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2ZKF
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BU of 2zkf by Molmil
Crystal structure of the SRA domain of mouse Np95 in complex with hemi-methylated CpG DNA
Descriptor: DNA (5'-D(*DCP*DTP*DAP*DTP*DCP*(5CM)P*DGP*DGP*DTP*DGP*DA)-3'), DNA (5'-D(P*DCP*DAP*DCP*DCP*DGP*DGP*DAP*DTP*DAP*DGP*DA)-3'), E3 ubiquitin-protein ligase UHRF1
Authors:Arita, K, Ariyoshi, M, Tochio, H, Nakamura, Y, Shirakawa, M.
Deposit date:2008-03-19
Release date:2008-09-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism
Nature, 455, 2008
5WFY
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BU of 5wfy by Molmil
Crystal structure of DNA-binding domain of the bacteriophage T4 ligase
Descriptor: DNA ligase, GLYCEROL
Authors:Shi, K, Aihara, H.
Deposit date:2017-07-13
Release date:2018-09-26
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:T4 DNA ligase structure reveals a prototypical ATP-dependent ligase with a unique mode of sliding clamp interaction.
Nucleic Acids Res., 46, 2018
3W1O
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BU of 3w1o by Molmil
Neisseria DNA mimic protein DMP12
Descriptor: DNA mimic protein DMP12, MAGNESIUM ION
Authors:Wang, H.C, Ko, T.P, Wu, M.L, Wang, A.H.J.
Deposit date:2012-11-19
Release date:2013-04-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Neisseria conserved hypothetical protein DMP12 is a DNA mimic that binds to histone-like HU protein
Nucleic Acids Res., 41, 2013
3RHI
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BU of 3rhi by Molmil
DNA-binding protein HU from Bacillus anthracis
Descriptor: DNA-binding protein HU
Authors:Osipiuk, J, Makowska-Grzyska, M, Hasseman, J, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-04-11
Release date:2011-04-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:DNA-binding protein HU from Bacillus anthracis.
To be Published
5NWA
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BU of 5nwa by Molmil
Crystal structure of the complex of Tdp1 with duplex DNA
Descriptor: DNA (5'-D(P*AP*AP*TP*GP*CP*GP*CP*AP*TP*TP*A)-3'), Tyrosyl-DNA phosphodiesterase 1
Authors:Richardson, J.M, Ruksenaite, E, Morris, E.R.
Deposit date:2017-05-05
Release date:2018-01-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for DNA 3'-end processing by human tyrosyl-DNA phosphodiesterase 1.
Nat Commun, 9, 2018
5NW9
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BU of 5nw9 by Molmil
Crystal structure of the complex of Tdp1 with duplex DNA
Descriptor: DNA (5'-D(P*TP*GP*CP*GP*CP*AP*GP*TP*A)-3'), Tyrosyl-DNA phosphodiesterase 1
Authors:Richardson, J.M, Ruksenaite, E, Morris, E.R.
Deposit date:2017-05-05
Release date:2018-01-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural basis for DNA 3'-end processing by human tyrosyl-DNA phosphodiesterase 1.
Nat Commun, 9, 2018
1BNP
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BU of 1bnp by Molmil
NMR SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF DNA POLYMERASE BETA, 55 STRUCTURES
Descriptor: DNA POLYMERASE BETA
Authors:Liu, D.-J, Prasad, R, Wilson, S.H, Derose, E.F, Mullen, G.P.
Deposit date:1996-04-25
Release date:1996-12-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of the N-terminal domain of DNA polymerase beta and mapping of the ssDNA interaction interface.
Biochemistry, 35, 1996
1BNO
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BU of 1bno by Molmil
NMR SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF DNA POLYMERASE BETA, MINIMIZED AVERAGE STRUCTURE
Descriptor: DNA POLYMERASE BETA
Authors:Liu, D.-J, Prasad, R, Wilson, S.H, Derose, E.F, Mullen, G.P.
Deposit date:1996-04-25
Release date:1996-12-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of the N-terminal domain of DNA polymerase beta and mapping of the ssDNA interaction interface.
Biochemistry, 35, 1996
1JN3
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BU of 1jn3 by Molmil
FIDELITY PROPERTIES AND STRUCTURE OF M282L MUTATOR MUTANT OF DNA POLYMERASE: SUBTLE STRUCTURAL CHANGES INFLUENCE THE MECHANISM OF NUCLEOTIDE DISCRIMINATION
Descriptor: DNA POLYMERASE BETA
Authors:Conn, D.A, Sweasy, J.B, Jaeger, J.
