PDB: 203978 resultsInfo pagesStatus searchChemie searchBIRD

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8TVT	Structure of human Cysteine desulfurase Nfs1 with L-propargylglycine bound to active site PLP in complex with ISD11, Acp1 and ISCU2 Descriptor: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ... Authors: Cygler, M, Boniecki, M.T. Deposit date: 2023-08-18 Release date: 2024-09-11 Method: X-RAY DIFFRACTION (2 Å) Cite: D-Cysteine impairs tumor growth by inhibiting cysteine desulfurase NFS1 To Be Published
5ZST	NifS from Hydrogenimonas thermopile in a persulfurated form Descriptor: Cysteine desulfurase Authors: Nakamura, R, Fujishiro, T, Takahashi, Y. Deposit date: 2018-04-29 Release date: 2019-05-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes. Febs J., 287, 2020
5JFB	Crystal structure of the scavenger receptor cysteine-rich domain 5 (SRCR5) from porcine CD163 Descriptor: Scavenger receptor cysteine-rich type 1 protein M130 Authors: Ma, H, Jiang, L, Qiao, S, Zhang, G, Li, R. Deposit date: 2016-04-19 Release date: 2017-03-22 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2 Å) Cite: The Crystal Structure of the Fifth Scavenger Receptor Cysteine-Rich Domain of Porcine CD163 Reveals an Important Residue Involved in Porcine Reproductive and Respiratory Syndrome Virus Infection J. Virol., 91, 2017
7XNZ	Native cystathionine beta-synthase of Mycobacterium tuberculosis. Descriptor: PYRIDOXAL-5'-PHOSPHATE, Putative cystathionine beta-synthase Rv1077 Authors: Bandyopadhyay, P, Pramanick, I, Biswas, R, Sabarinath, P.S, Sreedharan, S, Singh, S, Rajmani, R, Laxman, S, Dutta, S, Singh, A. Deposit date: 2022-04-30 Release date: 2022-05-25 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: S-Adenosylmethionine-responsive cystathionine beta-synthase modulates sulfur metabolism and redox balance in Mycobacterium tuberculosis. Sci Adv, 8, 2022
8OFK	Crystal structure of the cysteine-rich Gallus gallus urate oxidase in complex with the 8-azaxanthine inhibitor under reducing conditions (space group C 2 2 21) Descriptor: 1,2-ETHANEDIOL, 8-AZAXANTHINE, CHLORIDE ION, ... Authors: Di Palma, M, Chegkazi, M, Bui, S, Mori, G, Percudani, R, Steiner, R.A. Deposit date: 2023-03-15 Release date: 2024-01-17 Method: X-RAY DIFFRACTION (1.713 Å) Cite: Cysteine Enrichment Mediates Co-Option of Uricase in Reptilian Skin and Transition to Uricotelism. Mol.Biol.Evol., 40, 2023
6A6E	Crystal structure of thermostable Cysteine desulfurase (FiSufS) from thermophilic Fervidobacterium Islandicum AW-1 Descriptor: CITRIC ACID, Cysteine desulfurase, DI(HYDROXYETHYL)ETHER, ... Authors: Dhanasingh, I, Jin, H.S, Lee, D.W, Lee, S.H. Deposit date: 2018-06-27 Release date: 2019-10-09 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.09 Å) Cite: The sulfur formation system mediating extracellular cysteine-cystine recycling in Fervidobacterium islandicum AW-1 is associated with keratin degradation. Microb Biotechnol, 2020
5ZC1	X-ray diffraction analysis of the CsStefin-1 Descriptor: Cystatin-1 Authors: Jang, S.B, Park, S.Y. Deposit date: 2018-02-14 Release date: 2018-12-26 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.302708 Å) Cite: Structural basis of the cystein protease inhibitor Clonorchis sinensis Stefin-1. Biochem. Biophys. Res. Commun., 498, 2018
6D9Z	Structure of CysZ, a sulfate permease from Pseudomonas Denitrificans Descriptor: Sulfate transporter CysZ, octyl beta-D-glucopyranoside Authors: Sanghai, Z.A, Clarke, O.B, Liu, Q, Banerjee, S, Rajashankar, K.R, Hendrickson, W.A, Mancia, F. Deposit date: 2018-04-30 Release date: 2018-05-23 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.4021318 Å) Cite: Structure-based analysis of CysZ-mediated cellular uptake of sulfate. Elife, 7, 2018
