8VPG

CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA and Containing Quinoline-based SGI-1027 Analog 455

This is a non-PDB format compatible entry.

Summary for 8VPG

• Entry DOI: 10.2210/pdb8vpg/pdb
• Descriptor: Site-specific DNA-methyltransferase (adenine-specific), DNA Strand II, DNA Strand I, ... (5 entities in total)
• Functional Keywords: dna adenine methylation, protein-dna complex, transferase, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Clostridioides difficile; More
• Total number of polymer chains: 9
• Total formula weight: 232441.54

Authors

Zhou, J.,Horton, J.R.,Cheng, X. (deposition date: 2024-01-16, release date: 2024-09-25, Last modification date: 2024-10-02)

• Primary citation: Zhou, J.,Chen, Q.,Ren, R.,Yang, J.,Liu, B.,Horton, J.R.,Chang, C.,Li, C.,Maksoud, L.,Yang, Y.,Rotili, D.,Zhang, X.,Blumenthal, R.M.,Chen, T.,Gao, Y.,Valente, S.,Mai, A.,Cheng, X.; Quinoline-based compounds can inhibit diverse enzymes that act on DNA.; Biorxiv, 2024; PubMed: 38617249; DOI: 10.1101/2024.04.03.587980

Experimental method

X-RAY DIFFRACTION (3.05 Å)