Deposit date:2001-07-22
Release date:2001-08-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:A DNA polymerase beta mutator mutant with reduced nucleotide discrimination and increased protein stability
Biochemistry, 40, 2001
6FWS
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BU of 6fws by Molmil
Structure of DinG in complex with ssDNA and ADPBeF
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase DinG, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Cheng, K, Wigley, D.
Deposit date:2018-03-07
Release date:2018-12-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:DNA translocation mechanism of an XPD family helicase.
Elife, 7, 2018
4M9V
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BU of 4m9v by Molmil
Zfp57 mutant (E182Q) in complex with 5-carboxylcytosine DNA
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ...
Authors:Liu, Y, Olanrewaju, Y.O, Zhang, X, Cheng, X.
Deposit date:2013-08-15
Release date:2013-11-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (0.969 Å)
Cite:DNA recognition of 5-carboxylcytosine by a zfp57 mutant at an atomic resolution of 0.97 angstrom.
Biochemistry, 52, 2013
6FWR
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BU of 6fwr by Molmil
Structure of DinG in complex with ssDNA
Descriptor: ATP-dependent DNA helicase DinG, DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), IRON/SULFUR CLUSTER
Authors:Cheng, K, Wigley, D.B.
Deposit date:2018-03-07
Release date:2018-12-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:DNA translocation mechanism of an XPD family helicase.
Elife, 7, 2018
6MII
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BU of 6mii by Molmil
Crystal structure of minichromosome maintenance protein MCM/DNA complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ...
Authors:Enemark, E.J, Meagher, M, Epling, L.B.
Deposit date:2018-09-19
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:DNA translocation mechanism of the MCM complex and implications for replication initiation.
Nat Commun, 10, 2019
8XIC
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BU of 8xic by Molmil
Structure of Trioxacarcin A covalently bound to guanosine-2'-fluorinated d(AACCGGTT)2
Descriptor: DNA (5'-D(*AP*AP*CP*CP*2''F-GP*2''F-GP*TP*T)-3'), Trioxacarcin A, bound form
Authors:Gao, R.Q, Cao, C, Tang, G.L.
Deposit date:2023-12-19
Release date:2024-12-04
Last modified:2024-12-11
Method:SOLUTION NMR
Cite:Different DNA Binding and Damage Mode between Anticancer Antibiotics Trioxacarcin A and LL-D49194 alpha 1.
Jacs Au, 4, 2024
5A9J
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BU of 5a9j by Molmil
Crystal structure of the Helicase domain of human DNA polymerase theta, apo-form
Descriptor: DNA POLYMERASE THETA
Authors:Newman, J.A, Cooper, C.D.O, Aitkenhead, H, Pinkas, D.M, Kupinska, K, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
Deposit date:2015-07-21
Release date:2015-12-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway.
Structure, 23, 2015
8VPI
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BU of 8vpi by Molmil
CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA and Containing Quinoline-based SGI-1027 Analog 462
Descriptor: DNA Strand I, DNA Strand II, N-{3-[(2-amino-6-methylpyrimidin-4-yl)amino]-5-[(4-methylpiperazin-1-yl)methyl]phenyl}-3-[(quinolin-4-yl)amino]benzamide, ...
Authors:Zhou, J, Horton, J.R, Cheng, X.
Deposit date:2024-01-16
Release date:2024-09-25
Last modified:2024-10-02
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Quinoline-based compounds can inhibit diverse enzymes that act on DNA.
Biorxiv, 2024
8VPG
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BU of 8vpg by Molmil
CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA and Containing Quinoline-based SGI-1027 Analog 455
Descriptor: DNA Strand I, DNA Strand II, N-{3-[(2-amino-6-methylpyrimidin-4-yl)amino]-5-[(dimethylamino)methyl]phenyl}-3-[(quinolin-4-yl)amino]benzamide, ...
Authors:Zhou, J, Horton, J.R, Cheng, X.
Deposit date:2024-01-16
Release date:2024-09-25
Last modified:2024-10-02
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Quinoline-based compounds can inhibit diverse enzymes that act on DNA.
Biorxiv, 2024
8VPH
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BU of 8vph by Molmil
CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA and Containing Quinoline-based SGI-1027 Analog 455 and Inhibitor MC4741
Descriptor: DNA Strand I, DNA Strand II, N-(3-phenylpropyl)adenosine, ...
Authors:Zhou, J, Horton, J.R, Cheng, X.
Deposit date:2024-01-16
Release date:2024-09-25
Last modified:2024-10-02
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:Quinoline-based compounds can inhibit diverse enzymes that act on DNA.