3VSC	Crystal Structure of the K127A Mutant of O-Phosphoserine Sulfhydrylase Complexed with External Schiff Base of Pyridoxal 5'-Phosphate with O-Phospho-L-Serine Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, PHOSPHOSERINE, PYRIDOXAL-5'-PHOSPHATE, ... Authors: Nakamura, T, Kawai, Y, Kataoka, M, Ishikawa, K. Deposit date: 2012-04-24 Release date: 2012-05-16 Last modified: 2025-03-26 Method: X-RAY DIFFRACTION (2.07 Å) Cite: Structural analysis of the substrate recognition mechanism in O-phosphoserine sulfhydrylase from the hyperthermophilic archaeon Aeropyrum pernix K1 J.Mol.Biol., 422, 2012
2Y60	Isopenicillin N synthase with AC-D-methionine Descriptor: FE (III) ION, GLYCEROL, ISOPENICILLIN N SYNTHASE, ... Authors: Rutledge, P.J, Clifton, I.J, Ge, W. Deposit date: 2011-01-19 Release date: 2012-02-08 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: The Crystal Structure of Isopenicillin N Synthase with Delta((L)-Alpha-Aminoadipoyl)-(L)-Cysteinyl-(D)-Methionine Reveals Thioether Coordination to Iron. Arch.Biochem.Biophys., 516, 2011
3VSD	Crystal Structure of the K127A Mutant of O-Phosphoserine Sulfhydrylase Complexed with External Schiff Base of Pyridoxal 5'-Phosphate with O-Acetyl-L-Serine Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, O-ACETYLSERINE, PYRIDOXAL-5'-PHOSPHATE, ... Authors: Nakamura, T, Kawai, Y, Kataoka, M, Ishikawa, K. Deposit date: 2012-04-24 Release date: 2012-05-16 Last modified: 2025-03-26 Method: X-RAY DIFFRACTION (2.09 Å) Cite: Structural analysis of the substrate recognition mechanism in O-phosphoserine sulfhydrylase from the hyperthermophilic archaeon Aeropyrum pernix K1 J.Mol.Biol., 422, 2012
8DKE	Cryo-EM structure of cystinosin in a cytosol-open state Descriptor: Fab 3H5 Heavy chain, Fab 3H5 Kappa chain, Isoform 2 of Cystinosin Authors: Schmiege, P, Li, X. Deposit date: 2022-07-05 Release date: 2022-09-21 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (3.18 Å) Cite: Structure and mechanism of human cystine exporter cystinosin. Cell, 185, 2022
8DKW	Cryo-EM structure of cystinosin N288K mutant in a cytosol-open state at pH5.0 Descriptor: Fab 3H5 Heavy Chain, Fab 3H5 Kappa Chain, Isoform 2 of Cystinosin Authors: Schmiege, P, Li, X. Deposit date: 2022-07-06 Release date: 2022-09-21 Last modified: 2025-05-21 Method: ELECTRON MICROSCOPY (3.09 Å) Cite: Structure and mechanism of human cystine exporter cystinosin. Cell, 185, 2022
8DKI	Cryo-EM structure of cystinosin in a lumen-open state Descriptor: Fab 3H5 Heavy Chain, Fab 3H5 Kappa chain, Isoform 2 of Cystinosin Authors: Schmiege, P, Li, X. Deposit date: 2022-07-05 Release date: 2022-09-21 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (3.32 Å) Cite: Structure and mechanism of human cystine exporter cystinosin. Cell, 185, 2022
8DKX	Cryo-EM structure of cystinosin N288K mutant in a cytosol-open state at pH7.5 Descriptor: Fab 3H5 Heavy Chain, Fab 3H5 Kappa Chain, Isoform 2 of Cystinosin Authors: Schmiege, P, Li, X. Deposit date: 2022-07-06 Release date: 2022-09-21 Last modified: 2025-06-04 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structure and mechanism of human cystine exporter cystinosin. Cell, 185, 2022
8DYP	Crystal structure of human cystine transporter cystinosin Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Cystinosin, Nanobody P10, ... Authors: Guo, X, Feng, L. Deposit date: 2022-08-04 Release date: 2022-11-16 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Structure and mechanism of human cystine exporter cystinosin. Cell, 185, 2022
8OH8	Crystal structure of the cysteine-rich Gallus gallus urate oxidase in complex with the 8-azaxanthine inhibitor under reducing conditions (space group P 21 21 21) Descriptor: 1,2-ETHANEDIOL, 8-AZAXANTHINE, CHLORIDE ION, ... Authors: Di Palma, M, Chegkazi, M, Bui, S, Mori, G, Percudani, R, Steiner, R.A. Deposit date: 2023-03-20 Release date: 2024-01-17 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Cysteine Enrichment Mediates Co-Option of Uricase in Reptilian Skin and Transition to Uricotelism. Mol.Biol.Evol., 40, 2023
