8YHV
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8YHP
| Structure of the PGK1 from Biortus. | Descriptor: | 1,2-ETHANEDIOL, Phosphoglycerate kinase 1 | Authors: | Wang, F, Cheng, W, Lv, Z, Ju, C, Wang, J. | Deposit date: | 2024-02-28 | Release date: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure of the PGK1 from Biortus. To Be Published
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8YHE
| Cryo-EM structure of CTR-bound type VII CRISPR-Cas complex at post-state II | Descriptor: | RNA (29-MER), RNA (46-MER), ZINC ION, ... | Authors: | Zhang, H, Deng, Z, Li, X. | Deposit date: | 2024-02-28 | Release date: | 2024-08-21 | Last modified: | 2024-09-25 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Structural basis for the activity of the type VII CRISPR-Cas system. Nature, 633, 2024
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8YHD
| Cryo-EM structure of CTR-bound type VII CRISPR-Cas complex at post-state I | Descriptor: | RNA (35-MER), RNA (53-MER), ZINC ION, ... | Authors: | Zhang, H, Deng, Z, Li, X. | Deposit date: | 2024-02-28 | Release date: | 2024-08-21 | Last modified: | 2024-09-25 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | Structural basis for the activity of the type VII CRISPR-Cas system. Nature, 633, 2024
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9AUC
| Human Amylin1 Receptor in Complex with Gs and human Calcitonin Gene-Related Peptide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Calcitonin gene-related peptide 1, ... | Authors: | Cao, J, Belousoff, M.J, Wootten, D.L, Sexton, P.M. | Deposit date: | 2024-02-28 | Release date: | 2024-04-24 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Cryo-EM Structure of the Human Amylin 1 Receptor in Complex with CGRP and Gs Protein. Biochemistry, 63, 2024
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9ATK
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9ATU
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8YHA
| Type I-EHNH Cascade-ssDNA complex | Descriptor: | 61-nt crRNA, CRISPR system Cascade subunit CasC, CRISPR system Cascade subunit CasD, ... | Authors: | Li, Z. | Deposit date: | 2024-02-27 | Release date: | 2024-07-31 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Mechanisms for HNH-mediated target DNA cleavage in type I CRISPR-Cas systems. Mol.Cell, 84, 2024
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8YH9
| Type I-FHNH Cascade complex | Descriptor: | 60-nt crRNA, Cas5f, Cas6f, ... | Authors: | Li, Z. | Deposit date: | 2024-02-27 | Release date: | 2024-07-31 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Mechanisms for HNH-mediated target DNA cleavage in type I CRISPR-Cas systems. Mol.Cell, 84, 2024
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9ASO
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9ASX
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9ASQ
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9ASM
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9ASN
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9ASS
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9ASP
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8YGJ
| SpCas9-MMLV RT-pegRNA-target DNA complex (elongation 28-nt) | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(P*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), DNA (51-MER), ... | Authors: | Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O. | Deposit date: | 2024-02-26 | Release date: | 2024-06-05 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis for pegRNA-guided reverse transcription by a prime editor. Nature, 631, 2024
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9ASI
| Cryo-EM structure of the active Lactococcus lactis Csm bound to target in pre-cleavage stage | Descriptor: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CRISPR RNA, ... | Authors: | Wang, B, Goswami, H.N, Li, H. | Deposit date: | 2024-02-25 | Release date: | 2024-08-14 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (2.79 Å) | Cite: | Molecular basis for cA6 synthesis by a type III-A CRISPR-Cas enzyme and its conversion to cA4 production. Nucleic Acids Res., 52, 2024
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9ASH
| Cryo-EM structure of the active Lactococcus lactis Csm bound to target in post-cleavage stage | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CRISPR RNA, CRISPR system Cms endoribonuclease Csm3, ... | Authors: | Wang, B, Goswami, H.N, Li, H. | Deposit date: | 2024-02-25 | Release date: | 2024-08-14 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (2.58 Å) | Cite: | Molecular basis for cA6 synthesis by a type III-A CRISPR-Cas enzyme and its conversion to cA4 production. Nucleic Acids Res., 52, 2024
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8YFR
| Cryo EM structure of Komagataella phaffii Rat1-Rai1 complex bound within the RNAPII cleft | Descriptor: | 5'-3' exoribonuclease, DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | Authors: | Murayama, Y, Yanagisawa, T, Ehara, H, Sekine, S. | Deposit date: | 2024-02-25 | Release date: | 2024-09-25 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis of eukaryotic transcription termination by the Rat1 exonuclease complex. Nat Commun, 15, 2024
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8YFQ
| Cryo EM structure of Komagataella phaffii RNAPII-Rat1-Rai1 pre-termination complex | Descriptor: | 5'-3' exoribonuclease, DNA (90-mer), DNA-directed RNA polymerase subunit, ... | Authors: | Murayama, Y, Yanagisawa, T, Ehara, H, Sekine, S. | Deposit date: | 2024-02-25 | Release date: | 2024-09-25 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis of eukaryotic transcription termination by the Rat1 exonuclease complex. Nat Commun, 15, 2024
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8S5N
| RNA polymerase II core initially transcribing complex with an ordered RNA of 12 nt | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. | Deposit date: | 2024-02-24 | Release date: | 2024-04-10 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Three-step mechanism of promoter escape by RNA polymerase II. Mol.Cell, 84, 2024
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8YF5
| Cryo EM structure of Komagataella phaffii Rat1-Rai1-Rtt103 complex | Descriptor: | 5'-3' exoribonuclease, Decapping nuclease, Exonuclease Rat1p and Rai1p interacting protein | Authors: | Yanagisawa, T, Murayama, Y, Ehara, H, Sekine, S.I. | Deposit date: | 2024-02-24 | Release date: | 2024-09-25 | Method: | ELECTRON MICROSCOPY (3.78 Å) | Cite: | Structural basis of eukaryotic transcription termination by the Rat1 exonuclease complex. Nat Commun, 15, 2024
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8YFE
| Cryo EM structure of Komagataella phaffii Rat1-Rai1 complex | Descriptor: | 5'-3' exoribonuclease, Decapping nuclease | Authors: | Yanagisawa, T, Murayama, Y, Ehara, H, Sekine, S.I. | Deposit date: | 2024-02-24 | Release date: | 2024-09-25 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Structural basis of eukaryotic transcription termination by the Rat1 exonuclease complex. Nat Commun, 15, 2024
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8S5F
| Crystal structure of the HExxH domain of ChlBHExxH a novel alpha-ketoglutarate dependent oxygenase | Descriptor: | ChlH from Chlorogloeopsis sp., PHOSPHATE ION | Authors: | de la Mora, E, Amara, P, Usclat, A, Morishita, Y, Morinaka, B, Nicolet, Y. | Deposit date: | 2024-02-23 | Release date: | 2024-10-02 | Method: | X-RAY DIFFRACTION (2.797 Å) | Cite: | Fused radical SAM and alpha KG-HExxH domain proteins contain a distinct structural fold and catalyse cyclophane formation and beta-hydroxylation. Nat.Chem., 2024
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