Biorxiv, 2024
8Z79
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BU of 8z79 by Molmil
Crystal structure of 5-N-alpha-glycinylthymidine (N-alpha-GlyT) FAD-dependent lyase gp47/NGTO from Pseudomonas phage PaMx11 in complex with dsDNA
Descriptor: DNA (5'-D(*TP*AP*GP*TP*CP*AP*TP*GP*AP*CP*T)-3'), FLAVIN-ADENINE DINUCLEOTIDE, Flavin-dependent lyase
Authors:Wen, Y, Guo, W.T, Wu, B.X.
Deposit date:2024-04-19
Release date:2024-10-02
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural insights into the biosynthetic mechanism of N alpha-GlyT and 5-NmdU hypermodifications of DNA.
Nucleic Acids Res., 52, 2024
5JGH
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BU of 5jgh by Molmil
Crystal structure of the mitochondrial DNA packaging protein Abf2p in complex with DNA at 2.6 Angstrom resolution
Descriptor: ACETATE ION, ARS-binding factor 2, mitochondrial, ...
Authors:Chakraborty, A, Lyonnais, S, Sola, M.
Deposit date:2016-04-20
Release date:2017-02-08
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:DNA structure directs positioning of the mitochondrial genome packaging protein Abf2p.
Nucleic Acids Res., 45, 2017
8Y1I
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BU of 8y1i by Molmil
Structure of guanosine-2''-fluorinated [d(AACCGGTT)]2
Descriptor: DNA (5'-D(*(3D1)P*AP*CP*CP*(GF2)P*(GF2)P*TP*T)-3')
Authors:Gao, R.Q, Cao, C, Tang, G.L.
Deposit date:2024-01-24
Release date:2024-12-04
Last modified:2024-12-11
Method:SOLUTION NMR
Cite:Different DNA Binding and Damage Mode between Anticancer Antibiotics Trioxacarcin A and LL-D49194 alpha 1.
Jacs Au, 4, 2024
5JH0
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BU of 5jh0 by Molmil
Crystal structure of the mitochondrial DNA packaging protein Abf2p in complex with DNA at 2.18 Angstrom resolution
Descriptor: ARS-binding factor 2, mitochondrial, DNA (5'-D(*AP*AP*TP*AP*AP*TP*AP*AP*AP*TP*TP*AP*TP*AP*TP*AP*AP*TP*AP*TP*AP*A)-3'), ...
Authors:Chakraborty, A, Lyonnais, S, Sola, M.
Deposit date:2016-04-20
Release date:2017-02-08
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:DNA structure directs positioning of the mitochondrial genome packaging protein Abf2p.
Nucleic Acids Res., 45, 2017
8VDS
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BU of 8vds by Molmil
DNA Ligase 1 with nick DNA 3'rG:C
Descriptor: DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*CP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA ligase 1, DNA/RNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-R(P*G)-D(P*GP*TP*CP*GP*GP*AP*C)-3')
Authors:KanalElamparithi, B, Gulkis, M, Caglayan, M.
Deposit date:2023-12-17
Release date:2024-05-22
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structures of LIG1 provide a mechanistic basis for understanding a lack of sugar discrimination against a ribonucleotide at the 3'-end of nick DNA.
J.Biol.Chem., 300, 2024
8VDT
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BU of 8vdt by Molmil
DNA Ligase 1 with nick DNA 3'rA:T
Descriptor: DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*TP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA ligase 1, DNA/RNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-R(P*A)-D(P*GP*TP*CP*GP*GP*AP*C)-3'), ...
Authors:KanalElamparithi, B, Gulkis, M, Caglayan, M.
Deposit date:2023-12-17
Release date:2024-05-22
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Structures of LIG1 provide a mechanistic basis for understanding a lack of sugar discrimination against a ribonucleotide at the 3'-end of nick DNA.
J.Biol.Chem., 300, 2024
4LYL
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BU of 4lyl by Molmil
Crystal structure of uracil-DNA glycosylase from cod (Gadus morhua) in complex with the proteinaceous inhibitor UGI
Descriptor: Uracil-DNA glycosylase, Uracil-DNA glycosylase inhibitor
Authors:Assefa, N.G, Niiranen, L.M.K, Johnson, K.A, Leiros, H.-K.S, Smalas, A.O, Willassen, N.P, Moe, E.
Deposit date:2013-07-31
Release date:2014-08-13
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structural and biophysical analysis of interactions between cod and human uracil-DNA N-glycosylase (UNG) and UNG inhibitor (Ugi).
Acta Crystallogr.,Sect.D, 70, 2014

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数据于2025-07-09公开中

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