3IG5	Saccharomyces cerevisiae glutamate cysteine ligase in complex with Mg2+ and L-glutamate Descriptor: GLUTAMIC ACID, Glutamate-cysteine ligase, MAGNESIUM ION, ... Authors: Biterova, E, Barycki, J.J. Deposit date: 2009-07-27 Release date: 2009-09-01 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Mechanistic details of glutathione biosynthesis revealed by crystal structures of Saccharomyces cerevisiae glutamate cysteine ligase. J.Biol.Chem., 284, 2009
9JWC	Three-dimensional structure of homo-dimer of cystathione beta lyase/PLP/+L-alliin complex from lactobacillus delbrueckii(LdPatB) Descriptor: ALLIIN, PYRIDOXAL-5'-PHOSPHATE, cysteine-S-conjugate beta-lyase Authors: Liu, Y, Yang, C. Deposit date: 2024-10-10 Release date: 2024-11-20 Method: X-RAY DIFFRACTION (2.08 Å) Cite: Cystathionine beta-lyase(PatB)of Lactobacillus lactobacillus delbrueckii at 1.78 ? To Be Published
9JVA	Three-dimensional structure of homo-dimer of cystathione beta lyase/PLP complex from lactobacillus delbrueckii(LdPatB) Descriptor: PYRIDOXAL-5'-PHOSPHATE, cysteine-S-conjugate beta-lyase Authors: Liu, Y, Yang, C. Deposit date: 2024-10-08 Release date: 2024-11-20 Method: X-RAY DIFFRACTION (2.08 Å) Cite: Cystathionine beta-lyase(PatB)/PLP complex of Lactobacillus lactobacillus delbrueckii at 1.53 ANG To Be Published
5ZSP	NifS from Hydrogenimonas thermophila Descriptor: Cysteine desulfurase Authors: Nakamura, R, Fujishiro, T, Takahashi, Y. Deposit date: 2018-04-29 Release date: 2019-05-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.57 Å) Cite: Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes. Febs J., 287, 2020
3L0R	Crystal Structure of Salivary Cystatin from the Soft Tick Ornithodoros moubata Descriptor: CHLORIDE ION, Cystatin-2, GLYCEROL Authors: Rezacova, P, Brynda, J, Andersen, J.F, Salat, J, Kovarova, Z, Mares, M. Deposit date: 2009-12-10 Release date: 2010-06-30 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Crystal structure and functional characterization of an immunomodulatory salivary cystatin from the soft tick Ornithodoros moubata Biochem.J., 429, 2010
3ZKY	Isopenicillin N synthase with substrate analogue AhCmC Descriptor: FE (III) ION, GLYCEROL, ISOPENICILLIN N SYNTHASE, ... Authors: Daruzzaman, A, Clifton, I.J, Rutledge, P.J. Deposit date: 2013-01-25 Release date: 2013-03-20 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.45 Å) Cite: The Interaction of Isopenicillin N Synthase with Homologated Substrate Analogues Delta-(L-Alpha-Aminoadipoyl)-L-Homocysteinyl-D-Xaa Characterised by Protein Crystallography. Chembiochem, 14, 2013
1G96	HUMAN CYSTATIN C; DIMERIC FORM WITH 3D DOMAIN SWAPPING Descriptor: CHLORIDE ION, CYSTATIN C, GLYCEROL Authors: Janowski, R, Kozak, M, Jankowska, E, Grzonka, Z, Grubb, A, Abrahamson, M, Jaskolski, M. Deposit date: 2000-11-22 Release date: 2001-04-06 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Human cystatin C, an amyloidogenic protein, dimerizes through three-dimensional domain swapping. Nat.Struct.Biol., 8, 2001
3IG8	Saccharomyces cerevisiae glutamate cysteine ligase in complex with Mg2+, L-glutamate and ADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLUTAMIC ACID, Glutamate-cysteine ligase, ... Authors: Biterova, E, Barycki, J.J. Deposit date: 2009-07-27 Release date: 2009-09-01 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.69 Å) Cite: Mechanistic details of glutathione biosynthesis revealed by crystal structures of Saccharomyces cerevisiae glutamate cysteine ligase. J.Biol.Chem., 284, 2009

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