9ASH
Cryo-EM structure of the active Lactococcus lactis Csm bound to target in post-cleavage stage
Summary for 9ASH
Entry DOI | 10.2210/pdb9ash/pdb |
EMDB information | 43814 |
Descriptor | CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), MAGNESIUM ION, CRISPR-associated protein Csm4, ... (11 entities in total) |
Functional Keywords | type iii-a crispr-cas, csm, cyclic oligoadenylate synthesis, rna binding protein-rna complex, rna binding protein/rna |
Biological source | Lactococcus lactis subsp. lactis More |
Total number of polymer chains | 13 |
Total formula weight | 333638.46 |
Authors | |
Primary citation | Goswami, H.N.,Ahmadizadeh, F.,Wang, B.,Addo-Yobo, D.,Zhao, Y.,Whittington, A.C.,He, H.,Terns, M.P.,Li, H. Molecular basis for cA6 synthesis by a type III-A CRISPR-Cas enzyme and its conversion to cA4 production. Nucleic Acids Res., 2024 Cited by PubMed: 38989619DOI: 10.1093/nar/gkae603 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.58 Å) |
Structure validation
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