PHIP in complex with Z495704106 Descriptor: N-(cyclopropylmethyl)-4-(3,4-dichlorobenzoyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.18 Å) Cite: PanDDA analysis group deposition To Be Published
7FV3	PanDDA analysis group deposition -- PHIP in complex with Z4912742924 Descriptor: (2R)-N-butyl-4-(furan-2-carbonyl)-2-methylpiperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.15 Å) Cite: PanDDA analysis group deposition To Be Published
7FV5	PanDDA analysis group deposition -- PHIP in complex with Z606695272 Descriptor: 4-(furan-2-carbonyl)-N-(pyridin-2-yl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.15 Å) Cite: PanDDA analysis group deposition To Be Published
7FV6	PanDDA analysis group deposition -- PHIP in complex with Z1334218055 Descriptor: N-methyl-4-[5-(phenoxymethyl)furan-2-carbonyl]piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.19 Å) Cite: PanDDA analysis group deposition To Be Published

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